Project name: 7626653bd0ce4ca

Chain sequence(s)	C: DIQMTQSPSSLSASVGDRVTITCRASQGIRNYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISSLQPEDVATYYCQRYNRAPYTFGQGTKVEIKGGGSGGGSGGGSGGGSEVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSAITWNSGHIDYADSVEGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAKVSYLSTASSLDYWGQGTLVTVS
Selected Chain(s)	C
Distance of aggregation	10 Å
FoldX usage	No
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with C chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       runJob:   FoldX not utilized. Treating input pdb file as it was already optimized.    (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:01)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:02)

• Minimal score value: -2.9702
• Maximal score value: 1.8943
• Average score: -0.7506
• Total score value: -182.398

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	D	C	-2.4894
3	I	C	0.0000
4	Q	C	-2.1905
5	M	C	0.0000
6	T	C	-1.0907
7	Q	C	0.0000
8	S	C	-0.7989
9	P	C	-0.5952
10	S	C	-1.0355
11	S	C	-1.2803
12	L	C	-1.0007
13	S	C	-1.2450
14	A	C	-0.9876
15	S	C	-0.7790
16	V	C	0.0189
17	G	C	-0.9490
18	D	C	-1.8378
19	R	C	-2.3879
20	V	C	0.0000
21	T	C	-0.6396
22	I	C	0.0000
23	T	C	-0.6973
24	C	C	0.0000
25	R	C	-2.0389
26	A	C	-1.7386
27	S	C	-1.8409
28	Q	C	-2.2063
29	G	C	-2.0959
30	I	C	0.0000
31	R	C	-2.8917
32	N	C	-2.1975
33	Y	C	-1.0303
34	L	C	0.0000
35	A	C	0.0000
36	W	C	0.0000
37	Y	C	0.0000
38	Q	C	0.0000
39	Q	C	-0.8160
40	K	C	0.0000
41	P	C	-0.7496
42	G	C	-1.0689
43	K	C	-1.4243
44	A	C	0.0000
45	P	C	0.0000
46	K	C	-0.8616
47	L	C	0.0000
48	L	C	0.0000
49	I	C	0.0000
50	Y	C	0.3067
51	A	C	-0.2402
52	A	C	0.0000
53	S	C	-0.4473
54	T	C	0.0644
55	L	C	0.2588
56	Q	C	-0.1927
57	S	C	-0.3376
58	G	C	-0.4951
59	V	C	-0.2430
60	P	C	-0.3303
61	S	C	-0.4081
62	R	C	-0.8025
63	F	C	0.0000
64	S	C	-0.3277
65	G	C	-0.3012
66	S	C	-0.8502
67	G	C	-1.5718
68	S	C	-1.9848
69	G	C	-2.1750
70	T	C	-2.1301
71	D	C	-2.3123
72	F	C	0.0000
73	T	C	-0.7204
74	L	C	0.0000
75	T	C	-0.6188
76	I	C	0.0000
77	S	C	-1.3275
78	S	C	-1.1815
79	L	C	0.0000
80	Q	C	-0.5890
81	P	C	-1.1472
82	E	C	-1.1498
83	D	C	0.0000
84	V	C	-1.4042
85	A	C	0.0000
86	T	C	-1.2152
87	Y	C	0.0000
88	Y	C	0.0000
89	C	C	0.0000
90	Q	C	0.0000
91	R	C	0.0000
92	Y	C	0.0000
93	N	C	-1.8678
94	R	C	-2.2337
95	A	C	-1.3945
96	P	C	-1.4455
97	Y	C	-0.9095
98	T	C	-1.1450
99	F	C	0.0000
100	G	C	0.0000
101	Q	C	-1.9820
102	G	C	0.0000
103	T	C	0.0000
104	K	C	-2.4151
105	V	C	0.0000
106	E	C	-2.6129
107	I	C	-1.5549
108	K	C	-2.2177
109	G	C	-1.9104
110	G	C	-1.4783
111	G	C	-1.5595
112	S	C	-1.0964
113	G	C	-1.1350
114	G	C	-1.2288
115	G	C	-1.4212
116	S	C	-1.5309
117	G	C	-1.6091
118	G	C	-1.1743
119	G	C	-1.2117
120	S	C	-1.3306
121	G	C	-1.2492
122	G	C	-1.6351
123	G	C	-1.9381
124	S	C	-1.8213
125	E	C	-2.3894
126	V	C	-1.4654
127	Q	C	-1.5133
128	L	C	0.0000
129	V	C	0.4829
130	E	C	0.1007
131	S	C	-0.4406
132	G	C	-0.8653
133	G	C	-0.0164
134	G	C	0.7422
135	L	C	1.3132
136	V	C	0.0000
137	Q	C	-1.9460
138	P	C	-2.0069
139	G	C	-2.3231
140	R	C	-2.9702
141	S	C	-2.0779
142	L	C	-1.3388
143	R	C	-2.1457
144	L	C	0.0000
145	S	C	-0.5346
146	C	C	0.0000
147	A	C	-0.2971
148	A	C	0.0000
149	S	C	-0.7850
150	G	C	-1.2019
151	F	C	-0.8134
152	T	C	-0.8423
153	F	C	0.0000
154	D	C	-2.1631
155	D	C	-1.5897
156	Y	C	-0.3736
157	A	C	0.0000
158	M	C	0.0000
159	H	C	0.0000
160	W	C	0.0000
161	V	C	0.0000
162	R	C	0.0000
163	Q	C	-0.6905
164	A	C	-1.0691
165	P	C	-0.7798
166	G	C	-1.4596
167	K	C	-2.3997
168	G	C	-1.6857
169	L	C	0.0000
170	E	C	-1.2449
171	W	C	0.0000
172	V	C	0.0000
173	S	C	0.0000
174	A	C	0.0000
175	I	C	0.0000
176	T	C	-0.4902
177	W	C	-0.8115
178	N	C	-1.7637
179	S	C	-1.0610
180	G	C	-0.9922
181	H	C	-0.9704
182	I	C	0.2252
183	D	C	-0.8943
184	Y	C	-1.0287
185	A	C	0.0000
186	D	C	-2.5989
187	S	C	-1.7222
188	V	C	0.0000
189	E	C	-2.8133
190	G	C	-1.7797
191	R	C	-1.5231
192	F	C	0.0000
193	T	C	-0.8198
194	I	C	0.0000
195	S	C	-0.3570
196	R	C	-1.1563
197	D	C	-1.6884
198	N	C	-2.1797
199	A	C	-1.5446
200	K	C	-2.2484
201	N	C	-1.8407
202	S	C	0.0000
203	L	C	0.0000
204	Y	C	-0.6110
205	L	C	0.0000
206	Q	C	-1.3177
207	M	C	0.0000
208	N	C	-1.9741
209	S	C	-1.8846
210	L	C	0.0000
211	R	C	-2.4617
212	A	C	-1.6799
213	E	C	-2.1803
214	D	C	0.0000
215	T	C	-0.4132
216	A	C	0.0000
217	V	C	0.6680
218	Y	C	0.0000
219	Y	C	0.0000
220	C	C	0.0000
221	A	C	0.0000
222	K	C	0.0000
223	V	C	0.0000
224	S	C	0.0000
225	Y	C	1.7683
226	L	C	1.8943
227	S	C	0.9012
228	T	C	0.5346
229	A	C	0.0515
230	S	C	0.0000
231	S	C	0.0000
232	L	C	0.0000
233	D	C	0.0000
234	Y	C	-0.0873
235	W	C	-0.2121
236	G	C	0.0000
237	Q	C	-1.3195
238	G	C	-0.2558
239	T	C	0.3514
240	L	C	1.4575
241	V	C	0.0000
242	T	C	0.2090
243	V	C	0.0000
244	S	C	-1.0596