Project name: P2A4

Chain sequence(s)	H: EVQVVESGGGLVQSGGSLRLSCTASVNILGIQVMGWYRQAPGKYPEPVASIDSDGTTKYADFVKGRFTISRDNAKNTVDLQMNNLKPEDTAVYYCAADRGLGPSDQYWGQGTQVTVSA
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:01)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:02)

• Minimal score value: -2.8484
• Maximal score value: 1.1168
• Average score: -0.7807
• Total score value: -92.1198

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1554
2	V	H	-1.4685
3	Q	H	-1.3977
4	V	H	0.0000
5	V	H	0.1204
6	E	H	-0.3803
7	S	H	-0.8921
8	G	H	-1.2768
9	G	H	-0.6943
11	G	H	0.0645
12	L	H	1.1168
13	V	H	-0.0244
14	Q	H	-1.4312
15	S	H	-1.8652
16	G	H	-1.9173
17	G	H	-1.3222
18	S	H	-1.4021
19	L	H	-1.0143
20	R	H	-2.2286
21	L	H	0.0000
22	S	H	-0.8564
23	C	H	0.0000
24	T	H	-0.5349
25	A	H	0.0000
26	S	H	-0.7980
27	V	H	-0.5991
28	N	H	-1.0776
29	I	H	0.0000
30	L	H	0.5904
35	G	H	-0.3530
36	I	H	0.0000
37	Q	H	-1.2524
38	V	H	-1.0231
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	Y	H	0.2602
43	R	H	0.0000
44	Q	H	-0.3735
45	A	H	-0.7870
46	P	H	-0.6180
47	G	H	-0.9029
48	K	H	-0.9290
49	Y	H	0.4449
50	P	H	0.0243
51	E	H	-0.2997
52	P	H	-0.5684
53	V	H	0.0000
54	A	H	0.0000
55	S	H	0.0000
56	I	H	0.0000
57	D	H	-1.5244
58	S	H	-1.4308
59	D	H	-2.1926
63	G	H	-1.5851
64	T	H	-1.1199
65	T	H	-1.1354
66	K	H	-1.4982
67	Y	H	-0.8527
68	A	H	-1.1672
69	D	H	-1.9524
70	F	H	-1.1710
71	V	H	0.0000
72	K	H	-2.2480
74	G	H	-1.6975
75	R	H	-1.5069
76	F	H	0.0000
77	T	H	-0.7646
78	I	H	0.0000
79	S	H	-0.7228
80	R	H	-1.3143
81	D	H	-1.7868
82	N	H	-1.5039
83	A	H	-1.3075
84	K	H	-2.3325
85	N	H	-1.5663
86	T	H	-1.2569
87	V	H	0.0000
88	D	H	-1.1746
89	L	H	0.0000
90	Q	H	-1.3487
91	M	H	0.0000
92	N	H	-1.9673
93	N	H	-2.4062
94	L	H	0.0000
95	K	H	-2.8484
96	P	H	-1.9765
97	E	H	-2.3488
98	D	H	0.0000
99	T	H	-0.8530
100	A	H	0.0000
101	V	H	-0.1486
102	Y	H	0.0000
103	Y	H	-0.0164
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	D	H	-1.3889
108	R	H	-1.9411
109	G	H	-0.9285
110	L	H	0.5232
112	G	H	-0.3416
113	P	H	-0.7522
114	S	H	-1.2507
115	D	H	-2.1691
116	Q	H	-1.4459
117	Y	H	-0.9009
118	W	H	0.0444
119	G	H	-0.3303
120	Q	H	-1.1366
121	G	H	-0.5611
122	T	H	-0.6645
123	Q	H	-0.6976
124	V	H	0.0000
125	T	H	-0.2071
126	V	H	0.0000
127	S	H	-0.7439
128	A	H	-0.6793