Project name: 4d82d5bc6624679

Chain sequence(s)	A: FKFEKGH; C: FKFEKGH; B: FKFEKGH; E: FKFEKGH; D: FKFEKGH; G: FKFEKGH; F: FKFEKGH; I: FKFEKGH; H: FKFEKGH; K: FKFEKGH; J: FKFEKGH; M: FKFEKGH; L: FKFEKGH; O: FKFEKGH; N: FKFEKGH; Q: FKFEKGH; P: FKFEKGH; S: FKFEKGH; R: FKFEKGH; T: FKFEKGH
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,M,L,O,N,Q,P,S,R,T
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:13:47)
[INFO]       Main:     Simulation completed successfully.                                          (00:13:52)

• Minimal score value: -2.6173
• Maximal score value: 1.2166
• Average score: -1.1887
• Total score value: -166.4189

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	F	A	-1.0139
2	K	A	-1.5327
3	F	A	0.0000
4	E	A	-1.3719
5	K	A	-1.0781
6	G	A	-1.2586
7	H	A	-1.5411
1	F	B	-0.9684
2	K	B	-1.8346
3	F	B	0.0000
4	E	B	-1.8748
5	K	B	-1.2376
6	G	B	-1.4049
7	H	B	-1.5306
1	F	C	-0.9967
2	K	C	-1.6894
3	F	C	0.0000
4	E	C	-1.6530
5	K	C	-1.0730
6	G	C	-1.4044
7	H	C	-1.4139
1	F	D	-0.8493
2	K	D	-1.4952
3	F	D	0.0000
4	E	D	-1.5261
5	K	D	-1.3303
6	G	D	-1.4658
7	H	D	-1.4563
1	F	E	-0.8190
2	K	E	-1.6704
3	F	E	0.0000
4	E	E	-1.5717
5	K	E	-1.1357
6	G	E	-1.4534
7	H	E	-1.4475
1	F	F	-1.1669
2	K	F	-1.6899
3	F	F	0.0000
4	E	F	-1.1124
5	K	F	-0.4750
6	G	F	-0.9473
7	H	F	-1.2151
1	F	G	0.6526
2	K	G	-1.5315
3	F	G	-1.1455
4	E	G	-2.4605
5	K	G	-1.6787
6	G	G	-1.5756
7	H	G	-1.2697
1	F	H	1.0614
2	K	H	-0.6625
3	F	H	-0.6302
4	E	H	-1.8719
5	K	H	-1.7929
6	G	H	-1.7140
7	H	H	-1.4505
1	F	I	-0.7619
2	K	I	-1.9736
3	F	I	0.0000
4	E	I	-1.9297
5	K	I	-1.2628
6	G	I	-1.3630
7	H	I	-1.2317
1	F	J	-1.0732
2	K	J	-1.6403
3	F	J	0.0000
4	E	J	-1.6844
5	K	J	-1.1221
6	G	J	-1.2336
7	H	J	-1.2046
1	F	K	-0.5760
2	K	K	-1.7111
3	F	K	0.0000
4	E	K	-2.2690
5	K	K	-1.6155
6	G	K	-1.7038
7	H	K	-1.7034
1	F	L	-0.7330
2	K	L	-1.6932
3	F	L	0.0000
4	E	L	-2.0326
5	K	L	-1.5325
6	G	L	-1.6695
7	H	L	-1.6856
1	F	M	-0.6924
2	K	M	-1.6817
3	F	M	0.0000
4	E	M	-2.1237
5	K	M	-1.6947
6	G	M	-1.7100
7	H	M	-1.7382
1	F	N	-1.1273
2	K	N	-1.6420
3	F	N	0.0000
4	E	N	-1.6288
5	K	N	-1.0217
6	G	N	-1.2636
7	H	N	-1.4501
1	F	O	-0.6246
2	K	O	-1.5427
3	F	O	0.0000
4	E	O	-1.6517
5	K	O	-1.3868
6	G	O	-1.5974
7	H	O	-1.5736
1	F	P	-1.2154
2	K	P	-2.1820
3	F	P	0.0000
4	E	P	-1.7582
5	K	P	0.0000
6	G	P	-1.1741
7	H	P	-1.2134
1	F	Q	-0.9931
2	K	Q	-1.9170
3	F	Q	0.0000
4	E	Q	-1.9170
5	K	Q	-1.0740
6	G	Q	-1.3730
7	H	Q	-1.4052
1	F	R	-1.4799
2	K	R	-1.6984
3	F	R	0.0000
4	E	R	-0.8954
5	K	R	-0.3554
6	G	R	-0.9022
7	H	R	-1.2847
1	F	S	1.2166
2	K	S	-0.3190
3	F	S	-0.1011
4	E	S	-2.0909
5	K	S	-2.6173
6	G	S	-2.2107
7	H	S	-1.6539
1	F	T	-0.0362
2	K	T	-1.8980
3	F	T	-1.5351
4	E	T	-2.6081
5	K	T	-1.5460
6	G	T	-1.4809
7	H	T	-1.3684