Project name: 5675563cfcd9089

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGSGAANNPMGWFRQAPGKGRELVAAIGGAGSTSTYYPDSVEGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAARGSSSVSSGGGVNKEYATDPSYYSFWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:39)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:40)

• Minimal score value: -2.9044
• Maximal score value: 1.0578
• Average score: -0.7609
• Total score value: -102.72

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.0788
2	V	A	-1.2811
3	Q	A	-1.0980
4	L	A	0.0000
5	V	A	1.0578
6	E	A	0.0000
7	S	A	-0.4436
8	G	A	-1.0861
9	G	A	-0.7557
10	G	A	-0.0574
11	L	A	0.9145
12	V	A	0.0000
13	Q	A	-1.4977
14	P	A	-1.7553
15	G	A	-1.5041
16	G	A	-1.0128
17	S	A	-1.0151
18	L	A	-0.7585
19	R	A	-1.8317
20	L	A	0.0000
21	S	A	-0.3027
22	C	A	0.0000
23	A	A	-0.1814
24	A	A	0.0000
25	S	A	-1.0423
26	G	A	-1.3735
27	S	A	-0.8432
28	G	A	-1.1190
29	A	A	0.0000
30	A	A	-1.5671
31	N	A	-1.6072
32	N	A	0.0000
33	P	A	0.0000
34	M	A	0.0000
35	G	A	0.0000
36	W	A	0.0000
37	F	A	0.0000
38	R	A	0.0000
39	Q	A	-1.7234
40	A	A	-1.6080
41	P	A	-1.1721
42	G	A	-1.6580
43	K	A	-2.7265
44	G	A	-2.3139
45	R	A	-2.3742
46	E	A	-2.4840
47	L	A	0.0000
48	V	A	0.0000
49	A	A	0.0000
50	A	A	0.0000
51	I	A	0.0000
52	G	A	0.0000
53	G	A	0.0000
54	A	A	-1.0156
55	G	A	-0.8785
56	S	A	-0.5899
57	T	A	-0.3067
58	S	A	-0.3900
59	T	A	-0.3729
60	Y	A	-0.9138
61	Y	A	-1.3326
62	P	A	-1.8244
63	D	A	-2.5664
64	S	A	-1.8278
65	V	A	0.0000
66	E	A	-2.6801
67	G	A	-1.7447
68	R	A	0.0000
69	F	A	0.0000
70	T	A	-0.7892
71	I	A	0.0000
72	S	A	-0.4433
73	R	A	-1.1633
74	D	A	-1.8712
75	N	A	-2.1109
76	A	A	-1.6110
77	K	A	-2.6156
78	R	A	-2.5095
79	M	A	-1.2105
80	V	A	0.0000
81	Y	A	-0.5548
82	L	A	0.0000
83	Q	A	-1.0911
84	M	A	0.0000
85	N	A	-1.2894
86	S	A	-1.2189
87	L	A	0.0000
88	R	A	-2.6155
89	A	A	-1.8997
90	E	A	-2.3472
91	D	A	0.0000
92	T	A	-0.8955
93	A	A	0.0000
94	V	A	-0.4293
95	Y	A	0.0000
96	Y	A	-0.3025
97	C	A	0.0000
98	A	A	0.0000
99	A	A	0.0000
100	R	A	0.0000
101	G	A	-0.2943
102	S	A	-0.4307
103	S	A	-0.2022
104	S	A	0.1353
105	V	A	0.2369
106	S	A	-0.0070
107	S	A	-0.3775
108	G	A	-0.6279
109	G	A	0.0000
110	G	A	-0.4908
111	V	A	-1.0286
112	N	A	-2.3522
113	K	A	-2.8793
114	E	A	-2.9044
115	Y	A	-1.5356
116	A	A	0.0000
117	T	A	-1.6750
118	D	A	-1.5009
119	P	A	-0.7222
120	S	A	-0.2018
121	Y	A	0.4365
122	Y	A	0.0000
123	S	A	0.1473
124	F	A	0.1045
125	W	A	0.2419
126	G	A	-0.0496
127	Q	A	-0.7421
128	G	A	-0.5357
129	T	A	-0.7091
130	Q	A	-0.9842
131	V	A	0.0000
132	T	A	-0.3836
133	V	A	0.0000
134	S	A	-0.8876
135	S	A	-0.7882