Project name: 4d4d9bddd6d25fd

Chain sequence(s)	H: EVQLLESGGGLVQPGGSLRLSCAASGSIFSINAMHWFRQAPGKQRELVAVITSGGSTIYAESVKGRFTISRDNSKNTVYLQMNSLRPEDTAVYYCNAHVGLKVPTIQELSLGFGSWGQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:45)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:46)

• Minimal score value: -2.7021
• Maximal score value: 2.1875
• Average score: -0.3096
• Total score value: -39.0135

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.2333
2	V	H	0.0000
3	Q	H	-1.2336
4	L	H	0.0000
5	L	H	1.0329
6	E	H	0.0000
7	S	H	-0.1360
8	G	H	-0.6023
9	G	H	0.2429
11	G	H	0.8916
12	L	H	1.5116
13	V	H	0.0029
14	Q	H	-1.3432
15	P	H	-1.7560
16	G	H	-1.3870
17	G	H	-0.9083
18	S	H	-0.9684
19	L	H	-0.4557
20	R	H	-1.1777
21	L	H	0.0000
22	S	H	-0.1851
23	C	H	0.0000
24	A	H	-0.2485
25	A	H	0.0000
26	S	H	-0.9808
27	G	H	-0.9294
28	S	H	-0.1673
29	I	H	0.6348
30	F	H	2.1875
35	S	H	0.0000
36	I	H	0.0000
37	N	H	0.2132
38	A	H	0.0000
39	M	H	0.0000
40	H	H	0.3341
41	W	H	0.0000
42	F	H	0.4057
43	R	H	0.0000
44	Q	H	-1.0433
45	A	H	-1.1060
46	P	H	-0.9893
47	G	H	-1.3365
48	K	H	-1.9521
49	Q	H	-2.2649
50	R	H	-1.8210
51	E	H	-0.9222
52	L	H	0.4886
53	V	H	0.0000
54	A	H	0.0000
55	V	H	0.0000
56	I	H	0.0000
57	T	H	-0.3868
58	S	H	-0.6602
59	G	H	-0.8094
63	G	H	-0.9344
64	S	H	-0.1338
65	T	H	0.6994
66	I	H	1.6968
67	Y	H	0.2657
68	A	H	-0.7226
69	E	H	-2.2506
70	S	H	-1.7375
71	V	H	0.0000
72	K	H	-2.3049
74	G	H	-1.6944
75	R	H	-1.4019
76	F	H	0.0000
77	T	H	-0.4428
78	I	H	0.0000
79	S	H	-0.5143
80	R	H	-1.3231
81	D	H	-1.9711
82	N	H	-2.4621
83	S	H	-1.9855
84	K	H	-2.7021
85	N	H	-2.1085
86	T	H	-1.2602
87	V	H	0.0000
88	Y	H	-0.3485
89	L	H	0.0000
90	Q	H	-0.7783
91	M	H	0.0000
92	N	H	-1.1333
93	S	H	-1.1778
94	L	H	0.0000
95	R	H	-2.2808
96	P	H	-1.8903
97	E	H	-2.3226
98	D	H	0.0000
99	T	H	-0.4613
100	A	H	0.0000
101	V	H	0.5961
102	Y	H	0.0000
103	Y	H	0.5541
104	C	H	0.0000
105	N	H	0.0000
106	A	H	0.0000
107	H	H	-0.3868
108	V	H	0.3718
109	G	H	0.0000
110	L	H	0.8614
111	K	H	0.2262
111A	V	H	1.3303
111B	P	H	0.6374
111C	T	H	0.5962
112D	I	H	1.2385
112C	Q	H	0.4184
112B	E	H	0.5821
112A	L	H	1.6459
112	S	H	1.1423
113	L	H	1.7204
114	G	H	0.3547
115	F	H	1.0339
116	G	H	-0.0381
117	S	H	0.0000
118	W	H	0.9665
119	G	H	0.1418
120	Q	H	-0.4215
121	G	H	0.2841
122	T	H	0.5548
123	L	H	1.5718
124	V	H	0.0000
125	T	H	0.3387
126	V	H	0.0000
127	S	H	-0.7113
128	S	H	-0.8839