Project name: 6556cebfc8c81b4

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGTGYSNPMGWFRQAPGKGRELVAAIEGSSTYYPDSVEGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAYAHKLPSRISFDKFFEAAAKDPSVFAFWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:04)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:05)

• Minimal score value: -2.8841
• Maximal score value: 0.8639
• Average score: -0.9128
• Total score value: -121.396

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.1448
2	V	A	0.0000
3	Q	A	-1.4799
4	L	A	0.0000
5	V	A	0.5179
6	E	A	0.0000
7	S	A	-0.6945
8	G	A	-0.9754
9	G	A	-0.7998
10	G	A	-0.0996
11	L	A	0.8639
12	V	A	0.0000
13	Q	A	-1.4545
14	P	A	-1.6480
15	G	A	-1.3993
16	G	A	-0.9477
17	S	A	-1.1332
18	L	A	-0.9775
19	R	A	-2.2680
20	L	A	0.0000
21	S	A	-0.5059
22	C	A	0.0000
23	A	A	-0.2548
24	A	A	0.0000
25	S	A	-1.0662
26	G	A	-1.2238
27	T	A	-0.8463
28	G	A	-0.9595
29	Y	A	-0.7093
30	S	A	-0.9964
31	N	A	0.0000
32	P	A	0.0000
33	M	A	0.0000
34	G	A	0.0000
35	W	A	0.0000
36	F	A	0.0000
37	R	A	0.0000
38	Q	A	-1.5715
39	A	A	-1.5593
40	P	A	-1.1769
41	G	A	-1.6446
42	K	A	-2.6287
43	G	A	-2.2852
44	R	A	-2.2507
45	E	A	-2.1055
46	L	A	0.0000
47	V	A	0.0000
48	A	A	0.0000
49	A	A	0.0000
50	I	A	0.0000
51	E	A	-0.9611
52	G	A	-0.9362
53	S	A	-0.6422
54	S	A	-0.6344
55	T	A	-0.3965
56	Y	A	-0.9772
57	Y	A	-1.2600
58	P	A	-1.6718
59	D	A	-2.5608
60	S	A	-1.8076
61	V	A	0.0000
62	E	A	-2.7172
63	G	A	-1.8125
64	R	A	-1.5345
65	F	A	0.0000
66	T	A	-0.9856
67	I	A	0.0000
68	S	A	-0.6550
69	R	A	-1.4129
70	D	A	-2.0513
71	N	A	-2.3016
72	A	A	-1.7767
73	K	A	-2.6473
74	R	A	-2.2667
75	M	A	-1.2553
76	V	A	0.0000
77	Y	A	-0.7341
78	L	A	0.0000
79	Q	A	-1.6249
80	M	A	0.0000
81	N	A	-1.3512
82	S	A	-1.1304
83	L	A	0.0000
84	R	A	-2.2629
85	A	A	-1.7323
86	E	A	-2.2300
87	D	A	0.0000
88	T	A	-0.8626
89	A	A	0.0000
90	V	A	-0.4130
91	Y	A	0.0000
92	Y	A	-0.2501
93	C	A	0.0000
94	A	A	0.0000
95	A	A	0.0000
96	Y	A	-0.2262
97	A	A	-0.7556
98	H	A	-1.7315
99	K	A	-2.2654
100	L	A	-1.3555
101	P	A	-1.2896
102	S	A	-1.2843
103	R	A	-1.8644
104	I	A	-1.3652
105	S	A	-1.6639
106	F	A	-1.6937
107	D	A	-2.7870
108	K	A	-2.8728
109	F	A	0.0000
110	F	A	0.0000
111	E	A	-2.8841
112	A	A	-2.0558
113	A	A	0.0000
114	A	A	-2.0547
115	K	A	-2.7551
116	D	A	-2.2069
117	P	A	-1.2349
118	S	A	-0.4900
119	V	A	0.0613
120	F	A	0.0000
121	A	A	0.0887
122	F	A	0.0111
123	W	A	0.1123
124	G	A	-0.2909
125	Q	A	-0.9646
126	G	A	-0.5851
127	T	A	0.0000
128	Q	A	-0.9887
129	V	A	0.0000
130	T	A	-0.3798
131	V	A	0.0000
132	S	A	-0.8080
133	S	A	-0.5348