Project name: KFDV_prM

Chain sequence(s)	A: ATVRRERTGNMVIRAEGKDAATQVEVMNGTCTILATDMGSWCDDSIMYECVTIDSGEEPVDVDCFCKGVERVSLEYGRCGKPAGGRNRRSVSIPVHAHSDLTGRGHKWLKGDSVKTHLTRVEGWVWKNKFLTAAFCAVVWMVTDSLPTRFIVITVALCLAPTYA
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:35)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:36)

• Minimal score value: -3.7312
• Maximal score value: 3.7226
• Average score: -0.4906
• Total score value: -80.4575

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-0.8568
2	T	A	-0.7167
3	V	A	-1.0983
4	R	A	-3.1416
5	R	A	-3.7232
6	E	A	-3.5585
7	R	A	-3.1482
8	T	A	-1.7944
9	G	A	-2.2456
10	N	A	-2.8936
11	M	A	0.0000
12	V	A	0.0000
13	I	A	0.0000
14	R	A	-1.0888
15	A	A	0.0000
16	E	A	-1.3452
17	G	A	-1.7244
18	K	A	-2.0035
19	D	A	-1.3576
20	A	A	-0.9643
21	A	A	-0.4700
22	T	A	-0.7444
23	Q	A	-1.5549
24	V	A	0.0000
25	E	A	-2.1013
26	V	A	0.0000
27	M	A	-0.0502
28	N	A	-1.3668
29	G	A	-1.5548
30	T	A	-1.5135
31	C	A	0.0000
32	T	A	-0.9180
33	I	A	0.0000
34	L	A	-0.3453
35	A	A	0.0000
36	T	A	-0.5673
37	D	A	-1.3440
38	M	A	0.0000
39	G	A	0.0000
40	S	A	-0.8954
41	W	A	-0.4792
42	C	A	-0.8869
43	D	A	-2.0205
44	D	A	-1.6107
45	S	A	-0.7041
46	I	A	0.3449
47	M	A	0.6071
48	Y	A	-0.1875
49	E	A	-2.1551
50	C	A	0.0000
51	V	A	-0.5380
52	T	A	-1.6581
53	I	A	0.0000
54	D	A	-3.2296
55	S	A	-2.3753
56	G	A	-2.4374
57	E	A	-3.4720
58	E	A	-2.8676
59	P	A	-1.1924
60	V	A	0.1094
61	D	A	-1.2114
62	V	A	-0.4241
63	D	A	-1.5087
64	C	A	0.0000
65	F	A	0.0000
66	C	A	0.0000
67	K	A	-2.3015
68	G	A	-1.8063
69	V	A	0.0000
70	E	A	-3.0772
71	R	A	-3.1119
72	V	A	0.0000
73	S	A	0.0000
74	L	A	0.0000
75	E	A	-0.1895
76	Y	A	0.0000
77	G	A	0.0000
78	R	A	-1.6019
79	C	A	-1.2664
80	G	A	-1.2045
81	K	A	-2.2392
82	P	A	-1.1354
83	A	A	-1.0969
84	G	A	-1.5161
85	G	A	-2.4412
86	R	A	-3.5685
87	N	A	-3.7312
88	R	A	-3.6572
89	R	A	-3.0103
90	S	A	-0.7527
91	V	A	1.3417
92	S	A	1.5160
93	I	A	2.6175
94	P	A	1.4844
95	V	A	1.5606
96	H	A	-0.2105
97	A	A	-0.7877
98	H	A	-1.4396
99	S	A	-1.2293
100	D	A	-1.5131
101	L	A	-0.0105
102	T	A	-0.6706
103	G	A	-1.2601
104	R	A	-2.5571
105	G	A	-2.1396
106	H	A	-2.1053
107	K	A	-1.9498
108	W	A	0.3385
109	L	A	0.7432
110	K	A	-1.4743
111	G	A	-1.4659
112	D	A	-2.2467
113	S	A	-0.8571
114	V	A	0.1014
115	K	A	-1.9080
116	T	A	-1.3355
117	H	A	-1.1635
118	L	A	-0.7878
119	T	A	-1.5687
120	R	A	-2.2646
121	V	A	0.0000
122	E	A	-2.0944
123	G	A	-1.7007
124	W	A	-1.1960
125	V	A	-0.3517
126	W	A	-0.3781
127	K	A	-1.3309
128	N	A	-0.1545
129	K	A	0.0197
130	F	A	1.9122
131	L	A	1.7037
132	T	A	1.3375
133	A	A	1.3047
134	A	A	1.7070
135	F	A	2.0719
136	C	A	2.2414
137	A	A	2.0679
138	V	A	2.8851
139	V	A	0.0000
140	W	A	2.7624
141	M	A	2.5429
142	V	A	2.4791
143	T	A	1.0972
144	D	A	-0.9482
145	S	A	-0.1254
146	L	A	1.1007
147	P	A	1.1047
148	T	A	1.3525
149	R	A	2.1953
150	F	A	3.5703
151	I	A	3.7226
152	V	A	2.9913
153	I	A	2.6434
154	T	A	2.3601
155	V	A	2.7432
156	A	A	2.0041
157	L	A	1.2493
158	C	A	0.9872
159	L	A	1.6227
160	A	A	1.0310
161	P	A	0.0000
162	T	A	0.6672
163	Y	A	1.4870
164	A	A	0.7908