| Chain sequence(s) |
A: DELSRQPPRYPSPWANGQGEWAEAYQRAVAIVSQMTLDEKVNLTTGTGWELEKCVGQTGGVPRLNIGGMCLQDSPLGIRDSDYNSAFPAGVNVAATWDKNLAYLRGQAMGQEFSDKGIDVQLGPAAGPLGRSPDGGRNWEGFSPDPALTGVLFAETIKGIQDAGVVATAKHYILNEQEHFRQVAEAAGYGFNISDTISSNVDDKTIHEMYLWPFADAVRAGVGAIMCSYNQINNSYGCQNSYTLNKLLKAELGFQGFVMSDWGAHHSGVGSALAGLDMSMPGDRSRDSATSFWGTNLTIAVLNGTVPQWRVDDMAVRIMAAYYKVGRDRLYQPPNFSSWTRDEYGFKYFYPQEGPYEKVNHFVNVQRNHSEVIRKLGADSTVLLKNNNALPLTGKERKVAILGEDAGSNSRGANGCSDRGCDNGTLAMAWGSGTAEFPRMKTPEQAIQAEVLKHKGSVMAITDNWALSQVETLAKQASVSLVFVNSDAGEGYISVDGNEGDRNNLTLWKNGDNLIKAAANNCNNTIVVIHSVGPVLVDEWYDHPNVTAILWAGLPGQESGNSLADVLYGRVNPGAKSPFTWGKTREAYGDYLVRELNNGNGAPQDDFSEGVFIDYRGFDKRNETPIYEFGHGLSYTTFNYSGLHIQQLNASSNAQVATETGAAPTFGQVGNASDYVYPEGLTRISKFIYPWLNSTDLKASSGDPRYGVDTAEHVPEGATDGSPQPVLPAGGGSGGNPRLYDELIRVSVTVKNTGRVAGDAVPQLYVSLGGPNEPKVVLRKFDRLTLKPSEETKWTTTLTRRDLSNWDRAAQDWKINDEPKKVHVGSSSRQLPLHAALPKVQ
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | NT816A,DS817A,EY818A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 0.592986 kcal/mol |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:01)
[INFO] FoldX: Building mutant model (00:02:51)
[INFO] FoldX: Starting FoldX energy minimalization (00:04:18)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:07:32)
[INFO] Main: Simulation completed successfully. (00:07:39)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | D | A | -2.4320 | |
| 2 | E | A | -2.4519 | |
| 3 | L | A | -1.1336 | |
| 4 | S | A | -1.3363 | |
| 5 | R | A | -2.0400 | |
| 6 | Q | A | 0.0000 | |
| 7 | P | A | -0.8141 | |
| 8 | P | A | -0.8805 | |
| 9 | R | A | -0.6124 | |
| 10 | Y | A | -0.5235 | |
| 11 | P | A | 0.0000 | |
| 12 | S | A | 0.0000 | |
| 13 | P | A | -0.2012 | |
| 14 | W | A | -0.2612 | |
| 15 | A | A | 0.0000 | |
| 16 | N | A | -1.7217 | |
| 17 | G | A | 0.0000 | |
| 18 | Q | A | -2.0205 | |
| 19 | G | A | -2.1076 | |
| 20 | E | A | -2.6373 | |
| 21 | W | A | 0.0000 | |
| 22 | A | A | -2.5068 | |
| 23 | E | A | -3.0776 | |
| 24 | A | A | 0.0000 | |
| 25 | Y | A | -1.9513 | |
| 26 | Q | A | -2.4442 | |
| 27 | R | A | -2.3423 | |
| 28 | A | A | 0.0000 | |
| 29 | V | A | -0.9633 | |
| 30 | A | A | -0.9110 | |
| 31 | I | A | 0.0000 | |
| 32 | V | A | 0.0000 | |
| 33 | S | A | -0.9446 | |
| 34 | Q | A | -1.5582 | |
| 35 | M | A | 0.0000 | |
| 36 | T | A | -0.9300 | |
| 37 | L | A | 0.0000 | |
| 38 | D | A | -0.4066 | |
| 39 | E | A | -0.7613 | |
| 40 | K | A | 0.0000 | |
| 41 | V | A | 0.0000 | |
| 42 | N | A | -0.4015 | |
| 43 | L | A | 0.0000 | |
| 44 | T | A | 0.0000 | |
| 45 | T | A | 0.0000 | |
| 46 | G | A | 0.0000 | |
| 47 | T | A | 0.0000 | |
| 48 | G | A | 0.0000 | |
| 49 | W | A | -0.6309 | |
| 50 | E | A | -0.3681 | |
| 51 | L | A | 0.0000 | |
| 52 | E | A | -0.3794 | |
| 53 | K | A | -0.4785 | |
| 54 | C | A | 0.0000 | |
| 55 | V | A | -0.0613 | |
| 56 | G | A | 0.0000 | |
| 57 | Q | A | -0.3070 | |
| 58 | T | A | 0.0000 | |
| 59 | G | A | -0.4003 | |
| 60 | G | A | -0.8706 | |
| 61 | V | A | 0.0000 | |
| 62 | P | A | -1.6279 | |
| 63 | R | A | -2.3120 | |
| 64 | L | A | -1.4745 | |
| 65 | N | A | -1.7900 | |
| 66 | I | A | -1.0962 | |
| 67 | G | A | -0.8671 | |
| 68 | G | A | -0.4478 | |
| 69 | M | A | 0.0000 | |
| 70 | C | A | 0.0000 | |
| 71 | L | A | 0.0000 | |
| 72 | Q | A | 0.0000 | |
| 73 | D | A | 0.0000 | |
| 74 | S | A | 0.0000 | |
| 75 | P | A | 0.0000 | |
| 76 | L | A | 0.0000 | |
| 77 | G | A | 0.0000 | |
| 78 | I | A | 0.0000 | |
| 79 | R | A | -0.7358 | |
| 80 | D | A | -0.9436 | |
| 81 | S | A | 0.0000 | |
| 82 | D | A | -0.6611 | |
| 83 | Y | A | -0.0352 | |
| 84 | N | A | 0.0000 | |
| 85 | S | A | 0.0000 | |
| 86 | A | A | 0.0000 | |
| 87 | F | A | 0.0000 | |
| 88 | P | A | 0.0000 | |
| 89 | A | A | 0.0000 | |
| 90 | G | A | 0.0000 | |
| 91 | V | A | 0.0000 | |
| 92 | N | A | 0.0000 | |
| 93 | V | A | 0.0000 | |
| 94 | A | A | 0.0000 | |
| 95 | A | A | 0.0000 | |
| 96 | T | A | 0.0000 | |
| 97 | W | A | 0.0000 | |
| 98 | D | A | -1.2816 | |
| 99 | K | A | -1.7607 | |
| 100 | N | A | -1.6554 | |
| 101 | L | A | -0.7284 | |
| 102 | A | A | 0.0000 | |
| 103 | Y | A | -0.7760 | |
| 104 | L | A | 0.1470 | |
| 105 | R | A | 0.0000 | |
| 106 | G | A | 0.0000 | |
| 107 | Q | A | -0.8751 | |
| 108 | A | A | -0.5035 | |
| 109 | M | A | 0.0000 | |
| 110 | G | A | 0.0000 | |
| 111 | Q | A | -1.4263 | |
| 112 | E | A | 0.0000 | |
| 113 | F | A | 0.0000 | |
| 114 | S | A | -0.6269 | |
| 115 | D | A | -1.3373 | |
| 116 | K | A | 0.0000 | |
| 117 | G | A | 0.0000 | |
| 118 | I | A | 0.0000 | |
| 119 | D | A | 0.0000 | |
| 120 | V | A | 0.0000 | |
| 121 | Q | A | 0.0000 | |
| 122 | L | A | 0.0000 | |
| 123 | G | A | 0.0000 | |
| 124 | P | A | 0.0000 | |
| 125 | A | A | 0.0000 | |
| 126 | A | A | 0.0000 | |
| 127 | G | A | -0.0997 | |
| 128 | P | A | 0.0000 | |
| 129 | L | A | 0.0000 | |
| 130 | G | A | -0.1216 | |
| 131 | R | A | 0.0000 | |
| 132 | S | A | 0.0000 | |
| 133 | P | A | 0.0000 | |
| 134 | D | A | 0.0000 | |
| 135 | G | A | 0.0000 | |
| 136 | G | A | 0.0000 | |
| 137 | R | A | 0.0000 | |
| 138 | N | A | -0.1959 | |
| 139 | W | A | 0.0000 | |
| 140 | E | A | 0.0000 | |
| 141 | G | A | 0.0000 | |
| 142 | F | A | 0.0000 | |
| 143 | S | A | 0.0000 | |
| 144 | P | A | 0.0000 | |
| 145 | D | A | 0.0000 | |
| 146 | P | A | 0.0000 | |
| 147 | A | A | 0.0000 | |
| 148 | L | A | 0.0000 | |
| 149 | T | A | 0.0000 | |
| 150 | G | A | 0.0000 | |
| 151 | V | A | -0.0928 | |
| 152 | L | A | 0.0000 | |
| 153 | F | A | 0.0000 | |
| 154 | A | A | -0.6657 | |
| 155 | E | A | -0.9952 | |
| 156 | T | A | 0.0000 | |
| 157 | I | A | 0.0000 | |
| 158 | K | A | -1.5077 | |
| 159 | G | A | 0.0000 | |
| 160 | I | A | 0.0000 | |
| 161 | Q | A | -1.4641 | |
| 162 | D | A | -2.2554 | |
| 163 | A | A | -1.1214 | |
| 164 | G | A | 0.0000 | |
| 165 | V | A | 0.0000 | |
| 166 | V | A | 0.0000 | |
| 167 | A | A | 0.0000 | |
| 168 | T | A | 0.0000 | |
| 169 | A | A | 0.0000 | |
| 170 | K | A | 0.0000 | |
| 171 | H | A | 0.0000 | |
| 172 | Y | A | 0.0000 | |
| 173 | I | A | 0.0000 | |
| 174 | L | A | 0.0000 | |
| 175 | N | A | 0.0000 | |
| 176 | E | A | 0.0000 | |
| 177 | Q | A | 0.0000 | |
| 178 | E | A | 0.0000 | |
| 179 | H | A | -0.5580 | |
| 180 | F | A | 0.0000 | |
| 181 | R | A | 0.0000 | |
| 182 | Q | A | -0.1525 | |
| 183 | V | A | -0.0032 | |
| 184 | A | A | -0.1583 | |
| 185 | E | A | -0.1468 | |
| 186 | A | A | 0.0000 | |
| 187 | A | A | -0.4610 | |
| 188 | G | A | -0.4390 | |
| 189 | Y | A | -0.1353 | |
| 190 | G | A | -0.5840 | |
| 191 | F | A | -0.8435 | |
| 192 | N | A | -1.6161 | |
| 193 | I | A | 0.0000 | |
| 194 | S | A | -1.0432 | |
| 195 | D | A | -0.9324 | |
| 196 | T | A | 0.0000 | |
| 197 | I | A | 0.0000 | |
| 198 | S | A | 0.0000 | |
| 199 | S | A | 0.0000 | |
| 200 | N | A | 0.0000 | |
| 201 | V | A | 0.0000 | |
| 202 | D | A | -1.5373 | |
| 203 | D | A | -1.4268 | |
| 204 | K | A | -1.5884 | |
| 205 | T | A | 0.0000 | |
| 206 | I | A | 0.0000 | |
| 207 | H | A | 0.0000 | |
| 208 | E | A | -0.5213 | |
| 209 | M | A | 0.0000 | |
| 210 | Y | A | 0.0000 | |
| 211 | L | A | 0.0000 | |
| 212 | W | A | 0.0000 | |
| 213 | P | A | 0.0000 | |
| 214 | F | A | 0.0000 | |
| 215 | A | A | 0.0000 | |
| 216 | D | A | -0.6825 | |
| 217 | A | A | 0.0000 | |
| 218 | V | A | 0.0000 | |
| 219 | R | A | -1.5472 | |
| 220 | A | A | -1.0178 | |
| 221 | G | A | -1.1489 | |
| 222 | V | A | 0.0000 | |
| 223 | G | A | 0.0000 | |
| 224 | A | A | 0.0000 | |
| 225 | I | A | 0.0000 | |
| 226 | M | A | 0.0000 | |
| 227 | C | A | 0.0000 | |
| 228 | S | A | 0.0000 | |
| 229 | Y | A | -0.0427 | |
| 230 | N | A | 0.0000 | |
| 231 | Q | A | 0.0000 | |
| 232 | I | A | 0.0000 | |
| 233 | N | A | 0.0000 | |
| 234 | N | A | -0.7804 | |
| 235 | S | A | -0.6007 | |
| 236 | Y | A | -0.2415 | |
| 237 | G | A | 0.0000 | |
| 238 | C | A | 0.0000 | |
| 239 | Q | A | -0.4198 | |
| 240 | N | A | 0.0000 | |
| 241 | S | A | 0.0000 | |
| 242 | Y | A | -0.1633 | |
| 243 | T | A | 0.0000 | |
| 244 | L | A | 0.0000 | |
| 245 | N | A | 0.0000 | |
| 246 | K | A | -0.2003 | |
| 247 | L | A | 0.0000 | |
| 248 | L | A | 0.0000 | |
| 249 | K | A | 0.0000 | |
| 250 | A | A | -0.0690 | |
| 251 | E | A | 0.0000 | |
| 252 | L | A | 0.0000 | |
| 253 | G | A | -0.5936 | |
| 254 | F | A | 0.0000 | |
| 255 | Q | A | 0.0000 | |
| 256 | G | A | 0.0000 | |
| 257 | F | A | 0.0000 | |
| 258 | V | A | 0.0000 | |
| 259 | M | A | 0.0000 | |
| 260 | S | A | 0.0000 | |
| 261 | D | A | -0.1589 | |
| 262 | W | A | -0.2288 | |
| 263 | G | A | -1.0453 | |
| 264 | A | A | 0.0000 | |
| 265 | H | A | 0.0000 | |
| 266 | H | A | -1.1045 | |
| 267 | S | A | -0.5417 | |
| 268 | G | A | -0.0989 | |
| 269 | V | A | 0.1628 | |
| 270 | G | A | -0.3102 | |
| 271 | S | A | 0.0000 | |
| 272 | A | A | 0.0000 | |
| 273 | L | A | 0.0000 | |
| 274 | A | A | 0.0000 | |
| 275 | G | A | 0.0000 | |
| 276 | L | A | 0.0000 | |
| 277 | D | A | 0.0000 | |
| 278 | M | A | 0.0000 | |
| 279 | S | A | 0.0000 | |
| 280 | M | A | 0.0000 | |
| 281 | P | A | 0.0000 | |
| 282 | G | A | 0.0000 | |
| 283 | D | A | 0.0000 | |
| 284 | R | A | -2.2017 | |
| 285 | S | A | -2.0783 | |
| 286 | R | A | -2.8429 | |
| 287 | D | A | -2.1097 | |
| 288 | S | A | -1.5224 | |
| 289 | A | A | -0.9600 | |
| 290 | T | A | -0.9314 | |
| 291 | S | A | 0.0000 | |
| 292 | F | A | -0.3350 | |
| 293 | W | A | 0.0000 | |
| 294 | G | A | 0.0000 | |
| 295 | T | A | -0.1306 | |
| 296 | N | A | -0.4287 | |
| 297 | L | A | 0.0000 | |
| 298 | T | A | 0.0000 | |
| 299 | I | A | 0.0000 | |
| 300 | A | A | 0.0000 | |
| 301 | V | A | 0.0000 | |
| 302 | L | A | -0.6862 | |
| 303 | N | A | -1.0493 | |
| 304 | G | A | -0.8688 | |
| 305 | T | A | -0.5903 | |
| 306 | V | A | 0.0000 | |
| 307 | P | A | -0.6883 | |
| 308 | Q | A | -1.0283 | |
| 309 | W | A | 0.0000 | |
| 310 | R | A | 0.0000 | |
| 311 | V | A | 0.0000 | |
| 312 | D | A | 0.0000 | |
| 313 | D | A | 0.0000 | |
| 314 | M | A | 0.0000 | |
| 315 | A | A | 0.0000 | |
| 316 | V | A | 0.0000 | |
| 317 | R | A | 0.0000 | |
| 318 | I | A | 0.0000 | |
| 319 | M | A | 0.0000 | |
| 320 | A | A | 0.0000 | |
| 321 | A | A | 0.0000 | |
| 322 | Y | A | 0.0000 | |
| 323 | Y | A | -1.2180 | |
| 324 | K | A | -1.3682 | |
| 325 | V | A | -0.6326 | |
| 326 | G | A | -0.7549 | |
| 327 | R | A | 0.0000 | |
| 328 | D | A | -1.5504 | |
| 329 | R | A | -1.7233 | |
| 330 | L | A | -0.1348 | |
| 331 | Y | A | -0.5910 | |
| 332 | Q | A | -1.2825 | |
| 333 | P | A | -0.9027 | |
| 334 | P | A | 0.0000 | |
| 335 | N | A | 0.0000 | |
| 336 | F | A | 0.0000 | |
| 337 | S | A | 0.0000 | |
| 338 | S | A | 0.0000 | |
| 339 | W | A | -0.1724 | |
| 340 | T | A | -1.1436 | |
| 341 | R | A | -2.0209 | |
| 342 | D | A | -2.9160 | |
| 343 | E | A | -3.0103 | |
| 344 | Y | A | -1.4735 | |
| 345 | G | A | -1.1321 | |
| 346 | F | A | -0.4192 | |
| 347 | K | A | -1.2235 | |
| 348 | Y | A | -0.4446 | |
| 349 | F | A | 0.0000 | |
| 350 | Y | A | 0.5647 | |
| 351 | P | A | -0.3711 | |
| 352 | Q | A | -0.9663 | |
| 353 | E | A | -1.0367 | |
| 354 | G | A | -1.1252 | |
| 355 | P | A | -0.7271 | |
| 356 | Y | A | -0.0135 | |
| 357 | E | A | -1.7879 | |
| 358 | K | A | -2.2011 | |
| 359 | V | A | 0.0000 | |
| 360 | N | A | 0.0000 | |
| 361 | H | A | -0.9035 | |
| 362 | F | A | 0.0604 | |
| 363 | V | A | 0.0720 | |
| 364 | N | A | -1.2580 | |
| 365 | V | A | 0.0000 | |
| 366 | Q | A | -1.5942 | |
| 367 | R | A | -2.9031 | |
| 368 | N | A | -2.3477 | |
| 369 | H | A | 0.0000 | |
| 370 | S | A | -1.9107 | |
| 371 | E | A | -2.7853 | |
| 372 | V | A | -1.3310 | |
| 373 | I | A | 0.0000 | |
| 374 | R | A | -2.0145 | |
| 375 | K | A | -2.0066 | |
| 376 | L | A | 0.0000 | |
| 377 | G | A | 0.0000 | |
| 378 | A | A | 0.0000 | |
| 379 | D | A | 0.0000 | |
| 380 | S | A | 0.0000 | |
| 381 | T | A | 0.0000 | |
| 382 | V | A | 0.0000 | |
| 383 | L | A | 0.0000 | |
| 384 | L | A | 0.0000 | |
| 385 | K | A | -1.0048 | |
| 386 | N | A | -1.3913 | |
| 387 | N | A | -2.1944 | |
| 388 | N | A | -2.0539 | |
| 389 | A | A | -1.2358 | |
| 390 | L | A | 0.0000 | |
| 391 | P | A | -0.6844 | |
| 392 | L | A | 0.0000 | |
| 393 | T | A | -0.7043 | |
| 394 | G | A | 0.0000 | |
| 395 | K | A | -2.8171 | |
| 396 | E | A | -2.4416 | |
| 397 | R | A | -3.1940 | |
| 398 | K | A | -1.9970 | |
| 399 | V | A | 0.0000 | |
| 400 | A | A | 0.0000 | |
| 401 | I | A | 0.0000 | |
| 402 | L | A | 0.0000 | |
| 403 | G | A | 0.0000 | |
| 404 | E | A | -0.9092 | |
| 405 | D | A | 0.0000 | |
| 406 | A | A | 0.0000 | |
| 407 | G | A | 0.0000 | |
| 408 | S | A | -0.9287 | |
| 409 | N | A | -1.2521 | |
| 410 | S | A | -1.3481 | |
| 411 | R | A | -2.2815 | |
| 412 | G | A | -1.7006 | |
| 413 | A | A | -1.3992 | |
| 414 | N | A | -1.7190 | |
| 415 | G | A | -1.6679 | |
| 416 | C | A | 0.0000 | |
| 417 | S | A | -0.6388 | |
| 418 | D | A | -0.8092 | |
| 419 | R | A | 0.0000 | |
| 420 | G | A | -0.1940 | |
| 421 | C | A | -0.6036 | |
| 422 | D | A | 0.0000 | |
| 423 | N | A | -0.7751 | |
| 424 | G | A | 0.0000 | |
| 425 | T | A | 0.0000 | |
| 426 | L | A | 0.0000 | |
| 427 | A | A | 0.0000 | |
| 428 | M | A | 0.0000 | |
| 429 | A | A | 0.0000 | |
| 430 | W | A | 0.0000 | |
| 431 | G | A | 0.0000 | |
| 432 | S | A | -0.2233 | |
| 433 | G | A | 0.0000 | |
| 434 | T | A | 0.0000 | |
| 435 | A | A | 0.0000 | |
| 436 | E | A | -0.9005 | |
| 437 | F | A | 0.0000 | |
| 438 | P | A | -0.6820 | |
| 439 | R | A | -1.1666 | |
| 440 | M | A | -0.7678 | |
| 441 | K | A | -0.8633 | |
| 442 | T | A | 0.0000 | |
| 443 | P | A | 0.0000 | |
| 444 | E | A | -0.7940 | |
| 445 | Q | A | -1.1773 | |
| 446 | A | A | 0.0000 | |
| 447 | I | A | 0.0000 | |
| 448 | Q | A | -0.2911 | |
| 449 | A | A | -0.4194 | |
| 450 | E | A | 0.0000 | |
| 451 | V | A | 0.0000 | |
| 452 | L | A | -0.2697 | |
| 453 | K | A | -1.9033 | |
| 454 | H | A | -2.5392 | |
| 455 | K | A | -2.6610 | |
| 456 | G | A | -2.1922 | |
| 457 | S | A | -0.8419 | |
| 458 | V | A | 0.0812 | |
| 459 | M | A | 0.7348 | |
| 460 | A | A | -0.0717 | |
| 461 | I | A | 0.0000 | |
| 462 | T | A | -0.8396 | |
| 463 | D | A | -1.3731 | |
| 464 | N | A | 0.0000 | |
| 465 | W | A | 0.3921 | |
| 466 | A | A | -0.2527 | |
| 467 | L | A | -0.4223 | |
| 468 | S | A | -0.7072 | |
| 469 | Q | A | -1.4161 | |
| 470 | V | A | 0.0000 | |
| 471 | E | A | -2.1476 | |
| 472 | T | A | -1.6664 | |
| 473 | L | A | 0.0000 | |
| 474 | A | A | 0.0000 | |
| 475 | K | A | -3.0235 | |
| 476 | Q | A | -2.4840 | |
| 477 | A | A | -1.8103 | |
| 478 | S | A | -1.8041 | |
| 479 | V | A | 0.0000 | |
| 480 | S | A | 0.0000 | |
| 481 | L | A | 0.0000 | |
| 482 | V | A | 0.0000 | |
| 483 | F | A | 0.0000 | |
| 484 | V | A | 0.0000 | |
| 485 | N | A | 0.0000 | |
| 486 | S | A | 0.0000 | |
| 487 | D | A | 0.0000 | |
| 488 | A | A | 0.0000 | |
| 489 | G | A | 0.0000 | |
| 490 | E | A | 0.0000 | |
| 491 | G | A | 0.0000 | |
| 492 | Y | A | 0.5690 | |
| 493 | I | A | 0.2714 | |
| 494 | S | A | -0.5282 | |
| 495 | V | A | -0.9736 | |
| 496 | D | A | -2.1938 | |
| 497 | G | A | -1.6504 | |
| 498 | N | A | 0.0000 | |
| 499 | E | A | -0.8668 | |
| 500 | G | A | 0.0000 | |
| 501 | D | A | 0.0000 | |
| 502 | R | A | 0.0000 | |
| 503 | N | A | -2.2519 | |
| 504 | N | A | -1.7303 | |
| 505 | L | A | 0.0000 | |
| 506 | T | A | -0.6498 | |
| 507 | L | A | 0.0000 | |
| 508 | W | A | 0.0000 | |
| 509 | K | A | -0.8983 | |
| 510 | N | A | -0.7047 | |
| 511 | G | A | 0.0000 | |
| 512 | D | A | -1.4453 | |
| 513 | N | A | -1.1621 | |
| 514 | L | A | 0.0000 | |
| 515 | I | A | 0.0000 | |
| 516 | K | A | -1.7094 | |
| 517 | A | A | 0.0000 | |
| 518 | A | A | 0.0000 | |
| 519 | A | A | 0.0000 | |
| 520 | N | A | -2.2536 | |
| 521 | N | A | -2.3039 | |
| 522 | C | A | 0.0000 | |
| 523 | N | A | -2.1157 | |
| 524 | N | A | -1.5167 | |
| 525 | T | A | 0.0000 | |
| 526 | I | A | 0.0000 | |
| 527 | V | A | 0.0000 | |
| 528 | V | A | 0.0000 | |
| 529 | I | A | 0.0000 | |
| 530 | H | A | 0.0000 | |
| 531 | S | A | 0.0000 | |
| 532 | V | A | 0.0000 | |
| 533 | G | A | 0.0000 | |
| 534 | P | A | 0.0000 | |
| 535 | V | A | 0.0000 | |
| 536 | L | A | -0.8918 | |
| 537 | V | A | 0.0000 | |
| 538 | D | A | -2.6526 | |
| 539 | E | A | -2.5786 | |
| 540 | W | A | 0.0000 | |
| 541 | Y | A | -1.5551 | |
| 542 | D | A | -2.3945 | |
| 543 | H | A | -1.9261 | |
| 544 | P | A | -1.4159 | |
| 545 | N | A | -1.7441 | |
| 546 | V | A | 0.0000 | |
| 547 | T | A | 0.0000 | |
| 548 | A | A | 0.0000 | |
| 549 | I | A | 0.0000 | |
| 550 | L | A | 0.0000 | |
| 551 | W | A | 0.0000 | |
| 552 | A | A | 0.0000 | |
| 553 | G | A | 0.0000 | |
| 554 | L | A | 0.0000 | |
| 555 | P | A | 0.0000 | |
| 556 | G | A | 0.0000 | |
| 557 | Q | A | 0.0000 | |
| 558 | E | A | 0.0000 | |
| 559 | S | A | 0.0000 | |
| 560 | G | A | 0.0000 | |
| 561 | N | A | -0.7113 | |
| 562 | S | A | 0.0000 | |
| 563 | L | A | 0.0000 | |
| 564 | A | A | 0.0000 | |
| 565 | D | A | 0.0000 | |
| 566 | V | A | 0.0000 | |
| 567 | L | A | 0.0000 | |
| 568 | Y | A | -0.5617 | |
| 569 | G | A | -1.0562 | |
| 570 | R | A | -1.8716 | |
| 571 | V | A | -1.0275 | |
| 572 | N | A | -0.4069 | |
| 573 | P | A | 0.0000 | |
| 574 | G | A | 0.0000 | |
| 575 | A | A | 0.0000 | |
| 576 | K | A | -0.1558 | |
| 577 | S | A | 0.0000 | |
| 578 | P | A | 0.0000 | |
| 579 | F | A | 0.0000 | |
| 580 | T | A | 0.0000 | |
| 581 | W | A | 0.0000 | |
| 582 | G | A | 0.0000 | |
| 583 | K | A | -1.9465 | |
| 584 | T | A | -1.4729 | |
| 585 | R | A | 0.0000 | |
| 586 | E | A | -2.4549 | |
| 587 | A | A | 0.0000 | |
| 588 | Y | A | 0.0000 | |
| 589 | G | A | 0.0000 | |
| 590 | D | A | -2.1506 | |
| 591 | Y | A | -1.2054 | |
| 592 | L | A | 0.0000 | |
| 593 | V | A | 0.0000 | |
| 594 | R | A | -1.8522 | |
| 595 | E | A | -2.3732 | |
| 596 | L | A | -1.9608 | |
| 597 | N | A | -2.2579 | |
| 598 | N | A | -1.8105 | |
| 599 | G | A | -1.8505 | |
| 600 | N | A | -2.2905 | |
| 601 | G | A | -1.6046 | |
| 602 | A | A | 0.0000 | |
| 603 | P | A | 0.0000 | |
| 604 | Q | A | 0.0000 | |
| 605 | D | A | 0.0000 | |
| 606 | D | A | -1.7889 | |
| 607 | F | A | 0.0000 | |
| 608 | S | A | -0.7622 | |
| 609 | E | A | 0.0000 | |
| 610 | G | A | -0.4648 | |
| 611 | V | A | 0.0166 | |
| 612 | F | A | -0.0997 | |
| 613 | I | A | 0.0000 | |
| 614 | D | A | 0.0000 | |
| 615 | Y | A | 0.0000 | |
| 616 | R | A | 0.0000 | |
| 617 | G | A | 0.0000 | |
| 618 | F | A | 0.0000 | |
| 619 | D | A | -2.0067 | |
| 620 | K | A | -2.5199 | |
| 621 | R | A | -2.3678 | |
| 622 | N | A | -2.3783 | |
| 623 | E | A | -1.6896 | |
| 624 | T | A | -0.8641 | |
| 625 | P | A | -0.6906 | |
| 626 | I | A | -0.5317 | |
| 627 | Y | A | 0.0000 | |
| 628 | E | A | -0.4794 | |
| 629 | F | A | 0.0000 | |
| 630 | G | A | 0.0000 | |
| 631 | H | A | -0.3424 | |
| 632 | G | A | 0.0135 | |
| 633 | L | A | 0.3409 | |
| 634 | S | A | 0.2163 | |
| 635 | Y | A | -0.1296 | |
| 636 | T | A | 0.0000 | |
| 637 | T | A | -0.4119 | |
| 638 | F | A | -0.8325 | |
| 639 | N | A | -1.5445 | |
| 640 | Y | A | -1.0166 | |
| 641 | S | A | -0.8766 | |
| 642 | G | A | -0.6462 | |
| 643 | L | A | -0.6928 | |
| 644 | H | A | -1.1616 | |
| 645 | I | A | -0.8505 | |
| 646 | Q | A | -1.7212 | |
| 647 | Q | A | -2.1355 | |
| 648 | L | A | -1.3345 | |
| 649 | N | A | -1.7592 | |
| 650 | A | A | -1.4553 | |
| 651 | S | A | -1.3104 | |
| 652 | S | A | -1.3157 | |
| 653 | N | A | -1.7294 | |
| 654 | A | A | -1.3155 | |
| 655 | Q | A | -1.5287 | |
| 656 | V | A | -0.8420 | |
| 657 | A | A | -0.7214 | |
| 658 | T | A | -0.9888 | |
| 659 | E | A | -1.9597 | |
| 660 | T | A | -1.3650 | |
| 661 | G | A | -1.1494 | |
| 662 | A | A | -0.6255 | |
| 663 | A | A | -0.5406 | |
| 664 | P | A | -0.3275 | |
| 665 | T | A | -0.4449 | |
| 666 | F | A | -0.5814 | |
| 667 | G | A | -1.3112 | |
| 668 | Q | A | -1.7639 | |
| 669 | V | A | -1.2415 | |
| 670 | G | A | -1.6354 | |
| 671 | N | A | -2.1421 | |
| 672 | A | A | -1.6790 | |
| 673 | S | A | -1.7055 | |
| 674 | D | A | -2.1654 | |
| 675 | Y | A | 0.0000 | |
| 676 | V | A | -0.7233 | |
| 677 | Y | A | -0.2269 | |
| 678 | P | A | -0.8891 | |
| 679 | E | A | -1.7867 | |
| 680 | G | A | -1.3922 | |
| 681 | L | A | -0.8941 | |
| 682 | T | A | -1.1118 | |
| 683 | R | A | -1.7517 | |
| 684 | I | A | -0.9697 | |
| 685 | S | A | -0.7920 | |
| 686 | K | A | -0.8600 | |
| 687 | F | A | -0.2286 | |
| 688 | I | A | 0.0000 | |
| 689 | Y | A | 0.1249 | |
| 690 | P | A | 0.0000 | |
| 691 | W | A | 0.0548 | |
| 692 | L | A | 0.0000 | |
| 693 | N | A | -1.4889 | |
| 694 | S | A | -1.3915 | |
| 695 | T | A | -1.7338 | |
| 696 | D | A | -2.3175 | |
| 697 | L | A | -1.7477 | |
| 698 | K | A | -2.6371 | |
| 699 | A | A | -1.6928 | |
| 700 | S | A | 0.0000 | |
| 701 | S | A | -1.5342 | |
| 702 | G | A | -1.5386 | |
| 703 | D | A | -1.7101 | |
| 704 | P | A | -1.5473 | |
| 705 | R | A | -2.2214 | |
| 706 | Y | A | -1.4068 | |
| 707 | G | A | -1.0870 | |
| 708 | V | A | -0.7036 | |
| 709 | D | A | -2.0660 | |
| 710 | T | A | -1.4472 | |
| 711 | A | A | -1.7672 | |
| 712 | E | A | -2.6612 | |
| 713 | H | A | -2.0364 | |
| 714 | V | A | -1.3608 | |
| 715 | P | A | -1.5464 | |
| 716 | E | A | -2.2763 | |
| 717 | G | A | -1.2340 | |
| 718 | A | A | 0.0000 | |
| 719 | T | A | -0.8077 | |
| 720 | D | A | -1.0371 | |
| 721 | G | A | -0.6849 | |
| 722 | S | A | -0.5755 | |
| 723 | P | A | -1.0076 | |
| 724 | Q | A | -1.0091 | |
| 725 | P | A | -1.0201 | |
| 726 | V | A | -0.4124 | |
| 727 | L | A | -0.2058 | |
| 728 | P | A | -0.2425 | |
| 729 | A | A | 0.0000 | |
| 730 | G | A | 0.0000 | |
| 731 | G | A | -0.4324 | |
| 732 | G | A | -0.8014 | |
| 733 | S | A | -1.1174 | |
| 734 | G | A | 0.0000 | |
| 735 | G | A | 0.0000 | |
| 736 | N | A | -0.5666 | |
| 737 | P | A | -0.9553 | |
| 738 | R | A | -1.2364 | |
| 739 | L | A | 0.0000 | |
| 740 | Y | A | -0.5381 | |
| 741 | D | A | 0.0000 | |
| 742 | E | A | -1.7921 | |
| 743 | L | A | 0.0000 | |
| 744 | I | A | 0.0000 | |
| 745 | R | A | -1.4549 | |
| 746 | V | A | 0.0000 | |
| 747 | S | A | -0.9589 | |
| 748 | V | A | 0.0000 | |
| 749 | T | A | -1.7153 | |
| 750 | V | A | 0.0000 | |
| 751 | K | A | -2.8398 | |
| 752 | N | A | 0.0000 | |
| 753 | T | A | -1.4759 | |
| 754 | G | A | -1.1251 | |
| 755 | R | A | -1.6632 | |
| 756 | V | A | -0.3413 | |
| 757 | A | A | -0.9522 | |
| 758 | G | A | -0.5241 | |
| 759 | D | A | -0.5522 | |
| 760 | A | A | 0.0000 | |
| 761 | V | A | 0.0000 | |
| 762 | P | A | 0.0000 | |
| 763 | Q | A | 0.0000 | |
| 764 | L | A | 0.0000 | |
| 765 | Y | A | 0.0000 | |
| 766 | V | A | 0.0000 | |
| 767 | S | A | -0.9023 | |
| 768 | L | A | 0.0000 | |
| 769 | G | A | -0.7189 | |
| 770 | G | A | -0.7712 | |
| 771 | P | A | -1.2100 | |
| 772 | N | A | -1.7822 | |
| 773 | E | A | -1.4311 | |
| 774 | P | A | 0.0000 | |
| 775 | K | A | -2.3054 | |
| 776 | V | A | 0.0000 | |
| 777 | V | A | 0.0000 | |
| 778 | L | A | 0.0000 | |
| 779 | R | A | -0.2855 | |
| 780 | K | A | -0.4721 | |
| 781 | F | A | 0.0000 | |
| 782 | D | A | -1.1895 | |
| 783 | R | A | -0.8996 | |
| 784 | L | A | -0.7263 | |
| 785 | T | A | -0.9832 | |
| 786 | L | A | 0.0000 | |
| 787 | K | A | -2.7504 | |
| 788 | P | A | -2.0227 | |
| 789 | S | A | -2.0684 | |
| 790 | E | A | -3.1841 | |
| 791 | E | A | -3.6264 | |
| 792 | T | A | -2.1978 | |
| 793 | K | A | -2.2213 | |
| 794 | W | A | 0.0000 | |
| 795 | T | A | -0.7844 | |
| 796 | T | A | -0.7213 | |
| 797 | T | A | -0.8896 | |
| 798 | L | A | 0.0000 | |
| 799 | T | A | -0.8151 | |
| 800 | R | A | -0.9655 | |
| 801 | R | A | 0.0000 | |
| 802 | D | A | 0.0000 | |
| 803 | L | A | 0.0000 | |
| 804 | S | A | 0.0000 | |
| 805 | N | A | -0.9812 | |
| 806 | W | A | 0.0000 | |
| 807 | D | A | -1.5946 | |
| 808 | R | A | -2.0851 | |
| 809 | A | A | -0.7842 | |
| 810 | A | A | -0.8809 | |
| 811 | Q | A | -1.2547 | |
| 812 | D | A | -1.2767 | |
| 813 | W | A | -1.1527 | |
| 814 | K | A | -1.7486 | |
| 815 | I | A | -0.7533 | |
| 816 | T | A | -0.3761 | mutated: NT816A |
| 817 | S | A | -0.2068 | mutated: DS817A |
| 818 | Y | A | 0.4694 | mutated: EY818A |
| 819 | P | A | -0.3860 | |
| 820 | K | A | -0.7702 | |
| 821 | K | A | -1.3508 | |
| 822 | V | A | 0.0000 | |
| 823 | H | A | -0.7753 | |
| 824 | V | A | 0.0000 | |
| 825 | G | A | 0.0000 | |
| 826 | S | A | -0.4479 | |
| 827 | S | A | 0.0000 | |
| 828 | S | A | 0.0000 | |
| 829 | R | A | -1.2309 | |
| 830 | Q | A | -1.0666 | |
| 831 | L | A | -0.6226 | |
| 832 | P | A | -0.7181 | |
| 833 | L | A | -0.5426 | |
| 834 | H | A | -1.1699 | |
| 835 | A | A | -0.7373 | |
| 836 | A | A | -0.7408 | |
| 837 | L | A | 0.0000 | |
| 838 | P | A | -1.3100 | |
| 839 | K | A | -2.0235 | |
| 840 | V | A | -1.5584 | |
| 841 | Q | A | -1.7780 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine