Project name: 68c30da5704a40d

Chain sequence(s)	A: MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKPEAAKPIENERMQRARFMRQSNFGTIGQTPETSLAQTESSKKGELFALRFLPILPKSLNAKTLDKVSNTKLTVSKVKGKFDAAGPGPGGDLPVTFWEGQGVGLGPGPGCGDLPVTFWEGQGVGAAYKVKVSVTTLGPGPGQSMPVHLRF
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:02)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:02)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:02)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:02)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:02)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:48)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:51)

• Minimal score value: -4.068
• Maximal score value: 5.6436
• Average score: -0.0342
• Total score value: -7.2465

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	1.3895
2	R	A	0.5319
3	V	A	2.7212
4	L	A	3.2328
5	Y	A	3.2278
6	L	A	3.5483
7	L	A	4.2112
8	F	A	4.5979
9	S	A	4.4402
10	F	A	5.3363
11	L	A	5.3095
12	F	A	5.6247
13	I	A	5.6436
14	F	A	5.3889
15	L	A	4.5989
16	M	A	3.3461
17	P	A	2.4042
18	L	A	2.5674
19	P	A	0.8571
20	G	A	0.9015
21	V	A	2.4466
22	F	A	2.4222
23	G	A	0.7196
24	G	A	0.2222
25	I	A	0.1308
26	G	A	-0.2990
27	D	A	-0.2269
28	P	A	0.6772
29	V	A	1.4863
30	T	A	0.3064
31	C	A	0.0000
32	L	A	1.2500
33	K	A	-0.5848
34	S	A	-0.2481
35	G	A	-0.7388
36	A	A	0.0000
37	I	A	0.4344
38	C	A	0.8711
39	H	A	0.3132
40	P	A	0.8783
41	V	A	1.9585
42	F	A	1.6246
43	C	A	-0.4709
44	P	A	-1.4821
45	R	A	-2.8536
46	R	A	-3.4059
47	Y	A	-2.8548
48	K	A	-3.0187
49	Q	A	-1.7503
50	I	A	-0.7996
51	G	A	-0.9175
52	T	A	-0.6690
53	C	A	0.0000
54	G	A	-0.1566
55	L	A	0.7617
56	P	A	0.2492
57	G	A	0.3056
58	T	A	0.3678
59	K	A	-0.3800
60	C	A	0.0000
61	C	A	0.0000
62	K	A	-2.2399
63	K	A	-3.4923
64	P	A	-2.7333
65	E	A	-2.6497
66	A	A	-1.6437
67	A	A	-0.9979
68	K	A	-1.8160
69	P	A	-0.7372
70	I	A	0.1643
71	E	A	-2.3621
72	N	A	-2.6867
73	E	A	-4.0680
74	R	A	-3.9700
75	M	A	-2.5338
76	Q	A	-3.6853
77	R	A	-3.4757
78	A	A	-2.3997
79	R	A	-2.8003
80	F	A	-0.8949
81	M	A	-0.9743
82	R	A	-2.5359
83	Q	A	-1.7892
84	S	A	-1.0017
85	N	A	-0.8889
86	F	A	0.6592
87	G	A	-0.0177
88	T	A	0.6319
89	I	A	1.5097
90	G	A	-0.0164
91	Q	A	-1.0659
92	T	A	-1.1427
93	P	A	-1.4886
94	E	A	-2.0418
95	T	A	-0.8423
96	S	A	0.1944
97	L	A	1.2069
98	A	A	-0.0004
99	Q	A	-1.3792
100	T	A	-1.7238
101	E	A	-2.5034
102	S	A	-2.0356
103	S	A	-2.0995
104	K	A	-3.3000
105	K	A	-3.1515
106	G	A	-2.0408
107	E	A	-1.4787
108	L	A	1.4718
109	F	A	2.3664
110	A	A	1.6801
111	L	A	2.1267
112	R	A	0.5164
113	F	A	2.3956
114	L	A	2.7680
115	P	A	2.1854
116	I	A	3.0098
117	L	A	2.0387
118	P	A	0.2766
119	K	A	-1.0784
120	S	A	-0.4504
121	L	A	0.2200
122	N	A	-1.0300
123	A	A	-0.9140
124	K	A	-1.7548
125	T	A	-0.9290
126	L	A	-0.0230
127	D	A	-1.7480
128	K	A	-1.5160
129	V	A	0.3001
130	S	A	-0.9485
131	N	A	-1.4223
132	T	A	-0.7827
133	K	A	-1.0350
134	L	A	1.3549
135	T	A	1.1845
136	V	A	1.7908
137	S	A	0.3655
138	K	A	-1.2195
139	V	A	-0.6497
140	K	A	-2.3650
141	G	A	-2.0093
142	K	A	-2.2670
143	F	A	-0.3588
144	D	A	-1.4061
145	A	A	-0.5441
146	A	A	-0.4604
147	G	A	-0.9288
148	P	A	-0.7958
149	G	A	-0.9950
150	P	A	-1.1076
151	G	A	-1.2440
152	G	A	-1.0736
153	D	A	-1.2899
154	L	A	0.7001
155	P	A	0.8916
156	V	A	2.1687
157	T	A	1.7982
158	F	A	2.3085
159	W	A	1.1125
160	E	A	-1.3622
161	G	A	-1.2935
162	Q	A	-1.5850
163	G	A	-0.3637
164	V	A	1.2917
165	G	A	0.6956
166	L	A	1.4018
167	G	A	0.0995
168	P	A	-0.4004
169	G	A	-0.7059
170	P	A	-0.7038
171	G	A	-0.7685
172	C	A	-0.1096
173	G	A	-0.7737
174	D	A	-0.9365
175	L	A	0.9712
176	P	A	1.0465
177	V	A	2.4715
178	T	A	1.9499
179	F	A	2.3923
180	W	A	1.1528
181	E	A	-1.3525
182	G	A	-1.2926
183	Q	A	-1.6280
184	G	A	-0.7154
185	V	A	0.9887
186	G	A	0.3288
187	A	A	0.3862
188	A	A	0.4385
189	Y	A	0.4247
190	K	A	-1.5048
191	V	A	-0.9263
192	K	A	-2.1289
193	V	A	-0.3509
194	S	A	0.4597
195	V	A	2.1364
196	T	A	1.2960
197	T	A	0.8648
198	L	A	1.0804
199	G	A	-0.3119
200	P	A	-0.4966
201	G	A	-0.9087
202	P	A	-0.9774
203	G	A	-1.0672
204	Q	A	-1.0578
205	S	A	-0.1056
206	M	A	0.8446
207	P	A	0.2119
208	V	A	0.2827
209	H	A	-1.0940
210	L	A	-0.4301
211	R	A	-1.0371
212	F	A	1.1320