Project name: 7808a3115c4d2ef

Chain sequence(s)	D: EVQLVESGGGLAKPAWSPRLSCAASGSRFSAYAMGWVRQAPGKGLEWVGTITNGGSTNYADSVKGRFNTSRDNAKNTLHLQMNSLKTEDTALYYCNQGGYARGYWGQGTLVTVSS
Selected Chain(s)	D
Distance of aggregation	10 Å
FoldX usage	No
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:09)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:09)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with D chain(s) selected             (00:00:09)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:09)
[INFO]       runJob:   FoldX not utilized. Treating input pdb file as it was already optimized.    (00:00:09)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:09)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:10)

• Minimal score value: -2.9323
• Maximal score value: 1.3667
• Average score: -0.6453
• Total score value: -74.2046

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	E	D	-2.1709
3	V	D	-1.3172
4	Q	D	-1.1281
5	L	D	0.0000
6	V	D	1.1280
7	E	D	0.3871
8	S	D	-0.2899
9	G	D	-1.1203
10	G	D	-0.2067
11	G	D	0.3138
12	L	D	1.2500
13	A	D	0.0000
14	K	D	-1.2193
15	P	D	-1.1167
16	A	D	-0.3933
17	W	D	0.3580
18	S	D	-0.6858
19	P	D	-1.0189
20	R	D	-2.5226
21	L	D	0.0000
22	S	D	-0.6076
23	C	D	0.0000
24	A	D	-0.1794
25	A	D	-0.7874
26	S	D	-1.3937
27	G	D	-1.8307
28	S	D	-1.6218
29	R	D	-2.0007
30	F	D	0.0000
31	S	D	-1.1317
32	A	D	-0.4878
33	Y	D	0.1320
34	A	D	-0.1485
35	M	D	0.0000
36	G	D	0.0000
37	W	D	0.0000
38	V	D	0.0000
39	R	D	0.0000
40	Q	D	-0.3107
41	A	D	-0.9201
42	P	D	-1.0885
43	G	D	-1.4210
44	K	D	-2.0905
45	G	D	-0.9767
46	L	D	0.5342
47	E	D	-0.1669
48	W	D	0.6626
49	V	D	0.0000
50	G	D	0.0000
51	T	D	-0.5979
52	I	D	0.0000
53	T	D	-0.9726
54	N	D	-1.6261
55	G	D	-1.4546
56	G	D	-1.1011
57	S	D	-1.0500
58	T	D	-1.2052
59	N	D	-1.7751
60	Y	D	-1.5192
61	A	D	-1.5237
62	D	D	-2.5725
63	S	D	-1.7520
64	V	D	0.0000
65	K	D	-2.9323
66	G	D	-1.9560
67	R	D	-1.6119
68	F	D	0.0000
69	N	D	-2.2576
70	T	D	0.0000
71	S	D	-0.9040
72	R	D	-1.3108
73	D	D	-1.7788
74	N	D	-2.1448
75	A	D	-1.4553
76	K	D	-2.3595
77	N	D	-2.2169
78	T	D	-1.1316
79	L	D	0.0000
80	H	D	-1.0829
81	L	D	0.0000
82	Q	D	-1.8504
83	M	D	0.0000
84	N	D	-1.3476
85	S	D	-0.7260
86	L	D	0.0000
87	K	D	-2.0606
88	T	D	-1.8187
89	E	D	-2.2860
90	D	D	0.0000
91	T	D	-0.4633
92	A	D	0.0000
93	L	D	0.8419
94	Y	D	0.0000
95	Y	D	0.5235
96	C	D	0.0000
97	N	D	0.0000
98	Q	D	0.0000
99	G	D	0.0899
100	G	D	-0.0918
101	Y	D	0.8925
102	A	D	-0.2144
103	R	D	-1.3292
104	G	D	0.0593
105	Y	D	1.0349
106	W	D	0.7262
107	G	D	0.0000
108	Q	D	-0.7250
109	G	D	0.0682
110	T	D	0.4511
111	L	D	1.3667
112	V	D	0.0000
113	T	D	0.1840
114	V	D	0.0000
115	S	D	-0.8753
116	S	D	-0.7744