Project name: clone35

Chain sequence(s)	H: QVQLQESGPGLVKPSETLSLTCTVPRGSIRSYYWSWIRQPPRKGLEWIGYVHDGGRVTYNPSLTSRVTMSVDTSKDQFSLKLRSVTAADTAVYYCARQRGVREDYIFRYYGMDVWGPGTTVIVSS; L: DIQLTQSPSFLSASVGDRVTITCRASQTISKYLNWYQQKLGKAPQLLIYEASTLQSGVPSRFSGGGSGTDFSLTINSLQPDDFAVYYCQQSDTTPYTFGQGTKLDVR
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:58)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:59)

• Minimal score value: -2.9776
• Maximal score value: 1.7078
• Average score: -0.5208
• Total score value: -120.822

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.6927
2	V	H	-1.3210
3	Q	H	-1.5126
4	L	H	0.0000
5	Q	H	-1.1788
6	E	H	0.0000
7	S	H	-0.7212
8	G	H	-0.4736
9	P	H	0.1095
11	G	H	0.5848
12	L	H	1.2549
13	V	H	0.0000
14	K	H	-1.8405
15	P	H	-1.4216
16	S	H	-1.6439
17	E	H	-2.2922
18	T	H	-1.7612
19	L	H	0.0000
20	S	H	-0.9512
21	L	H	0.0000
22	T	H	-0.5849
23	C	H	0.0000
24	T	H	-1.0408
25	V	H	0.0000
26	P	H	-1.6683
27	R	H	-2.4703
28	G	H	-1.9174
29	S	H	-1.4677
30	I	H	0.0000
35	R	H	-1.6743
36	S	H	-0.8565
37	Y	H	-0.1365
38	Y	H	0.0000
39	W	H	0.0000
40	S	H	0.0000
41	W	H	0.0000
42	I	H	0.0000
43	R	H	0.0000
44	Q	H	-0.9685
45	P	H	-1.1031
46	P	H	-1.6400
47	R	H	-2.8344
48	K	H	-2.9776
49	G	H	-1.7936
50	L	H	0.0000
51	E	H	-0.6781
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	Y	H	0.0000
56	V	H	0.0000
57	H	H	-1.2193
58	D	H	-1.6490
59	G	H	-1.5711
63	G	H	-1.5992
64	R	H	-2.0517
65	V	H	-0.4733
66	T	H	-0.0268
67	Y	H	0.2415
68	N	H	0.0000
69	P	H	-0.5434
70	S	H	-0.4358
71	L	H	0.0000
72	T	H	-0.3434
74	S	H	-0.6077
75	R	H	-1.0604
76	V	H	0.0000
77	T	H	-0.5964
78	M	H	0.0000
79	S	H	-0.7254
80	V	H	-0.9949
81	D	H	-1.5854
82	T	H	-1.6119
83	S	H	-1.4881
84	K	H	-2.2578
85	D	H	-2.0342
86	Q	H	-1.5431
87	F	H	0.0000
88	S	H	-0.5740
89	L	H	0.0000
90	K	H	-1.4655
91	L	H	0.0000
92	R	H	-1.8223
93	S	H	-1.4895
94	V	H	0.0000
95	T	H	-0.5898
96	A	H	-0.0510
97	A	H	0.1599
98	D	H	0.0000
99	T	H	0.5861
100	A	H	0.0000
101	V	H	0.3388
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	R	H	-0.1900
107	Q	H	0.0000
108	R	H	0.0524
109	G	H	0.4606
110	V	H	0.7797
111	R	H	-0.7389
111A	E	H	-1.7380
111B	D	H	-1.2164
111C	Y	H	0.5404
112C	I	H	1.2071
112B	F	H	0.4795
112A	R	H	-0.1873
112	Y	H	-0.0093
113	Y	H	0.1468
114	G	H	0.0000
115	M	H	0.0000
116	D	H	-0.4108
117	V	H	-0.4038
118	W	H	0.0000
119	G	H	0.0000
120	P	H	-1.0250
121	G	H	-0.6634
122	T	H	-0.3153
123	T	H	0.3258
124	V	H	0.0000
125	I	H	1.2974
126	V	H	0.0000
127	S	H	-0.2266
128	S	H	-0.5963
1	D	L	-2.2452
2	I	L	0.0000
3	Q	L	-2.2459
4	L	L	0.0000
5	T	L	-1.3949
6	Q	L	0.0000
7	S	L	-0.3018
8	P	L	0.3553
9	S	L	0.5087
10	F	L	1.7078
11	L	L	0.7891
12	S	L	-0.0897
13	A	L	0.0000
14	S	L	-0.5803
15	V	L	0.2254
16	G	L	-0.6727
17	D	L	-1.4249
18	R	L	-2.2581
19	V	L	0.0000
20	T	L	-0.5789
21	I	L	0.0000
22	T	L	-0.8252
23	C	L	0.0000
24	R	L	-2.7240
25	A	L	0.0000
26	S	L	-1.8735
27	Q	L	-1.8482
28	T	L	-1.1904
29	I	L	0.0000
36	S	L	-1.0568
37	K	L	-1.5890
38	Y	L	-0.8173
39	L	L	0.0000
40	N	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	-0.6578
45	K	L	-0.6784
46	L	L	0.6763
47	G	L	-0.6857
48	K	L	-1.8838
49	A	L	0.0000
50	P	L	0.0000
51	Q	L	-1.5202
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	-0.1630
56	E	L	-0.7598
57	A	L	0.0000
65	S	L	-0.4444
66	T	L	-0.0966
67	L	L	0.1949
68	Q	L	-0.2301
69	S	L	-0.3597
70	G	L	-0.4726
71	V	L	-0.2488
72	P	L	-0.3010
74	S	L	-0.4299
75	R	L	-0.8333
76	F	L	0.0000
77	S	L	-0.3213
78	G	L	-0.3055
79	G	L	-0.8401
80	G	L	-1.2402
83	S	L	-1.3085
84	G	L	-1.2270
85	T	L	-1.7177
86	D	L	-2.1798
87	F	L	0.0000
88	S	L	-0.7614
89	L	L	0.0000
90	T	L	0.0000
91	I	L	0.0000
92	N	L	-1.6314
93	S	L	-1.2086
94	L	L	0.0000
95	Q	L	-1.0233
96	P	L	-0.9261
97	D	L	-1.6521
98	D	L	0.0000
99	F	L	0.2337
100	A	L	0.0000
101	V	L	0.4139
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	Q	L	0.0000
107	S	L	0.0000
108	D	L	-0.7332
109	T	L	-0.6110
114	T	L	-0.4048
115	P	L	0.0000
116	Y	L	-0.4038
117	T	L	-0.7551
118	F	L	0.0000
119	G	L	0.0000
120	Q	L	-1.4448
121	G	L	0.0000
122	T	L	0.0000
123	K	L	0.1663
124	L	L	0.0000
125	D	L	-0.0303
126	V	L	-0.2798
127	R	L	-1.4169