| Chain sequence(s) |
A: EIVLTQSPATLSLSPGERATLSCRASKGVSTSGYSYLHWYQQKPGQAPRLLIYLASYLESGVPARFSGSGSGTDFTLTISSLEPEDFAVYYCQHSRDLPLTFGGGTKVEIKGQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
B: QVQLVQSGVEVKKPGASVKVSCKASGYTFTNYYMYWVRQAPGQGLEWMGGINPSNGGTNFNEKFKNRVTLTTDSSTTTAYMELKSLQFDDTAVYYCARRDYRFDMGFDYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVCTLPPSRDELTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGGGGGSGGGGSGGGGSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPELTAMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSDSIISTLT input PDB |
| Selected Chain(s) | A,B |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | LA483B |
| Energy difference between WT (input) and mutated protein (by FoldX) | 0.336303 kcal/mol |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with all chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:00)
[INFO] FoldX: Building mutant model (00:04:13)
[INFO] FoldX: Starting FoldX energy minimalization (00:04:26)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:08:12)
[INFO] Main: Simulation completed successfully. (00:08:20)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | E | A | -1.6369 | |
| 2 | I | A | -0.7768 | |
| 3 | V | A | 0.8250 | |
| 4 | L | A | 0.0000 | |
| 5 | T | A | -0.2196 | |
| 6 | Q | A | 0.0000 | |
| 7 | S | A | -0.3842 | |
| 8 | P | A | -0.2103 | |
| 9 | A | A | -0.1937 | |
| 10 | T | A | -0.2071 | |
| 11 | L | A | -0.2065 | |
| 12 | S | A | -0.7475 | |
| 13 | L | A | -1.1601 | |
| 14 | S | A | -1.5354 | |
| 15 | P | A | -1.7434 | |
| 16 | G | A | -1.6743 | |
| 17 | E | A | -2.2257 | |
| 18 | R | A | -2.5287 | |
| 19 | A | A | 0.0000 | |
| 20 | T | A | -0.6272 | |
| 21 | L | A | 0.0000 | |
| 22 | S | A | -0.7360 | |
| 23 | C | A | 0.0000 | |
| 24 | R | A | -1.6198 | |
| 25 | A | A | 0.0000 | |
| 26 | S | A | -1.0499 | |
| 27 | K | A | -2.1970 | |
| 28 | G | A | -1.6403 | |
| 29 | V | A | 0.0000 | |
| 30 | S | A | -0.7075 | |
| 31 | T | A | -0.4396 | |
| 32 | S | A | -0.4228 | |
| 33 | G | A | -0.7773 | |
| 34 | Y | A | -0.3052 | |
| 35 | S | A | 0.0000 | |
| 36 | Y | A | -0.4295 | |
| 37 | L | A | 0.0000 | |
| 38 | H | A | 0.0000 | |
| 39 | W | A | 0.0000 | |
| 40 | Y | A | 0.0000 | |
| 41 | Q | A | -0.6131 | |
| 42 | Q | A | 0.0000 | |
| 43 | K | A | -1.5906 | |
| 44 | P | A | -1.2060 | |
| 45 | G | A | -1.4450 | |
| 46 | Q | A | -2.1134 | |
| 47 | A | A | -1.3410 | |
| 48 | P | A | 0.0000 | |
| 49 | R | A | -1.1225 | |
| 50 | L | A | 0.0000 | |
| 51 | L | A | 0.0000 | |
| 52 | I | A | 0.0000 | |
| 53 | Y | A | 0.0000 | |
| 54 | L | A | 0.0000 | |
| 55 | A | A | 0.0000 | |
| 56 | S | A | -0.1976 | |
| 57 | Y | A | 0.1257 | |
| 58 | L | A | 0.0965 | |
| 59 | E | A | 0.0000 | |
| 60 | S | A | -0.4447 | |
| 61 | G | A | -0.5997 | |
| 62 | V | A | 0.0000 | |
| 63 | P | A | -0.3079 | |
| 64 | A | A | -0.2086 | |
| 65 | R | A | -0.7327 | |
| 66 | F | A | 0.0000 | |
| 67 | S | A | -0.2665 | |
| 68 | G | A | -0.2874 | |
| 69 | S | A | -0.7758 | |
| 70 | G | A | -1.2777 | |
| 71 | S | A | -1.1700 | |
| 72 | G | A | -1.2987 | |
| 73 | T | A | -1.9188 | |
| 74 | D | A | -2.5973 | |
| 75 | F | A | 0.0000 | |
| 76 | T | A | -0.8177 | |
| 77 | L | A | 0.0000 | |
| 78 | T | A | -0.6201 | |
| 79 | I | A | 0.0000 | |
| 80 | S | A | -1.3130 | |
| 81 | S | A | -1.6690 | |
| 82 | L | A | 0.0000 | |
| 83 | E | A | -2.3538 | |
| 84 | P | A | -1.8031 | |
| 85 | E | A | -2.3642 | |
| 86 | D | A | 0.0000 | |
| 87 | F | A | -0.8793 | |
| 88 | A | A | 0.0000 | |
| 89 | V | A | -0.0849 | |
| 90 | Y | A | 0.0000 | |
| 91 | Y | A | 0.0000 | |
| 92 | C | A | 0.0000 | |
| 93 | Q | A | 0.0000 | |
| 94 | H | A | 0.0000 | |
| 95 | S | A | -0.7927 | |
| 96 | R | A | -1.7685 | |
| 97 | D | A | -2.0969 | |
| 98 | L | A | -1.0599 | |
| 99 | P | A | -1.1444 | |
| 100 | L | A | 0.0000 | |
| 101 | T | A | -0.1663 | |
| 102 | F | A | 0.2630 | |
| 103 | G | A | 0.0000 | |
| 104 | G | A | -0.5568 | |
| 105 | G | A | -0.4932 | |
| 106 | T | A | 0.0000 | |
| 107 | K | A | -0.5375 | |
| 108 | V | A | 0.0000 | |
| 109 | E | A | -0.7553 | |
| 110 | I | A | -0.9664 | |
| 111 | K | A | -1.8692 | |
| 112 | G | A | -1.6921 | |
| 113 | Q | A | -1.6597 | |
| 114 | P | A | -1.7337 | |
| 115 | K | A | -2.5980 | |
| 116 | A | A | -1.8610 | |
| 117 | N | A | -1.9361 | |
| 118 | P | A | 0.0000 | |
| 119 | T | A | -0.4381 | |
| 120 | V | A | 0.0000 | |
| 121 | T | A | -0.6333 | |
| 122 | L | A | 0.0000 | |
| 123 | F | A | 0.0000 | |
| 124 | P | A | -0.2321 | |
| 125 | P | A | 0.0000 | |
| 126 | S | A | -0.7566 | |
| 127 | S | A | -1.2450 | |
| 128 | E | A | -1.8679 | |
| 129 | E | A | 0.0000 | |
| 130 | L | A | -1.8952 | |
| 131 | Q | A | -2.1483 | |
| 132 | A | A | -1.8555 | |
| 133 | N | A | -2.4337 | |
| 134 | K | A | -2.1432 | |
| 135 | A | A | 0.0000 | |
| 136 | T | A | 0.0000 | |
| 137 | L | A | 0.0000 | |
| 138 | V | A | 0.0000 | |
| 139 | C | A | 0.0000 | |
| 140 | L | A | 0.0000 | |
| 141 | I | A | 0.0000 | |
| 142 | S | A | -0.6059 | |
| 143 | D | A | -1.3722 | |
| 144 | F | A | 0.0000 | |
| 145 | Y | A | -1.4413 | |
| 146 | P | A | -1.3221 | |
| 147 | G | A | -0.8955 | |
| 148 | A | A | -0.4282 | |
| 149 | V | A | -0.3982 | |
| 150 | T | A | -0.0920 | |
| 151 | V | A | 0.0761 | |
| 152 | A | A | -0.4434 | |
| 153 | W | A | 0.0000 | |
| 154 | K | A | -1.1931 | |
| 155 | A | A | 0.0000 | |
| 156 | D | A | -1.5740 | |
| 157 | G | A | -1.2015 | |
| 158 | S | A | -0.7867 | |
| 159 | P | A | -0.9190 | |
| 160 | V | A | -0.8776 | |
| 161 | K | A | -1.6511 | |
| 162 | A | A | -0.8136 | |
| 163 | G | A | -0.6629 | |
| 164 | V | A | -0.4990 | |
| 165 | E | A | -0.3273 | |
| 166 | T | A | -0.3210 | |
| 167 | T | A | 0.0000 | |
| 168 | K | A | -1.7845 | |
| 169 | P | A | -1.0629 | |
| 170 | S | A | -1.0388 | |
| 171 | K | A | -1.4777 | |
| 172 | Q | A | -1.3161 | |
| 173 | S | A | -1.2454 | |
| 174 | N | A | -1.8787 | |
| 175 | N | A | -1.5761 | |
| 176 | K | A | -1.7074 | |
| 177 | Y | A | -1.0109 | |
| 178 | A | A | 0.0000 | |
| 179 | A | A | 0.0000 | |
| 180 | S | A | 0.0000 | |
| 181 | S | A | 0.0000 | |
| 182 | Y | A | 0.0000 | |
| 183 | L | A | 0.0000 | |
| 184 | S | A | -0.4219 | |
| 185 | L | A | -0.9955 | |
| 186 | T | A | -1.6806 | |
| 187 | P | A | -2.3348 | |
| 188 | E | A | -3.1080 | |
| 189 | Q | A | -2.2441 | |
| 190 | W | A | 0.0000 | |
| 191 | K | A | -3.0732 | |
| 192 | S | A | -2.3638 | |
| 193 | H | A | -2.4083 | |
| 194 | R | A | -2.7894 | |
| 195 | S | A | -1.8379 | |
| 196 | Y | A | 0.0000 | |
| 197 | S | A | -1.0691 | |
| 198 | C | A | 0.0000 | |
| 199 | Q | A | -1.0338 | |
| 200 | V | A | 0.0000 | |
| 201 | T | A | -0.8508 | |
| 202 | H | A | 0.0000 | |
| 203 | E | A | -2.4828 | |
| 204 | G | A | -1.3997 | |
| 205 | S | A | -1.0422 | |
| 206 | T | A | -0.9557 | |
| 207 | V | A | -0.9974 | |
| 208 | E | A | -2.1149 | |
| 209 | K | A | -1.8089 | |
| 210 | T | A | -1.2141 | |
| 211 | V | A | 0.0000 | |
| 212 | A | A | 0.0000 | |
| 213 | P | A | 0.0000 | |
| 214 | T | A | -1.5323 | |
| 215 | E | A | -1.8602 | |
| 216 | C | A | -0.8492 | |
| 217 | S | A | -0.6977 | |
| 1 | Q | B | -1.5346 | |
| 2 | V | B | -1.0176 | |
| 3 | Q | B | -1.4026 | |
| 4 | L | B | 0.0000 | |
| 5 | V | B | -0.1765 | |
| 6 | Q | B | 0.0000 | |
| 7 | S | B | -0.5220 | |
| 8 | G | B | -0.2720 | |
| 9 | V | B | 0.3284 | |
| 10 | E | B | -0.4638 | |
| 11 | V | B | -0.2963 | |
| 12 | K | B | -1.1979 | |
| 13 | K | B | -1.9678 | |
| 14 | P | B | -1.5165 | |
| 15 | G | B | -1.3366 | |
| 16 | A | B | -1.3246 | |
| 17 | S | B | -1.6096 | |
| 18 | V | B | 0.0000 | |
| 19 | K | B | -1.9689 | |
| 20 | V | B | 0.0000 | |
| 21 | S | B | -0.5363 | |
| 22 | C | B | 0.0000 | |
| 23 | K | B | -1.0940 | |
| 24 | A | B | 0.0000 | |
| 25 | S | B | -0.8444 | |
| 26 | G | B | -0.8447 | |
| 27 | Y | B | 0.0000 | |
| 28 | T | B | 0.0000 | |
| 29 | F | B | 0.0000 | |
| 30 | T | B | -0.4276 | |
| 31 | N | B | 0.0685 | |
| 32 | Y | B | 0.0000 | |
| 33 | Y | B | 0.3738 | |
| 34 | M | B | 0.0000 | |
| 35 | Y | B | 0.0699 | |
| 36 | W | B | 0.0000 | |
| 37 | V | B | 0.0000 | |
| 38 | R | B | 0.0000 | |
| 39 | Q | B | -0.5867 | |
| 40 | A | B | -1.0175 | |
| 41 | P | B | -1.0318 | |
| 42 | G | B | -1.2161 | |
| 43 | Q | B | -1.7359 | |
| 44 | G | B | -1.0549 | |
| 45 | L | B | 0.0000 | |
| 46 | E | B | -0.5918 | |
| 47 | W | B | 0.0000 | |
| 48 | M | B | 0.0000 | |
| 49 | G | B | 0.0000 | |
| 50 | G | B | 0.0000 | |
| 51 | I | B | 0.0000 | |
| 52 | N | B | 0.0000 | |
| 53 | P | B | -0.8867 | |
| 54 | S | B | -1.1209 | |
| 55 | N | B | -1.6667 | |
| 56 | G | B | -1.2949 | |
| 57 | G | B | -1.1669 | |
| 58 | T | B | -0.9332 | |
| 59 | N | B | -1.4712 | |
| 60 | F | B | -1.5778 | |
| 61 | N | B | -2.1112 | |
| 62 | E | B | -3.4674 | |
| 63 | K | B | -3.2407 | |
| 64 | F | B | 0.0000 | |
| 65 | K | B | -3.4379 | |
| 66 | N | B | -2.9046 | |
| 67 | R | B | -2.3548 | |
| 68 | V | B | 0.0000 | |
| 69 | T | B | -0.9486 | |
| 70 | L | B | 0.0000 | |
| 71 | T | B | -0.2938 | |
| 72 | T | B | -0.7868 | |
| 73 | D | B | -1.1243 | |
| 74 | S | B | -0.7698 | |
| 75 | S | B | -0.5852 | |
| 76 | T | B | -0.6741 | |
| 77 | T | B | -0.7568 | |
| 78 | T | B | 0.0000 | |
| 79 | A | B | 0.0000 | |
| 80 | Y | B | -0.3778 | |
| 81 | M | B | 0.0000 | |
| 82 | E | B | -1.2399 | |
| 83 | L | B | 0.0000 | |
| 84 | K | B | -2.0837 | |
| 85 | S | B | -1.6179 | |
| 86 | L | B | 0.0000 | |
| 87 | Q | B | -1.3754 | |
| 88 | F | B | 0.1618 | |
| 89 | D | B | -1.2470 | |
| 90 | D | B | 0.0000 | |
| 91 | T | B | -0.2778 | |
| 92 | A | B | 0.0000 | |
| 93 | V | B | 0.2195 | |
| 94 | Y | B | 0.0000 | |
| 95 | Y | B | 0.0000 | |
| 96 | C | B | 0.0000 | |
| 97 | A | B | 0.0000 | |
| 98 | R | B | 0.0000 | |
| 99 | R | B | 0.0000 | |
| 100 | D | B | 0.0000 | |
| 101 | Y | B | 1.2878 | |
| 102 | R | B | 0.3116 | |
| 103 | F | B | 0.4072 | |
| 104 | D | B | 0.1627 | |
| 105 | M | B | 0.0000 | |
| 106 | G | B | 0.0000 | |
| 107 | F | B | 0.0000 | |
| 108 | D | B | -0.1664 | |
| 109 | Y | B | -0.2058 | |
| 110 | W | B | -0.3964 | |
| 111 | G | B | 0.0000 | |
| 112 | Q | B | -1.4176 | |
| 113 | G | B | -0.6106 | |
| 114 | T | B | 0.0000 | |
| 115 | T | B | -0.0136 | |
| 116 | V | B | 0.0000 | |
| 117 | T | B | -0.2747 | |
| 118 | V | B | 0.0000 | |
| 119 | S | B | -0.6262 | |
| 120 | S | B | -0.6291 | |
| 121 | A | B | -0.6056 | |
| 122 | S | B | -0.6427 | |
| 123 | T | B | -0.4297 | |
| 124 | K | B | -0.6656 | |
| 125 | G | B | 0.0000 | |
| 126 | P | B | 0.0000 | |
| 127 | S | B | -0.1939 | |
| 128 | V | B | 0.0000 | |
| 129 | F | B | 0.0000 | |
| 130 | P | B | 0.0000 | |
| 131 | L | B | 0.0000 | |
| 132 | A | B | -1.1354 | |
| 133 | P | B | 0.0000 | |
| 134 | S | B | -1.3963 | |
| 135 | S | B | -1.2262 | |
| 136 | K | B | -1.9968 | |
| 137 | S | B | -1.1025 | |
| 138 | T | B | -1.0535 | |
| 139 | S | B | -0.9789 | |
| 140 | G | B | -0.8457 | |
| 141 | G | B | -0.9002 | |
| 142 | T | B | -0.6194 | |
| 143 | A | B | 0.0000 | |
| 144 | A | B | -0.3142 | |
| 145 | L | B | 0.0000 | |
| 146 | G | B | 0.0000 | |
| 147 | C | B | 0.0000 | |
| 148 | L | B | 0.0000 | |
| 149 | V | B | 0.0000 | |
| 150 | K | B | 0.0000 | |
| 151 | D | B | -0.0759 | |
| 152 | Y | B | 0.0000 | |
| 153 | F | B | 0.0000 | |
| 154 | P | B | 0.0000 | |
| 155 | E | B | -0.6912 | |
| 156 | P | B | -0.7860 | |
| 157 | V | B | -0.6597 | |
| 158 | T | B | -0.5159 | |
| 159 | V | B | -0.2100 | |
| 160 | S | B | -0.2712 | |
| 161 | W | B | 0.0000 | |
| 162 | N | B | -0.5695 | |
| 163 | S | B | -0.5341 | |
| 164 | G | B | -0.4248 | |
| 165 | A | B | -0.4419 | |
| 166 | L | B | 0.0153 | |
| 167 | T | B | -0.1867 | |
| 168 | S | B | -0.2700 | |
| 169 | G | B | -0.3438 | |
| 170 | V | B | 0.1402 | |
| 171 | H | B | -0.1782 | |
| 172 | T | B | -0.0420 | |
| 173 | F | B | 0.0000 | |
| 174 | P | B | -0.2465 | |
| 175 | A | B | 0.0488 | |
| 176 | V | B | 0.0000 | |
| 177 | L | B | 1.1501 | |
| 178 | Q | B | 0.2904 | |
| 179 | S | B | -0.1177 | |
| 180 | S | B | -0.1367 | |
| 181 | G | B | 0.0633 | |
| 182 | L | B | 0.1894 | |
| 183 | Y | B | 0.4092 | |
| 184 | S | B | 0.0000 | |
| 185 | L | B | 0.0000 | |
| 186 | S | B | 0.0000 | |
| 187 | S | B | 0.0000 | |
| 188 | V | B | 0.1511 | |
| 189 | V | B | 0.0000 | |
| 190 | T | B | -0.2119 | |
| 191 | V | B | 0.0000 | |
| 192 | P | B | -0.5951 | |
| 193 | S | B | -0.5788 | |
| 194 | S | B | -0.5584 | |
| 195 | S | B | -0.5278 | |
| 196 | L | B | -0.7240 | |
| 197 | G | B | -0.9247 | |
| 198 | T | B | -0.6452 | |
| 199 | Q | B | -1.0643 | |
| 200 | T | B | -0.9543 | |
| 201 | Y | B | 0.0000 | |
| 202 | I | B | -0.8852 | |
| 203 | C | B | 0.0000 | |
| 204 | N | B | -1.0989 | |
| 205 | V | B | 0.0000 | |
| 206 | N | B | -1.6080 | |
| 207 | H | B | 0.0000 | |
| 208 | K | B | -2.6271 | |
| 209 | P | B | -1.4378 | |
| 210 | S | B | -1.5765 | |
| 211 | N | B | -2.3789 | |
| 212 | T | B | 0.0000 | |
| 213 | K | B | -2.0657 | |
| 214 | V | B | -1.1986 | |
| 215 | D | B | -1.7602 | |
| 216 | K | B | -1.6531 | |
| 217 | K | B | -1.9969 | |
| 218 | V | B | 0.0000 | |
| 219 | E | B | -2.6567 | |
| 220 | P | B | -1.6600 | |
| 221 | K | B | -2.0372 | |
| 222 | S | B | -1.6832 | |
| 223 | C | B | -1.4003 | |
| 224 | D | B | -2.7690 | |
| 225 | K | B | -2.7115 | |
| 226 | T | B | -1.7651 | |
| 227 | H | B | -1.6869 | |
| 228 | T | B | -0.7117 | |
| 229 | C | B | 0.3244 | |
| 230 | P | B | -0.0091 | |
| 231 | P | B | 0.0587 | |
| 232 | C | B | 0.4911 | |
| 233 | P | B | -0.3599 | |
| 234 | A | B | -0.5442 | |
| 235 | P | B | -1.0300 | |
| 236 | E | B | -1.9814 | |
| 237 | A | B | -1.0449 | |
| 238 | A | B | -0.8982 | |
| 239 | G | B | -1.1099 | |
| 240 | G | B | -0.9866 | |
| 241 | P | B | 0.0000 | |
| 242 | S | B | -0.3369 | |
| 243 | V | B | 0.0000 | |
| 244 | F | B | 1.1125 | |
| 245 | L | B | 0.9088 | |
| 246 | F | B | 1.1007 | |
| 247 | P | B | -0.1535 | |
| 248 | P | B | 0.0000 | |
| 249 | K | B | -2.1869 | |
| 250 | P | B | -1.4015 | |
| 251 | K | B | -1.2684 | |
| 252 | D | B | 0.0000 | |
| 253 | T | B | 0.0000 | |
| 254 | L | B | 0.0000 | |
| 255 | M | B | 0.3027 | |
| 256 | I | B | 1.4691 | |
| 257 | S | B | 0.1229 | |
| 258 | R | B | -1.1080 | |
| 259 | T | B | -0.7002 | |
| 260 | P | B | 0.0000 | |
| 261 | E | B | -1.2400 | |
| 262 | V | B | 0.0000 | |
| 263 | T | B | 0.1908 | |
| 264 | C | B | 0.0000 | |
| 265 | V | B | 0.8188 | |
| 266 | V | B | 0.0000 | |
| 267 | V | B | -0.6481 | |
| 268 | D | B | -1.4176 | |
| 269 | V | B | 0.0000 | |
| 270 | S | B | -2.3759 | |
| 271 | H | B | -2.7032 | |
| 272 | E | B | -3.0341 | |
| 273 | D | B | -2.7224 | |
| 274 | P | B | -2.9231 | |
| 275 | E | B | -3.1351 | |
| 276 | V | B | -1.9897 | |
| 277 | K | B | -2.2372 | |
| 278 | F | B | -1.3432 | |
| 279 | N | B | -1.0971 | |
| 280 | W | B | 0.0000 | |
| 281 | Y | B | -0.5738 | |
| 282 | V | B | -0.8083 | |
| 283 | D | B | -2.0587 | |
| 284 | G | B | -0.8422 | |
| 285 | V | B | 0.6076 | |
| 286 | E | B | -0.6416 | |
| 287 | V | B | -0.5148 | |
| 288 | H | B | -1.8734 | |
| 289 | N | B | -2.1722 | |
| 290 | A | B | -1.8796 | |
| 291 | K | B | -2.3580 | |
| 292 | T | B | -1.7601 | |
| 293 | K | B | -1.8774 | |
| 294 | P | B | -1.9904 | |
| 295 | R | B | -2.8944 | |
| 296 | E | B | -2.7632 | |
| 297 | E | B | -3.0016 | |
| 298 | Q | B | 0.0000 | |
| 299 | Y | B | -0.6543 | |
| 300 | N | B | -1.1669 | |
| 301 | S | B | -1.1963 | |
| 302 | T | B | -1.9416 | |
| 303 | Y | B | 0.0000 | |
| 304 | R | B | -1.6412 | |
| 305 | V | B | 0.0000 | |
| 306 | V | B | -0.6015 | |
| 307 | S | B | 0.0000 | |
| 308 | V | B | 0.0000 | |
| 309 | L | B | 0.0000 | |
| 310 | T | B | -0.7772 | |
| 311 | V | B | 0.0000 | |
| 312 | L | B | 0.3710 | |
| 313 | H | B | -0.2901 | |
| 314 | Q | B | -1.2766 | |
| 315 | D | B | -1.5649 | |
| 316 | W | B | 0.0000 | |
| 317 | L | B | -1.0379 | |
| 318 | N | B | -2.1051 | |
| 319 | G | B | -2.0707 | |
| 320 | K | B | -2.1344 | |
| 321 | E | B | -1.9663 | |
| 322 | Y | B | 0.0000 | |
| 323 | K | B | -1.4468 | |
| 324 | C | B | 0.0000 | |
| 325 | K | B | -1.4203 | |
| 326 | V | B | 0.0000 | |
| 327 | S | B | -1.4874 | |
| 328 | N | B | 0.0000 | |
| 329 | K | B | -2.5817 | |
| 330 | A | B | -1.4674 | |
| 331 | L | B | -0.8570 | |
| 332 | P | B | -0.6817 | |
| 333 | A | B | -0.4814 | |
| 334 | P | B | -1.0209 | |
| 335 | I | B | -0.9036 | |
| 336 | E | B | -1.7710 | |
| 337 | K | B | -1.0444 | |
| 338 | T | B | -0.8794 | |
| 339 | I | B | -0.1329 | |
| 340 | S | B | -1.1110 | |
| 341 | K | B | -1.2640 | |
| 342 | A | B | -1.1803 | |
| 343 | K | B | -2.3527 | |
| 344 | G | B | -1.9803 | |
| 345 | Q | B | -2.1321 | |
| 346 | P | B | -1.7730 | |
| 347 | R | B | -2.2049 | |
| 348 | E | B | -2.8361 | |
| 349 | P | B | 0.0000 | |
| 350 | Q | B | -1.7684 | |
| 351 | V | B | -0.9399 | |
| 352 | C | B | -0.1035 | |
| 353 | T | B | 0.0469 | |
| 354 | L | B | 0.6181 | |
| 355 | P | B | -0.0874 | |
| 356 | P | B | -0.9264 | |
| 357 | S | B | -1.6910 | |
| 358 | R | B | -3.0670 | |
| 359 | D | B | -3.1911 | |
| 360 | E | B | -2.8660 | |
| 361 | L | B | -2.3960 | |
| 362 | T | B | -2.2263 | |
| 363 | K | B | -3.3942 | |
| 364 | N | B | -2.9926 | |
| 365 | Q | B | -2.7116 | |
| 366 | V | B | 0.0000 | |
| 367 | S | B | -0.7997 | |
| 368 | L | B | 0.0000 | |
| 369 | S | B | 0.0000 | |
| 370 | C | B | 0.0000 | |
| 371 | A | B | 0.0502 | |
| 372 | V | B | 0.0000 | |
| 373 | K | B | -0.8435 | |
| 374 | G | B | -1.4377 | |
| 375 | F | B | 0.0000 | |
| 376 | Y | B | -1.0271 | |
| 377 | P | B | 0.0000 | |
| 378 | S | B | 0.0731 | |
| 379 | D | B | -1.0683 | |
| 380 | I | B | 0.0000 | |
| 381 | A | B | -0.6642 | |
| 382 | V | B | 0.0000 | |
| 383 | E | B | -1.3727 | |
| 384 | W | B | 0.0000 | |
| 385 | E | B | -1.7021 | |
| 386 | S | B | 0.0000 | |
| 387 | N | B | -1.8240 | |
| 388 | G | B | -1.7315 | |
| 389 | Q | B | -2.2370 | |
| 390 | P | B | -1.8787 | |
| 391 | E | B | 0.0000 | |
| 392 | N | B | -2.3116 | |
| 393 | N | B | -2.1841 | |
| 394 | Y | B | -2.0826 | |
| 395 | K | B | -2.5029 | |
| 396 | T | B | -1.2104 | |
| 397 | T | B | -0.3695 | |
| 398 | P | B | 0.1094 | |
| 399 | P | B | 0.7299 | |
| 400 | V | B | 1.7140 | |
| 401 | L | B | 1.3860 | |
| 402 | D | B | -0.5041 | |
| 403 | S | B | -1.0773 | |
| 404 | D | B | -2.0210 | |
| 405 | G | B | -0.7595 | |
| 406 | S | B | 0.0000 | |
| 407 | F | B | 0.4759 | |
| 408 | F | B | 0.7599 | |
| 409 | L | B | 0.0000 | |
| 410 | V | B | -0.0074 | |
| 411 | S | B | 0.0000 | |
| 412 | K | B | -1.9149 | |
| 413 | L | B | 0.0000 | |
| 414 | T | B | -1.5460 | |
| 415 | V | B | 0.0000 | |
| 416 | D | B | -2.6546 | |
| 417 | K | B | -2.8871 | |
| 418 | S | B | -2.0417 | |
| 419 | R | B | -1.8709 | |
| 420 | W | B | 0.0000 | |
| 421 | Q | B | -2.2892 | |
| 422 | Q | B | -1.9698 | |
| 423 | G | B | -1.0733 | |
| 424 | N | B | -0.7760 | |
| 425 | V | B | 0.2534 | |
| 426 | F | B | 0.0000 | |
| 427 | S | B | -1.1394 | |
| 428 | C | B | 0.0000 | |
| 429 | S | B | 0.0000 | |
| 430 | V | B | 0.0000 | |
| 431 | M | B | 0.0000 | |
| 432 | H | B | 0.0000 | |
| 433 | E | B | -1.0833 | |
| 434 | A | B | -1.4951 | |
| 435 | L | B | -1.5018 | |
| 436 | H | B | -1.7678 | |
| 437 | N | B | -1.6900 | |
| 438 | H | B | -1.2278 | |
| 439 | Y | B | -0.6017 | |
| 440 | T | B | -1.0906 | |
| 441 | Q | B | -1.6522 | |
| 442 | K | B | -1.5162 | |
| 443 | S | B | -0.6354 | |
| 444 | L | B | 0.0000 | |
| 445 | S | B | -0.0195 | |
| 446 | L | B | -0.3282 | |
| 447 | S | B | -0.4371 | |
| 448 | P | B | -0.8354 | |
| 449 | G | B | -0.9820 | |
| 450 | G | B | -1.2064 | |
| 451 | G | B | -1.2194 | |
| 452 | G | B | -1.1980 | |
| 453 | G | B | -1.1811 | |
| 454 | S | B | -1.0107 | |
| 455 | G | B | -1.1711 | |
| 456 | G | B | -1.1639 | |
| 457 | G | B | -1.1826 | |
| 458 | G | B | -1.1177 | |
| 459 | S | B | -1.0050 | |
| 460 | G | B | -1.1328 | |
| 461 | G | B | -1.1594 | |
| 462 | G | B | -1.1299 | |
| 463 | G | B | -0.9803 | |
| 464 | S | B | -0.7030 | |
| 465 | A | B | -0.3939 | |
| 466 | P | B | -0.4848 | |
| 467 | T | B | -0.5806 | |
| 468 | S | B | -0.9737 | |
| 469 | S | B | -1.3044 | |
| 470 | S | B | -1.3341 | |
| 471 | T | B | -1.2108 | |
| 472 | K | B | -1.9526 | |
| 473 | K | B | -2.3948 | |
| 474 | T | B | -1.4590 | |
| 475 | Q | B | -1.3431 | |
| 476 | L | B | -1.0011 | |
| 477 | Q | B | -1.1844 | |
| 478 | L | B | 0.0000 | |
| 479 | E | B | -1.6391 | |
| 480 | H | B | -1.4575 | |
| 481 | L | B | 0.0000 | |
| 482 | L | B | -0.7561 | |
| 483 | A | B | -0.5509 | mutated: LA483B |
| 484 | D | B | -0.6428 | |
| 485 | L | B | 0.0000 | |
| 486 | Q | B | -0.6823 | |
| 487 | M | B | -0.2366 | |
| 488 | I | B | 0.0000 | |
| 489 | L | B | -1.0577 | |
| 490 | N | B | -1.6353 | |
| 491 | G | B | 0.0000 | |
| 492 | I | B | 0.0000 | |
| 493 | N | B | -2.3284 | |
| 494 | N | B | -2.5573 | |
| 495 | Y | B | -2.4062 | |
| 496 | K | B | -2.7183 | |
| 497 | N | B | -2.1549 | |
| 498 | P | B | -1.6194 | |
| 499 | E | B | -2.3247 | |
| 500 | L | B | 0.0000 | |
| 501 | T | B | -0.5453 | |
| 502 | A | B | -0.2661 | |
| 503 | M | B | 0.0000 | |
| 504 | L | B | 0.5987 | |
| 505 | T | B | 0.0640 | |
| 506 | F | B | 0.0000 | |
| 507 | K | B | -1.4615 | |
| 508 | F | B | 0.0000 | |
| 509 | Y | B | -1.1519 | |
| 510 | M | B | 0.0000 | |
| 511 | P | B | 0.0000 | |
| 512 | K | B | -3.4776 | |
| 513 | K | B | -3.0634 | |
| 514 | A | B | -2.0053 | |
| 515 | T | B | -1.2618 | |
| 516 | E | B | -1.8274 | |
| 517 | L | B | -1.1968 | |
| 518 | K | B | -1.2970 | |
| 519 | H | B | -1.4492 | |
| 520 | L | B | 0.0000 | |
| 521 | Q | B | 0.0000 | |
| 522 | C | B | 0.0000 | |
| 523 | L | B | 0.0000 | |
| 524 | E | B | -0.4281 | |
| 525 | E | B | -0.5965 | |
| 526 | E | B | 0.0000 | |
| 527 | L | B | 0.0000 | |
| 528 | K | B | -0.5063 | |
| 529 | P | B | 0.0000 | |
| 530 | L | B | 0.0000 | |
| 531 | E | B | 0.0000 | |
| 532 | E | B | 0.0000 | |
| 533 | V | B | 0.0000 | |
| 534 | L | B | 0.0000 | |
| 535 | N | B | -0.6747 | |
| 536 | L | B | 0.0000 | |
| 537 | A | B | 0.0000 | |
| 538 | Q | B | -1.9252 | |
| 539 | S | B | -1.9902 | |
| 540 | K | B | -2.6549 | |
| 541 | N | B | -2.5207 | |
| 542 | F | B | 0.0000 | |
| 543 | H | B | -2.1191 | |
| 544 | L | B | -1.6211 | |
| 545 | R | B | -2.6536 | |
| 546 | P | B | 0.0000 | |
| 547 | R | B | -2.0243 | |
| 548 | D | B | -2.2556 | |
| 549 | L | B | -1.4262 | |
| 550 | I | B | 0.0000 | |
| 551 | S | B | -1.2512 | |
| 552 | N | B | -1.1415 | |
| 553 | I | B | 0.0000 | |
| 554 | N | B | -0.4039 | |
| 555 | V | B | 0.4307 | |
| 556 | I | B | -0.0870 | |
| 557 | V | B | 0.0000 | |
| 558 | L | B | 0.2511 | |
| 559 | E | B | -0.7885 | |
| 560 | L | B | 0.0000 | |
| 561 | K | B | -1.1641 | |
| 562 | G | B | -1.2663 | |
| 563 | S | B | -1.3964 | |
| 564 | E | B | -2.0122 | |
| 565 | T | B | -0.9927 | |
| 566 | T | B | -0.4120 | |
| 567 | F | B | -0.1604 | |
| 568 | M | B | 0.4007 | |
| 569 | C | B | 0.0000 | |
| 570 | E | B | -2.3570 | |
| 571 | Y | B | -2.1668 | |
| 572 | A | B | -2.7212 | |
| 573 | D | B | -3.0709 | |
| 574 | E | B | -2.9987 | |
| 575 | T | B | -1.8509 | |
| 576 | A | B | -1.2391 | |
| 577 | T | B | -0.6620 | |
| 578 | I | B | 0.0000 | |
| 579 | V | B | -0.6299 | |
| 580 | E | B | -2.0689 | |
| 581 | F | B | 0.0000 | |
| 582 | L | B | 0.0000 | |
| 583 | N | B | -1.5408 | |
| 584 | R | B | -1.5092 | |
| 585 | W | B | 0.0000 | |
| 586 | I | B | -1.0693 | |
| 587 | T | B | -0.9931 | |
| 588 | F | B | 0.0000 | |
| 589 | S | B | 0.0000 | |
| 590 | D | B | -1.8802 | |
| 591 | S | B | -1.0555 | |
| 592 | I | B | 0.0000 | |
| 593 | I | B | -0.6110 | |
| 594 | S | B | -0.5001 | |
| 595 | T | B | -0.1203 | |
| 596 | L | B | 0.2858 | |
| 597 | T | B | 0.0070 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine