Project name: 5884de786e92e6d

Chain sequence(s)	C: QIVMTQSPFSMYATLGERVTITCKASQDIYSYLSWLQQKPGKSSLKTLIYRANRLITGVPSRFSGSGSGQDYSLTISSLEEYEDMGIYYCLQYDEFPYTFGGGTKLEMKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINNVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNR
Selected Chain(s)	C
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:02)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:02)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with C chain(s) selected             (00:00:02)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:02)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:02)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:30)
[INFO]       Main:     Simulation completed successfully.                                          (00:04:31)

• Minimal score value: -4.3209
• Maximal score value: 2.0059
• Average score: -0.7038
• Total score value: -148.5094

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	C	-0.5936
2	I	C	0.3560
3	V	C	1.5103
4	M	C	0.0000
5	T	C	0.1361
6	Q	C	-0.1480
7	S	C	0.1498
8	P	C	0.6843
9	F	C	1.6815
10	S	C	0.9587
11	M	C	0.7107
12	Y	C	0.5012
13	A	C	0.0000
14	T	C	-0.8840
15	L	C	-0.6648
16	G	C	-1.2994
17	E	C	-2.0721
18	R	C	-2.4544
19	V	C	0.0000
20	T	C	-0.5437
21	I	C	0.0000
22	T	C	-0.5382
23	C	C	0.0000
24	K	C	-1.9581
25	A	C	0.0000
26	S	C	-0.9753
27	Q	C	-1.8845
28	D	C	-1.8346
29	I	C	0.0000
30	Y	C	0.4000
31	S	C	-0.2135
32	Y	C	0.1407
33	L	C	0.0000
34	S	C	0.0000
35	W	C	0.0000
36	L	C	0.0000
37	Q	C	0.0000
38	Q	C	-0.9455
39	K	C	-1.7578
40	P	C	-1.7334
41	G	C	-1.6081
42	K	C	-2.2129
43	S	C	-1.1000
44	L	C	-0.1191
45	K	C	-1.0442
46	T	C	-0.0910
47	L	C	0.0000
48	I	C	0.0000
49	Y	C	-0.3218
50	R	C	-1.0286
51	A	C	0.0000
52	N	C	-2.2380
53	R	C	-2.2277
54	L	C	-0.8724
55	I	C	-0.0449
56	T	C	-0.2613
57	G	C	-0.3891
58	V	C	0.0000
59	P	C	-0.3630
60	S	C	-0.4361
61	R	C	-0.9006
62	F	C	0.0000
63	S	C	-0.9267
64	G	C	-1.2201
65	S	C	-1.4959
66	G	C	-1.3734
67	S	C	-1.2254
68	G	C	-1.3802
69	Q	C	-2.5168
70	D	C	-2.8276
71	Y	C	0.0000
72	S	C	-0.9652
73	L	C	0.0000
74	T	C	-0.6443
75	I	C	0.0000
76	S	C	-1.5342
77	S	C	-1.4577
78	L	C	0.0000
79	E	C	-1.6068
80	Y	C	-1.7777
81	E	C	-2.5500
82	D	C	0.0000
83	M	C	0.0000
84	G	C	0.0000
85	I	C	0.3507
86	Y	C	0.0000
87	Y	C	0.4274
88	C	C	0.0000
89	L	C	1.1983
90	Q	C	0.0000
91	Y	C	0.7110
92	D	C	-0.5849
93	E	C	-0.9243
94	F	C	1.1892
95	P	C	1.0901
96	Y	C	1.7888
97	T	C	1.5472
98	F	C	2.0059
99	G	C	0.0000
100	G	C	0.3594
101	G	C	0.3820
102	T	C	0.0000
103	K	C	0.2155
104	L	C	0.0000
105	E	C	-0.4020
106	M	C	0.0000
107	K	C	-1.4595
108	R	C	-1.5123
109	A	C	-1.3972
110	D	C	-2.4215
111	A	C	-1.3544
112	A	C	-0.8132
113	P	C	0.0000
114	T	C	-0.1646
115	V	C	0.2197
116	S	C	0.5116
117	I	C	0.9130
118	F	C	1.2219
119	P	C	0.0235
120	P	C	-0.4910
121	S	C	-0.8175
122	S	C	-1.2814
123	E	C	-2.1607
124	Q	C	-1.4860
125	L	C	-1.2040
126	T	C	-1.0061
127	S	C	-0.9312
128	G	C	-1.1894
129	G	C	-1.2236
130	A	C	0.0000
131	S	C	0.0072
132	V	C	0.0000
133	V	C	1.0136
134	C	C	0.0000
135	F	C	0.8046
136	L	C	0.0000
137	N	C	-0.5516
138	N	C	-1.2549
139	F	C	0.0000
140	Y	C	0.0000
141	P	C	-2.1029
142	K	C	-2.4187
143	D	C	-2.6832
144	I	C	-1.6495
145	N	C	-1.9624
146	V	C	-0.7857
147	K	C	-1.8362
148	W	C	0.0000
149	K	C	-2.3740
150	I	C	0.0000
151	D	C	-2.6788
152	G	C	-1.9821
153	S	C	-2.1402
154	E	C	-3.3424
155	R	C	-2.9979
156	Q	C	-2.6008
157	N	C	-1.9560
158	G	C	-0.6070
159	V	C	-0.0201
160	L	C	1.0086
161	N	C	0.2589
162	S	C	0.2538
163	W	C	0.1880
164	T	C	-0.6811
165	D	C	-1.5379
166	Q	C	0.0000
167	D	C	-2.2968
168	S	C	-2.3708
169	K	C	-2.5198
170	D	C	-1.6934
171	S	C	0.0000
172	T	C	0.0000
173	Y	C	0.0000
174	S	C	-0.6149
175	M	C	0.0000
176	S	C	0.4519
177	S	C	0.0000
178	T	C	0.7506
179	L	C	0.0000
180	T	C	-0.1155
181	L	C	0.0000
182	T	C	-1.6541
183	K	C	-2.6858
184	D	C	-3.7010
185	E	C	-3.3915
186	Y	C	0.0000
187	E	C	-4.3209
188	R	C	-4.2138
189	H	C	-3.7509
190	N	C	-3.5766
191	S	C	-2.3549
192	Y	C	0.0000
193	T	C	-1.1299
194	C	C	0.0000
195	E	C	-0.5039
196	A	C	0.0000
197	T	C	-1.1015
198	H	C	0.0000
199	K	C	-2.5416
200	T	C	-1.3560
201	S	C	-0.7313
202	T	C	-0.6107
203	S	C	-0.3923
204	P	C	-0.4287
205	I	C	0.4961
206	V	C	0.5287
207	K	C	-0.0765
208	S	C	-0.5350
209	F	C	-0.9787
210	N	C	-2.6255
211	R	C	-3.1337