Project name: 13.34E7

Chain sequence(s)	H: EVQLQQSGPELVKPGASVKISCRTSGYTFTDYYMNWVKRSHGKSLEWIGDIYPNNGVTTYNRKFKGKATLTVDKSSSTAYMELRSLTSEDSSVYYCAKTGDWTVGYFDVWGTGTTVTVSS; L: QIVLTQSPAIMSASPGEKVTISCSASSSVSYMYWYQQKPGSSPKPWIYRTSNLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCQQYHSYPRTFGGGTKLEIK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:45)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:46)

• Minimal score value: -3.3136
• Maximal score value: 1.4897
• Average score: -0.5292
• Total score value: -119.5944

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9975
2	V	H	-1.0388
3	Q	H	-2.0765
4	L	H	0.0000
5	Q	H	-2.2573
6	Q	H	0.0000
7	S	H	-1.1072
8	G	H	-0.7906
9	P	H	-0.4389
11	E	H	-0.4553
12	L	H	0.7839
13	V	H	-0.2872
14	K	H	-1.7070
15	P	H	-1.3963
16	G	H	-1.2198
17	A	H	-0.9725
18	S	H	-1.0781
19	V	H	-0.7993
20	K	H	-1.3696
21	I	H	0.0000
22	S	H	-0.9133
23	C	H	0.0000
24	R	H	-2.5017
25	T	H	0.0000
26	S	H	-1.5223
27	G	H	-1.1263
28	Y	H	-0.6143
29	T	H	-0.4430
30	F	H	0.0000
35	T	H	-1.2458
36	D	H	-1.2667
37	Y	H	0.0581
38	Y	H	0.7240
39	M	H	0.0000
40	N	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	K	H	0.0000
44	R	H	0.0000
45	S	H	-1.5227
46	H	H	-1.9194
47	G	H	-1.7801
48	K	H	-2.4343
49	S	H	-1.4114
50	L	H	0.0000
51	E	H	-1.0038
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	D	H	0.0000
56	I	H	0.0000
57	Y	H	0.1721
58	P	H	0.0000
59	N	H	-1.5860
62	N	H	-1.3862
63	G	H	-0.4086
64	V	H	0.8444
65	T	H	0.5539
66	T	H	0.0233
67	Y	H	-1.0948
68	N	H	0.0000
69	R	H	-3.3136
70	K	H	-3.2106
71	F	H	0.0000
72	K	H	-3.0598
74	G	H	-2.0239
75	K	H	-1.8190
76	A	H	0.0000
77	T	H	-0.7627
78	L	H	0.0000
79	T	H	0.0937
80	V	H	-0.5328
81	D	H	-1.3605
82	K	H	-1.9392
83	S	H	-1.0082
84	S	H	-1.0367
85	S	H	-1.2576
86	T	H	0.0000
87	A	H	0.0000
88	Y	H	-0.3590
89	M	H	0.0000
90	E	H	-0.9471
91	L	H	0.0000
92	R	H	-1.2336
93	S	H	-1.0663
94	L	H	0.0000
95	T	H	-1.2671
96	S	H	-1.4454
97	E	H	-2.0661
98	D	H	0.0000
99	S	H	-0.7271
100	S	H	0.0000
101	V	H	0.0207
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	K	H	0.0000
107	T	H	0.2335
108	G	H	0.1562
109	D	H	0.0616
110	W	H	0.9051
111	T	H	0.3868
112	V	H	0.0000
113	G	H	0.0000
114	Y	H	0.1599
115	F	H	0.0000
116	D	H	-0.4945
117	V	H	-0.3114
118	W	H	0.0000
119	G	H	0.0000
120	T	H	-0.5888
121	G	H	-0.3565
122	T	H	0.0000
123	T	H	-0.0909
124	V	H	0.0000
125	T	H	-0.2153
126	V	H	0.0000
127	S	H	-0.6017
128	S	H	-0.7465
1	Q	L	-0.9131
2	I	L	0.0000
3	V	L	1.2325
4	L	L	0.0000
5	T	L	0.0743
6	Q	L	0.0000
7	S	L	-0.0879
8	P	L	0.2841
9	A	L	0.6249
10	I	L	1.4897
11	M	L	0.4273
12	S	L	-0.7325
13	A	L	0.0000
14	S	L	-1.7576
15	P	L	-1.8849
16	G	L	-1.9653
17	E	L	-2.8653
18	K	L	-2.7350
19	V	L	0.0000
20	T	L	-0.6946
21	I	L	0.0000
22	S	L	-0.3481
23	C	L	0.0000
24	S	L	-0.1952
25	A	L	0.0000
26	S	L	0.0380
27	S	L	-0.2677
28	S	L	-0.5965
29	V	L	0.0000
37	S	L	-0.3411
38	Y	L	0.0369
39	M	L	0.0000
40	Y	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	-1.0986
45	K	L	-1.3797
46	P	L	-0.8117
47	G	L	-0.8151
48	S	L	-0.8947
49	S	L	-0.7423
50	P	L	0.0000
51	K	L	-1.8033
52	P	L	0.0000
53	W	L	-0.4600
54	I	L	0.0000
55	Y	L	-0.2295
56	R	L	-0.5467
57	T	L	0.0000
65	S	L	-0.7492
66	N	L	-1.0824
67	L	L	-0.2193
68	A	L	0.0000
69	S	L	-0.4286
70	G	L	-0.4025
71	V	L	-0.1277
72	P	L	-0.0835
74	A	L	-0.0623
75	R	L	-0.6412
76	F	L	0.0000
77	S	L	-0.4190
78	G	L	-0.5219
79	S	L	-0.6405
80	G	L	-0.5992
83	S	L	-0.5438
84	G	L	-0.5457
85	T	L	-0.5273
86	S	L	-0.6383
87	Y	L	0.0000
88	S	L	-0.3912
89	L	L	0.0000
90	T	L	-0.5916
91	I	L	0.0000
92	S	L	-1.4313
93	S	L	-1.8254
94	M	L	0.0000
95	E	L	-2.2985
96	A	L	-1.6617
97	E	L	-2.2487
98	D	L	0.0000
99	A	L	-1.4560
100	A	L	0.0000
101	T	L	-0.5427
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	Q	L	0.0000
107	Y	L	-0.0444
108	H	L	-0.6391
109	S	L	-0.4939
114	Y	L	-0.2024
115	P	L	0.0000
116	R	L	-0.2193
117	T	L	0.0000
118	F	L	0.0000
119	G	L	0.0000
120	G	L	-0.7395
121	G	L	0.0000
122	T	L	0.0000
123	K	L	-0.4491
124	L	L	0.0000
125	E	L	-1.4318
126	I	L	-1.0897
127	K	L	-1.8097