| Chain sequence(s) |
A: MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ
B: MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ input PDB |
| Selected Chain(s) | A,B |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | HR257B,HR257A |
| Energy difference between WT (input) and mutated protein (by FoldX) | -1.74916 kcal/mol |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with all chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:02)
[INFO] FoldX: Building mutant model (00:12:52)
[INFO] FoldX: Starting FoldX energy minimalization (00:14:08)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:19:50)
[INFO] Main: Simulation completed successfully. (00:19:59)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | 0.5729 | |
| 2 | P | A | -0.6843 | |
| 3 | N | A | -1.7946 | |
| 4 | S | A | -1.7082 | |
| 5 | E | A | -2.4634 | |
| 6 | P | A | -1.5048 | |
| 7 | A | A | -0.9512 | |
| 8 | S | A | -0.8660 | |
| 9 | L | A | -0.2957 | |
| 10 | L | A | -0.6487 | |
| 11 | E | A | -1.8531 | |
| 12 | L | A | -0.9949 | |
| 13 | F | A | 0.0000 | |
| 14 | N | A | -1.6678 | |
| 15 | S | A | -1.2457 | |
| 16 | I | A | 0.0000 | |
| 17 | A | A | -1.1821 | |
| 18 | T | A | -1.0180 | |
| 19 | Q | A | 0.0000 | |
| 20 | G | A | -0.8565 | |
| 21 | E | A | -2.3501 | |
| 22 | L | A | -0.8916 | |
| 23 | V | A | 0.0000 | |
| 24 | R | A | -2.8311 | |
| 25 | S | A | -1.9466 | |
| 26 | L | A | -2.2427 | |
| 27 | K | A | -3.0772 | |
| 28 | A | A | -1.6205 | |
| 29 | G | A | -1.6451 | |
| 30 | N | A | -1.9780 | |
| 31 | A | A | -2.0936 | |
| 32 | S | A | -2.8087 | |
| 33 | K | A | -3.9176 | |
| 34 | D | A | -3.9940 | |
| 35 | E | A | -3.8290 | |
| 36 | I | A | -3.2782 | |
| 37 | D | A | -3.4785 | |
| 38 | S | A | -2.3008 | |
| 39 | A | A | 0.0000 | |
| 40 | V | A | -0.6253 | |
| 41 | K | A | -1.1194 | |
| 42 | M | A | 0.6350 | |
| 43 | L | A | 0.7187 | |
| 44 | V | A | 1.6204 | |
| 45 | S | A | 0.7695 | |
| 46 | L | A | 0.5250 | |
| 47 | K | A | -0.5772 | |
| 48 | M | A | 0.3860 | |
| 49 | S | A | 0.0517 | |
| 50 | Y | A | 0.0000 | |
| 51 | K | A | -2.0167 | |
| 52 | A | A | -0.9068 | |
| 53 | A | A | -0.6713 | |
| 54 | A | A | -1.0886 | |
| 55 | G | A | -1.8331 | |
| 56 | E | A | -3.3485 | |
| 57 | D | A | -3.3814 | |
| 58 | Y | A | -2.3567 | |
| 59 | K | A | -2.7547 | |
| 60 | A | A | -1.7575 | |
| 61 | D | A | -1.9787 | |
| 62 | C | A | -0.9187 | |
| 63 | P | A | -0.9710 | |
| 64 | P | A | -0.6974 | |
| 65 | G | A | -0.9841 | |
| 66 | N | A | -1.6352 | |
| 67 | P | A | -1.0670 | |
| 68 | A | A | -0.6637 | |
| 69 | P | A | -0.7448 | |
| 70 | T | A | -0.8331 | |
| 71 | S | A | -1.2889 | |
| 72 | N | A | -2.0293 | |
| 73 | H | A | -2.3072 | |
| 74 | G | A | -1.9551 | |
| 75 | P | A | -1.7159 | |
| 76 | D | A | -2.5267 | |
| 77 | A | A | -2.0204 | |
| 78 | T | A | -1.9733 | |
| 79 | E | A | -2.9129 | |
| 80 | A | A | -2.4635 | |
| 81 | E | A | -3.0376 | |
| 82 | E | A | -2.9692 | |
| 83 | D | A | 0.0000 | |
| 84 | F | A | 1.1261 | |
| 85 | V | A | 0.7019 | |
| 86 | D | A | 0.2259 | |
| 87 | P | A | -0.0638 | |
| 88 | W | A | 0.1762 | |
| 89 | T | A | 0.1875 | |
| 90 | V | A | 0.2582 | |
| 91 | Q | A | -0.6292 | |
| 92 | T | A | -1.5321 | |
| 93 | S | A | -1.4857 | |
| 94 | S | A | -1.8668 | |
| 95 | A | A | -1.3790 | |
| 96 | K | A | -2.5868 | |
| 97 | G | A | -1.7391 | |
| 98 | I | A | -1.5955 | |
| 99 | D | A | -3.0112 | |
| 100 | Y | A | -1.7479 | |
| 101 | D | A | -2.6852 | |
| 102 | K | A | -2.3758 | |
| 103 | L | A | 0.0000 | |
| 104 | I | A | -0.8596 | |
| 105 | V | A | 0.3580 | |
| 106 | R | A | -0.4059 | |
| 107 | F | A | 0.0000 | |
| 108 | G | A | -0.4327 | |
| 109 | S | A | -0.5514 | |
| 110 | S | A | -1.2781 | |
| 111 | K | A | -2.4683 | |
| 112 | I | A | 0.0000 | |
| 113 | D | A | -3.4576 | |
| 114 | K | A | -3.6229 | |
| 115 | E | A | -3.3542 | |
| 116 | L | A | 0.0000 | |
| 117 | I | A | -2.4273 | |
| 118 | N | A | -2.8190 | |
| 119 | R | A | -2.3126 | |
| 120 | I | A | 0.0000 | |
| 121 | E | A | -3.1423 | |
| 122 | R | A | -3.1251 | |
| 123 | A | A | -1.7769 | |
| 124 | T | A | -2.0057 | |
| 125 | G | A | -2.1825 | |
| 126 | Q | A | -2.5838 | |
| 127 | R | A | -2.9705 | |
| 128 | P | A | 0.0000 | |
| 129 | H | A | -1.1320 | |
| 130 | H | A | -1.4595 | |
| 131 | F | A | 0.0000 | |
| 132 | L | A | 0.0000 | |
| 133 | R | A | -1.5409 | |
| 134 | R | A | -0.8524 | |
| 135 | G | A | -0.9988 | |
| 136 | I | A | 0.0000 | |
| 137 | F | A | 0.0000 | |
| 138 | F | A | 0.0000 | |
| 139 | S | A | 0.0000 | |
| 140 | H | A | 0.0000 | |
| 141 | R | A | -1.3126 | |
| 142 | D | A | -1.6380 | |
| 143 | M | A | 0.0000 | |
| 144 | N | A | -1.7900 | |
| 145 | Q | A | -2.1143 | |
| 146 | V | A | 0.0000 | |
| 147 | L | A | 0.0000 | |
| 148 | D | A | -2.3828 | |
| 149 | A | A | -2.4169 | |
| 150 | Y | A | -2.1226 | |
| 151 | E | A | -2.6950 | |
| 152 | N | A | -3.1011 | |
| 153 | K | A | -3.3849 | |
| 154 | K | A | -3.3119 | |
| 155 | P | A | -1.8017 | |
| 156 | F | A | 0.0000 | |
| 157 | Y | A | 0.0000 | |
| 158 | L | A | 0.0000 | |
| 159 | Y | A | 0.0000 | |
| 160 | T | A | 0.0000 | |
| 161 | G | A | -0.2490 | |
| 162 | R | A | -0.3514 | |
| 163 | G | A | -0.2675 | |
| 164 | P | A | 0.0000 | |
| 165 | S | A | -0.6139 | |
| 166 | S | A | -1.1705 | |
| 167 | E | A | -2.1292 | |
| 168 | A | A | -1.0996 | |
| 169 | M | A | 0.0000 | |
| 170 | H | A | 0.0000 | |
| 171 | V | A | 0.0000 | |
| 172 | G | A | 0.0254 | |
| 173 | H | A | -0.1114 | |
| 174 | L | A | 0.0000 | |
| 175 | I | A | 0.0000 | |
| 176 | P | A | -0.0330 | |
| 177 | F | A | 0.0000 | |
| 178 | I | A | 0.3178 | |
| 179 | F | A | 0.0000 | |
| 180 | T | A | 0.0000 | |
| 181 | K | A | -0.6289 | |
| 182 | W | A | -0.6151 | |
| 183 | L | A | 0.0000 | |
| 184 | Q | A | 0.0000 | |
| 185 | D | A | -2.2249 | |
| 186 | V | A | -1.5404 | |
| 187 | F | A | 0.0000 | |
| 188 | N | A | -1.8098 | |
| 189 | V | A | 0.0000 | |
| 190 | P | A | 0.0000 | |
| 191 | L | A | 0.0000 | |
| 192 | V | A | 0.0000 | |
| 193 | I | A | 0.0000 | |
| 194 | Q | A | 0.0000 | |
| 195 | M | A | 0.0000 | |
| 196 | T | A | 0.0000 | |
| 197 | D | A | 0.0000 | |
| 198 | D | A | 0.0000 | |
| 199 | E | A | 0.0000 | |
| 200 | K | A | -0.6329 | |
| 201 | Y | A | 0.0000 | |
| 202 | L | A | 0.0000 | |
| 203 | W | A | -0.5718 | |
| 204 | K | A | -1.4978 | |
| 205 | D | A | -2.1021 | |
| 206 | L | A | -1.3365 | |
| 207 | T | A | -1.2277 | |
| 208 | L | A | 0.0000 | |
| 209 | D | A | -1.9389 | |
| 210 | Q | A | -1.7242 | |
| 211 | A | A | 0.0000 | |
| 212 | Y | A | -0.5484 | |
| 213 | S | A | -1.0476 | |
| 214 | Y | A | -1.1774 | |
| 215 | A | A | 0.0000 | |
| 216 | V | A | -0.9423 | |
| 217 | E | A | -1.6619 | |
| 218 | N | A | 0.0000 | |
| 219 | A | A | 0.0000 | |
| 220 | K | A | -1.4468 | |
| 221 | D | A | 0.0000 | |
| 222 | I | A | 0.0000 | |
| 223 | I | A | 0.0000 | |
| 224 | A | A | 0.0000 | |
| 225 | C | A | -0.4903 | |
| 226 | G | A | -0.4129 | |
| 227 | F | A | 0.0000 | |
| 228 | D | A | -1.1045 | |
| 229 | I | A | -0.6588 | |
| 230 | N | A | -1.8140 | |
| 231 | K | A | -1.5431 | |
| 232 | T | A | 0.0000 | |
| 233 | F | A | 0.0000 | |
| 234 | I | A | 0.0000 | |
| 235 | F | A | 0.0000 | |
| 236 | S | A | 0.0000 | |
| 237 | D | A | 0.0000 | |
| 238 | L | A | 0.0000 | |
| 239 | D | A | -0.1558 | |
| 240 | Y | A | 0.0000 | |
| 241 | M | A | 0.0000 | |
| 242 | G | A | 0.0000 | |
| 243 | M | A | 0.7247 | |
| 244 | S | A | 0.0000 | |
| 245 | S | A | -0.0312 | |
| 246 | G | A | -0.7039 | |
| 247 | F | A | 0.0000 | |
| 248 | Y | A | 0.0000 | |
| 249 | K | A | -0.5816 | |
| 250 | N | A | 0.0000 | |
| 251 | V | A | 0.0000 | |
| 252 | V | A | 0.0000 | |
| 253 | K | A | -0.8179 | |
| 254 | I | A | 0.0000 | |
| 255 | Q | A | 0.0000 | |
| 256 | K | A | -0.6237 | |
| 257 | R | A | -1.3127 | mutated: HR257A |
| 258 | V | A | 0.0000 | |
| 259 | T | A | -1.2575 | |
| 260 | F | A | 0.0000 | |
| 261 | N | A | -2.3510 | |
| 262 | Q | A | -1.6221 | |
| 263 | V | A | 0.0000 | |
| 264 | K | A | -2.0129 | |
| 265 | G | A | -1.1853 | |
| 266 | I | A | -0.2906 | |
| 267 | F | A | 0.0000 | |
| 268 | G | A | -1.0212 | |
| 269 | F | A | 0.0000 | |
| 270 | T | A | -1.4416 | |
| 271 | D | A | -2.1780 | |
| 272 | S | A | -1.2151 | |
| 273 | D | A | -1.0578 | |
| 274 | C | A | -0.7289 | |
| 275 | I | A | 0.0000 | |
| 276 | G | A | 0.0000 | |
| 277 | K | A | -0.2563 | |
| 278 | I | A | 0.0000 | |
| 279 | S | A | 0.0000 | |
| 280 | F | A | 0.0000 | |
| 281 | P | A | 0.0000 | |
| 282 | A | A | 0.0000 | |
| 283 | I | A | 0.0000 | |
| 284 | Q | A | 0.0000 | |
| 285 | A | A | 0.0000 | |
| 286 | A | A | 0.0000 | |
| 287 | P | A | 0.0000 | |
| 288 | S | A | 0.0000 | |
| 289 | F | A | 0.0000 | |
| 290 | S | A | 0.0000 | |
| 291 | N | A | -1.6563 | |
| 292 | S | A | 0.0000 | |
| 293 | F | A | 0.0000 | |
| 294 | P | A | -1.7967 | |
| 295 | Q | A | -1.5482 | |
| 296 | I | A | 0.0000 | |
| 297 | F | A | 0.0000 | |
| 298 | R | A | -3.1635 | |
| 299 | D | A | -3.1618 | |
| 300 | R | A | -2.5118 | |
| 301 | T | A | -1.8953 | |
| 302 | D | A | -2.5299 | |
| 303 | I | A | 0.0000 | |
| 304 | Q | A | -1.1635 | |
| 305 | C | A | 0.0000 | |
| 306 | L | A | 0.0000 | |
| 307 | I | A | 0.0000 | |
| 308 | P | A | 0.0000 | |
| 309 | C | A | 0.0000 | |
| 310 | A | A | -0.0838 | |
| 311 | I | A | 0.0000 | |
| 312 | D | A | -0.0436 | |
| 313 | Q | A | -0.4879 | |
| 314 | D | A | 0.0000 | |
| 315 | P | A | 0.0000 | |
| 316 | Y | A | 0.0000 | |
| 317 | F | A | 0.0000 | |
| 318 | R | A | -1.3016 | |
| 319 | M | A | 0.0000 | |
| 320 | T | A | 0.0000 | |
| 321 | R | A | -1.9117 | |
| 322 | D | A | -2.6416 | |
| 323 | V | A | 0.0000 | |
| 324 | A | A | 0.0000 | |
| 325 | P | A | -1.8305 | |
| 326 | R | A | -2.4611 | |
| 327 | I | A | -1.3135 | |
| 328 | G | A | -1.3072 | |
| 329 | Y | A | -1.1944 | |
| 330 | P | A | -1.1103 | |
| 331 | K | A | -1.8095 | |
| 332 | P | A | 0.0000 | |
| 333 | A | A | 0.0000 | |
| 334 | L | A | 0.0000 | |
| 335 | L | A | 0.0000 | |
| 336 | H | A | 0.0000 | |
| 337 | S | A | 0.0000 | |
| 338 | T | A | 0.0149 | |
| 339 | F | A | 0.4410 | |
| 340 | F | A | 0.3446 | |
| 341 | P | A | 0.0000 | |
| 342 | A | A | 0.0000 | |
| 343 | L | A | 0.0000 | |
| 344 | Q | A | -0.7568 | |
| 345 | G | A | 0.0000 | |
| 346 | A | A | -1.1148 | |
| 347 | Q | A | -1.9804 | |
| 348 | T | A | -1.4052 | |
| 349 | K | A | -1.7705 | |
| 350 | M | A | -0.9299 | |
| 351 | S | A | -0.8103 | |
| 352 | A | A | -0.7948 | |
| 353 | S | A | -0.7698 | |
| 354 | D | A | -1.3995 | |
| 355 | P | A | -0.9506 | |
| 356 | N | A | -1.3644 | |
| 357 | S | A | 0.0000 | |
| 358 | S | A | 0.0000 | |
| 359 | I | A | 0.0000 | |
| 360 | F | A | -0.0689 | |
| 361 | L | A | 0.0000 | |
| 362 | T | A | -0.3379 | |
| 363 | D | A | 0.0000 | |
| 364 | T | A | -1.1048 | |
| 365 | A | A | -1.6772 | |
| 366 | K | A | -2.5467 | |
| 367 | Q | A | -2.1469 | |
| 368 | I | A | 0.0000 | |
| 369 | K | A | -3.1307 | |
| 370 | T | A | -2.2190 | |
| 371 | K | A | 0.0000 | |
| 372 | V | A | 0.0000 | |
| 373 | N | A | -2.2533 | |
| 374 | K | A | -2.3429 | |
| 375 | H | A | -1.2271 | |
| 376 | A | A | 0.0000 | |
| 377 | F | A | 0.5424 | |
| 378 | S | A | -0.4223 | |
| 379 | G | A | 0.0000 | |
| 380 | G | A | -0.9672 | |
| 381 | R | A | -2.4227 | |
| 382 | D | A | -2.4735 | |
| 383 | T | A | -1.4650 | |
| 384 | I | A | -0.2148 | |
| 385 | E | A | -2.0792 | |
| 386 | E | A | -1.9601 | |
| 387 | H | A | 0.0000 | |
| 388 | R | A | -1.6995 | |
| 389 | Q | A | -1.4477 | |
| 390 | F | A | 0.1818 | |
| 391 | G | A | 0.0000 | |
| 392 | G | A | 0.0000 | |
| 393 | N | A | -1.5739 | |
| 394 | C | A | -1.7213 | |
| 395 | D | A | -2.3847 | |
| 396 | V | A | -1.1689 | |
| 397 | D | A | 0.0000 | |
| 398 | V | A | 0.0000 | |
| 399 | S | A | 0.0000 | |
| 400 | F | A | 0.0000 | |
| 401 | M | A | -0.0839 | |
| 402 | Y | A | 0.0000 | |
| 403 | L | A | 0.0000 | |
| 404 | T | A | -0.7174 | |
| 405 | F | A | 0.0000 | |
| 406 | F | A | 0.0000 | |
| 407 | L | A | 0.0000 | |
| 408 | E | A | -2.9391 | |
| 409 | D | A | -3.3395 | |
| 410 | D | A | -3.2630 | |
| 411 | D | A | -3.8132 | |
| 412 | K | A | -3.7112 | |
| 413 | L | A | 0.0000 | |
| 414 | E | A | -3.2550 | |
| 415 | Q | A | -3.3295 | |
| 416 | I | A | 0.0000 | |
| 417 | R | A | -2.7328 | |
| 418 | K | A | -2.7881 | |
| 419 | D | A | -1.8408 | |
| 420 | Y | A | 0.0000 | |
| 421 | T | A | -1.1824 | |
| 422 | S | A | -0.9395 | |
| 423 | G | A | 0.0000 | |
| 424 | A | A | -0.6282 | |
| 425 | M | A | -0.8281 | |
| 426 | L | A | -0.3770 | |
| 427 | T | A | -0.6229 | |
| 428 | G | A | -1.2124 | |
| 429 | E | A | -1.6604 | |
| 430 | L | A | 0.0000 | |
| 431 | K | A | 0.0000 | |
| 432 | K | A | -2.8307 | |
| 433 | A | A | -1.6637 | |
| 434 | L | A | 0.0000 | |
| 435 | I | A | 0.0000 | |
| 436 | E | A | -2.3806 | |
| 437 | V | A | -1.1207 | |
| 438 | L | A | 0.0000 | |
| 439 | Q | A | -1.4840 | |
| 440 | P | A | -1.0362 | |
| 441 | L | A | -0.6419 | |
| 442 | I | A | 0.0000 | |
| 443 | A | A | -1.0764 | |
| 444 | E | A | -2.0414 | |
| 445 | H | A | 0.0000 | |
| 446 | Q | A | -1.7578 | |
| 447 | A | A | -2.0321 | |
| 448 | R | A | -2.5231 | |
| 449 | R | A | -2.5682 | |
| 450 | K | A | -3.0288 | |
| 451 | E | A | -3.1314 | |
| 452 | V | A | 0.0000 | |
| 453 | T | A | -2.6340 | |
| 454 | D | A | -3.4794 | |
| 455 | E | A | -3.3711 | |
| 456 | I | A | -2.0742 | |
| 457 | V | A | 0.0000 | |
| 458 | K | A | -3.2930 | |
| 459 | E | A | -2.8979 | |
| 460 | F | A | 0.0000 | |
| 461 | M | A | -1.1210 | |
| 462 | T | A | -1.1592 | |
| 463 | P | A | -0.8777 | |
| 464 | R | A | -1.5754 | |
| 465 | K | A | -2.5605 | |
| 466 | L | A | 0.0000 | |
| 467 | S | A | -1.3545 | |
| 468 | F | A | -1.4930 | |
| 469 | D | A | -2.3769 | |
| 470 | F | A | -1.7770 | |
| 471 | Q | A | -2.0958 | |
| 1 | M | B | 0.5715 | |
| 2 | P | B | -0.6903 | |
| 3 | N | B | -1.7943 | |
| 4 | S | B | -1.7104 | |
| 5 | E | B | -2.4647 | |
| 6 | P | B | -1.5080 | |
| 7 | A | B | -0.9128 | |
| 8 | S | B | -0.7836 | |
| 9 | L | B | -0.1559 | |
| 10 | L | B | -0.3807 | |
| 11 | E | B | -1.7755 | |
| 12 | L | B | -0.8959 | |
| 13 | F | B | 0.0000 | |
| 14 | N | B | -1.6399 | |
| 15 | S | B | -1.2013 | |
| 16 | I | B | 0.0000 | |
| 17 | A | B | -1.1664 | |
| 18 | T | B | -1.0021 | |
| 19 | Q | B | 0.0000 | |
| 20 | G | B | -0.9726 | |
| 21 | E | B | -2.3428 | |
| 22 | L | B | -0.8866 | |
| 23 | V | B | 0.0000 | |
| 24 | R | B | -2.8285 | |
| 25 | S | B | -1.9350 | |
| 26 | L | B | -2.1691 | |
| 27 | K | B | -3.0857 | |
| 28 | A | B | -1.6105 | |
| 29 | G | B | -1.6493 | |
| 30 | N | B | -1.9595 | |
| 31 | A | B | -2.1387 | |
| 32 | S | B | -2.7441 | |
| 33 | K | B | -3.7354 | |
| 34 | D | B | -3.7687 | |
| 35 | E | B | -3.7294 | |
| 36 | I | B | -2.9567 | |
| 37 | D | B | -2.6971 | |
| 38 | S | B | -2.0488 | |
| 39 | A | B | 0.0000 | |
| 40 | V | B | -0.5759 | |
| 41 | K | B | -1.1740 | |
| 42 | M | B | 0.4338 | |
| 43 | L | B | 0.4275 | |
| 44 | V | B | 0.8368 | |
| 45 | S | B | 0.3148 | |
| 46 | L | B | 0.2486 | |
| 47 | K | B | -0.8142 | |
| 48 | M | B | -0.1522 | |
| 49 | S | B | -0.1898 | |
| 50 | Y | B | 0.0000 | |
| 51 | K | B | -2.0871 | |
| 52 | A | B | -0.9902 | |
| 53 | A | B | -0.7059 | |
| 54 | A | B | -1.1055 | |
| 55 | G | B | -1.8719 | |
| 56 | E | B | -3.3586 | |
| 57 | D | B | -3.3852 | |
| 58 | Y | B | -2.3304 | |
| 59 | K | B | -2.7329 | |
| 60 | A | B | -1.7716 | |
| 61 | D | B | -2.0142 | |
| 62 | C | B | -0.9948 | |
| 63 | P | B | -1.1152 | |
| 64 | P | B | -0.8031 | |
| 65 | G | B | -0.9025 | |
| 66 | N | B | -1.6357 | |
| 67 | P | B | -1.0623 | |
| 68 | A | B | -0.6689 | |
| 69 | P | B | -0.7569 | |
| 70 | T | B | -0.8554 | |
| 71 | S | B | -1.3153 | |
| 72 | N | B | -2.0500 | |
| 73 | H | B | -2.3153 | |
| 74 | G | B | -1.9879 | |
| 75 | P | B | -1.7279 | |
| 76 | D | B | -2.5243 | |
| 77 | A | B | -2.0137 | |
| 78 | T | B | -1.9582 | |
| 79 | E | B | -2.9062 | |
| 80 | A | B | -2.2707 | |
| 81 | E | B | -3.0217 | |
| 82 | E | B | -2.9946 | |
| 83 | D | B | 0.0000 | |
| 84 | F | B | 1.0940 | |
| 85 | V | B | 0.6811 | |
| 86 | D | B | 0.2001 | |
| 87 | P | B | -0.1250 | |
| 88 | W | B | 0.1842 | |
| 89 | T | B | 0.1764 | |
| 90 | V | B | 0.2093 | |
| 91 | Q | B | -0.6940 | |
| 92 | T | B | -1.5867 | |
| 93 | S | B | -1.4848 | |
| 94 | S | B | -1.8943 | |
| 95 | A | B | -1.4136 | |
| 96 | K | B | -2.6447 | |
| 97 | G | B | -1.8606 | |
| 98 | I | B | 0.0000 | |
| 99 | D | B | -3.1445 | |
| 100 | Y | B | -1.8447 | |
| 101 | D | B | -2.7629 | |
| 102 | K | B | -2.5004 | |
| 103 | L | B | 0.0000 | |
| 104 | I | B | 0.0000 | |
| 105 | V | B | 0.2833 | |
| 106 | R | B | -0.5093 | |
| 107 | F | B | -0.1399 | |
| 108 | G | B | -0.3862 | |
| 109 | S | B | -0.4964 | |
| 110 | S | B | -1.1452 | |
| 111 | K | B | -2.1907 | |
| 112 | I | B | 0.0000 | |
| 113 | D | B | -3.2739 | |
| 114 | K | B | -3.5582 | |
| 115 | E | B | -3.3350 | |
| 116 | L | B | 0.0000 | |
| 117 | I | B | -2.4392 | |
| 118 | N | B | -2.8470 | |
| 119 | R | B | -2.3295 | |
| 120 | I | B | 0.0000 | |
| 121 | E | B | -3.1648 | |
| 122 | R | B | -3.1474 | |
| 123 | A | B | -1.7948 | |
| 124 | T | B | 0.0000 | |
| 125 | G | B | -2.1743 | |
| 126 | Q | B | -2.5608 | |
| 127 | R | B | -2.9728 | |
| 128 | P | B | 0.0000 | |
| 129 | H | B | -1.1416 | |
| 130 | H | B | -1.4674 | |
| 131 | F | B | 0.0000 | |
| 132 | L | B | 0.0000 | |
| 133 | R | B | -1.5624 | |
| 134 | R | B | -0.8632 | |
| 135 | G | B | -0.9515 | |
| 136 | I | B | 0.0000 | |
| 137 | F | B | 0.0000 | |
| 138 | F | B | 0.0000 | |
| 139 | S | B | 0.0000 | |
| 140 | H | B | 0.0000 | |
| 141 | R | B | -1.2508 | |
| 142 | D | B | -1.6113 | |
| 143 | M | B | 0.0000 | |
| 144 | N | B | -1.7579 | |
| 145 | Q | B | -2.1142 | |
| 146 | V | B | 0.0000 | |
| 147 | L | B | 0.0000 | |
| 148 | D | B | -2.4363 | |
| 149 | A | B | -2.4788 | |
| 150 | Y | B | -2.2386 | |
| 151 | E | B | -2.8376 | |
| 152 | N | B | -3.1768 | |
| 153 | K | B | -3.4411 | |
| 154 | K | B | -3.3543 | |
| 155 | P | B | -1.9134 | |
| 156 | F | B | 0.0000 | |
| 157 | Y | B | 0.0000 | |
| 158 | L | B | 0.0000 | |
| 159 | Y | B | 0.0000 | |
| 160 | T | B | 0.0000 | |
| 161 | G | B | -0.2706 | |
| 162 | R | B | -0.3440 | |
| 163 | G | B | -0.2354 | |
| 164 | P | B | 0.0000 | |
| 165 | S | B | -0.6267 | |
| 166 | S | B | -1.1011 | |
| 167 | E | B | -1.9838 | |
| 168 | A | B | -0.9490 | |
| 169 | M | B | 0.0000 | |
| 170 | H | B | 0.0000 | |
| 171 | V | B | 0.0000 | |
| 172 | G | B | -0.0430 | |
| 173 | H | B | -0.1314 | |
| 174 | L | B | 0.0000 | |
| 175 | I | B | 0.0000 | |
| 176 | P | B | -0.0187 | |
| 177 | F | B | 0.0000 | |
| 178 | I | B | 0.3625 | |
| 179 | F | B | 0.0000 | |
| 180 | T | B | 0.0000 | |
| 181 | K | B | -0.5555 | |
| 182 | W | B | -0.5677 | |
| 183 | L | B | 0.0000 | |
| 184 | Q | B | 0.0000 | |
| 185 | D | B | -2.2033 | |
| 186 | V | B | -1.5297 | |
| 187 | F | B | 0.0000 | |
| 188 | N | B | -1.8088 | |
| 189 | V | B | 0.0000 | |
| 190 | P | B | 0.0000 | |
| 191 | L | B | 0.0000 | |
| 192 | V | B | 0.0000 | |
| 193 | I | B | 0.0000 | |
| 194 | Q | B | 0.0000 | |
| 195 | M | B | 0.0000 | |
| 196 | T | B | 0.0000 | |
| 197 | D | B | 0.0000 | |
| 198 | D | B | 0.0000 | |
| 199 | E | B | 0.0000 | |
| 200 | K | B | -0.6856 | |
| 201 | Y | B | 0.0000 | |
| 202 | L | B | 0.0000 | |
| 203 | W | B | -0.6399 | |
| 204 | K | B | -1.6318 | |
| 205 | D | B | -2.1675 | |
| 206 | L | B | -1.3757 | |
| 207 | T | B | -1.2728 | |
| 208 | L | B | 0.0000 | |
| 209 | D | B | -1.9528 | |
| 210 | Q | B | -1.7690 | |
| 211 | A | B | 0.0000 | |
| 212 | Y | B | -0.4654 | |
| 213 | S | B | -0.9332 | |
| 214 | Y | B | -0.9733 | |
| 215 | A | B | 0.0000 | |
| 216 | V | B | -0.6589 | |
| 217 | E | B | -1.0772 | |
| 218 | N | B | 0.0000 | |
| 219 | A | B | 0.0000 | |
| 220 | K | B | -0.9721 | |
| 221 | D | B | 0.0000 | |
| 222 | I | B | 0.0000 | |
| 223 | I | B | 0.0000 | |
| 224 | A | B | 0.0000 | |
| 225 | C | B | -0.4592 | |
| 226 | G | B | -0.4394 | |
| 227 | F | B | 0.0000 | |
| 228 | D | B | -1.0258 | |
| 229 | I | B | -0.4859 | |
| 230 | N | B | -1.7001 | |
| 231 | K | B | -1.4779 | |
| 232 | T | B | 0.0000 | |
| 233 | F | B | 0.0000 | |
| 234 | I | B | 0.0000 | |
| 235 | F | B | 0.0000 | |
| 236 | S | B | 0.0000 | |
| 237 | D | B | 0.0000 | |
| 238 | L | B | 0.0000 | |
| 239 | D | B | -0.1277 | |
| 240 | Y | B | 0.0000 | |
| 241 | M | B | 0.0000 | |
| 242 | G | B | 0.0000 | |
| 243 | M | B | 0.7284 | |
| 244 | S | B | 0.0000 | |
| 245 | S | B | -0.0334 | |
| 246 | G | B | -0.7308 | |
| 247 | F | B | 0.0000 | |
| 248 | Y | B | 0.0000 | |
| 249 | K | B | -0.5193 | |
| 250 | N | B | 0.0000 | |
| 251 | V | B | 0.0000 | |
| 252 | V | B | 0.0000 | |
| 253 | K | B | -0.6886 | |
| 254 | I | B | 0.0000 | |
| 255 | Q | B | 0.0000 | |
| 256 | K | B | -0.5693 | |
| 257 | R | B | -1.2847 | mutated: HR257B |
| 258 | V | B | 0.0000 | |
| 259 | T | B | -1.1512 | |
| 260 | F | B | 0.0000 | |
| 261 | N | B | -1.8691 | |
| 262 | Q | B | -1.4592 | |
| 263 | V | B | 0.0000 | |
| 264 | K | B | -1.9957 | |
| 265 | G | B | -1.1999 | |
| 266 | I | B | -0.4913 | |
| 267 | F | B | 0.0000 | |
| 268 | G | B | -1.0617 | |
| 269 | F | B | 0.0000 | |
| 270 | T | B | -1.3210 | |
| 271 | D | B | -2.1342 | |
| 272 | S | B | -1.2073 | |
| 273 | D | B | -0.9792 | |
| 274 | C | B | -0.7352 | |
| 275 | I | B | 0.0000 | |
| 276 | G | B | 0.0000 | |
| 277 | K | B | -0.3087 | |
| 278 | I | B | 0.0000 | |
| 279 | S | B | 0.0000 | |
| 280 | F | B | 0.0000 | |
| 281 | P | B | 0.0000 | |
| 282 | A | B | 0.0000 | |
| 283 | I | B | 0.0000 | |
| 284 | Q | B | 0.0000 | |
| 285 | A | B | 0.0000 | |
| 286 | A | B | 0.0000 | |
| 287 | P | B | 0.0000 | |
| 288 | S | B | 0.0000 | |
| 289 | F | B | 0.0000 | |
| 290 | S | B | 0.0000 | |
| 291 | N | B | -1.7182 | |
| 292 | S | B | 0.0000 | |
| 293 | F | B | 0.0000 | |
| 294 | P | B | -1.9515 | |
| 295 | Q | B | -1.6416 | |
| 296 | I | B | 0.0000 | |
| 297 | F | B | 0.0000 | |
| 298 | R | B | -3.5373 | |
| 299 | D | B | -3.3427 | |
| 300 | R | B | -2.6358 | |
| 301 | T | B | -1.9279 | |
| 302 | D | B | -2.5177 | |
| 303 | I | B | 0.0000 | |
| 304 | Q | B | -1.1528 | |
| 305 | C | B | 0.0000 | |
| 306 | L | B | 0.0000 | |
| 307 | I | B | 0.0000 | |
| 308 | P | B | 0.0000 | |
| 309 | C | B | 0.0000 | |
| 310 | A | B | -0.0999 | |
| 311 | I | B | 0.0000 | |
| 312 | D | B | 0.0026 | |
| 313 | Q | B | -0.4702 | |
| 314 | D | B | 0.0000 | |
| 315 | P | B | 0.0000 | |
| 316 | Y | B | 0.0000 | |
| 317 | F | B | 0.0000 | |
| 318 | R | B | -1.2378 | |
| 319 | M | B | 0.0000 | |
| 320 | T | B | 0.0000 | |
| 321 | R | B | -1.8429 | |
| 322 | D | B | -2.5830 | |
| 323 | V | B | 0.0000 | |
| 324 | A | B | 0.0000 | |
| 325 | P | B | -1.8123 | |
| 326 | R | B | -2.4355 | |
| 327 | I | B | -1.2610 | |
| 328 | G | B | -1.2862 | |
| 329 | Y | B | -1.1489 | |
| 330 | P | B | -1.0572 | |
| 331 | K | B | -1.7072 | |
| 332 | P | B | 0.0000 | |
| 333 | A | B | 0.0000 | |
| 334 | L | B | 0.0000 | |
| 335 | L | B | 0.0000 | |
| 336 | H | B | 0.0000 | |
| 337 | S | B | 0.0000 | |
| 338 | T | B | -0.0569 | |
| 339 | F | B | 0.3152 | |
| 340 | F | B | 0.0000 | |
| 341 | P | B | -0.3976 | |
| 342 | A | B | 0.0000 | |
| 343 | L | B | 0.0000 | |
| 344 | Q | B | -0.8186 | |
| 345 | G | B | 0.0000 | |
| 346 | A | B | -1.2213 | |
| 347 | Q | B | -2.0203 | |
| 348 | T | B | -1.4468 | |
| 349 | K | B | -1.8596 | |
| 350 | M | B | -0.9947 | |
| 351 | S | B | -0.8382 | |
| 352 | A | B | -0.8145 | |
| 353 | S | B | -0.7877 | |
| 354 | D | B | -1.4438 | |
| 355 | P | B | -0.9719 | |
| 356 | N | B | -1.3829 | |
| 357 | S | B | 0.0000 | |
| 358 | S | B | 0.0000 | |
| 359 | I | B | 0.0000 | |
| 360 | F | B | -0.0587 | |
| 361 | L | B | 0.0000 | |
| 362 | T | B | -0.3214 | |
| 363 | D | B | 0.0000 | |
| 364 | T | B | -1.0229 | |
| 365 | A | B | -1.5892 | |
| 366 | K | B | -2.4145 | |
| 367 | Q | B | -1.9747 | |
| 368 | I | B | 0.0000 | |
| 369 | K | B | -2.8075 | |
| 370 | T | B | -2.0609 | |
| 371 | K | B | 0.0000 | |
| 372 | V | B | 0.0000 | |
| 373 | N | B | -2.1620 | |
| 374 | K | B | -2.3143 | |
| 375 | H | B | -1.2716 | |
| 376 | A | B | 0.0000 | |
| 377 | F | B | 0.4457 | |
| 378 | S | B | -0.2889 | |
| 379 | G | B | 0.0000 | |
| 380 | G | B | -0.9242 | |
| 381 | R | B | -2.3731 | |
| 382 | D | B | -2.4703 | |
| 383 | T | B | -1.4484 | |
| 384 | I | B | -0.1797 | |
| 385 | E | B | -2.0554 | |
| 386 | E | B | -1.9672 | |
| 387 | H | B | 0.0000 | |
| 388 | R | B | -1.5640 | |
| 389 | Q | B | -1.4150 | |
| 390 | F | B | 0.2271 | |
| 391 | G | B | 0.0000 | |
| 392 | G | B | 0.0000 | |
| 393 | N | B | -1.3917 | |
| 394 | C | B | -1.6539 | |
| 395 | D | B | -2.3506 | |
| 396 | V | B | -1.1902 | |
| 397 | D | B | 0.0000 | |
| 398 | V | B | 0.0000 | |
| 399 | S | B | 0.0000 | |
| 400 | F | B | 0.0000 | |
| 401 | M | B | -0.1579 | |
| 402 | Y | B | 0.0000 | |
| 403 | L | B | 0.0000 | |
| 404 | T | B | -0.7651 | |
| 405 | F | B | 0.0000 | |
| 406 | F | B | 0.0000 | |
| 407 | L | B | 0.0000 | |
| 408 | E | B | -2.9315 | |
| 409 | D | B | -3.3294 | |
| 410 | D | B | -3.2436 | |
| 411 | D | B | -3.7983 | |
| 412 | K | B | -3.6875 | |
| 413 | L | B | 0.0000 | |
| 414 | E | B | -3.2347 | |
| 415 | Q | B | -3.2638 | |
| 416 | I | B | 0.0000 | |
| 417 | R | B | -2.7251 | |
| 418 | K | B | -2.7331 | |
| 419 | D | B | -1.7046 | |
| 420 | Y | B | 0.0000 | |
| 421 | T | B | -1.1036 | |
| 422 | S | B | -0.8845 | |
| 423 | G | B | 0.0000 | |
| 424 | A | B | -0.5996 | |
| 425 | M | B | -0.8292 | |
| 426 | L | B | -0.3691 | |
| 427 | T | B | -0.6536 | |
| 428 | G | B | -1.2358 | |
| 429 | E | B | -1.6752 | |
| 430 | L | B | 0.0000 | |
| 431 | K | B | -1.8060 | |
| 432 | K | B | -2.5852 | |
| 433 | A | B | -1.5858 | |
| 434 | L | B | 0.0000 | |
| 435 | I | B | 0.0000 | |
| 436 | E | B | -2.2892 | |
| 437 | V | B | -1.0749 | |
| 438 | L | B | 0.0000 | |
| 439 | Q | B | -1.4490 | |
| 440 | P | B | -1.0402 | |
| 441 | L | B | -0.6305 | |
| 442 | I | B | 0.0000 | |
| 443 | A | B | -1.0765 | |
| 444 | E | B | -2.2079 | |
| 445 | H | B | 0.0000 | |
| 446 | Q | B | -1.7404 | |
| 447 | A | B | -2.0158 | |
| 448 | R | B | -2.4738 | |
| 449 | R | B | -2.4647 | |
| 450 | K | B | -3.1534 | |
| 451 | E | B | -3.0315 | |
| 452 | V | B | -2.0967 | |
| 453 | T | B | -2.4934 | |
| 454 | D | B | -3.3138 | |
| 455 | E | B | -3.2744 | |
| 456 | I | B | -1.8792 | |
| 457 | V | B | 0.0000 | |
| 458 | K | B | -3.1863 | |
| 459 | E | B | -2.6458 | |
| 460 | F | B | 0.0000 | |
| 461 | M | B | -1.0317 | |
| 462 | T | B | -1.0575 | |
| 463 | P | B | -0.8193 | |
| 464 | R | B | -1.5075 | |
| 465 | K | B | -2.5842 | |
| 466 | L | B | 0.0000 | |
| 467 | S | B | -1.3213 | |
| 468 | F | B | -1.4830 | |
| 469 | D | B | -2.4140 | |
| 470 | F | B | -1.8512 | |
| 471 | Q | B | -2.1560 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine