Project name: LFLESSM

Chain sequence(s)	H: EVQLLESGGGLVQPGGSLRLSCAASGSIFSINAMGWFRQAPGKQRELVAVITSGGSTLYAESVKGRFTISRDNSKNTVYLQMSSLRPEDTAVYYCNAHVGLKVPTIQELSLGFGSWGQGTMVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:02)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:02)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:02)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:02)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:02)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:08)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:10)

• Minimal score value: -2.6894
• Maximal score value: 2.4201
• Average score: -0.3086
• Total score value: -38.8781

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9128
2	V	H	-0.7888
3	Q	H	-1.0167
4	L	H	0.2229
5	L	H	0.9966
6	E	H	0.2456
7	S	H	-0.3323
8	G	H	-0.8002
9	G	H	-0.1345
11	G	H	0.6173
12	L	H	1.3454
13	V	H	0.0124
14	Q	H	-1.3545
15	P	H	-1.7340
16	G	H	-1.3290
17	G	H	-0.7979
18	S	H	-0.8398
19	L	H	-0.4163
20	R	H	-1.2390
21	L	H	0.0000
22	S	H	-0.2607
23	C	H	0.0000
24	A	H	-0.4226
25	A	H	0.0000
26	S	H	-0.2785
27	G	H	-0.6410
28	S	H	0.2032
29	I	H	1.0958
30	F	H	2.4201
35	S	H	1.8199
36	I	H	1.4192
37	N	H	0.0000
38	A	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.1754
45	A	H	-1.1520
46	P	H	-0.9841
47	G	H	-1.3348
48	K	H	-1.9801
49	Q	H	-2.2436
50	R	H	-1.8028
51	E	H	-1.1778
52	L	H	0.0520
53	V	H	0.0000
54	A	H	0.0000
55	V	H	0.0000
56	I	H	0.0000
57	T	H	0.0000
58	S	H	-0.3666
59	G	H	-0.5335
63	G	H	-0.6261
64	S	H	-0.2688
65	T	H	0.3296
66	L	H	0.6377
67	Y	H	-0.2055
68	A	H	-1.0269
69	E	H	-2.3141
70	S	H	-1.7360
71	V	H	0.0000
72	K	H	-2.3807
74	G	H	-1.6287
75	R	H	-1.2021
76	F	H	0.0000
77	T	H	-0.5139
78	I	H	0.0000
79	S	H	-0.5434
80	R	H	-1.3483
81	D	H	-1.9575
82	N	H	-2.5112
83	S	H	-1.9866
84	K	H	-2.6894
85	N	H	-2.0977
86	T	H	-1.2564
87	V	H	0.0000
88	Y	H	-0.4009
89	L	H	0.0000
90	Q	H	-0.7978
91	M	H	0.0000
92	S	H	-0.8231
93	S	H	-1.0006
94	L	H	0.0000
95	R	H	-2.3617
96	P	H	-1.9787
97	E	H	-2.3642
98	D	H	0.0000
99	T	H	-0.6084
100	A	H	0.0000
101	V	H	0.2120
102	Y	H	0.0000
103	Y	H	0.1171
104	C	H	0.0000
105	N	H	0.0000
106	A	H	0.0000
107	H	H	0.5999
108	V	H	1.4248
109	G	H	1.0703
110	L	H	1.8520
111	K	H	0.0997
111A	V	H	1.5269
111B	P	H	1.1321
111C	T	H	0.9302
112D	I	H	1.3585
112C	Q	H	0.5119
112B	E	H	0.1164
112A	L	H	1.4650
112	S	H	0.8799
113	L	H	1.5446
114	G	H	0.7300
115	F	H	0.0000
116	G	H	-0.0320
117	S	H	-0.1708
118	W	H	0.1457
119	G	H	-0.0936
120	Q	H	-0.8883
121	G	H	-0.1637
122	T	H	0.0233
123	M	H	0.6762
124	V	H	0.0000
125	T	H	0.0986
126	V	H	0.0000
127	S	H	-0.8696
128	S	H	-0.9149