Project name: 525b08340674517

Chain sequence(s)	A: SIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITIIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCG
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:48)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:49)

• Minimal score value: -2.6286
• Maximal score value: 3.5841
• Average score: 0.4584
• Total score value: 61.8845

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
120	S	A	0.7072
121	I	A	1.6128
122	D	A	-0.4390
123	V	A	1.0728
124	K	A	-0.3920
125	Y	A	1.0196
126	I	A	1.1660
127	G	A	0.3476
128	V	A	1.0865
129	K	A	-1.0082
130	S	A	-0.1348
131	A	A	0.3619
132	Y	A	1.6692
133	V	A	1.7553
134	S	A	0.6775
135	Y	A	0.8796
136	D	A	-0.6818
137	V	A	0.4047
138	Q	A	-1.8410
139	K	A	-2.6286
140	R	A	-2.2029
141	T	A	0.1113
142	I	A	2.4474
143	Y	A	3.2414
144	L	A	2.7123
145	N	A	0.8940
146	I	A	1.7924
147	T	A	0.3077
148	N	A	-0.1154
149	T	A	0.0782
150	L	A	0.8626
151	N	A	-0.1160
152	I	A	0.3962
153	T	A	-0.9180
154	N	A	-1.8470
155	N	A	-2.1131
156	N	A	-1.2766
157	Y	A	1.0069
158	Y	A	1.8926
159	S	A	1.3027
160	V	A	1.2901
161	E	A	-1.0292
162	V	A	0.1657
163	E	A	-1.4980
164	N	A	-1.1923
165	I	A	0.4477
166	T	A	0.0371
167	A	A	0.1516
168	Q	A	0.1798
169	V	A	1.3978
170	Q	A	0.8700
171	F	A	1.2809
172	S	A	-0.1699
173	K	A	-0.7442
174	T	A	0.3930
175	V	A	2.1946
176	I	A	1.9181
177	G	A	-0.1709
178	K	A	-1.8155
179	A	A	-1.0838
180	R	A	-1.8303
181	L	A	-0.5369
182	N	A	-1.2693
183	N	A	-0.6909
184	I	A	1.8929
185	T	A	1.9766
186	I	A	3.5841
187	I	A	3.1832
188	G	A	1.6533
189	P	A	1.2828
190	L	A	1.0389
191	D	A	-0.6052
192	M	A	-0.2181
193	K	A	-1.8296
194	Q	A	-1.4335
195	I	A	-0.0096
196	D	A	-0.8067
197	Y	A	1.0843
198	T	A	1.0045
199	V	A	2.3610
200	P	A	1.3416
201	T	A	1.7802
202	V	A	2.8509
203	I	A	2.4239
204	A	A	0.1313
205	E	A	-1.6081
206	E	A	-2.0721
207	M	A	-0.1104
208	S	A	0.0850
209	Y	A	1.6832
210	M	A	1.5778
211	Y	A	1.6988
212	D	A	0.2479
213	F	A	1.7584
214	C	A	1.1195
215	T	A	1.5095
216	L	A	2.4794
217	I	A	3.1629
218	S	A	2.0048
219	I	A	2.2202
220	K	A	-0.0227
221	V	A	0.7841
222	H	A	-0.1943
223	N	A	-0.0772
224	I	A	1.7034
225	V	A	2.8030
226	L	A	2.9293
227	M	A	2.4074
228	M	A	0.9487
229	Q	A	0.4677
230	V	A	1.6307
231	T	A	1.2010
232	V	A	2.2948
233	T	A	0.7690
234	T	A	0.5148
235	T	A	0.7083
236	Y	A	1.4199
237	F	A	1.9025
238	G	A	0.2495
239	H	A	-1.3818
240	S	A	-1.5663
241	E	A	-2.1934
242	Q	A	-0.7706
243	I	A	0.8231
244	S	A	0.0111
245	Q	A	-1.3224
246	E	A	-2.1889
247	R	A	-2.1667
248	Y	A	-0.3265
249	Q	A	-0.5910
250	Y	A	0.9746
251	V	A	0.8143
252	D	A	-1.0973
253	C	A	0.1194
254	G	A	-0.5238