Project name: 6.P2G4.pdb

Chain sequence(s)	H: EVQLVESGGGLVQAGGSLKLSCAASGNSIRSLHMGWYRQAPGKQRELVAIITSTSNTNYADSVKGRFTVSRDNTKNTVYLQMNNLKPEDTAVYYCNARLANIYWGRGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:40)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:41)

• Minimal score value: -2.8023
• Maximal score value: 1.1675
• Average score: -0.8275
• Total score value: -94.3317

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.0809
2	V	H	0.0000
3	Q	H	-0.8935
4	L	H	0.0000
5	V	H	1.1256
6	E	H	0.0856
7	S	H	-0.3909
8	G	H	-1.1164
9	G	H	-0.6456
11	G	H	0.2268
12	L	H	1.1675
13	V	H	0.0500
14	Q	H	-1.3747
15	A	H	-1.6614
16	G	H	-1.8364
17	G	H	-1.2619
18	S	H	-1.4899
19	L	H	-0.8971
20	K	H	-1.6975
21	L	H	0.0000
22	S	H	-0.2810
23	C	H	0.0000
24	A	H	0.0245
25	A	H	0.0000
26	S	H	-0.9922
27	G	H	-1.4159
28	N	H	-1.5654
29	S	H	-1.6384
30	I	H	0.0000
35	R	H	-2.7109
36	S	H	-1.5598
37	L	H	0.0000
38	H	H	-1.3079
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	Y	H	0.3534
43	R	H	0.0000
44	Q	H	-1.2197
45	A	H	-1.2866
46	P	H	-0.9527
47	G	H	-1.3311
48	K	H	-1.9331
49	Q	H	-2.2135
50	R	H	-1.7244
51	E	H	-0.9097
52	L	H	0.2204
53	V	H	0.0000
54	A	H	0.0000
55	I	H	-0.1036
56	I	H	0.0000
57	T	H	-1.3712
58	S	H	-1.3293
59	T	H	-1.0052
63	S	H	-1.4107
64	N	H	-1.6511
65	T	H	-1.1811
66	N	H	-1.6951
67	Y	H	-1.2771
68	A	H	-1.3903
69	D	H	-2.6720
70	S	H	-1.8165
71	V	H	0.0000
72	K	H	-2.8023
74	G	H	-1.8988
75	R	H	-2.0470
76	F	H	0.0000
77	T	H	-0.9153
78	V	H	0.0000
79	S	H	-0.4368
80	R	H	-1.1135
81	D	H	-1.5820
82	N	H	-2.0805
83	T	H	-1.6646
84	K	H	-2.3790
85	N	H	-1.9978
86	T	H	-1.0037
87	V	H	0.0000
88	Y	H	-0.3660
89	L	H	0.0000
90	Q	H	-1.0768
91	M	H	0.0000
92	N	H	-1.9211
93	N	H	-2.3856
94	L	H	0.0000
95	K	H	-2.6955
96	P	H	-1.8703
97	E	H	-2.3302
98	D	H	0.0000
99	T	H	-0.8051
100	A	H	0.0000
101	V	H	-0.3156
102	Y	H	0.0000
103	Y	H	-0.0840
104	C	H	0.0000
105	N	H	0.0000
106	A	H	0.0000
107	R	H	-1.4420
108	L	H	-0.7742
114	A	H	-0.4008
115	N	H	-1.0857
116	I	H	0.0971
117	Y	H	-0.0252
118	W	H	0.3495
119	G	H	-0.2420
120	R	H	-1.4076
121	G	H	-0.7229
122	T	H	-0.6454
123	Q	H	-0.5630
124	V	H	0.0000
125	T	H	-0.1765
126	V	H	0.0000
127	S	H	-0.6560
128	S	H	-0.8276