Project name: 66af1c2e16f7092

Chain sequence(s)	A: SGLVPRGSHMSNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSVMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITVKQHTVTTTTKGENFTETDIKIMERVVEQMCITQYQRESQAYYQRGAS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:03:32)
[INFO]       Main:     Simulation completed successfully.                                          (00:03:34)

• Minimal score value: -4.1815
• Maximal score value: 2.5803
• Average score: -0.8056
• Total score value: -115.2039

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
92	S	A	0.0734
93	G	A	0.6132
94	L	A	1.8904
95	V	A	1.8567
96	P	A	0.1585
97	R	A	-1.5230
98	G	A	-1.5157
99	S	A	-1.5132
100	H	A	-1.7622
101	M	A	-0.7509
102	S	A	-1.5599
103	N	A	-2.3536
104	K	A	-2.8020
105	P	A	-1.9180
106	S	A	-2.0510
107	K	A	-2.6015
108	P	A	-2.3764
109	K	A	-2.6630
110	T	A	-1.8795
111	N	A	-1.6713
112	M	A	-0.3727
113	K	A	-1.8567
114	H	A	-1.0961
115	V	A	0.5643
116	A	A	0.1909
117	G	A	0.1022
118	A	A	0.0523
119	A	A	0.0386
120	A	A	0.0029
121	A	A	0.3537
122	G	A	0.6920
123	A	A	1.2744
124	V	A	2.5803
125	V	A	2.5166
126	G	A	1.0122
127	G	A	1.1018
128	L	A	1.9264
129	G	A	0.9253
130	G	A	0.1626
131	Y	A	0.7042
132	M	A	1.1715
133	L	A	0.9921
134	G	A	0.6744
135	S	A	0.9534
136	V	A	1.8043
137	M	A	1.4247
138	S	A	-0.1154
139	R	A	-1.4843
140	P	A	-0.6991
141	L	A	-0.0092
142	I	A	-1.0510
143	H	A	-1.5588
144	F	A	-1.7372
145	G	A	-1.8943
146	N	A	-2.9949
147	D	A	-3.2167
148	Y	A	-1.9305
149	E	A	-2.7475
150	D	A	-4.1815
151	R	A	-3.8546
152	Y	A	-1.8548
153	Y	A	0.0000
154	R	A	-3.3223
155	E	A	-2.8903
156	N	A	0.0000
157	M	A	-0.5341
158	Y	A	0.5298
159	R	A	-0.6429
160	Y	A	0.0000
161	P	A	0.2342
162	N	A	0.0000
163	Q	A	0.0325
164	V	A	0.0000
165	Y	A	0.4830
166	Y	A	0.3545
167	R	A	-0.5724
168	P	A	-0.4080
169	V	A	0.3703
170	D	A	-1.4277
171	Q	A	-1.1462
172	Y	A	-0.1133
173	S	A	-1.4439
174	N	A	-2.4706
175	Q	A	-2.7274
176	N	A	-2.9127
177	N	A	-3.0030
178	F	A	-1.6474
179	V	A	-1.1726
180	H	A	-2.2821
181	D	A	-1.7425
182	C	A	0.0000
183	V	A	-0.3089
184	N	A	-1.3667
185	I	A	0.0000
186	T	A	0.0000
187	V	A	0.9469
188	K	A	-0.3715
189	Q	A	0.1008
190	H	A	0.4030
191	T	A	0.3964
192	V	A	1.2147
193	T	A	-0.1851
194	T	A	-1.1052
195	T	A	-0.4393
196	T	A	-0.9829
197	K	A	-2.6146
198	G	A	-2.2836
199	E	A	-3.1965
200	N	A	-2.7897
201	F	A	-1.1461
202	T	A	-1.4662
203	E	A	-2.0309
204	T	A	-1.0989
205	D	A	0.0000
206	I	A	-1.3342
207	K	A	-2.6329
208	I	A	0.0000
209	M	A	-1.7605
210	E	A	-3.3484
211	R	A	-3.3031
212	V	A	0.0000
213	V	A	-1.6766
214	E	A	-2.4474
215	Q	A	-1.4137
216	M	A	0.0000
217	C	A	0.0000
218	I	A	0.2760
219	T	A	-0.5578
220	Q	A	-0.7388
221	Y	A	-0.8307
222	Q	A	-1.5624
223	R	A	-2.2127
224	E	A	-1.5834
225	S	A	0.0000
226	Q	A	-1.8131
227	A	A	-1.0690
228	Y	A	0.0708
229	Y	A	0.0629
230	Q	A	-1.4650
231	R	A	-1.8994
232	G	A	-0.8318
233	A	A	-0.3738
234	S	A	-0.1963