Project name: 14_x11e6_i20e6_x4e7_i14e7

Chain sequence(s)	A: GPGPGAEKLRHLNEKRRFHNGPGPGLDKKQRFHNIRGRWTGPGPGNPAEKLRHLNEKRRFGPGPGSKISEYRHYCYSLYGGPGPGVYDFAFRDLAAYRFHNIAGHYAAYCYSLYGTTLAAYKTVLELTEVAAYLLCHEQLSDSEEENDGPGPGQSTHVDIRTLEDLLMGPGPGTPTLHEYMLDLQPETGPGPGLQDIVLHLEPQNEIPGPGPGRAHYNIVTFAAYTLQDIVLHLAAYLLMGTLGIVAAYLPARRAEPQAAY
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:47)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:49)

• Minimal score value: -4.7705
• Maximal score value: 3.1037
• Average score: -0.3112
• Total score value: -81.2325

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-0.6890
2	P	A	-0.8064
3	G	A	-0.9351
4	P	A	-0.7973
5	G	A	-1.1012
6	A	A	-1.5734
7	E	A	-2.3950
8	K	A	-2.1875
9	L	A	-0.8248
10	R	A	-1.5789
11	H	A	-1.2528
12	L	A	-0.4240
13	N	A	-2.0036
14	E	A	-3.5732
15	K	A	-4.1378
16	R	A	-3.6830
17	R	A	-2.6302
18	F	A	-0.2167
19	H	A	-1.4502
20	N	A	-1.6319
21	G	A	-1.3831
22	P	A	-1.1911
23	G	A	-0.9199
24	P	A	-0.7085
25	G	A	-0.3782
26	L	A	-0.2514
27	D	A	-2.3596
28	K	A	-3.3052
29	K	A	-3.7958
30	Q	A	-2.8749
31	R	A	-2.1224
32	F	A	0.1785
33	H	A	-0.5952
34	N	A	-0.7366
35	I	A	0.3549
36	R	A	-1.7693
37	G	A	-1.5809
38	R	A	-1.9226
39	W	A	0.0081
40	T	A	-0.2756
41	G	A	-0.6219
42	P	A	-0.7113
43	G	A	-0.9189
44	P	A	-1.0265
45	G	A	-1.3972
46	N	A	-1.6762
47	P	A	-1.3790
48	A	A	-1.6104
49	E	A	-2.3559
50	K	A	-2.1580
51	L	A	-0.7618
52	R	A	-1.5866
53	H	A	-1.1618
54	L	A	-0.3401
55	N	A	-1.9337
56	E	A	-3.5638
57	K	A	-4.0025
58	R	A	-3.5220
59	R	A	-2.5747
60	F	A	0.0119
61	G	A	-0.4899
62	P	A	-0.5583
63	G	A	-0.6841
64	P	A	-1.0559
65	G	A	-0.9678
66	S	A	-0.9711
67	K	A	-1.2566
68	I	A	0.2904
69	S	A	-1.0101
70	E	A	-1.7190
71	Y	A	0.0933
72	R	A	-1.0128
73	H	A	-0.4679
74	Y	A	1.2224
75	C	A	1.9252
76	Y	A	2.0328
77	S	A	1.5080
78	L	A	2.5846
79	Y	A	2.0780
80	G	A	0.3934
81	G	A	-0.2502
82	P	A	-0.8001
83	G	A	-0.8121
84	P	A	-0.1447
85	G	A	0.2820
86	V	A	1.8138
87	Y	A	1.5576
88	D	A	0.1234
89	F	A	1.4927
90	A	A	0.9028
91	F	A	1.4585
92	R	A	-0.5162
93	D	A	0.2188
94	L	A	1.1211
95	A	A	-0.0456
96	A	A	0.1202
97	Y	A	0.2125
98	R	A	-0.9919
99	F	A	0.3301
100	H	A	-0.3386
101	N	A	-0.9528
102	I	A	0.9118
103	A	A	0.5261
104	G	A	-0.4215
105	H	A	0.0214
106	Y	A	1.1491
107	A	A	0.8567
108	A	A	1.1344
109	Y	A	1.9643
110	C	A	0.0000
111	Y	A	2.1842
112	S	A	1.6055
113	L	A	2.2252
114	Y	A	2.2678
115	G	A	1.0771
116	T	A	1.1076
117	T	A	1.1023
118	L	A	1.5744
119	A	A	1.0425
120	A	A	0.0000
121	Y	A	0.6549
122	K	A	-0.8508
123	T	A	-0.5643
124	V	A	0.0384
125	L	A	-0.5706
126	E	A	-1.7169
127	L	A	0.0127
128	T	A	-0.2177
129	E	A	-0.6398
130	V	A	1.5685
131	A	A	1.4379
132	A	A	1.1178
133	Y	A	2.0340
134	L	A	2.0637
135	L	A	1.8133
136	C	A	1.1708
137	H	A	-0.4823
138	E	A	-1.7251
139	Q	A	-1.7055
140	L	A	-0.8205
141	S	A	-2.4348
142	D	A	-3.7676
143	S	A	-3.1156
144	E	A	-4.1515
145	E	A	-4.7705
146	E	A	-4.6652
147	N	A	-4.0982
148	D	A	-3.8088
149	G	A	-2.3439
150	P	A	-1.3457
151	G	A	-1.3850
152	P	A	-1.1206
153	G	A	-1.4007
154	Q	A	-1.8101
155	S	A	-1.0536
156	T	A	-0.7034
157	H	A	-0.4814
158	V	A	1.0276
159	D	A	-0.1602
160	I	A	0.5961
161	R	A	-1.5321
162	T	A	-0.4443
163	L	A	0.6448
164	E	A	-1.1361
165	D	A	-1.1692
166	L	A	1.1483
167	L	A	1.7557
168	M	A	1.0716
169	G	A	0.1962
170	P	A	-0.4168
171	G	A	-0.9388
172	P	A	-0.7983
173	G	A	-0.8193
174	T	A	-0.6481
175	P	A	-0.4436
176	T	A	0.0154
177	L	A	1.2389
178	H	A	-0.1551
179	E	A	-0.7851
180	Y	A	1.3416
181	M	A	1.6114
182	L	A	1.2485
183	D	A	-0.3563
184	L	A	0.7600
185	Q	A	-1.0931
186	P	A	-1.6315
187	E	A	-2.2423
188	T	A	-1.5034
189	G	A	-1.2856
190	P	A	-1.0191
191	G	A	-0.7682
192	P	A	-0.6220
193	G	A	-0.4463
194	L	A	0.4138
195	Q	A	-0.7651
196	D	A	-0.3743
197	I	A	2.2251
198	V	A	2.8258
199	L	A	2.4538
200	H	A	0.6868
201	L	A	0.5580
202	E	A	-1.7202
203	P	A	-1.9658
204	Q	A	-2.3387
205	N	A	-2.5586
206	E	A	-1.8984
207	I	A	0.3863
208	P	A	-0.2975
209	G	A	-0.5924
210	P	A	-0.9793
211	G	A	-1.3490
212	P	A	-1.2750
213	G	A	-1.7384
214	R	A	-2.3197
215	A	A	-1.2651
216	H	A	-0.9738
217	Y	A	0.8662
218	N	A	0.7561
219	I	A	2.7960
220	V	A	2.8724
221	T	A	2.0785
222	F	A	2.2767
223	A	A	1.6855
224	A	A	1.5691
225	Y	A	1.7555
226	T	A	1.1247
227	L	A	1.5137
228	Q	A	0.2730
229	D	A	-0.3548
230	I	A	0.9962
231	V	A	2.1608
232	L	A	1.5958
233	H	A	0.4975
234	L	A	1.4559
235	A	A	1.6860
236	A	A	1.6364
237	Y	A	1.9557
238	L	A	2.1928
239	L	A	2.5744
240	M	A	2.7296
241	G	A	2.0600
242	T	A	2.3246
243	L	A	3.1037
244	G	A	2.2330
245	I	A	3.0593
246	V	A	2.9840
247	A	A	1.9926
248	A	A	1.7189
249	Y	A	1.9604
250	L	A	0.9843
251	P	A	-0.6108
252	A	A	-1.0810
253	R	A	-2.6897
254	R	A	-3.1241
255	A	A	-2.4630
256	E	A	-3.2642
257	P	A	-2.1640
258	Q	A	-1.7523
259	A	A	-0.5121
260	A	A	0.3505
261	Y	A	1.1886