Project name: 7925002f5267d01

Chain sequence(s)	H: DVQLVESGGGLVQPGGSLRLSCAASGRTFSEYAMGWFRQAPGKEREFVATISWSGGATYYTDSVKGRFTISRDNAKNTVYLQMNSLRPEDTAVYYCAAAGLGTVVSEWDYDYDYWGQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:07)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:09)

• Minimal score value: -3.2137
• Maximal score value: 1.9283
• Average score: -0.487
• Total score value: -60.8812

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	H	-2.5757
2	V	H	0.0000
3	Q	H	-1.5417
4	L	H	0.0000
5	V	H	1.1023
6	E	H	0.4880
7	S	H	-0.1083
8	G	H	-0.6034
9	G	H	0.2155
11	G	H	0.8378
12	L	H	1.4641
13	V	H	0.0137
14	Q	H	-1.3062
15	P	H	-1.5108
16	G	H	-1.3303
17	G	H	-0.8569
18	S	H	-0.9688
19	L	H	-0.4749
20	R	H	-1.2293
21	L	H	0.0000
22	S	H	-0.1481
23	C	H	0.0000
24	A	H	-0.2346
25	A	H	0.0000
26	S	H	-1.4477
27	G	H	-1.9342
28	R	H	-2.0514
29	T	H	-1.0682
30	F	H	0.0000
35	S	H	-1.0390
36	E	H	-0.6809
37	Y	H	0.0000
38	A	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.4103
45	A	H	-1.4052
46	P	H	-1.2781
47	G	H	-1.8128
48	K	H	-2.9722
49	E	H	-3.2137
50	R	H	-2.3873
51	E	H	-1.5265
52	F	H	-0.5643
53	V	H	0.0000
54	A	H	0.0000
55	T	H	0.0000
56	I	H	0.0000
57	S	H	0.0000
58	W	H	0.3011
59	S	H	-0.2818
62	G	H	-0.5010
63	G	H	-0.5267
64	A	H	0.2788
65	T	H	0.4858
66	Y	H	0.2322
67	Y	H	-0.5856
68	T	H	-1.2435
69	D	H	-2.3092
70	S	H	-1.6527
71	V	H	0.0000
72	K	H	-2.0325
74	G	H	-1.5081
75	R	H	-1.3468
76	F	H	0.0000
77	T	H	-0.5428
78	I	H	0.0000
79	S	H	-0.3117
80	R	H	-0.8851
81	D	H	-1.4259
82	N	H	-1.6017
83	A	H	-1.3428
84	K	H	-2.3358
85	N	H	-2.0241
86	T	H	0.0000
87	V	H	0.0000
88	Y	H	-0.2300
89	L	H	0.0000
90	Q	H	-0.7834
91	M	H	0.0000
92	N	H	-1.1743
93	S	H	-1.1155
94	L	H	0.0000
95	R	H	-2.1951
96	P	H	-1.8885
97	E	H	-2.3041
98	D	H	0.0000
99	T	H	-0.4361
100	A	H	0.0000
101	V	H	0.7314
102	Y	H	0.0000
103	Y	H	0.2435
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	A	H	0.0000
108	G	H	0.1136
109	L	H	1.2083
110	G	H	0.4804
111	T	H	0.8853
111A	V	H	1.9283
111B	V	H	1.2171
112C	S	H	0.0000
112B	E	H	-0.2964
112A	W	H	0.6273
112	D	H	-0.3782
113	Y	H	0.5288
114	D	H	-0.3111
115	Y	H	0.0000
116	D	H	-1.7749
117	Y	H	-1.0009
118	W	H	-0.3094
119	G	H	-0.1038
120	Q	H	-0.7232
121	G	H	0.1087
122	T	H	0.5998
123	L	H	1.5965
124	V	H	0.0000
125	T	H	0.3407
126	V	H	0.0000
127	S	H	-0.8660
128	S	H	-0.8807