Project name: 10_i14e7_x11e6_x4e7_i20e6

Chain sequence(s)	A: AAYRAHYNIVTFAAYTLQDIVLHLAAYLLMGTLGIVAAYLPARRAEPQAAYAEKLRHLNEKRRFHNGPGPGLDKKQRFHNIRGRWTGPGPGNPAEKLRHLNEKRRFGPGPGSKISEYRHYCYSLYGGPGPGLLCHEQLSDSEEENDGPGPGQSTHVDIRTLEDLLMGPGPGTPTLHEYMLDLQPETGPGPGLQDIVLHLEPQNEIPGPGPGVYDFAFRDLAAYRFHNIAGHYAAYCYSLYGTTLAAYKTVLELTEVAAY
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:49)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:51)

• Minimal score value: -4.558
• Maximal score value: 3.7525
• Average score: -0.2296
• Total score value: -59.469

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-0.2673
2	A	A	-0.0069
3	Y	A	0.2002
4	R	A	-1.0159
5	A	A	-0.0326
6	H	A	0.5648
7	Y	A	1.6325
8	N	A	1.3060
9	I	A	2.9574
10	V	A	3.3741
11	T	A	2.8158
12	F	A	3.6099
13	A	A	2.6249
14	A	A	1.9693
15	Y	A	2.2577
16	T	A	1.7235
17	L	A	2.3821
18	Q	A	1.0773
19	D	A	0.4013
20	I	A	2.3943
21	V	A	3.2211
22	L	A	2.5931
23	H	A	1.7730
24	L	A	3.3519
25	A	A	2.9762
26	A	A	2.8865
27	Y	A	3.6437
28	L	A	3.7189
29	L	A	3.7525
30	M	A	3.5231
31	G	A	2.6235
32	T	A	2.9043
33	L	A	3.6335
34	G	A	2.5272
35	I	A	3.5965
36	V	A	3.4653
37	A	A	2.2044
38	A	A	1.8704
39	Y	A	1.9731
40	L	A	0.9471
41	P	A	-0.7278
42	A	A	-1.2569
43	R	A	-2.9052
44	R	A	-3.2773
45	A	A	-2.6478
46	E	A	-3.1952
47	P	A	-2.2630
48	Q	A	-2.3693
49	A	A	-1.5573
50	A	A	-1.1045
51	Y	A	-0.6380
52	A	A	-1.2931
53	E	A	-2.7827
54	K	A	-2.5280
55	L	A	-1.7398
56	R	A	-3.8166
57	H	A	-3.7953
58	L	A	-3.0346
59	N	A	-3.8447
60	E	A	-4.2306
61	K	A	-4.1368
62	R	A	-4.5580
63	R	A	-3.8112
64	F	A	-1.6248
65	H	A	-2.6598
66	N	A	-2.7305
67	G	A	-1.6115
68	P	A	-0.8121
69	G	A	-0.8105
70	P	A	-0.6905
71	G	A	-0.6760
72	L	A	-0.4026
73	D	A	-2.9662
74	K	A	-3.5039
75	K	A	-3.6603
76	Q	A	-3.4052
77	R	A	-2.9670
78	F	A	-0.4235
79	H	A	-1.3964
80	N	A	-1.1441
81	I	A	0.2288
82	R	A	-1.6758
83	G	A	-1.6147
84	R	A	-1.6699
85	W	A	-0.2359
86	T	A	-0.2828
87	G	A	-0.6982
88	P	A	-0.7408
89	G	A	-1.0779
90	P	A	-1.1492
91	G	A	-1.8351
92	N	A	-2.3625
93	P	A	-1.6948
94	A	A	-1.8139
95	E	A	-3.1930
96	K	A	-2.8377
97	L	A	-1.1130
98	R	A	-3.1209
99	H	A	-3.1093
100	L	A	-1.8425
101	N	A	-3.1669
102	E	A	-3.8855
103	K	A	-3.9088
104	R	A	-3.7085
105	R	A	-3.0415
106	F	A	-0.4239
107	G	A	-0.8184
108	P	A	-0.6147
109	G	A	-0.7750
110	P	A	-1.1059
111	G	A	-1.0502
112	S	A	-0.8880
113	K	A	-1.2523
114	I	A	0.6363
115	S	A	-0.4868
116	E	A	-1.5525
117	Y	A	-0.3688
118	R	A	-1.7686
119	H	A	-0.7642
120	Y	A	1.1818
121	C	A	1.6670
122	Y	A	2.3602
123	S	A	1.8076
124	L	A	2.3631
125	Y	A	1.8360
126	G	A	0.1748
127	G	A	-0.4996
128	P	A	-0.9123
129	G	A	-0.8053
130	P	A	-0.2579
131	G	A	0.5168
132	L	A	2.0354
133	L	A	2.0112
134	C	A	0.7115
135	H	A	-1.0415
136	E	A	-2.0959
137	Q	A	-1.7878
138	L	A	-0.2660
139	S	A	-1.1671
140	D	A	-2.4446
141	S	A	-2.5234
142	E	A	-4.0166
143	E	A	-4.3622
144	E	A	-4.3236
145	N	A	-3.8740
146	D	A	-3.3704
147	G	A	-2.0445
148	P	A	-1.2488
149	G	A	-1.2756
150	P	A	-1.1431
151	G	A	-1.3469
152	Q	A	-1.7794
153	S	A	-1.0344
154	T	A	-0.6542
155	H	A	-0.3754
156	V	A	1.2229
157	D	A	0.0352
158	I	A	0.8258
159	R	A	-1.3224
160	T	A	-0.2034
161	L	A	1.0108
162	E	A	-0.9722
163	D	A	-0.9442
164	L	A	1.2361
165	L	A	1.8148
166	M	A	1.1222
167	G	A	0.0093
168	P	A	-0.1956
169	G	A	-0.8501
170	P	A	-0.8477
171	G	A	-0.8308
172	T	A	-0.0273
173	P	A	-0.3834
174	T	A	-0.0668
175	L	A	0.9996
176	H	A	-0.2042
177	E	A	-0.8134
178	Y	A	1.2883
179	M	A	1.6183
180	L	A	1.1340
181	D	A	-0.3476
182	L	A	0.6831
183	Q	A	-1.1406
184	P	A	-1.5971
185	E	A	-2.1984
186	T	A	-1.5116
187	G	A	-1.1673
188	P	A	-0.8346
189	G	A	-0.7320
190	P	A	-0.5672
191	G	A	-0.4547
192	L	A	0.3882
193	Q	A	-0.7209
194	D	A	-0.3266
195	I	A	2.1706
196	V	A	2.7454
197	L	A	2.4527
198	H	A	0.7137
199	L	A	0.5783
200	E	A	-1.7215
201	P	A	-1.9485
202	Q	A	-2.3249
203	N	A	-2.5505
204	E	A	-1.8734
205	I	A	0.3994
206	P	A	-0.0704
207	G	A	-0.5787
208	P	A	-0.2764
209	G	A	-0.6284
210	P	A	-0.4813
211	G	A	0.0049
212	V	A	1.4696
213	Y	A	1.5184
214	D	A	-0.0778
215	F	A	1.5109
216	A	A	1.2611
217	F	A	1.5687
218	R	A	-0.7687
219	D	A	-1.0325
220	L	A	1.1824
221	A	A	0.2775
222	A	A	0.0708
223	Y	A	0.4754
224	R	A	-0.6983
225	F	A	0.6301
226	H	A	-0.7405
227	N	A	-0.7782
228	I	A	1.2068
229	A	A	0.6028
230	G	A	-0.2474
231	H	A	0.0668
232	Y	A	1.6906
233	A	A	1.2686
234	A	A	1.2417
235	Y	A	2.1622
236	C	A	2.0839
237	Y	A	2.5544
238	S	A	1.5719
239	L	A	2.2835
240	Y	A	2.4036
241	G	A	1.7073
242	T	A	1.1755
243	T	A	1.3855
244	L	A	2.2318
245	A	A	1.0310
246	A	A	1.2688
247	Y	A	1.7890
248	K	A	0.0076
249	T	A	0.6769
250	V	A	1.9293
251	L	A	0.7206
252	E	A	-0.6194
253	L	A	1.4383
254	T	A	0.5386
255	E	A	-0.3836
256	V	A	1.4677
257	A	A	0.9532
258	A	A	0.8393
259	Y	A	1.4891