Project name: 182

Chain sequence(s)	H: QVQLQESGGGSVQAGGSLRLSCAASGSTYSSNCMGWFRQAPGKEREEVASMSIRSGRTYYSDSVKGRFTISHDGSKNTLYLQMNGLKAEDTAMYYCAAAYGGSRCDYNYRGQGTPVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:44)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:45)

• Minimal score value: -3.2701
• Maximal score value: 1.1889
• Average score: -0.9483
• Total score value: -113.8001

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.6217
2	V	H	0.0000
3	Q	H	-2.2924
4	L	H	0.0000
5	Q	H	-2.0611
6	E	H	0.0000
7	S	H	-1.0989
8	G	H	-1.0268
9	G	H	-0.8517
11	G	H	-0.6514
12	S	H	-0.5207
13	V	H	-0.6827
14	Q	H	-1.5272
15	A	H	-1.5028
16	G	H	-1.2868
17	G	H	-1.0339
18	S	H	-1.0842
19	L	H	-0.9296
20	R	H	-1.7730
21	L	H	0.0000
22	S	H	-0.7655
23	C	H	0.0000
24	A	H	-1.0592
25	A	H	-1.1059
26	S	H	-1.3742
27	G	H	-1.0252
28	S	H	-0.4942
29	T	H	0.0266
30	Y	H	1.1889
35	S	H	0.3771
36	S	H	0.0000
37	N	H	-0.5161
38	C	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	-0.5131
43	R	H	0.0000
44	Q	H	-1.6192
45	A	H	-1.6372
46	P	H	-1.3014
47	G	H	-1.8522
48	K	H	-3.0319
49	E	H	-3.2701
50	R	H	-2.3433
51	E	H	-1.7024
52	E	H	-0.8570
53	V	H	0.0000
54	A	H	0.0000
55	S	H	0.0000
56	M	H	0.0000
57	S	H	-1.2217
58	I	H	-1.1483
59	R	H	-2.2466
62	S	H	-1.7786
63	G	H	-1.7955
64	R	H	-2.1489
65	T	H	-0.5365
66	Y	H	0.0989
67	Y	H	-0.3541
68	S	H	-1.1867
69	D	H	-2.3602
70	S	H	-1.7743
71	V	H	0.0000
72	K	H	-2.2384
74	G	H	-1.6445
75	R	H	-1.6276
76	F	H	0.0000
77	T	H	-0.6457
78	I	H	0.0000
79	S	H	-0.5156
80	H	H	-0.8629
81	D	H	-1.4468
82	G	H	-1.7338
83	S	H	-1.5563
84	K	H	-2.3681
85	N	H	-1.6729
86	T	H	-1.2378
87	L	H	0.0000
88	Y	H	-0.3959
89	L	H	0.0000
90	Q	H	-1.0377
91	M	H	0.0000
92	N	H	-1.3757
93	G	H	-1.2829
94	L	H	0.0000
95	K	H	-2.0133
96	A	H	-1.5270
97	E	H	-2.1491
98	D	H	0.0000
99	T	H	-0.8028
100	A	H	0.0000
101	M	H	-0.0901
102	Y	H	0.0000
103	Y	H	-0.8053
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	A	H	0.0000
108	Y	H	-0.4316
109	G	H	-1.3402
110	G	H	-1.3178
111	S	H	-1.5787
112	R	H	-2.4813
113	C	H	-1.8790
114	D	H	-2.6116
115	Y	H	-1.7657
116	N	H	-1.7565
117	Y	H	-1.6003
118	R	H	-2.6191
119	G	H	0.0000
120	Q	H	-2.0706
121	G	H	-1.0696
122	T	H	0.0000
123	P	H	-0.4904
124	V	H	0.0000
125	T	H	-0.6805
126	V	H	0.0000
127	S	H	-1.0275
128	S	H	-0.7766