Project name: 68e403314bc41d

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGFSFSNYSMAWVRQAPGKGLEWVSVISSNGGNISYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARISALQVQLQSVTYLMDYWGQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:31)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:32)

• Minimal score value: -2.6544
• Maximal score value: 2.266
• Average score: -0.4354
• Total score value: -54.866

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.4745
2	V	H	-0.6012
3	Q	H	-0.8907
4	L	H	0.0000
5	V	H	1.1179
6	E	H	0.4739
7	S	H	-0.1388
8	G	H	-0.8047
9	G	H	0.0390
10	G	H	0.5564
11	L	H	1.3151
12	V	H	0.0000
13	Q	H	-1.3829
14	P	H	-1.6262
15	G	H	-1.4548
16	G	H	-1.0752
17	S	H	-1.2946
18	L	H	-0.9768
19	R	H	-2.0595
20	L	H	0.0000
21	S	H	-0.4189
22	C	H	0.0000
23	A	H	-0.0876
24	A	H	0.0000
25	S	H	-0.5675
26	G	H	-0.5813
27	F	H	0.6725
28	S	H	-0.0071
29	F	H	0.0000
30	S	H	-1.2475
31	N	H	-1.3715
32	Y	H	-0.5331
33	S	H	0.0000
34	M	H	0.0000
35	A	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6528
40	A	H	-1.0742
41	P	H	-0.8990
42	G	H	-1.4731
43	K	H	-2.2556
44	G	H	-1.2002
45	L	H	0.0444
46	E	H	-0.5620
47	W	H	0.0678
48	V	H	0.0000
49	S	H	0.0000
50	V	H	0.0000
51	I	H	0.0000
52	S	H	0.0000
52A	S	H	-1.4578
53	N	H	-1.9043
54	G	H	-1.1752
55	G	H	-1.0403
56	N	H	-0.5836
57	I	H	0.4578
58	S	H	-0.2242
59	Y	H	-0.7829
60	A	H	-1.5620
61	D	H	-2.5087
62	S	H	-1.7832
63	V	H	0.0000
64	K	H	-2.6544
65	G	H	-1.7712
66	R	H	-1.5360
67	F	H	0.0000
68	T	H	-0.7052
69	I	H	0.0000
70	S	H	-0.2160
71	R	H	-1.1277
72	D	H	-1.5796
73	N	H	-2.1635
74	S	H	-1.6775
75	K	H	-2.4142
76	N	H	-1.6664
77	T	H	-1.0212
78	L	H	0.0000
79	Y	H	-0.4731
80	L	H	0.0000
81	Q	H	-1.1277
82	M	H	0.0000
82A	N	H	-1.4143
82B	S	H	-1.2330
82C	L	H	0.0000
83	R	H	-2.2254
84	A	H	-1.6963
85	E	H	-2.1971
86	D	H	0.0000
87	T	H	-0.4005
88	A	H	0.0000
89	V	H	0.8348
90	Y	H	0.0000
91	Y	H	0.4322
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	I	H	0.0000
96	S	H	-0.3874
97	A	H	-0.0439
98	L	H	0.0442
99	Q	H	-0.7371
100	V	H	0.4804
100A	Q	H	0.0000
100B	L	H	0.7685
100C	Q	H	-0.2726
100D	S	H	0.0000
100E	V	H	1.6381
100F	T	H	1.2923
100G	Y	H	2.1687
100H	L	H	2.2660
100I	M	H	0.0000
101	D	H	-0.0145
102	Y	H	0.2895
103	W	H	0.2817
104	G	H	0.0127
105	Q	H	-0.7412
106	G	H	0.0708
107	T	H	0.5533
108	L	H	1.5269
109	V	H	0.0000
110	T	H	0.2798
111	V	H	0.0000
112	S	H	-0.7404
113	S	H	-0.5798