Project name: 6a59e72a3fa442a

Chain sequence(s)	A: LIVTQTMMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLLRVYVEEELKPTPEGDLEILLQKWENGECAQKKIIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMMENSAEPEQSLACQCLVRTPEVDDEALEKFDKKALKALPMHIRLSSFNPTQLEEQCHI
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:24)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:25)

• Minimal score value: -3.9094
• Maximal score value: 1.2592
• Average score: -1.0486
• Total score value: -169.879

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	L	A	1.2592
2	I	A	0.6534
3	V	A	0.0000
4	T	A	0.3364
5	Q	A	-0.3561
6	T	A	-0.6077
7	M	A	-1.1539
8	K	A	-1.9420
9	G	A	-1.3744
10	L	A	0.0000
11	D	A	-1.4517
12	I	A	-1.3696
13	Q	A	-2.1787
14	K	A	-2.4800
15	V	A	0.0000
16	A	A	-1.2291
17	G	A	-0.9998
18	T	A	-0.7220
19	W	A	0.0000
20	Y	A	-0.8011
21	S	A	0.0000
22	L	A	0.0000
23	A	A	0.0000
24	M	A	0.0000
25	A	A	0.0000
26	A	A	0.0000
27	S	A	-0.9141
28	D	A	-1.0630
29	I	A	0.4258
30	S	A	-0.3203
31	L	A	-0.2798
32	L	A	0.0000
33	D	A	-1.7608
34	A	A	-1.3096
35	Q	A	-1.7979
36	S	A	-1.7793
37	A	A	-0.9470
38	P	A	-0.6882
39	L	A	-0.2457
40	R	A	-0.6547
41	V	A	-0.2214
42	Y	A	0.0000
43	V	A	0.0000
44	E	A	-1.5926
45	E	A	-1.4526
46	L	A	0.0000
47	K	A	-1.3573
48	P	A	-1.7068
49	T	A	-1.4566
50	P	A	-1.5224
51	E	A	-2.3162
52	G	A	0.0000
53	D	A	-1.9693
54	L	A	0.0000
55	E	A	-0.8699
56	I	A	0.0000
57	L	A	-1.3582
58	L	A	0.0000
59	Q	A	0.0000
60	K	A	0.0000
61	W	A	-2.0051
62	E	A	-2.7626
63	N	A	-2.6552
64	G	A	-2.3924
65	E	A	-3.0875
66	C	A	-1.8287
67	A	A	-1.8852
68	Q	A	-2.4021
69	K	A	-2.0511
70	K	A	-1.9387
71	I	A	-0.5234
72	I	A	-0.2757
73	A	A	0.0000
74	E	A	-2.1081
75	K	A	-1.9363
76	T	A	-1.4027
77	K	A	-1.3779
78	I	A	-0.1392
79	P	A	-0.6213
80	A	A	0.0000
81	V	A	-0.4437
82	F	A	0.0000
83	K	A	-1.9432
84	I	A	-1.6684
85	D	A	-2.1845
86	A	A	-0.8499
87	L	A	0.4926
88	N	A	-0.9902
89	E	A	-2.1999
90	N	A	-1.7718
91	K	A	-1.4502
92	V	A	0.0000
93	L	A	0.0000
94	V	A	0.0000
95	L	A	0.0000
96	D	A	-0.8879
97	T	A	0.0000
98	D	A	-1.5308
99	Y	A	-1.9189
100	K	A	-2.7834
101	K	A	-2.8535
102	Y	A	0.0000
103	L	A	0.0000
104	L	A	0.0000
105	F	A	0.0000
106	C	A	0.0000
107	M	A	-0.1722
108	E	A	0.0000
109	N	A	-1.5638
110	S	A	-1.4893
111	A	A	-2.2752
112	E	A	-2.9538
113	P	A	-2.8032
114	E	A	-3.4633
115	Q	A	-2.6475
116	S	A	-1.7480
117	L	A	0.0000
118	A	A	0.0000
119	C	A	0.0000
120	Q	A	0.0000
121	C	A	0.0000
122	L	A	0.0000
123	V	A	0.0000
124	R	A	-1.6644
125	T	A	-1.2838
126	P	A	-1.4217
127	E	A	-1.9021
128	V	A	-0.5394
129	D	A	-2.0440
130	D	A	-3.1097
131	E	A	-3.4431
132	A	A	0.0000
133	L	A	-2.3996
134	E	A	-3.9094
135	K	A	-3.0213
136	F	A	0.0000
137	D	A	-3.1870
138	K	A	-3.3625
139	A	A	-2.1243
140	L	A	0.0000
141	K	A	-2.4712
142	A	A	-1.2157
143	L	A	0.0000
144	P	A	-0.8141
145	M	A	-0.7249
146	H	A	-0.8371
147	I	A	-0.4839
148	R	A	-1.0583
149	L	A	-0.4691
150	S	A	-0.3446
151	F	A	0.0000
152	N	A	-1.5675
153	P	A	-1.6559
154	T	A	-1.4417
155	Q	A	-1.3730
156	L	A	0.0000
157	E	A	-2.9707
158	E	A	-2.4159
159	Q	A	-2.2172
160	C	A	0.0000
161	H	A	0.0000
162	I	A	0.6623