Project name: 68d29d6e3ed9f43

Chain sequence(s)	L: KSVLELLDKVPYHD
Selected Chain(s)	L
Distance of aggregation	5 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with L chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:26)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:26)

• Minimal score value: -1.9682
• Maximal score value: 1.8044
• Average score: -0.3072
• Total score value: -4.3004

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
647	K	L	-1.6941
648	S	L	-0.1983
649	V	L	1.8044
650	L	L	0.1939
651	E	L	-1.4714
652	L	L	1.4537
653	L	L	1.2757
654	D	L	-1.8660
655	K	L	-1.9578
656	V	L	0.0274
657	P	L	0.0803
658	Y	L	1.0950
659	H	L	-1.0750
660	D	L	-1.9682