Project name: 526d4a94f3d46e9

Chain sequence(s)	H: IVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWFQQKPGQPPKLLIYWASLRESGVSDRFSGSGSGTDFTLTISGLQAEDVAVYYCQQYYSILWTFGQGTKVEIKSTKGPSVFPLAPCTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVES
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:46)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:48)

• Minimal score value: -3.0885
• Maximal score value: 3.3875
• Average score: -0.5056
• Total score value: -103.1472

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	I	H	1.6561
3	V	H	1.7588
4	M	H	0.0000
5	T	H	-0.7154
6	Q	H	0.0000
7	S	H	-1.5220
8	P	H	-1.5229
9	D	H	-2.6350
10	S	H	-1.6598
11	L	H	-0.9388
12	A	H	-0.5724
13	V	H	0.0000
14	S	H	-0.6735
15	L	H	0.2563
16	G	H	-0.9357
17	E	H	-2.0438
18	R	H	-2.5624
19	A	H	0.0000
20	T	H	-0.7225
21	I	H	0.0000
22	N	H	-2.0092
23	C	H	0.0000
24	K	H	-2.0195
25	S	H	0.0000
26	S	H	-0.4600
27	Q	H	-1.1401
28	S	H	-0.8922
29	V	H	0.0000
30	L	H	-0.2546
31	Y	H	-0.1512
32	S	H	-0.6975
33	S	H	-0.8927
34	N	H	-1.5293
35	N	H	-1.9147
36	K	H	-1.4123
37	N	H	-0.3949
38	Y	H	0.5134
39	L	H	0.0000
40	A	H	0.0000
41	W	H	0.0000
42	F	H	0.1500
43	Q	H	-0.5009
44	Q	H	-1.2320
45	K	H	-1.6612
46	P	H	-1.0820
47	G	H	-1.3045
48	Q	H	-1.7967
49	P	H	-1.2555
50	P	H	-1.0164
51	K	H	-1.0378
52	L	H	-0.1937
53	L	H	0.0000
54	I	H	0.0000
55	Y	H	0.7024
56	W	H	0.5453
57	A	H	0.0000
65	S	H	0.0747
66	L	H	0.6059
67	R	H	-1.0268
68	E	H	-0.8601
69	S	H	-0.7425
70	G	H	-1.0414
71	V	H	-1.0078
72	S	H	-1.3906
74	D	H	-2.2659
75	R	H	-1.6561
76	F	H	0.0000
77	S	H	-0.6963
78	G	H	0.0000
79	S	H	-0.6883
80	G	H	-1.2532
83	S	H	-1.3010
84	G	H	-1.1678
85	T	H	-1.7269
86	D	H	-2.8083
87	F	H	0.0000
88	T	H	-1.2116
89	L	H	0.0000
90	T	H	-0.7466
91	I	H	0.0000
92	S	H	-1.6958
93	G	H	-1.5111
94	L	H	0.0000
95	Q	H	-1.3044
96	A	H	-0.7756
97	E	H	-1.9738
98	D	H	0.0000
99	V	H	-0.8009
100	A	H	0.0000
101	V	H	-0.9491
102	Y	H	0.0000
103	Y	H	0.0412
104	C	H	0.0000
105	Q	H	0.9165
106	Q	H	0.0000
107	Y	H	2.0507
108	Y	H	1.4780
109	S	H	2.0371
114	I	H	3.1883
115	L	H	3.3875
116	W	H	3.0966
117	T	H	2.0835
118	F	H	1.4083
119	G	H	0.0000
120	Q	H	-1.0677
121	G	H	0.0000
122	T	H	0.0000
123	K	H	-2.0305
124	V	H	0.0000
125	E	H	-0.6093
126	I	H	-0.3878
127	K	H	-1.5303
128	S	H	-1.2443
129	T	H	-1.1576
130	K	H	-1.3222
131	G	H	-1.4270
132	P	H	-0.7862
133	S	H	-0.0794
134	V	H	0.0000
135	F	H	0.8420
136	P	H	-0.0395
137	L	H	0.6382
138	A	H	0.0079
139	P	H	-0.0209
140	C	H	0.5809
141	T	H	-0.2361
142	A	H	-0.1775
143	A	H	0.0783
144	L	H	0.0000
145	G	H	0.0000
146	C	H	0.0000
147	L	H	0.7157
148	V	H	0.0000
149	K	H	-0.2609
150	D	H	-0.7023
151	Y	H	0.0000
152	F	H	0.0000
153	P	H	-1.5458
154	E	H	-1.7282
155	P	H	-1.5876
156	V	H	-1.2600
157	T	H	-0.9863
158	V	H	-0.4216
159	S	H	-0.5289
160	W	H	0.0000
161	N	H	-0.9081
162	S	H	-0.6775
163	G	H	-0.5682
164	A	H	-0.2466
165	L	H	-0.0739
166	T	H	-0.3164
167	S	H	-0.3776
168	G	H	-0.4750
169	V	H	-0.0197
170	H	H	-0.5500
171	T	H	0.1891
172	F	H	0.8947
173	P	H	0.5180
174	A	H	0.8511
175	V	H	2.1312
176	L	H	1.3592
177	Q	H	0.3864
178	S	H	-0.0391
179	S	H	-0.2994
180	G	H	-0.1277
181	L	H	-0.2678
182	Y	H	0.0000
183	S	H	0.0000
184	L	H	0.0000
185	S	H	0.6430
186	S	H	0.0000
187	V	H	0.4999
188	V	H	0.0000
189	T	H	-0.2117
190	V	H	0.0000
191	P	H	-0.5388
192	S	H	-0.3923
193	S	H	-0.5784
194	S	H	-0.7592
195	L	H	-0.8727
196	G	H	-1.0766
197	T	H	-1.0463
198	K	H	-1.8282
199	T	H	-1.5761
200	Y	H	0.0000
201	T	H	-1.6788
202	C	H	0.0000
203	N	H	-1.6880
204	V	H	0.0000
205	D	H	-2.6849
206	H	H	0.0000
207	K	H	-3.0885
208	P	H	-1.9430
209	S	H	-2.0093
210	N	H	-2.5135
211	T	H	-2.1360
212	K	H	-2.8218
213	V	H	-1.5475
214	D	H	-2.3419
215	K	H	-1.9355
216	R	H	-2.7560
217	V	H	0.0000
218	E	H	-2.4046
219	S	H	-0.9639