Project name: 62e651af9f28016

Chain sequence(s)	D: EVQLVESGGGLVQPGGSLRLSCAASGSVPFSSFSSMGWFRQAPGKGRELVAYITSSSTYYADSVKGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAGYAAVFDYWGQGTQVTVSS
Selected Chain(s)	D
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with D chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:39)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:40)

• Minimal score value: -2.9812
• Maximal score value: 1.7283
• Average score: -0.7209
• Total score value: -84.3444

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	D	-2.0495
2	V	D	-1.4029
3	Q	D	-1.2424
4	L	D	0.0000
5	V	D	0.6377
6	E	D	-0.1800
7	S	D	-0.5777
8	G	D	-1.0523
9	G	D	-0.7984
10	G	D	-0.0352
11	L	D	0.9935
12	V	D	-0.0917
13	Q	D	-1.4434
14	P	D	-1.8989
15	G	D	-1.6762
16	G	D	-1.2172
17	S	D	-1.5676
18	L	D	-1.0162
19	R	D	-2.1465
20	L	D	0.0000
21	S	D	-0.4345
22	C	D	0.0000
23	A	D	-0.4793
24	A	D	0.0000
25	S	D	-0.9543
26	G	D	-1.3033
27	S	D	-0.9205
28	V	D	-0.4182
29	P	D	-0.6135
30	F	D	0.0000
31	S	D	-1.0175
32	S	D	-0.2412
33	F	D	0.0000
34	S	D	0.2324
35	S	D	0.0000
36	M	D	0.0000
37	G	D	0.0000
38	W	D	0.0000
39	F	D	-0.2074
40	R	D	0.0000
41	Q	D	-1.9391
42	A	D	-1.8749
43	P	D	-1.2592
44	G	D	-1.7261
45	K	D	-2.8533
46	G	D	-2.5634
47	R	D	-2.6895
48	E	D	-2.0198
49	L	D	-0.1552
50	V	D	0.0000
51	A	D	0.0000
52	Y	D	0.6273
53	I	D	0.2835
54	T	D	0.0451
55	S	D	-0.4139
56	S	D	-0.3426
57	S	D	-0.0073
58	T	D	0.3671
59	Y	D	0.5223
60	Y	D	-0.4158
61	A	D	-1.1381
62	D	D	-2.4076
63	S	D	-1.7748
64	V	D	0.0000
65	K	D	-2.5192
66	G	D	-1.8682
67	R	D	-1.8194
68	F	D	0.0000
69	T	D	-0.8720
70	I	D	0.0000
71	S	D	-0.4037
72	R	D	-1.2657
73	D	D	-2.0433
74	N	D	-2.6738
75	A	D	-2.0043
76	K	D	-2.9159
77	R	D	-2.9812
78	M	D	-1.5306
79	V	D	0.0000
80	Y	D	-0.5455
81	L	D	0.0000
82	Q	D	-1.5121
83	M	D	0.0000
84	N	D	-2.2170
85	S	D	-1.6746
86	L	D	0.0000
87	R	D	-2.9157
88	A	D	-1.9755
89	E	D	-2.4274
90	D	D	0.0000
91	T	D	-0.9671
92	A	D	0.0000
93	V	D	-0.6050
94	Y	D	0.0000
95	Y	D	-0.3154
96	C	D	0.0000
97	A	D	0.0000
98	A	D	0.0000
99	G	D	0.0000
100	Y	D	1.1195
101	A	D	1.0055
102	A	D	1.0455
103	V	D	1.7283
104	F	D	0.5975
105	D	D	-0.8262
106	Y	D	-0.3778
107	W	D	-0.0774
108	G	D	-0.2210
109	Q	D	-0.9791
110	G	D	-0.6132
111	T	D	-0.8140
112	Q	D	-1.0523
113	V	D	0.0000
114	T	D	-0.3798
115	V	D	0.0000
116	S	D	-0.8460
117	S	D	-0.7438