Project name: 6504f5aecdba5

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGFTISNYGMSWVRQAPGKGLEWVSAITVSGGRAYYADSVKGRFTISRDNAKNTVYLQMNSLRAEDTAVYYCARDRVVVAGIAFDYWGQGTLVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:04)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:05)

• Minimal score value: -2.557
• Maximal score value: 2.3763
• Average score: -0.4441
• Total score value: -53.7415

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	E	A	-2.1753
3	V	A	-1.2808
4	Q	A	-1.4315
5	L	A	0.0000
6	V	A	0.4209
7	E	A	0.0000
8	S	A	-0.2578
9	G	A	-0.6428
10	G	A	-0.0299
11	G	A	0.5648
12	L	A	1.2730
13	V	A	0.0000
14	Q	A	-1.3949
15	P	A	-1.7509
16	G	A	-1.4028
17	G	A	-0.9925
18	S	A	-1.2629
19	L	A	-0.9720
20	R	A	-1.9823
21	L	A	0.0000
22	S	A	-0.4625
23	C	A	0.0000
24	A	A	-0.3100
25	A	A	0.0000
26	S	A	-1.0202
27	G	A	-1.2875
28	F	A	-0.7422
29	T	A	-0.5808
30	I	A	0.0000
31	S	A	-0.9432
32	N	A	-0.6930
33	Y	A	0.1900
34	G	A	0.0000
35	M	A	0.0000
36	S	A	0.0000
37	W	A	0.0000
38	V	A	0.0000
39	R	A	0.0000
40	Q	A	-0.3939
41	A	A	-1.0274
42	P	A	-0.9941
43	G	A	-1.3980
44	K	A	-2.0834
45	G	A	-0.9343
46	L	A	0.4825
47	E	A	-0.3776
48	W	A	0.2878
49	V	A	0.0000
50	S	A	0.0000
51	A	A	0.0000
52	I	A	0.0000
53	T	A	0.0000
54	V	A	0.1527
55	S	A	-0.7945
56	G	A	-1.2401
57	G	A	-1.2941
58	R	A	-1.7596
59	A	A	-0.6898
60	Y	A	-0.1735
61	Y	A	-0.4858
62	A	A	-1.1394
63	D	A	-2.4004
64	S	A	-1.6047
65	V	A	0.0000
66	K	A	-2.5570
67	G	A	-1.7793
68	R	A	-1.4013
69	F	A	0.0000
70	T	A	-0.7553
71	I	A	0.0000
72	S	A	-0.7127
73	R	A	-1.0845
74	D	A	-1.8363
75	N	A	-1.8043
76	A	A	-1.4257
77	K	A	-2.3634
78	N	A	-1.8059
79	T	A	-1.1312
80	V	A	0.0000
81	Y	A	-0.5425
82	L	A	0.0000
83	Q	A	-1.1824
84	M	A	0.0000
85	N	A	-1.4423
86	S	A	-1.2709
87	L	A	0.0000
88	R	A	-2.2750
89	A	A	-1.7262
90	E	A	-2.1962
91	D	A	0.0000
92	T	A	-0.5272
93	A	A	0.0000
94	V	A	0.6210
95	Y	A	0.0000
96	Y	A	0.4618
97	C	A	0.0000
98	A	A	0.0000
99	R	A	0.0000
100	D	A	0.0000
101	R	A	-0.1633
102	V	A	1.7151
103	V	A	2.3079
104	V	A	2.2656
105	A	A	1.6307
106	G	A	0.0000
107	I	A	2.3763
108	A	A	0.8736
109	F	A	0.8215
110	D	A	-0.1175
111	Y	A	0.3455
112	W	A	0.5478
113	G	A	-0.1372
114	Q	A	-0.8533
115	G	A	-0.0656
116	T	A	0.3299
117	L	A	1.1924
118	V	A	0.0000
119	T	A	0.2201
120	V	A	0.0000
121	S	A	-0.7615
122	S	A	-0.4980