Project name: 4c93b8905336b21

Chain sequence(s)	A: GGGHKGG; C: GGGHKGG; B: GGGHKGG; E: GGGHKGG; D: GGGHKGG; G: GGGHKGG; F: GGGHKGG; I: GGGHKGG; H: GGGHKGG; K: GGGHKGG; J: GGGHKGG; M: GGGHKGG; L: GGGHKGG; O: GGGHKGG; N: GGGHKGG; Q: GGGHKGG; P: GGGHKGG; S: GGGHKGG; R: GGGHKGG; T: GGGHKGG
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,M,L,O,N,Q,P,S,R,T
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:05:32)
[INFO]       Main:     Simulation completed successfully.                                          (00:05:37)

• Minimal score value: -3.2139
• Maximal score value: -1.0576
• Average score: -1.7439
• Total score value: -244.1504

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-1.2228
2	G	A	-1.4195
3	G	A	-1.8017
4	H	A	-2.2681
5	K	A	-2.5027
6	G	A	-1.8806
7	G	A	-1.3745
1	G	B	-1.2115
2	G	B	-1.4677
3	G	B	-1.8968
4	H	B	-2.3902
5	K	B	-2.6792
6	G	B	-2.0608
7	G	B	-1.3992
1	G	C	-1.2732
2	G	C	-1.7438
3	G	C	-2.3643
4	H	C	-2.4924
5	K	C	-2.6933
6	G	C	-2.0257
7	G	C	-1.4650
1	G	D	-1.1484
2	G	D	-1.4566
3	G	D	-2.2679
4	H	D	-2.6378
5	K	D	-3.0342
6	G	D	-1.8315
7	G	D	-1.2545
1	G	E	-1.1986
2	G	E	-1.5102
3	G	E	-2.3726
4	H	E	-2.6271
5	K	E	-3.0316
6	G	E	-1.8505
7	G	E	-1.2526
1	G	F	-1.4150
2	G	F	-1.7499
3	G	F	-2.1937
4	H	F	-2.2920
5	K	F	-2.3100
6	G	F	-1.8539
7	G	F	-1.3741
1	G	G	-1.3931
2	G	G	-1.6264
3	G	G	-1.8510
4	H	G	-1.6906
5	K	G	-1.6831
6	G	G	-1.5422
7	G	G	-1.2061
1	G	H	-1.3520
2	G	H	-1.5463
3	G	H	-1.6188
4	H	H	-1.5446
5	K	H	-1.5015
6	G	H	-1.3372
7	G	H	-1.1937
1	G	I	-1.3153
2	G	I	-1.4604
3	G	I	-1.5061
4	H	I	-1.5386
5	K	I	-1.4917
6	G	I	-1.3386
7	G	I	-1.1900
1	G	J	-1.3651
2	G	J	-1.5658
3	G	J	-1.7308
4	H	J	-1.6149
5	K	J	-1.5533
6	G	J	-1.3389
7	G	J	-1.1849
1	G	K	-1.3940
2	G	K	-1.6335
3	G	K	-1.8207
4	H	K	-1.7365
5	K	K	-1.6068
6	G	K	-1.4137
7	G	K	-1.2230
1	G	L	-1.3576
2	G	L	-1.6483
3	G	L	-1.8248
4	H	L	-1.9410
5	K	L	-2.0761
6	G	L	-1.5895
7	G	L	-1.2961
1	G	M	-1.2491
2	G	M	-1.6784
3	G	M	-2.3542
4	H	M	-2.7251
5	K	M	-2.6881
6	G	M	-2.2093
7	G	M	-1.5326
1	G	N	-1.0576
2	G	N	-1.5394
3	G	N	-2.0268
4	H	N	-2.7136
5	K	N	-3.2139
6	G	N	-2.3721
7	G	N	-1.3642
1	G	O	-1.2050
2	G	O	-1.6180
3	G	O	-2.0470
4	H	O	-2.0698
5	K	O	-2.0848
6	G	O	-1.7815
7	G	O	-1.1526
1	G	P	-1.2682
2	G	P	-1.5192
3	G	P	-1.8290
4	H	P	-2.1415
5	K	P	-2.4294
6	G	P	-1.9269
7	G	P	-1.3649
1	G	Q	-1.2892
2	G	Q	-1.4872
3	G	Q	-1.8344
4	H	Q	-2.1226
5	K	Q	-2.2598
6	G	Q	-1.8442
7	G	Q	-1.4038
1	G	R	-1.2239
2	G	R	-1.3771
3	G	R	-1.7584
4	H	R	-2.3351
5	K	R	-2.6424
6	G	R	-1.8974
7	G	R	-1.3786
1	G	S	-1.2203
2	G	S	-1.3446
3	G	S	-1.5704
4	H	S	-1.8549
5	K	S	-2.1185
6	G	S	-1.7287
7	G	S	-1.3516
1	G	T	-1.2324
2	G	T	-1.3477
3	G	T	-1.5240
4	H	T	-1.8084
5	K	T	-1.9652
6	G	T	-1.6340
7	G	T	-1.2951