| Chain sequence(s) |
A: EVQLVESGGGLVKPGGSLRLSCAVSGFSLSNYHMSWVRQAPGKGLEWIGIISSNGNPYYADWARGRFTISKDDSKNTLYLQMNSLKTEDTAVYFCASDNSDGSLDYYGMDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGGGGSGGGGSGGGGSEVQLVESGGGLVQPGGSLRLSCAASGFTFDDYAISWFRQAPGKGLEWVSTISSGGGTLFYTYHADSVKGRFTTFRDNAKNSVYLQMNSLRDEDTAVYYCARGTYCSTDVCSPDYWGQGTLVTVSS
C: DIQMTQSPSSVSASVGDRVTITCQASQNIYSNLAWYQQKPGKAPKLLIYKASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSAYYGSGAADNAFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC input PDB |
| Selected Chain(s) | A,C |
| Distance of aggregation | 5 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with all chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:00)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:08:04)
[INFO] Main: Simulation completed successfully. (00:08:11)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | E | A | -1.7125 | |
| 2 | V | A | -0.0212 | |
| 3 | Q | A | -1.0906 | |
| 4 | L | A | 0.0000 | |
| 5 | V | A | 1.5401 | |
| 6 | E | A | 0.0000 | |
| 7 | S | A | -0.2690 | |
| 8 | G | A | -0.4588 | |
| 9 | G | A | -0.1748 | |
| 10 | G | A | -0.0553 | |
| 11 | L | A | 0.4633 | |
| 12 | V | A | -0.0427 | |
| 13 | K | A | -1.6840 | |
| 14 | P | A | -0.4882 | |
| 15 | G | A | -0.5182 | |
| 16 | G | A | -0.1919 | |
| 17 | S | A | -0.2518 | |
| 18 | L | A | -0.1246 | |
| 19 | R | A | -1.8415 | |
| 20 | L | A | 0.0000 | |
| 21 | S | A | -0.0344 | |
| 22 | C | A | 0.0000 | |
| 23 | A | A | 0.0252 | |
| 24 | V | A | 0.0000 | |
| 25 | S | A | -0.2824 | |
| 26 | G | A | -0.3725 | |
| 27 | F | A | 0.1378 | |
| 28 | S | A | -0.0696 | |
| 29 | L | A | 0.0000 | |
| 30 | S | A | -0.3732 | |
| 31 | N | A | -1.2177 | |
| 32 | Y | A | 0.1919 | |
| 33 | H | A | -0.0454 | |
| 34 | M | A | 0.0000 | |
| 35 | S | A | 0.0000 | |
| 36 | W | A | 0.0000 | |
| 37 | V | A | 0.0000 | |
| 38 | R | A | 0.0000 | |
| 39 | Q | A | -0.1503 | |
| 40 | A | A | -0.0631 | |
| 41 | P | A | -0.3375 | |
| 42 | G | A | -0.8146 | |
| 43 | K | A | -1.8068 | |
| 44 | G | A | -0.4425 | |
| 45 | L | A | 0.0000 | |
| 46 | E | A | -0.7744 | |
| 47 | W | A | 0.0000 | |
| 48 | I | A | 0.0000 | |
| 49 | G | A | 0.0000 | |
| 50 | I | A | 0.0000 | |
| 51 | I | A | 0.0000 | |
| 52 | S | A | 0.0000 | |
| 53 | S | A | -0.2475 | |
| 54 | N | A | -1.3151 | |
| 55 | G | A | -0.5530 | |
| 56 | N | A | -0.8498 | |
| 57 | P | A | -0.1911 | |
| 58 | Y | A | 0.2530 | |
| 59 | Y | A | 0.2542 | |
| 60 | A | A | 0.0000 | |
| 61 | D | A | -1.7200 | |
| 62 | W | A | 0.0629 | |
| 63 | A | A | 0.0000 | |
| 64 | R | A | -1.9286 | |
| 65 | G | A | -0.8640 | |
| 66 | R | A | -0.4403 | |
| 67 | F | A | 0.0000 | |
| 68 | T | A | -0.0462 | |
| 69 | I | A | 0.0000 | |
| 70 | S | A | -0.1369 | |
| 71 | K | A | -0.3254 | |
| 72 | D | A | -0.6773 | |
| 73 | D | A | -1.2357 | |
| 74 | S | A | -0.7105 | |
| 75 | K | A | -1.7793 | |
| 76 | N | A | -0.6692 | |
| 77 | T | A | -0.0449 | |
| 78 | L | A | 0.0000 | |
| 79 | Y | A | 0.1371 | |
| 80 | L | A | 0.0000 | |
| 81 | Q | A | -0.5670 | |
| 82 | M | A | 0.0000 | |
| 83 | N | A | -0.6967 | |
| 84 | S | A | -0.3310 | |
| 85 | L | A | 0.0000 | |
| 86 | K | A | -1.2892 | |
| 87 | T | A | -0.6282 | |
| 88 | E | A | -1.8326 | |
| 89 | D | A | 0.0000 | |
| 90 | T | A | -0.0130 | |
| 91 | A | A | 0.0000 | |
| 92 | V | A | 0.4819 | |
| 93 | Y | A | 0.0000 | |
| 94 | F | A | 0.0000 | |
| 95 | C | A | 0.0000 | |
| 96 | A | A | 0.0000 | |
| 97 | S | A | 0.0000 | |
| 98 | D | A | 0.0000 | |
| 99 | N | A | -1.0576 | |
| 100 | S | A | -0.5829 | |
| 101 | D | A | -1.8500 | |
| 102 | G | A | -0.8217 | |
| 103 | S | A | -0.0169 | |
| 104 | L | A | 1.3484 | |
| 105 | D | A | -0.5879 | |
| 106 | Y | A | 0.0027 | |
| 107 | Y | A | 0.0000 | |
| 108 | G | A | 0.0000 | |
| 109 | M | A | 0.0000 | |
| 110 | D | A | -0.3547 | |
| 111 | P | A | -0.1454 | |
| 112 | W | A | 0.1015 | |
| 113 | G | A | 0.0000 | |
| 114 | Q | A | -1.2074 | |
| 115 | G | A | -0.2696 | |
| 116 | T | A | 0.0391 | |
| 117 | L | A | 0.3721 | |
| 118 | V | A | 0.0000 | |
| 119 | T | A | 0.0000 | |
| 120 | V | A | 0.0000 | |
| 121 | S | A | -0.0724 | |
| 122 | S | A | -0.2142 | |
| 123 | A | A | -0.0501 | |
| 124 | S | A | -0.2153 | |
| 125 | T | A | -0.2572 | |
| 126 | K | A | -1.0039 | |
| 127 | G | A | -0.2779 | |
| 128 | P | A | 0.0000 | |
| 129 | S | A | -0.0775 | |
| 130 | V | A | 0.0000 | |
| 131 | F | A | 0.0000 | |
| 132 | P | A | -0.0298 | |
| 133 | L | A | 0.0000 | |
| 134 | A | A | 0.0000 | |
| 135 | P | A | 0.0000 | |
| 136 | S | A | -0.0717 | |
| 137 | S | A | -0.3573 | |
| 138 | K | A | -0.8121 | |
| 139 | S | A | 0.0000 | |
| 140 | T | A | -0.0366 | |
| 141 | S | A | -0.1800 | |
| 142 | G | A | -0.5679 | |
| 143 | G | A | -0.5561 | |
| 144 | T | A | -0.1412 | |
| 145 | A | A | 0.0000 | |
| 146 | A | A | 0.0000 | |
| 147 | L | A | 0.0000 | |
| 148 | G | A | 0.0000 | |
| 149 | C | A | 0.0000 | |
| 150 | L | A | 0.0000 | |
| 151 | V | A | 0.0000 | |
| 152 | K | A | 0.0000 | |
| 153 | D | A | -0.3360 | |
| 154 | Y | A | 0.0000 | |
| 155 | F | A | 0.0000 | |
| 156 | P | A | 0.0000 | |
| 157 | E | A | -0.4753 | |
| 158 | P | A | -0.2990 | |
| 159 | V | A | 0.1416 | |
| 160 | T | A | 0.0119 | |
| 161 | V | A | 0.1819 | |
| 162 | S | A | -0.0270 | |
| 163 | W | A | 0.0000 | |
| 164 | N | A | -0.2651 | |
| 165 | S | A | -0.3292 | |
| 166 | G | A | -0.4500 | |
| 167 | A | A | 0.0307 | |
| 168 | L | A | 0.2652 | |
| 169 | T | A | -0.0613 | |
| 170 | S | A | -0.2615 | |
| 171 | G | A | -0.1684 | |
| 172 | V | A | 0.3143 | |
| 173 | H | A | -0.0564 | |
| 174 | T | A | -0.0536 | |
| 175 | F | A | 0.0000 | |
| 176 | P | A | -0.1668 | |
| 177 | A | A | 0.0323 | |
| 178 | V | A | 0.5202 | |
| 179 | L | A | 1.3360 | |
| 180 | Q | A | 0.0636 | |
| 181 | S | A | -0.2750 | |
| 182 | S | A | -0.2912 | |
| 183 | G | A | -0.2179 | |
| 184 | L | A | 0.2080 | |
| 185 | Y | A | 0.4106 | |
| 186 | S | A | 0.0000 | |
| 187 | L | A | 0.0000 | |
| 188 | S | A | 0.0000 | |
| 189 | S | A | 0.0000 | |
| 190 | V | A | 0.0000 | |
| 191 | V | A | 0.0000 | |
| 192 | T | A | -0.0135 | |
| 193 | V | A | 0.0000 | |
| 194 | P | A | -0.2684 | |
| 195 | S | A | -0.1408 | |
| 196 | S | A | -0.2275 | |
| 197 | S | A | -0.0236 | |
| 198 | L | A | 0.1297 | |
| 199 | G | A | -0.4399 | |
| 200 | T | A | -0.3131 | |
| 201 | Q | A | -0.8772 | |
| 202 | T | A | -0.1882 | |
| 203 | Y | A | 0.0000 | |
| 204 | I | A | 0.3608 | |
| 205 | C | A | 0.0000 | |
| 206 | N | A | -0.3515 | |
| 207 | V | A | 0.0000 | |
| 208 | N | A | -0.9144 | |
| 209 | H | A | 0.0000 | |
| 210 | K | A | -1.8669 | |
| 211 | P | A | -0.3750 | |
| 212 | S | A | -0.3046 | |
| 213 | N | A | -1.4950 | |
| 214 | T | A | -0.5580 | |
| 215 | K | A | -1.7448 | |
| 216 | V | A | -0.3557 | |
| 217 | D | A | -1.7814 | |
| 218 | K | A | -1.2104 | |
| 219 | K | A | -1.4677 | |
| 220 | V | A | 0.0000 | |
| 221 | E | A | -1.8452 | |
| 222 | P | A | -0.5699 | |
| 223 | K | A | -0.6050 | |
| 224 | S | A | -0.1784 | |
| 225 | C | A | 0.3658 | |
| 226 | D | A | -1.9694 | |
| 227 | K | A | -2.0504 | |
| 228 | T | A | -0.7350 | |
| 229 | H | A | -1.0065 | |
| 230 | T | A | -0.0663 | |
| 231 | C | A | 0.6812 | |
| 232 | P | A | -0.1628 | |
| 233 | P | A | -0.1439 | |
| 234 | C | A | 0.6428 | |
| 235 | P | A | -0.1101 | |
| 236 | A | A | -0.0328 | |
| 237 | P | A | -0.5439 | |
| 238 | E | A | -1.8528 | |
| 239 | A | A | -0.3509 | |
| 240 | A | A | -0.0168 | |
| 241 | G | A | -0.5388 | |
| 242 | G | A | -0.5474 | |
| 243 | P | A | 0.0000 | |
| 244 | S | A | -0.0901 | |
| 245 | V | A | 0.0000 | |
| 246 | F | A | 0.9500 | |
| 247 | L | A | 0.5977 | |
| 248 | F | A | 1.3410 | |
| 249 | P | A | 0.0223 | |
| 250 | P | A | 0.0000 | |
| 251 | K | A | -1.7075 | |
| 252 | P | A | -0.4215 | |
| 253 | K | A | -0.4741 | |
| 254 | D | A | -0.3524 | |
| 255 | T | A | 0.0000 | |
| 256 | L | A | 0.0000 | |
| 257 | M | A | 0.5060 | |
| 258 | I | A | 2.0003 | |
| 259 | S | A | -0.0790 | |
| 260 | R | A | -1.3185 | |
| 261 | T | A | -0.3038 | |
| 262 | P | A | 0.0000 | |
| 263 | E | A | -1.0622 | |
| 264 | V | A | 0.0000 | |
| 265 | T | A | -0.0134 | |
| 266 | C | A | 0.0000 | |
| 267 | V | A | 0.0000 | |
| 268 | V | A | 0.0000 | |
| 269 | V | A | -0.0710 | |
| 270 | D | A | -0.9361 | |
| 271 | V | A | 0.0000 | |
| 272 | S | A | -0.2383 | |
| 273 | H | A | -1.3296 | |
| 274 | E | A | -2.0543 | |
| 275 | D | A | -0.6425 | |
| 276 | P | A | -0.4292 | |
| 277 | E | A | -1.7852 | |
| 278 | V | A | -0.4215 | |
| 279 | K | A | -1.6148 | |
| 280 | F | A | -0.0843 | |
| 281 | N | A | 0.0000 | |
| 282 | W | A | 0.0000 | |
| 283 | Y | A | 0.1730 | |
| 284 | V | A | -0.0778 | |
| 285 | D | A | -1.9764 | |
| 286 | G | A | -0.4704 | |
| 287 | V | A | 1.5132 | |
| 288 | E | A | -0.6471 | |
| 289 | V | A | -0.0802 | |
| 290 | H | A | -1.1657 | |
| 291 | N | A | -1.4484 | |
| 292 | A | A | -0.5267 | |
| 293 | K | A | -1.7064 | |
| 294 | T | A | -0.4917 | |
| 295 | K | A | -0.7523 | |
| 296 | P | A | -0.6732 | |
| 297 | R | A | -1.9729 | |
| 298 | E | A | -2.4559 | |
| 299 | E | A | -2.2331 | |
| 300 | Q | A | -0.4911 | |
| 301 | Y | A | 1.0104 | |
| 302 | N | A | -1.0701 | |
| 303 | S | A | -0.4408 | |
| 304 | T | A | -0.0526 | |
| 305 | Y | A | 0.0000 | |
| 306 | R | A | -0.9686 | |
| 307 | V | A | 0.0000 | |
| 308 | V | A | 0.2051 | |
| 309 | S | A | 0.0000 | |
| 310 | V | A | 0.0000 | |
| 311 | L | A | 0.0000 | |
| 312 | T | A | -0.2059 | |
| 313 | V | A | 0.0000 | |
| 314 | L | A | 1.1863 | |
| 315 | H | A | -0.1040 | |
| 316 | Q | A | -1.2830 | |
| 317 | D | A | -0.5801 | |
| 318 | W | A | 0.0000 | |
| 319 | L | A | -0.0007 | |
| 320 | N | A | -1.2318 | |
| 321 | G | A | 0.0000 | |
| 322 | K | A | -0.7721 | |
| 323 | E | A | -1.6632 | |
| 324 | Y | A | 0.0000 | |
| 325 | K | A | -0.4107 | |
| 326 | C | A | 0.0000 | |
| 327 | K | A | -0.5583 | |
| 328 | V | A | 0.0000 | |
| 329 | S | A | -0.1135 | |
| 330 | N | A | 0.0000 | |
| 331 | K | A | -1.6931 | |
| 332 | A | A | -0.2390 | |
| 333 | L | A | 0.1382 | |
| 334 | P | A | -0.2125 | |
| 335 | A | A | -0.0271 | |
| 336 | P | A | -0.1310 | |
| 337 | I | A | 0.1660 | |
| 338 | E | A | -1.5532 | |
| 339 | K | A | -1.0560 | |
| 340 | T | A | -0.1957 | |
| 341 | I | A | 0.3218 | |
| 342 | S | A | -0.1643 | |
| 343 | K | A | 0.0000 | |
| 344 | A | A | -0.2748 | |
| 345 | K | A | -1.7795 | |
| 346 | G | A | -0.9966 | |
| 347 | Q | A | -1.2953 | |
| 348 | P | A | -0.3832 | |
| 349 | R | A | -1.0256 | |
| 350 | E | A | -1.9492 | |
| 351 | P | A | 0.0000 | |
| 352 | Q | A | -0.9882 | |
| 353 | V | A | 0.0000 | |
| 354 | Y | A | 0.8121 | |
| 355 | T | A | 0.2529 | |
| 356 | L | A | 0.5924 | |
| 357 | P | A | -0.0895 | |
| 358 | P | A | -0.0869 | |
| 359 | S | A | -0.4696 | |
| 360 | R | A | -2.1974 | |
| 361 | E | A | -2.2269 | |
| 362 | E | A | -0.7030 | |
| 363 | M | A | 0.0788 | |
| 364 | T | A | -0.3453 | |
| 365 | K | A | -1.9447 | |
| 366 | N | A | -1.7702 | |
| 367 | Q | A | -1.3854 | |
| 368 | V | A | 0.0000 | |
| 369 | S | A | -0.0352 | |
| 370 | L | A | 0.0000 | |
| 371 | T | A | -0.0755 | |
| 372 | C | A | 0.0000 | |
| 373 | L | A | 0.2428 | |
| 374 | V | A | 0.0000 | |
| 375 | K | A | -0.5666 | |
| 376 | G | A | -0.1691 | |
| 377 | F | A | 0.0000 | |
| 378 | Y | A | 0.1493 | |
| 379 | P | A | 0.0000 | |
| 380 | S | A | -0.2221 | |
| 381 | D | A | -0.8534 | |
| 382 | I | A | 0.0498 | |
| 383 | A | A | 0.0000 | |
| 384 | V | A | 0.0000 | |
| 385 | E | A | -0.5052 | |
| 386 | W | A | 0.0000 | |
| 387 | E | A | -0.4193 | |
| 388 | S | A | 0.0000 | |
| 389 | N | A | -1.3567 | |
| 390 | G | A | -0.9095 | |
| 391 | Q | A | -1.3280 | |
| 392 | P | A | -0.5257 | |
| 393 | E | A | 0.0000 | |
| 394 | N | A | -1.5007 | |
| 395 | N | A | -1.4471 | |
| 396 | Y | A | -0.2565 | |
| 397 | K | A | -1.6508 | |
| 398 | T | A | -0.3476 | |
| 399 | T | A | -0.0871 | |
| 400 | P | A | -0.2758 | |
| 401 | P | A | 0.0594 | |
| 402 | V | A | 1.2920 | |
| 403 | L | A | 1.6542 | |
| 404 | D | A | -0.4006 | |
| 405 | S | A | -0.6515 | |
| 406 | D | A | -1.8858 | |
| 407 | G | A | -0.6448 | |
| 408 | S | A | 0.0000 | |
| 409 | F | A | 0.5501 | |
| 410 | F | A | 0.3382 | |
| 411 | L | A | 0.0000 | |
| 412 | Y | A | 0.6252 | |
| 413 | S | A | 0.0000 | |
| 414 | K | A | -1.1514 | |
| 415 | L | A | 0.0000 | |
| 416 | T | A | -0.0157 | |
| 417 | V | A | 0.0000 | |
| 418 | D | A | -1.1141 | |
| 419 | K | A | -0.7807 | |
| 420 | S | A | -0.4132 | |
| 421 | R | A | -0.5688 | |
| 422 | W | A | 0.0000 | |
| 423 | Q | A | -1.4180 | |
| 424 | Q | A | -1.4386 | |
| 425 | G | A | -0.3027 | |
| 426 | N | A | -0.1728 | |
| 427 | V | A | 1.2978 | |
| 428 | F | A | 0.0000 | |
| 429 | S | A | 0.0000 | |
| 430 | C | A | 0.0000 | |
| 431 | S | A | 0.0000 | |
| 432 | V | A | 0.0000 | |
| 433 | M | A | 0.0000 | |
| 434 | H | A | 0.0000 | |
| 435 | E | A | -0.2357 | |
| 436 | A | A | -0.2261 | |
| 437 | L | A | -0.0461 | |
| 438 | H | A | -1.1903 | |
| 439 | N | A | -1.4827 | |
| 440 | H | A | -0.2883 | |
| 441 | Y | A | 0.4789 | |
| 442 | T | A | -0.0372 | |
| 443 | Q | A | -0.8005 | |
| 444 | K | A | -0.8887 | |
| 445 | S | A | -0.3474 | |
| 446 | L | A | 0.0000 | |
| 447 | S | A | 0.2406 | |
| 448 | L | A | 0.7388 | |
| 449 | S | A | 0.0000 | |
| 450 | P | A | -0.2125 | |
| 451 | G | A | -0.8255 | |
| 452 | K | A | -1.8723 | |
| 453 | G | A | -0.8688 | |
| 454 | G | A | -0.6378 | |
| 455 | G | A | -0.6376 | |
| 456 | G | A | -0.5918 | |
| 457 | S | A | -0.2983 | |
| 458 | G | A | -0.5534 | |
| 459 | G | A | -0.6375 | |
| 460 | G | A | -0.5505 | |
| 461 | G | A | -0.5055 | |
| 462 | S | A | -0.3835 | |
| 463 | G | A | -0.5923 | |
| 464 | G | A | -0.6383 | |
| 465 | G | A | -0.6369 | |
| 466 | G | A | -0.5915 | |
| 467 | S | A | -0.6576 | |
| 468 | E | A | -1.8143 | |
| 469 | V | A | -0.1422 | |
| 470 | Q | A | -0.6514 | |
| 471 | L | A | 0.0000 | |
| 472 | V | A | 0.8728 | |
| 473 | E | A | 0.0000 | |
| 474 | S | A | -0.2472 | |
| 475 | G | A | -0.3973 | |
| 476 | G | A | -0.2837 | |
| 477 | G | A | 0.0618 | |
| 478 | L | A | 1.5106 | |
| 479 | V | A | 0.0000 | |
| 480 | Q | A | -1.2193 | |
| 481 | P | A | -0.4170 | |
| 482 | G | A | -0.5216 | |
| 483 | G | A | -0.1751 | |
| 484 | S | A | -0.2247 | |
| 485 | L | A | -0.1378 | |
| 486 | R | A | -1.8237 | |
| 487 | L | A | 0.0000 | |
| 488 | S | A | -0.0268 | |
| 489 | C | A | 0.0000 | |
| 490 | A | A | 0.0224 | |
| 491 | A | A | 0.0000 | |
| 492 | S | A | -0.2462 | |
| 493 | G | A | -0.3399 | |
| 494 | F | A | 0.2178 | |
| 495 | T | A | -0.0230 | |
| 496 | F | A | 0.0000 | |
| 497 | D | A | -0.9021 | |
| 498 | D | A | -1.8277 | |
| 499 | Y | A | -0.0315 | |
| 500 | A | A | 0.0473 | |
| 501 | I | A | 0.0000 | |
| 502 | S | A | 0.0000 | |
| 503 | W | A | 0.0000 | |
| 504 | F | A | 0.0000 | |
| 505 | R | A | 0.0000 | |
| 506 | Q | A | -0.4571 | |
| 507 | A | A | -0.1427 | |
| 508 | P | A | -0.3382 | |
| 509 | G | A | -0.8149 | |
| 510 | K | A | -1.8694 | |
| 511 | G | A | -0.6250 | |
| 512 | L | A | 0.6365 | |
| 513 | E | A | -0.1425 | |
| 514 | W | A | 0.0000 | |
| 515 | V | A | 0.0000 | |
| 516 | S | A | 0.0000 | |
| 517 | T | A | 0.0000 | |
| 518 | I | A | 0.0000 | |
| 519 | S | A | -0.0552 | |
| 520 | S | A | -0.0857 | |
| 521 | G | A | -0.2744 | |
| 522 | G | A | -0.6327 | |
| 523 | G | A | -0.5641 | |
| 524 | T | A | 0.1250 | |
| 525 | L | A | 1.6193 | |
| 526 | F | A | 0.9858 | |
| 527 | Y | A | 1.3935 | |
| 528 | T | A | 0.4558 | |
| 529 | Y | A | 1.2851 | |
| 530 | H | A | 0.1096 | |
| 531 | A | A | 0.0000 | |
| 532 | D | A | -1.9778 | |
| 533 | S | A | -0.4142 | |
| 534 | V | A | 0.0000 | |
| 535 | K | A | -1.9656 | |
| 536 | G | A | -0.8265 | |
| 537 | R | A | -0.3668 | |
| 538 | F | A | 0.0000 | |
| 539 | T | A | -0.0529 | |
| 540 | T | A | 0.0000 | |
| 541 | F | A | 0.6365 | |
| 542 | R | A | 0.0000 | |
| 543 | D | A | -0.7670 | |
| 544 | N | A | -0.3674 | |
| 545 | A | A | -0.2781 | |
| 546 | K | A | -1.7833 | |
| 547 | N | A | -0.8474 | |
| 548 | S | A | 0.0000 | |
| 549 | V | A | 0.0000 | |
| 550 | Y | A | 0.1478 | |
| 551 | L | A | 0.0000 | |
| 552 | Q | A | -0.4094 | |
| 553 | M | A | 0.0000 | |
| 554 | N | A | -0.5328 | |
| 555 | S | A | -0.3144 | |
| 556 | L | A | 0.0000 | |
| 557 | R | A | -1.2249 | |
| 558 | D | A | -2.2801 | |
| 559 | E | A | -2.1413 | |
| 560 | D | A | 0.0000 | |
| 561 | T | A | -0.0147 | |
| 562 | A | A | 0.0000 | |
| 563 | V | A | 0.6157 | |
| 564 | Y | A | 0.0000 | |
| 565 | Y | A | 0.2037 | |
| 566 | C | A | 0.0000 | |
| 567 | A | A | 0.0000 | |
| 568 | R | A | 0.0000 | |
| 569 | G | A | 0.0000 | |
| 570 | T | A | 0.1674 | |
| 571 | Y | A | 1.3261 | |
| 572 | C | A | 0.3872 | |
| 573 | S | A | -0.0434 | |
| 574 | T | A | -0.4069 | |
| 575 | D | A | -1.6237 | |
| 576 | V | A | 0.7013 | |
| 577 | C | A | 0.3399 | |
| 578 | S | A | -0.0998 | |
| 579 | P | A | -0.3402 | |
| 580 | D | A | -1.3132 | |
| 581 | Y | A | 0.6034 | |
| 582 | W | A | 0.7959 | |
| 583 | G | A | -0.1496 | |
| 584 | Q | A | -1.2080 | |
| 585 | G | A | 0.0000 | |
| 586 | T | A | 0.2767 | |
| 587 | L | A | 1.6036 | |
| 588 | V | A | 0.0000 | |
| 589 | T | A | 0.1509 | |
| 590 | V | A | 0.0000 | |
| 591 | S | A | -0.1621 | |
| 592 | S | A | -0.2357 | |
| 1 | D | C | -1.7894 | |
| 2 | I | C | 0.0000 | |
| 3 | Q | C | -1.1983 | |
| 4 | M | C | 0.0000 | |
| 5 | T | C | -0.0962 | |
| 6 | Q | C | -0.1783 | |
| 7 | S | C | -0.2114 | |
| 8 | P | C | -0.2084 | |
| 9 | S | C | -0.2648 | |
| 10 | S | C | -0.2317 | |
| 11 | V | C | 0.2764 | |
| 12 | S | C | -0.1743 | |
| 13 | A | C | 0.0000 | |
| 14 | S | C | 0.0186 | |
| 15 | V | C | 1.2348 | |
| 16 | G | C | -0.3993 | |
| 17 | D | C | -1.3080 | |
| 18 | R | C | -2.0133 | |
| 19 | V | C | 0.0000 | |
| 20 | T | C | -0.0609 | |
| 21 | I | C | 0.0000 | |
| 22 | T | C | -0.0378 | |
| 23 | C | C | 0.0000 | |
| 24 | Q | C | -1.2237 | |
| 25 | A | C | 0.0000 | |
| 26 | S | C | -0.3644 | |
| 27 | Q | C | -1.1131 | |
| 28 | N | C | -1.4378 | |
| 29 | I | C | 0.0000 | |
| 30 | Y | C | 1.2943 | |
| 31 | S | C | 0.1878 | |
| 32 | N | C | 0.0000 | |
| 33 | L | C | 0.0000 | |
| 34 | A | C | 0.0000 | |
| 35 | W | C | 0.0000 | |
| 36 | Y | C | 0.0000 | |
| 37 | Q | C | -0.1282 | |
| 38 | Q | C | 0.0000 | |
| 39 | K | C | -0.6755 | |
| 40 | P | C | -0.3332 | |
| 41 | G | C | -0.7955 | |
| 42 | K | C | -1.7816 | |
| 43 | A | C | -0.3039 | |
| 44 | P | C | 0.0000 | |
| 45 | K | C | -1.4846 | |
| 46 | L | C | 0.0000 | |
| 47 | L | C | 0.0000 | |
| 48 | I | C | 0.0000 | |
| 49 | Y | C | 0.2294 | |
| 50 | K | C | -0.2773 | |
| 51 | A | C | 0.0000 | |
| 52 | S | C | -0.2259 | |
| 53 | T | C | 0.0362 | |
| 54 | L | C | 0.4858 | |
| 55 | E | C | -0.3365 | |
| 56 | S | C | -0.3707 | |
| 57 | G | C | -0.4698 | |
| 58 | V | C | 0.0913 | |
| 59 | P | C | -0.1234 | |
| 60 | S | C | -0.2839 | |
| 61 | R | C | -0.3135 | |
| 62 | F | C | 0.0000 | |
| 63 | S | C | -0.1998 | |
| 64 | G | C | -0.1590 | |
| 65 | S | C | -0.2780 | |
| 66 | G | C | -0.3790 | |
| 67 | S | C | -0.2830 | |
| 68 | G | C | -0.0929 | |
| 69 | T | C | -0.3437 | |
| 70 | D | C | -1.8119 | |
| 71 | F | C | 0.0000 | |
| 72 | T | C | -0.0201 | |
| 73 | L | C | 0.0000 | |
| 74 | T | C | -0.0218 | |
| 75 | I | C | 0.0000 | |
| 76 | S | C | -0.2939 | |
| 77 | S | C | -0.1871 | |
| 78 | L | C | 0.0000 | |
| 79 | Q | C | -0.5889 | |
| 80 | P | C | -0.4004 | |
| 81 | E | C | -1.2264 | |
| 82 | D | C | 0.0000 | |
| 83 | F | C | 0.0000 | |
| 84 | A | C | 0.0000 | |
| 85 | T | C | -0.1185 | |
| 86 | Y | C | 0.0000 | |
| 87 | Y | C | 0.0000 | |
| 88 | C | C | 0.0000 | |
| 89 | Q | C | 0.0000 | |
| 90 | S | C | 0.0000 | |
| 91 | A | C | 0.0000 | |
| 92 | Y | C | 0.2235 | |
| 93 | Y | C | 0.2222 | |
| 94 | G | C | -0.0688 | |
| 95 | S | C | -0.3086 | |
| 96 | G | C | -0.4990 | |
| 97 | A | C | -0.0521 | |
| 98 | A | C | -0.0156 | |
| 99 | D | C | -0.3058 | |
| 100 | N | C | 0.0000 | |
| 101 | A | C | 0.0408 | |
| 102 | F | C | 0.1892 | |
| 103 | G | C | 0.0000 | |
| 104 | G | C | -0.4663 | |
| 105 | G | C | 0.0000 | |
| 106 | T | C | 0.0000 | |
| 107 | K | C | -0.7605 | |
| 108 | V | C | 0.0000 | |
| 109 | E | C | -0.4511 | |
| 110 | I | C | 0.0000 | |
| 111 | K | C | -1.4350 | |
| 112 | R | C | -0.8908 | |
| 113 | T | C | 0.0143 | |
| 114 | V | C | 1.0920 | |
| 115 | A | C | 0.2163 | |
| 116 | A | C | 0.0062 | |
| 117 | P | C | 0.0000 | |
| 118 | S | C | -0.0911 | |
| 119 | V | C | 0.0000 | |
| 120 | F | C | 0.0000 | |
| 121 | I | C | 0.0000 | |
| 122 | F | C | 0.0000 | |
| 123 | P | C | -0.0348 | |
| 124 | P | C | 0.0000 | |
| 125 | S | C | 0.0000 | |
| 126 | D | C | -2.0308 | |
| 127 | E | C | -1.6611 | |
| 128 | Q | C | 0.0000 | |
| 129 | L | C | -0.1135 | |
| 130 | K | C | -1.7047 | |
| 131 | S | C | -0.5642 | |
| 132 | G | C | -0.3755 | |
| 133 | T | C | -0.1625 | |
| 134 | A | C | 0.0000 | |
| 135 | S | C | 0.0000 | |
| 136 | V | C | 0.0000 | |
| 137 | V | C | 0.0000 | |
| 138 | C | C | 0.0000 | |
| 139 | L | C | 0.0000 | |
| 140 | L | C | 0.0000 | |
| 141 | N | C | 0.0000 | |
| 142 | N | C | -0.5560 | |
| 143 | F | C | 0.0000 | |
| 144 | Y | C | 0.0000 | |
| 145 | P | C | -0.3320 | |
| 146 | R | C | -1.9561 | |
| 147 | E | C | -2.1110 | |
| 148 | A | C | -0.6318 | |
| 149 | K | C | -1.6638 | |
| 150 | V | C | -0.2380 | |
| 151 | Q | C | -0.5625 | |
| 152 | W | C | 0.0000 | |
| 153 | K | C | -0.0936 | |
| 154 | V | C | 0.0000 | |
| 155 | D | C | -1.0122 | |
| 156 | N | C | -1.4140 | |
| 157 | A | C | 0.0857 | |
| 158 | L | C | 1.3653 | |
| 159 | Q | C | -0.0715 | |
| 160 | S | C | -0.3512 | |
| 161 | G | C | -0.6844 | |
| 162 | N | C | -1.0950 | |
| 163 | S | C | -0.3317 | |
| 164 | Q | C | -0.7785 | |
| 165 | E | C | -1.4115 | |
| 166 | S | C | -0.2173 | |
| 167 | V | C | 0.2593 | |
| 168 | T | C | -0.2994 | |
| 169 | E | C | -1.8213 | |
| 170 | Q | C | 0.0000 | |
| 171 | D | C | -0.6403 | |
| 172 | S | C | -0.6269 | |
| 173 | K | C | -1.8102 | |
| 174 | D | C | -0.7085 | |
| 175 | S | C | -0.1608 | |
| 176 | T | C | 0.0000 | |
| 177 | Y | C | 0.0000 | |
| 178 | S | C | 0.0000 | |
| 179 | L | C | 0.0000 | |
| 180 | S | C | 0.0000 | |
| 181 | S | C | 0.0000 | |
| 182 | T | C | -0.0096 | |
| 183 | L | C | 0.0000 | |
| 184 | T | C | 0.0129 | |
| 185 | L | C | 0.1485 | |
| 186 | S | C | -0.2166 | |
| 187 | K | C | -0.7814 | |
| 188 | A | C | -0.2347 | |
| 189 | D | C | -0.8659 | |
| 190 | Y | C | 0.0000 | |
| 191 | E | C | -1.9502 | |
| 192 | K | C | -2.0597 | |
| 193 | H | C | -0.7818 | |
| 194 | K | C | -0.5401 | |
| 195 | V | C | 0.3010 | |
| 196 | Y | C | 0.0000 | |
| 197 | A | C | 0.0000 | |
| 198 | C | C | 0.0000 | |
| 199 | E | C | -0.3490 | |
| 200 | V | C | 0.0000 | |
| 201 | T | C | -0.0649 | |
| 202 | H | C | 0.0000 | |
| 203 | Q | C | -1.2319 | |
| 204 | G | C | -0.3536 | |
| 205 | L | C | 0.1700 | |
| 206 | S | C | -0.2074 | |
| 207 | S | C | -0.2894 | |
| 208 | P | C | -0.1679 | |
| 209 | V | C | 0.4251 | |
| 210 | T | C | -0.0893 | |
| 211 | K | C | -0.4375 | |
| 212 | S | C | -0.1210 | |
| 213 | F | C | 0.0000 | |
| 214 | N | C | -0.3822 | |
| 215 | R | C | -0.3661 | |
| 216 | G | C | -0.8326 | |
| 217 | E | C | -1.7730 | |
| 218 | C | C | 0.3725 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine