Project name: 6d40896c5ab82af

Chain sequence(s)	H: QVQLQDSGGGLVQAGGSLRLSCEASGSIFSISAMGWYRQAPGKQRELVAVITTDGSTNYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTDVYYCGASPRALKWYWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:09)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:09)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:09)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:09)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:09)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:32)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:33)

• Minimal score value: -3.0028
• Maximal score value: 2.0318
• Average score: -0.9009
• Total score value: -104.5039

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.6183
2	V	H	-1.0912
3	Q	H	-1.8807
4	L	H	-1.7808
5	Q	H	-2.3594
6	D	H	-1.7524
7	S	H	-1.5019
9	G	H	-1.3072
10	G	H	-0.8913
11	G	H	0.1265
12	L	H	1.0909
13	V	H	0.0998
14	Q	H	-1.2271
15	A	H	-1.3992
16	G	H	-1.4056
17	G	H	-0.9857
18	S	H	-1.3906
19	L	H	-1.1335
20	R	H	-2.3696
21	L	H	0.0000
22	S	H	-1.3414
23	C	H	0.0000
24	E	H	-2.5438
25	A	H	-1.6798
26	S	H	-1.3929
27	G	H	-0.7684
29	S	H	-0.1365
30	I	H	0.8626
31	F	H	2.0318
32	S	H	0.7368
33	I	H	0.2139
39	S	H	-0.4380
40	A	H	0.0000
41	M	H	0.0000
42	G	H	0.0000
43	W	H	0.0000
44	Y	H	-0.1289
45	R	H	0.0000
46	Q	H	-1.8011
47	A	H	-1.6469
48	P	H	-1.2166
49	G	H	-1.7259
50	K	H	-3.0028
51	Q	H	-2.7926
52	R	H	-2.0195
53	E	H	-1.7297
54	L	H	-0.1942
55	V	H	0.0000
56	A	H	0.0000
57	V	H	-0.2874
58	I	H	0.0000
59	T	H	-1.2368
60	T	H	-1.2505
65	D	H	-2.0685
66	G	H	-1.5281
67	S	H	-1.1289
68	T	H	-0.9564
69	N	H	-1.4769
70	Y	H	-1.1515
71	A	H	-1.4294
72	D	H	-2.5566
73	S	H	-1.8012
74	V	H	0.0000
75	K	H	-2.7581
76	G	H	-1.8727
77	R	H	-1.7435
78	F	H	0.0000
79	T	H	-1.2179
80	I	H	0.0000
81	S	H	-0.7153
82	R	H	-1.4323
83	D	H	-2.1019
84	N	H	-2.2965
85	A	H	-1.5916
86	K	H	-2.3775
87	N	H	-2.0848
88	T	H	0.0000
89	V	H	0.0000
90	Y	H	-0.8602
91	L	H	0.0000
92	Q	H	-1.8170
93	M	H	0.0000
94	N	H	-2.1770
95	S	H	-1.4603
96	L	H	0.0000
97	K	H	-2.1437
98	P	H	-1.7911
99	E	H	-2.2431
100	D	H	0.0000
101	T	H	-0.8655
102	D	H	0.0000
103	V	H	-0.5326
104	Y	H	0.0000
105	Y	H	-0.3219
106	C	H	0.0000
107	G	H	0.0000
108	A	H	0.0000
109	S	H	0.0000
110	P	H	-0.6082
111	R	H	-1.5666
112	A	H	-0.5396
135	L	H	0.3993
136	K	H	-0.7738
137	W	H	0.2244
138	Y	H	0.3458
139	W	H	0.1107
140	G	H	-0.9628
141	Q	H	-1.3675
142	G	H	-1.0881
143	T	H	-1.0661
144	Q	H	-1.1030
145	V	H	0.0000
146	T	H	-0.2874
147	V	H	0.0000
148	S	H	-0.6178
149	S	H	-0.8353