Project name: 5516a409ac4eb74

Chain sequence(s)	H: EVQLVESGGGVVQPGGSLKLSCVASGTDFSINFIRWYRQAPGKQREFVAGFTATGNTNYADSMKGRFTISRDNTKNAVYLQIDSLKPEDTAVYYCYMLDKWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:44)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:44)

• Minimal score value: -3.0997
• Maximal score value: 2.3815
• Average score: -0.8167
• Total score value: -90.6549

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.2964
2	V	H	-1.8910
3	Q	H	-1.4165
4	L	H	0.0000
5	V	H	1.3011
6	E	H	0.2933
7	S	H	-0.5455
8	G	H	-1.1622
9	G	H	-0.7697
10	G	H	0.2624
11	V	H	1.2826
12	V	H	0.1379
13	Q	H	-1.2249
14	P	H	-1.4612
15	G	H	-1.3582
16	G	H	-0.8749
17	S	H	-1.2791
18	L	H	-0.8976
19	K	H	-1.9573
20	L	H	0.0000
21	S	H	-0.1955
22	C	H	0.0000
23	V	H	0.2081
24	A	H	0.0000
25	S	H	-1.2281
26	G	H	-1.7719
27	T	H	-1.3683
28	D	H	-1.5817
29	F	H	0.0000
30	S	H	-0.0207
31	I	H	1.8209
32	N	H	0.0000
33	F	H	2.3815
34	I	H	0.0000
35	R	H	-0.2046
36	W	H	0.0000
37	Y	H	-0.6434
38	R	H	-1.2466
39	Q	H	-2.0229
40	A	H	-1.8645
41	P	H	-1.3543
42	G	H	-1.8469
43	K	H	-3.0997
44	Q	H	-3.0215
45	R	H	-2.6492
46	E	H	-1.9630
47	F	H	-0.7084
48	V	H	0.0000
49	A	H	0.0000
50	G	H	0.0000
51	F	H	-0.3540
52	T	H	-0.4349
53	A	H	0.2785
54	T	H	-0.6134
55	G	H	-0.6743
56	N	H	-1.6631
57	T	H	-1.0778
58	N	H	-1.5751
59	Y	H	-1.2655
60	A	H	-1.4285
61	D	H	-2.5197
62	S	H	-1.6452
63	M	H	0.0000
64	K	H	-2.7110
65	G	H	-1.8553
66	R	H	-1.5524
67	F	H	0.0000
68	T	H	-0.9898
69	I	H	0.0000
70	S	H	-0.6364
71	R	H	-1.4662
72	D	H	-2.2293
73	N	H	-2.5953
74	T	H	-1.9017
75	K	H	-2.5101
76	N	H	-2.0686
77	A	H	0.0000
78	V	H	0.0000
79	Y	H	-0.5692
80	L	H	0.0000
81	Q	H	-1.1826
82	I	H	0.0000
83	D	H	-1.6846
84	S	H	-1.3258
85	L	H	0.0000
86	K	H	-2.0401
87	P	H	-1.7698
88	E	H	-2.2003
89	D	H	0.0000
90	T	H	-0.8679
91	A	H	0.0000
92	V	H	-0.7183
93	Y	H	0.0000
94	Y	H	-0.3435
95	C	H	0.0000
96	Y	H	-0.2431
97	M	H	0.0000
98	L	H	0.2942
99	D	H	-1.4921
100	K	H	-1.5215
101	W	H	-0.4674
102	G	H	-0.1601
103	Q	H	-1.0428
104	G	H	-0.5474
105	T	H	0.0000
106	Q	H	-1.1999
107	V	H	0.0000
108	T	H	-0.2069
109	V	H	0.0000
110	S	H	-0.7855
111	S	H	-0.8533