Project name: 5233a519938b176

Chain sequence(s)	H: EVQLVESGGGEVQPGGSLKLSCVASGTDFSINFVRWYRQRPGKQREWVAGFTANGDTNYPDSMKGRFTISRDNAKNTVYLQINSLKSEDTAVYYCYMLDNWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	5 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:40)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:41)

• Minimal score value: -2.0225
• Maximal score value: 1.0585
• Average score: -0.4089
• Total score value: -45.3837

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.7807
2	V	H	-0.3262
3	Q	H	-1.1593
4	L	H	0.0000
5	V	H	1.0585
6	E	H	-0.0618
7	S	H	-0.3190
8	G	H	-0.4544
9	G	H	-0.3625
11	G	H	-0.6569
12	E	H	-1.8372
13	V	H	-0.3366
14	Q	H	-1.1834
15	P	H	-0.6336
16	G	H	-0.5386
17	G	H	-0.3072
18	S	H	-0.2649
19	L	H	0.0441
20	K	H	-1.3384
21	L	H	0.0000
22	S	H	0.0202
23	C	H	0.0000
24	V	H	0.9340
25	A	H	0.0000
26	S	H	-0.1465
27	G	H	-0.4823
28	T	H	-0.4262
29	D	H	-1.7942
30	F	H	0.0000
35	S	H	-0.0755
36	I	H	0.4791
37	N	H	-1.0547
38	F	H	0.1704
39	V	H	0.0000
40	R	H	-0.2057
41	W	H	0.0000
42	Y	H	0.2397
43	R	H	0.0000
44	Q	H	-0.5609
45	R	H	-0.5787
46	P	H	-0.4208
47	G	H	-0.8110
48	K	H	-1.9995
49	Q	H	-1.6267
50	R	H	-0.9901
51	E	H	-0.3433
52	W	H	0.2980
53	V	H	0.0000
54	A	H	0.0000
55	G	H	0.0000
56	F	H	0.2191
57	T	H	0.0889
58	A	H	-0.3361
59	N	H	-1.3146
63	G	H	-0.8102
64	D	H	-1.8422
65	T	H	-0.4622
66	N	H	-0.7485
67	Y	H	0.0556
68	P	H	-0.3598
69	D	H	-2.0225
70	S	H	-0.5291
71	M	H	0.0000
72	K	H	-1.9205
74	G	H	-0.8410
75	R	H	-0.6113
76	F	H	0.0000
77	T	H	-0.0259
78	I	H	0.0000
79	S	H	-0.1635
80	R	H	-0.2817
81	D	H	-0.6067
82	N	H	-1.3548
83	A	H	-0.4684
84	K	H	-1.7310
85	N	H	-0.7019
86	T	H	0.0000
87	V	H	0.0000
88	Y	H	0.3741
89	L	H	0.0000
90	Q	H	-0.6447
91	I	H	0.0000
92	N	H	-0.6866
93	S	H	-0.3380
94	L	H	0.0000
95	K	H	-1.5613
96	S	H	-0.6638
97	E	H	-1.8320
98	D	H	0.0000
99	T	H	-0.0139
100	A	H	0.0000
101	V	H	0.4967
102	Y	H	0.0000
103	Y	H	0.1244
104	C	H	0.0000
105	Y	H	0.1999
106	M	H	0.0000
107	L	H	0.6108
116	D	H	-1.6915
117	N	H	-0.6310
118	W	H	0.3210
119	G	H	0.0000
120	Q	H	-1.2237
121	G	H	-0.3406
122	T	H	-0.1447
123	Q	H	-0.5304
124	V	H	0.0000
125	T	H	-0.2437
126	V	H	0.0000
127	S	H	-0.1333
128	S	H	-0.2303