| Chain sequence(s) |
A: PTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPSPLYSVEFSEEPFGVIVHRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPIEPREPAIHSEGQNVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | VT890A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 1.19084 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:00)
[INFO] FoldX: Building mutant model (00:02:54)
[INFO] FoldX: Starting FoldX energy minimalization (00:03:02)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:05:54)
[INFO] Main: Simulation completed successfully. (00:06:02)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 79 | P | A | -0.9538 | |
| 80 | T | A | -1.1462 | |
| 81 | Q | A | -1.6464 | |
| 82 | C | A | 0.0000 | |
| 83 | D | A | -2.0958 | |
| 84 | V | A | -1.2089 | |
| 85 | P | A | -0.9361 | |
| 86 | P | A | -0.7343 | |
| 87 | N | A | -1.0798 | |
| 88 | S | A | -0.5930 | |
| 89 | R | A | -0.6456 | |
| 90 | F | A | 0.0000 | |
| 91 | D | A | -0.3499 | |
| 92 | C | A | 0.0000 | |
| 93 | A | A | -0.6193 | |
| 94 | P | A | -0.6409 | |
| 95 | D | A | -1.1588 | |
| 96 | K | A | -1.8036 | |
| 97 | A | A | -0.7941 | |
| 98 | I | A | -0.9831 | |
| 99 | T | A | -1.4750 | |
| 100 | Q | A | -2.2837 | |
| 101 | E | A | -3.2221 | |
| 102 | Q | A | -2.4902 | |
| 103 | C | A | 0.0000 | |
| 104 | E | A | -3.0721 | |
| 105 | A | A | -2.0119 | |
| 106 | R | A | -1.5699 | |
| 107 | G | A | -1.2775 | |
| 108 | C | A | 0.0000 | |
| 109 | C | A | 0.0000 | |
| 110 | Y | A | -0.2194 | |
| 111 | I | A | 0.5155 | |
| 112 | P | A | -0.1521 | |
| 113 | A | A | -0.9434 | |
| 114 | K | A | -2.1456 | |
| 115 | Q | A | -2.1050 | |
| 122 | M | A | 0.2832 | |
| 123 | G | A | -0.3411 | |
| 124 | Q | A | -0.5491 | |
| 125 | P | A | 0.0000 | |
| 126 | W | A | 0.6722 | |
| 127 | C | A | 0.0000 | |
| 128 | F | A | 0.0000 | |
| 129 | F | A | 0.0000 | |
| 130 | P | A | 0.0000 | |
| 131 | P | A | -0.6735 | |
| 132 | S | A | -0.8267 | |
| 133 | Y | A | 0.0000 | |
| 134 | P | A | -0.6728 | |
| 135 | S | A | -0.7449 | |
| 136 | Y | A | 0.0000 | |
| 137 | K | A | -2.3237 | |
| 138 | L | A | 0.0000 | |
| 139 | E | A | -2.0246 | |
| 140 | N | A | -1.3175 | |
| 141 | L | A | -0.2779 | |
| 142 | S | A | -0.2756 | |
| 143 | S | A | -0.5203 | |
| 144 | S | A | -0.7985 | |
| 145 | E | A | -1.5436 | |
| 146 | M | A | -0.2991 | |
| 147 | G | A | 0.0000 | |
| 148 | Y | A | 0.1705 | |
| 149 | T | A | -0.1583 | |
| 150 | A | A | 0.0000 | |
| 151 | T | A | -1.0187 | |
| 152 | L | A | 0.0000 | |
| 153 | T | A | -0.5662 | |
| 154 | R | A | 0.0000 | |
| 155 | T | A | -0.1703 | |
| 156 | T | A | -0.1280 | |
| 157 | P | A | -0.4391 | |
| 158 | T | A | -0.3113 | |
| 159 | F | A | -0.0718 | |
| 160 | F | A | 0.0000 | |
| 161 | P | A | -1.1783 | |
| 162 | K | A | -1.9438 | |
| 163 | D | A | -0.9690 | |
| 164 | I | A | -0.2924 | |
| 165 | L | A | 0.3503 | |
| 166 | T | A | -0.0969 | |
| 167 | L | A | 0.0000 | |
| 168 | R | A | -1.1688 | |
| 169 | L | A | 0.0000 | |
| 170 | D | A | 0.0000 | |
| 171 | V | A | 0.0000 | |
| 172 | M | A | 0.0059 | |
| 173 | M | A | -0.4322 | |
| 174 | E | A | -0.9247 | |
| 175 | T | A | -1.4023 | |
| 176 | E | A | -2.2402 | |
| 177 | N | A | -1.5488 | |
| 178 | R | A | -1.2141 | |
| 179 | L | A | 0.0000 | |
| 180 | H | A | -0.1843 | |
| 181 | F | A | 0.0000 | |
| 182 | T | A | 0.0000 | |
| 183 | I | A | 0.0000 | |
| 184 | K | A | -1.4203 | |
| 185 | D | A | 0.0000 | |
| 186 | P | A | -1.3567 | |
| 187 | A | A | -1.2406 | |
| 188 | N | A | -2.3562 | |
| 189 | R | A | -2.7651 | |
| 190 | R | A | -1.7424 | |
| 191 | Y | A | -0.7628 | |
| 192 | E | A | -0.9129 | |
| 193 | V | A | 0.0000 | |
| 194 | P | A | -0.4322 | |
| 195 | L | A | -0.6605 | |
| 196 | E | A | -1.7313 | |
| 197 | T | A | -1.1079 | |
| 198 | P | A | -0.9788 | |
| 206 | S | A | -0.8097 | |
| 207 | P | A | -1.1586 | |
| 208 | L | A | -0.6123 | |
| 209 | Y | A | 0.0000 | |
| 210 | S | A | -0.4434 | |
| 211 | V | A | -0.7422 | |
| 212 | E | A | -1.7993 | |
| 213 | F | A | -1.1312 | |
| 214 | S | A | -1.7869 | |
| 215 | E | A | -3.1590 | |
| 216 | E | A | -3.1785 | |
| 217 | P | A | -1.9402 | |
| 218 | F | A | 0.0000 | |
| 219 | G | A | 0.0000 | |
| 220 | V | A | 0.0000 | |
| 221 | I | A | -0.3118 | |
| 222 | V | A | 0.0000 | |
| 223 | H | A | -0.6893 | |
| 224 | R | A | 0.0000 | |
| 225 | Q | A | -0.6921 | |
| 226 | L | A | 0.1399 | |
| 227 | D | A | -1.5123 | |
| 228 | G | A | -1.1728 | |
| 229 | R | A | -0.9124 | |
| 230 | V | A | 0.0227 | |
| 231 | L | A | 0.0000 | |
| 232 | L | A | 0.0000 | |
| 233 | N | A | -0.0558 | |
| 234 | T | A | 0.0000 | |
| 235 | T | A | -0.2160 | |
| 236 | V | A | 0.5727 | |
| 237 | A | A | 0.0000 | |
| 238 | P | A | 0.0000 | |
| 239 | L | A | 0.0000 | |
| 240 | F | A | 0.0000 | |
| 241 | F | A | 0.0000 | |
| 242 | A | A | 0.0000 | |
| 243 | D | A | -1.1696 | |
| 244 | Q | A | -0.8563 | |
| 245 | F | A | 0.0000 | |
| 246 | L | A | 0.0000 | |
| 247 | Q | A | 0.0000 | |
| 248 | L | A | 0.0000 | |
| 249 | S | A | 0.0000 | |
| 250 | T | A | 0.0000 | |
| 251 | S | A | 0.1092 | |
| 252 | L | A | 0.0000 | |
| 253 | P | A | -0.3986 | |
| 254 | S | A | -0.6958 | |
| 255 | Q | A | -0.8154 | |
| 256 | Y | A | -0.1959 | |
| 257 | I | A | 0.0000 | |
| 258 | T | A | 0.0000 | |
| 259 | G | A | 0.0000 | |
| 260 | L | A | 0.0000 | |
| 261 | A | A | 0.0000 | |
| 262 | E | A | 0.0000 | |
| 263 | H | A | -0.2188 | |
| 264 | L | A | -0.1523 | |
| 265 | S | A | -0.2318 | |
| 266 | P | A | -0.3078 | |
| 267 | L | A | 0.0000 | |
| 268 | M | A | 0.0316 | |
| 269 | L | A | -0.0346 | |
| 270 | S | A | -0.4480 | |
| 271 | T | A | -0.4740 | |
| 272 | S | A | -0.5923 | |
| 273 | W | A | -0.4644 | |
| 274 | T | A | -0.7941 | |
| 275 | R | A | -1.6686 | |
| 276 | I | A | 0.0000 | |
| 277 | T | A | 0.0000 | |
| 278 | L | A | 0.0000 | |
| 279 | W | A | 0.0000 | |
| 280 | N | A | 0.0000 | |
| 281 | R | A | -0.2128 | |
| 282 | D | A | -0.1268 | |
| 283 | L | A | 0.1307 | |
| 284 | A | A | 0.0594 | |
| 285 | P | A | 0.0000 | |
| 286 | T | A | -0.1695 | |
| 287 | P | A | -0.4713 | |
| 288 | G | A | -0.8177 | |
| 289 | A | A | 0.0000 | |
| 290 | N | A | 0.0000 | |
| 291 | L | A | 0.0000 | |
| 292 | Y | A | 0.0000 | |
| 293 | G | A | 0.0000 | |
| 294 | S | A | 0.0000 | |
| 295 | H | A | 0.0000 | |
| 296 | P | A | 0.0000 | |
| 297 | F | A | 0.0000 | |
| 298 | Y | A | 0.0000 | |
| 299 | L | A | 0.0000 | |
| 300 | A | A | 0.0000 | |
| 301 | L | A | 0.0000 | |
| 302 | E | A | 0.0000 | |
| 303 | D | A | -2.3633 | |
| 304 | G | A | -1.8914 | |
| 305 | G | A | 0.0000 | |
| 306 | S | A | -1.3780 | |
| 307 | A | A | 0.0000 | |
| 308 | H | A | 0.0000 | |
| 309 | G | A | 0.0000 | |
| 310 | V | A | 0.0000 | |
| 311 | F | A | 0.0000 | |
| 312 | L | A | 0.0000 | |
| 313 | L | A | 0.0000 | |
| 314 | N | A | 0.0000 | |
| 315 | S | A | 0.0000 | |
| 316 | N | A | 0.0000 | |
| 317 | A | A | 0.0000 | |
| 318 | M | A | 0.0000 | |
| 319 | D | A | 0.0000 | |
| 320 | V | A | 0.0000 | |
| 321 | V | A | 0.0000 | |
| 322 | L | A | 0.0000 | |
| 323 | Q | A | 0.0000 | |
| 324 | P | A | -0.6423 | |
| 325 | S | A | -0.6773 | |
| 326 | P | A | -0.4694 | |
| 327 | A | A | 0.0000 | |
| 328 | L | A | 0.0000 | |
| 329 | S | A | 0.0000 | |
| 330 | W | A | 0.0000 | |
| 331 | R | A | 0.0000 | |
| 332 | S | A | 0.0000 | |
| 333 | T | A | 0.0000 | |
| 334 | G | A | 0.0000 | |
| 335 | G | A | 0.0000 | |
| 336 | I | A | -0.4739 | |
| 337 | L | A | 0.0000 | |
| 338 | D | A | 0.0000 | |
| 339 | V | A | 0.0000 | |
| 340 | Y | A | 0.0000 | |
| 341 | I | A | 0.0000 | |
| 342 | F | A | 0.0000 | |
| 343 | L | A | 0.0000 | |
| 344 | G | A | 0.0000 | |
| 345 | P | A | -0.7365 | |
| 346 | E | A | -1.8829 | |
| 347 | P | A | 0.0000 | |
| 348 | K | A | -1.1875 | |
| 349 | S | A | -1.0438 | |
| 350 | V | A | 0.0000 | |
| 351 | V | A | 0.0000 | |
| 352 | Q | A | -1.0491 | |
| 353 | Q | A | 0.0000 | |
| 354 | Y | A | 0.0000 | |
| 355 | L | A | 0.0000 | |
| 356 | D | A | -1.2730 | |
| 357 | V | A | 0.0000 | |
| 358 | V | A | 0.0000 | |
| 359 | G | A | -0.7533 | |
| 360 | Y | A | -0.2187 | |
| 361 | P | A | 0.0000 | |
| 362 | F | A | 0.0000 | |
| 363 | M | A | -0.0108 | |
| 364 | P | A | 0.0000 | |
| 365 | P | A | 0.0000 | |
| 366 | Y | A | 0.0000 | |
| 367 | W | A | 0.0000 | |
| 368 | G | A | 0.0000 | |
| 369 | L | A | 0.0000 | |
| 370 | G | A | 0.0000 | |
| 371 | F | A | 0.0000 | |
| 372 | H | A | 0.0000 | |
| 373 | L | A | 0.0000 | |
| 374 | C | A | 0.0000 | |
| 375 | R | A | -0.0799 | |
| 376 | W | A | 0.4362 | |
| 377 | G | A | 0.3540 | |
| 378 | Y | A | 0.0000 | |
| 379 | S | A | -0.3196 | |
| 380 | S | A | -0.9453 | |
| 381 | T | A | 0.0000 | |
| 382 | A | A | -0.0581 | |
| 383 | I | A | 0.2439 | |
| 384 | T | A | 0.0000 | |
| 385 | R | A | -1.2967 | |
| 386 | Q | A | -1.7168 | |
| 387 | V | A | 0.0000 | |
| 388 | V | A | -1.4410 | |
| 389 | E | A | -2.8929 | |
| 390 | N | A | -2.1516 | |
| 391 | M | A | 0.0000 | |
| 392 | T | A | -1.9787 | |
| 393 | R | A | -2.6670 | |
| 394 | A | A | -1.8160 | |
| 395 | H | A | -1.9069 | |
| 396 | F | A | 0.0000 | |
| 397 | P | A | 0.0000 | |
| 398 | L | A | 0.0000 | |
| 399 | D | A | 0.0000 | |
| 400 | V | A | 0.0000 | |
| 401 | Q | A | 0.0000 | |
| 402 | W | A | 0.0000 | |
| 403 | N | A | 0.0000 | |
| 404 | D | A | 0.0000 | |
| 405 | L | A | 0.0000 | |
| 406 | D | A | -0.6426 | |
| 407 | Y | A | 0.0000 | |
| 408 | M | A | 0.0000 | |
| 409 | D | A | -1.7771 | |
| 410 | S | A | -1.1577 | |
| 411 | R | A | -1.5258 | |
| 412 | R | A | -1.0629 | |
| 413 | D | A | 0.0000 | |
| 414 | F | A | 0.0000 | |
| 415 | T | A | -0.9334 | |
| 416 | F | A | 0.0000 | |
| 417 | N | A | -2.7004 | |
| 418 | K | A | -3.7977 | |
| 419 | D | A | -3.5619 | |
| 420 | G | A | -2.0769 | |
| 421 | F | A | 0.0000 | |
| 422 | R | A | -3.7033 | |
| 423 | D | A | -2.2800 | |
| 424 | F | A | 0.0000 | |
| 425 | P | A | -1.5558 | |
| 426 | A | A | -1.4383 | |
| 427 | M | A | 0.0000 | |
| 428 | V | A | 0.0000 | |
| 429 | Q | A | -2.4016 | |
| 430 | E | A | -2.7354 | |
| 431 | L | A | 0.0000 | |
| 432 | H | A | -1.9465 | |
| 433 | Q | A | -2.4070 | |
| 434 | G | A | -1.8215 | |
| 435 | G | A | -1.1818 | |
| 436 | R | A | 0.0000 | |
| 437 | R | A | -0.8309 | |
| 438 | Y | A | 0.0000 | |
| 439 | M | A | 0.0000 | |
| 440 | M | A | 0.0000 | |
| 441 | I | A | 0.0000 | |
| 442 | V | A | 0.0000 | |
| 443 | D | A | 0.0000 | |
| 444 | P | A | 0.0000 | |
| 445 | A | A | 0.0000 | |
| 446 | I | A | 0.0000 | |
| 447 | S | A | 0.0000 | |
| 448 | S | A | -0.1906 | |
| 449 | S | A | -0.3863 | |
| 450 | G | A | -0.7222 | |
| 451 | P | A | -0.6261 | |
| 452 | A | A | -0.6862 | |
| 453 | G | A | -1.0127 | |
| 454 | S | A | -0.9306 | |
| 455 | Y | A | 0.0000 | |
| 456 | R | A | -1.3983 | |
| 457 | P | A | 0.0000 | |
| 458 | Y | A | -0.6940 | |
| 459 | D | A | -1.2954 | |
| 460 | E | A | 0.0000 | |
| 461 | G | A | 0.0000 | |
| 462 | L | A | -0.8071 | |
| 463 | R | A | -1.9654 | |
| 464 | R | A | -1.5146 | |
| 465 | G | A | -1.2038 | |
| 466 | V | A | 0.0000 | |
| 467 | F | A | 0.0000 | |
| 468 | I | A | 0.0000 | |
| 469 | T | A | -1.3706 | |
| 470 | N | A | -2.2541 | |
| 471 | E | A | -2.5898 | |
| 472 | T | A | -1.6723 | |
| 473 | G | A | -1.9490 | |
| 474 | Q | A | -1.9636 | |
| 475 | P | A | -1.0440 | |
| 476 | L | A | 0.0000 | |
| 477 | I | A | -0.7920 | |
| 478 | G | A | 0.0000 | |
| 479 | K | A | -0.3509 | |
| 480 | V | A | 0.0000 | |
| 481 | W | A | 0.0417 | |
| 482 | P | A | -0.6714 | |
| 483 | G | A | -0.3045 | |
| 484 | S | A | -0.5035 | |
| 485 | T | A | 0.0000 | |
| 486 | A | A | 0.0000 | |
| 487 | F | A | 0.0000 | |
| 488 | P | A | 0.0000 | |
| 489 | D | A | 0.0000 | |
| 490 | F | A | 0.0000 | |
| 491 | T | A | 0.6924 | |
| 492 | N | A | 0.5584 | |
| 493 | P | A | 0.0175 | |
| 494 | T | A | -0.1471 | |
| 495 | A | A | 0.0000 | |
| 496 | L | A | -0.1923 | |
| 497 | A | A | -0.4876 | |
| 498 | W | A | 0.0000 | |
| 499 | W | A | 0.0000 | |
| 500 | E | A | 0.0000 | |
| 501 | D | A | -1.5207 | |
| 502 | M | A | 0.0000 | |
| 503 | V | A | 0.0000 | |
| 504 | A | A | -1.6600 | |
| 505 | E | A | -1.8026 | |
| 506 | F | A | 0.0000 | |
| 507 | H | A | -1.6973 | |
| 508 | D | A | -2.5364 | |
| 509 | Q | A | -1.9179 | |
| 510 | V | A | 0.0000 | |
| 511 | P | A | -1.2009 | |
| 512 | F | A | 0.0000 | |
| 513 | D | A | 0.0000 | |
| 514 | G | A | 0.0000 | |
| 515 | M | A | 0.0000 | |
| 516 | W | A | 0.0000 | |
| 517 | I | A | 0.0000 | |
| 518 | D | A | 0.0000 | |
| 519 | M | A | 0.0000 | |
| 520 | N | A | 0.0000 | |
| 521 | E | A | 0.0000 | |
| 522 | P | A | 0.0000 | |
| 523 | S | A | 0.0000 | |
| 524 | N | A | 0.0000 | |
| 525 | F | A | 1.1117 | |
| 526 | I | A | -0.1327 | |
| 527 | R | A | -1.7250 | |
| 528 | G | A | 0.0000 | |
| 529 | S | A | 0.0000 | |
| 530 | E | A | -2.3311 | |
| 531 | D | A | -2.6714 | |
| 532 | G | A | -1.8822 | |
| 533 | C | A | -1.4884 | |
| 534 | P | A | -1.6665 | |
| 535 | N | A | -2.1014 | |
| 536 | N | A | -2.1729 | |
| 537 | E | A | -2.6619 | |
| 538 | L | A | -1.3821 | |
| 539 | E | A | 0.0000 | |
| 540 | N | A | -2.1677 | |
| 541 | P | A | 0.0000 | |
| 542 | P | A | -0.9163 | |
| 543 | Y | A | 0.0000 | |
| 544 | V | A | 0.2755 | |
| 545 | P | A | 0.0000 | |
| 546 | G | A | -0.4461 | |
| 547 | V | A | 0.0000 | |
| 548 | V | A | 0.0605 | |
| 549 | G | A | -0.4453 | |
| 550 | G | A | -0.4127 | |
| 551 | T | A | -0.5522 | |
| 552 | L | A | 0.0000 | |
| 553 | Q | A | 0.0000 | |
| 554 | A | A | -0.4822 | |
| 555 | A | A | -0.0306 | |
| 556 | T | A | 0.0000 | |
| 557 | I | A | 0.0000 | |
| 558 | C | A | 0.0000 | |
| 559 | A | A | 0.0000 | |
| 560 | S | A | -1.1856 | |
| 561 | S | A | 0.0000 | |
| 562 | H | A | -1.0868 | |
| 563 | Q | A | 0.5627 | |
| 564 | F | A | 2.0749 | |
| 565 | L | A | 1.6835 | |
| 566 | S | A | 0.6716 | |
| 567 | T | A | 0.0695 | |
| 568 | H | A | 0.0000 | |
| 569 | Y | A | 0.0000 | |
| 570 | N | A | -0.0786 | |
| 571 | L | A | 0.0000 | |
| 572 | H | A | 0.0000 | |
| 573 | N | A | 0.0000 | |
| 574 | L | A | 0.0000 | |
| 575 | Y | A | 0.0000 | |
| 576 | G | A | 0.0000 | |
| 577 | L | A | 0.2626 | |
| 578 | T | A | 0.2849 | |
| 579 | E | A | 0.0000 | |
| 580 | A | A | 0.0000 | |
| 581 | I | A | 0.2464 | |
| 582 | A | A | 0.0000 | |
| 583 | S | A | 0.0000 | |
| 584 | H | A | -0.6882 | |
| 585 | R | A | -1.3826 | |
| 586 | A | A | 0.0000 | |
| 587 | L | A | 0.0000 | |
| 588 | V | A | -1.1107 | |
| 589 | K | A | -2.2174 | |
| 590 | A | A | -1.7130 | |
| 591 | R | A | -1.1748 | |
| 592 | G | A | -1.0485 | |
| 593 | T | A | -0.8591 | |
| 594 | R | A | 0.0000 | |
| 595 | P | A | 0.0000 | |
| 596 | F | A | 0.0000 | |
| 597 | V | A | 0.0000 | |
| 598 | I | A | 0.0000 | |
| 599 | S | A | 0.0000 | |
| 600 | R | A | 0.0000 | |
| 601 | S | A | 0.0000 | |
| 602 | T | A | 0.0000 | |
| 603 | F | A | 0.0000 | |
| 604 | A | A | 0.0000 | |
| 605 | G | A | 0.0000 | |
| 606 | H | A | 0.0000 | |
| 607 | G | A | 0.0000 | |
| 608 | R | A | -0.4809 | |
| 609 | Y | A | -0.1243 | |
| 610 | A | A | 0.0000 | |
| 611 | G | A | 0.0000 | |
| 612 | H | A | 0.0000 | |
| 613 | W | A | 0.0000 | |
| 614 | T | A | 0.0000 | |
| 615 | G | A | 0.0000 | |
| 616 | D | A | -0.0503 | |
| 617 | V | A | 0.0000 | |
| 618 | W | A | 0.0222 | |
| 619 | S | A | -0.4483 | |
| 620 | S | A | -0.7600 | |
| 621 | W | A | -1.0750 | |
| 622 | E | A | -1.9039 | |
| 623 | Q | A | -0.8172 | |
| 624 | L | A | 0.0000 | |
| 625 | A | A | 0.0000 | |
| 626 | S | A | -0.6866 | |
| 627 | S | A | 0.0000 | |
| 628 | V | A | 0.0000 | |
| 629 | P | A | 0.0000 | |
| 630 | E | A | 0.0000 | |
| 631 | I | A | 0.0000 | |
| 632 | L | A | 0.0000 | |
| 633 | Q | A | 0.0000 | |
| 634 | F | A | 0.0000 | |
| 635 | N | A | 0.0000 | |
| 636 | L | A | 0.0000 | |
| 637 | L | A | 0.0000 | |
| 638 | G | A | 0.0000 | |
| 639 | V | A | 0.0000 | |
| 640 | P | A | 0.0000 | |
| 641 | L | A | 0.0000 | |
| 642 | V | A | 0.0000 | |
| 643 | G | A | 0.0000 | |
| 644 | A | A | 0.0000 | |
| 645 | D | A | 0.0000 | |
| 646 | V | A | 0.0000 | |
| 647 | C | A | 0.0000 | |
| 648 | G | A | 0.0000 | |
| 649 | F | A | 0.0000 | |
| 650 | L | A | 0.2718 | |
| 651 | G | A | -0.3090 | |
| 652 | N | A | -1.0632 | |
| 653 | T | A | 0.0000 | |
| 654 | S | A | -1.0493 | |
| 655 | E | A | -1.3921 | |
| 656 | E | A | -1.3145 | |
| 657 | L | A | 0.0000 | |
| 658 | C | A | 0.0000 | |
| 659 | V | A | 0.0000 | |
| 660 | R | A | 0.0000 | |
| 661 | W | A | 0.0000 | |
| 662 | T | A | 0.0000 | |
| 663 | Q | A | 0.0000 | |
| 664 | L | A | 0.0000 | |
| 665 | G | A | 0.0000 | |
| 666 | A | A | 0.0000 | |
| 667 | F | A | 0.0000 | |
| 668 | Y | A | 0.0000 | |
| 669 | P | A | 0.0000 | |
| 670 | F | A | 0.0000 | |
| 671 | M | A | 0.0000 | |
| 672 | R | A | 0.0000 | |
| 673 | N | A | 0.0000 | |
| 674 | H | A | 0.0000 | |
| 675 | N | A | 0.0000 | |
| 676 | S | A | 0.6793 | |
| 677 | L | A | 1.4451 | |
| 678 | L | A | 1.7874 | |
| 679 | S | A | 0.6949 | |
| 680 | L | A | 0.5189 | |
| 681 | P | A | 0.1545 | |
| 682 | Q | A | 0.0000 | |
| 683 | E | A | 0.0000 | |
| 684 | P | A | 0.0000 | |
| 685 | Y | A | -0.7305 | |
| 686 | S | A | -0.2690 | |
| 687 | F | A | -0.7760 | |
| 688 | S | A | -1.2540 | |
| 689 | E | A | -2.2773 | |
| 690 | P | A | -1.8171 | |
| 691 | A | A | 0.0000 | |
| 692 | Q | A | -2.0002 | |
| 693 | Q | A | -2.5603 | |
| 694 | A | A | 0.0000 | |
| 695 | M | A | 0.0000 | |
| 696 | R | A | -1.4180 | |
| 697 | K | A | -1.9264 | |
| 698 | A | A | 0.0000 | |
| 699 | L | A | 0.0000 | |
| 700 | T | A | -0.6955 | |
| 701 | L | A | -0.2525 | |
| 702 | R | A | 0.0000 | |
| 703 | Y | A | 0.0000 | |
| 704 | A | A | 0.0000 | |
| 705 | L | A | 0.0000 | |
| 706 | L | A | 0.0000 | |
| 707 | P | A | 0.0000 | |
| 708 | H | A | 0.0000 | |
| 709 | L | A | 0.0000 | |
| 710 | Y | A | 0.0000 | |
| 711 | T | A | 0.0000 | |
| 712 | L | A | -0.2367 | |
| 713 | F | A | 0.0000 | |
| 714 | H | A | 0.0000 | |
| 715 | Q | A | -0.1243 | |
| 716 | A | A | 0.0000 | |
| 717 | H | A | -0.0005 | |
| 718 | V | A | 0.6485 | |
| 719 | A | A | -0.0577 | |
| 720 | G | A | 0.0000 | |
| 721 | E | A | -0.4741 | |
| 722 | T | A | 0.0000 | |
| 723 | V | A | 0.0000 | |
| 724 | A | A | 0.0000 | |
| 725 | R | A | 0.0000 | |
| 726 | P | A | 0.0000 | |
| 727 | L | A | 0.0000 | |
| 728 | F | A | 0.0000 | |
| 729 | L | A | 0.0000 | |
| 730 | E | A | -0.8410 | |
| 731 | F | A | -0.6295 | |
| 732 | P | A | -1.5944 | |
| 733 | K | A | -2.4972 | |
| 734 | D | A | -1.2102 | |
| 735 | S | A | -1.2814 | |
| 736 | S | A | -0.8410 | |
| 737 | T | A | 0.0000 | |
| 738 | W | A | 0.0000 | |
| 739 | T | A | -0.0882 | |
| 740 | V | A | -0.1197 | |
| 741 | D | A | -0.4338 | |
| 742 | H | A | -0.6753 | |
| 743 | Q | A | 0.0000 | |
| 744 | L | A | 0.0000 | |
| 745 | L | A | 0.0000 | |
| 746 | W | A | 0.0000 | |
| 747 | G | A | 0.0000 | |
| 748 | E | A | -0.8234 | |
| 749 | A | A | 0.0000 | |
| 750 | L | A | 0.0000 | |
| 751 | L | A | 0.0000 | |
| 752 | I | A | 0.0000 | |
| 753 | T | A | 0.0000 | |
| 754 | P | A | 0.0000 | |
| 755 | V | A | 0.0000 | |
| 756 | L | A | 0.0000 | |
| 757 | Q | A | -1.8866 | |
| 758 | A | A | -1.0529 | |
| 759 | G | A | -1.3538 | |
| 760 | K | A | -1.6922 | |
| 761 | A | A | -1.3602 | |
| 762 | E | A | -1.6993 | |
| 763 | V | A | -0.8236 | |
| 764 | T | A | -0.6167 | |
| 765 | G | A | 0.0000 | |
| 766 | Y | A | 0.0000 | |
| 767 | F | A | 0.0000 | |
| 768 | P | A | 0.0000 | |
| 769 | L | A | 0.3180 | |
| 770 | G | A | -0.3934 | |
| 771 | T | A | 0.0000 | |
| 772 | W | A | 0.0000 | |
| 773 | Y | A | 0.0000 | |
| 774 | D | A | 0.0000 | |
| 775 | L | A | 0.0000 | |
| 776 | Q | A | -1.0298 | |
| 777 | T | A | -0.7818 | |
| 778 | V | A | 0.0000 | |
| 779 | P | A | -0.4584 | |
| 780 | I | A | -0.3216 | |
| 781 | E | A | -1.5869 | |
| 793 | P | A | -0.8331 | |
| 794 | R | A | -1.3881 | |
| 795 | E | A | -1.9226 | |
| 796 | P | A | -1.5670 | |
| 797 | A | A | -0.9483 | |
| 798 | I | A | 0.0000 | |
| 799 | H | A | -1.3821 | |
| 800 | S | A | 0.0000 | |
| 801 | E | A | -1.8193 | |
| 802 | G | A | -1.1276 | |
| 803 | Q | A | -1.5980 | |
| 804 | N | A | -1.7503 | |
| 805 | V | A | -0.6003 | |
| 806 | T | A | -0.5451 | |
| 807 | L | A | 0.0000 | |
| 808 | P | A | -0.9353 | |
| 809 | A | A | 0.0000 | |
| 810 | P | A | -0.8518 | |
| 811 | L | A | -0.7167 | |
| 812 | D | A | -1.8249 | |
| 813 | T | A | 0.0000 | |
| 814 | I | A | -0.3038 | |
| 815 | N | A | 0.0000 | |
| 816 | V | A | 0.0000 | |
| 817 | H | A | 0.0000 | |
| 818 | L | A | 0.0000 | |
| 819 | R | A | -0.2956 | |
| 820 | A | A | -0.9424 | |
| 821 | G | A | -1.1407 | |
| 822 | Y | A | -0.9233 | |
| 823 | I | A | 0.0000 | |
| 824 | I | A | 0.0000 | |
| 825 | P | A | 0.0000 | |
| 826 | L | A | 0.0000 | |
| 827 | Q | A | 0.0000 | |
| 828 | G | A | -0.9863 | |
| 829 | P | A | -0.9164 | |
| 830 | G | A | -0.8361 | |
| 831 | L | A | -0.3372 | |
| 832 | T | A | 0.0000 | |
| 833 | T | A | 0.0000 | |
| 834 | T | A | -1.0736 | |
| 835 | E | A | -1.8206 | |
| 836 | S | A | 0.0000 | |
| 837 | R | A | -1.5245 | |
| 838 | Q | A | -2.0455 | |
| 839 | Q | A | -1.5022 | |
| 840 | P | A | -1.0881 | |
| 841 | M | A | 0.0000 | |
| 842 | A | A | -0.3481 | |
| 843 | L | A | 0.0000 | |
| 844 | A | A | 0.0000 | |
| 845 | V | A | 0.0000 | |
| 846 | A | A | 0.0000 | |
| 847 | L | A | 0.0000 | |
| 848 | T | A | -1.6881 | |
| 849 | K | A | -2.2015 | |
| 850 | G | A | -2.2181 | |
| 851 | G | A | -2.4520 | |
| 852 | E | A | -2.8623 | |
| 853 | A | A | 0.0000 | |
| 854 | R | A | -2.1465 | |
| 855 | G | A | 0.0000 | |
| 856 | E | A | -1.2101 | |
| 857 | L | A | 0.0000 | |
| 858 | F | A | 0.0000 | |
| 859 | W | A | 0.0000 | |
| 860 | D | A | 0.0000 | |
| 861 | D | A | -1.4916 | |
| 862 | G | A | 0.0000 | |
| 863 | E | A | -1.3203 | |
| 864 | S | A | -1.0062 | |
| 865 | L | A | -1.2805 | |
| 866 | E | A | -2.7143 | |
| 867 | V | A | 0.0000 | |
| 868 | L | A | -1.3736 | |
| 869 | E | A | -3.0089 | |
| 870 | R | A | -2.9456 | |
| 871 | G | A | -1.5491 | |
| 872 | A | A | -1.2487 | |
| 873 | Y | A | -0.6452 | |
| 874 | T | A | 0.0000 | |
| 875 | Q | A | -0.6260 | |
| 876 | V | A | 0.0000 | |
| 877 | I | A | -0.7211 | |
| 878 | F | A | 0.0000 | |
| 879 | L | A | -1.0650 | |
| 880 | A | A | 0.0000 | |
| 881 | R | A | -3.2529 | |
| 882 | N | A | -2.7066 | |
| 883 | N | A | -1.8781 | |
| 884 | T | A | -0.9759 | |
| 885 | I | A | 0.0000 | |
| 886 | V | A | -0.2687 | |
| 887 | N | A | 0.0000 | |
| 888 | E | A | -1.6508 | |
| 889 | L | A | -0.9016 | |
| 890 | T | A | -0.6272 | mutated: VT890A |
| 891 | R | A | -0.7674 | |
| 892 | V | A | -0.0196 | |
| 893 | T | A | -0.1334 | |
| 894 | S | A | -0.4215 | |
| 895 | E | A | -0.7355 | |
| 896 | G | A | 0.0000 | |
| 897 | A | A | -0.5076 | |
| 898 | G | A | -1.0187 | |
| 899 | L | A | 0.0000 | |
| 900 | Q | A | -1.2473 | |
| 901 | L | A | 0.0000 | |
| 902 | Q | A | -0.9813 | |
| 903 | K | A | -0.6176 | |
| 904 | V | A | 0.0000 | |
| 905 | T | A | 0.0000 | |
| 906 | V | A | 0.0000 | |
| 907 | L | A | 0.0000 | |
| 908 | G | A | -0.8459 | |
| 909 | V | A | 0.0000 | |
| 910 | A | A | -0.7146 | |
| 911 | T | A | -0.2753 | |
| 912 | A | A | -0.3782 | |
| 913 | P | A | -0.4640 | |
| 914 | Q | A | -1.2302 | |
| 915 | Q | A | -0.5068 | |
| 916 | V | A | 0.0000 | |
| 917 | L | A | 0.7119 | |
| 918 | S | A | 0.2689 | |
| 919 | N | A | -0.6780 | |
| 920 | G | A | 0.0390 | |
| 921 | V | A | 1.1765 | |
| 922 | P | A | 0.3360 | |
| 923 | V | A | 0.1148 | |
| 924 | S | A | -0.2924 | |
| 925 | N | A | -0.9580 | |
| 926 | F | A | -0.0664 | |
| 927 | T | A | -0.0429 | |
| 928 | Y | A | -0.3132 | |
| 929 | S | A | -0.9910 | |
| 930 | P | A | -1.4005 | |
| 931 | D | A | -2.3152 | |
| 932 | T | A | -1.6132 | |
| 933 | K | A | -1.5595 | |
| 934 | V | A | 0.0000 | |
| 935 | L | A | 0.0000 | |
| 936 | D | A | -0.3772 | |
| 937 | I | A | 0.0000 | |
| 938 | C | A | -0.2250 | |
| 939 | V | A | 0.0000 | |
| 940 | S | A | -0.4260 | |
| 941 | L | A | -0.7164 | |
| 942 | L | A | -0.9111 | |
| 943 | M | A | 0.0000 | |
| 944 | G | A | 0.0000 | |
| 945 | E | A | -2.3724 | |
| 946 | Q | A | -2.1472 | |
| 947 | F | A | 0.0000 | |
| 948 | L | A | 0.3139 | |
| 949 | V | A | 0.0000 | |
| 950 | S | A | -0.2268 | |
| 951 | W | A | 0.0000 | |
| 952 | C | A | 0.0110 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine