Project name: 5b82bafc7473a0f

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGRTFSYNPMGWFRQAPGKGRELVAAISRTGGSTYYPDSVEGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAAGVRAEDGRVRTLPSEYTFWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:19)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:21)

• Minimal score value: -2.6553
• Maximal score value: 1.3527
• Average score: -0.6567
• Total score value: -84.0604

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.6277
2	V	H	0.0000
3	Q	H	-1.5445
4	L	H	0.0000
5	V	H	1.2141
6	E	H	0.0000
7	S	H	-0.4131
8	G	H	-1.0071
9	G	H	-0.5211
10	G	H	0.3303
11	L	H	1.1288
12	V	H	0.0527
13	Q	H	-1.2783
14	P	H	-1.2726
15	G	H	-1.2863
16	G	H	-0.8983
17	S	H	-1.0225
18	L	H	-0.5657
19	R	H	-1.4752
20	L	H	0.0000
21	S	H	-0.2011
22	C	H	0.0000
23	A	H	-0.1154
24	A	H	0.0000
25	S	H	-1.2188
26	G	H	-2.1399
27	R	H	-2.6388
28	T	H	-1.5984
29	F	H	-0.9006
30	S	H	-0.5610
31	Y	H	0.5497
32	N	H	-0.3886
33	P	H	0.0000
34	M	H	0.0000
35	G	H	0.0000
36	W	H	0.0000
37	F	H	0.0000
38	R	H	0.0000
39	Q	H	-1.5318
40	A	H	-1.5262
41	P	H	-1.0688
42	G	H	-1.5497
43	K	H	-2.6495
44	G	H	-2.1489
45	R	H	-1.9626
46	E	H	-1.6152
47	L	H	-0.2736
48	V	H	0.0000
49	A	H	0.0000
50	A	H	0.0000
51	I	H	0.0000
52	S	H	0.0000
53	R	H	-1.0074
54	T	H	-0.7339
55	G	H	-0.8341
56	G	H	-0.9271
57	S	H	-0.7267
58	T	H	-0.1856
59	Y	H	0.1499
60	Y	H	-0.6640
61	P	H	-1.2924
62	D	H	-2.4566
63	S	H	-1.8243
64	V	H	0.0000
65	E	H	-2.6553
66	G	H	-1.8059
67	R	H	-1.5615
68	F	H	0.0000
69	T	H	-0.7300
70	I	H	0.0000
71	S	H	-0.3770
72	R	H	-0.8362
73	D	H	-1.2697
74	N	H	-1.2272
75	A	H	-1.2094
76	K	H	-2.3186
77	R	H	-1.7825
78	M	H	-0.7986
79	V	H	0.0000
80	Y	H	-0.3631
81	L	H	0.0000
82	Q	H	-0.9078
83	M	H	0.0000
84	N	H	-1.2106
85	S	H	-1.1273
86	L	H	0.0000
87	R	H	-1.9535
88	A	H	-1.5465
89	E	H	-2.1200
90	D	H	0.0000
91	T	H	-0.6857
92	A	H	0.0000
93	V	H	-0.2665
94	Y	H	0.0000
95	Y	H	-0.0858
96	C	H	0.0000
97	A	H	0.0000
98	A	H	0.0000
99	A	H	0.0000
100	G	H	-0.4152
101	V	H	0.3063
102	R	H	-1.7560
103	A	H	0.0000
104	E	H	-2.6109
105	D	H	-2.2392
106	G	H	-1.8316
107	R	H	-2.3291
108	V	H	-0.6922
109	R	H	-0.3152
110	T	H	0.7057
111	L	H	1.3527
112	P	H	0.1727
113	S	H	0.3805
114	E	H	0.0000
115	Y	H	0.0000
116	T	H	0.1311
117	F	H	0.1415
118	W	H	0.3067
119	G	H	-0.0057
120	Q	H	-0.7807
121	G	H	-0.3062
122	T	H	-0.4355
123	Q	H	-0.5016
124	V	H	0.0000
125	T	H	-0.0880
126	V	H	0.0000
127	S	H	-0.6992
128	S	H	-0.4847