Project name: 7b81f619b34fdf1

Chain sequence(s)	A: EQAALIAEAERIAARVRANMAEAEAVIREGDAASQAHLPAFRAQAAELDALTAELLAALRAEDWEAAAATLRRLLAAGEEYIAIMEKAKVPQELIDRARQIRAEGERLLEKLAAAVAAHS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:03)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:04)

• Minimal score value: -3.5317
• Maximal score value: 0.0
• Average score: -1.5015
• Total score value: -180.1746

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.2086
2	Q	A	-1.9110
3	A	A	-1.1476
4	A	A	-0.9768
5	L	A	-1.5781
6	I	A	-1.6037
7	A	A	-1.5509
8	E	A	-2.4665
9	A	A	0.0000
10	E	A	-2.8544
11	R	A	-3.1123
12	I	A	-1.8826
13	A	A	-1.6393
14	A	A	-1.4823
15	R	A	-1.3581
16	V	A	-1.0670
17	R	A	-0.8614
18	A	A	-0.7171
19	N	A	0.0000
20	M	A	0.0000
21	A	A	-0.7985
22	E	A	-1.5675
23	A	A	0.0000
24	E	A	-1.6835
25	A	A	-1.3744
26	V	A	-1.5335
27	I	A	0.0000
28	R	A	-3.1991
29	E	A	-3.2099
30	G	A	-2.9324
31	D	A	-2.9712
32	A	A	-1.6867
33	A	A	-1.3419
34	S	A	0.0000
35	Q	A	-2.6265
36	A	A	-1.1988
37	H	A	-1.4475
38	L	A	-1.1413
39	P	A	-0.9589
40	A	A	-0.6307
41	F	A	0.0000
42	R	A	-2.0999
43	A	A	-1.3591
44	Q	A	-1.5947
45	A	A	0.0000
46	A	A	-1.5360
47	E	A	-1.9579
48	L	A	0.0000
49	D	A	-1.9748
50	A	A	-1.4606
51	L	A	0.0000
52	T	A	-1.4798
53	A	A	-1.2189
54	E	A	-1.8423
55	L	A	0.0000
56	L	A	-1.1364
57	A	A	-1.4124
58	A	A	-1.9947
59	L	A	0.0000
60	R	A	-2.4683
61	A	A	-2.0268
62	E	A	-3.2431
63	D	A	-2.8829
64	W	A	0.0000
65	E	A	-2.3759
66	A	A	-1.8309
67	A	A	0.0000
68	A	A	-1.7841
69	A	A	-1.4746
70	T	A	-1.7867
71	L	A	0.0000
72	R	A	-2.8124
73	R	A	-2.6344
74	L	A	-2.4249
75	L	A	0.0000
76	A	A	-2.0525
77	A	A	0.0000
78	G	A	-2.1625
79	E	A	-2.6968
80	E	A	-2.5317
81	Y	A	0.0000
82	I	A	-1.8770
83	A	A	-1.8413
84	I	A	-1.6083
85	M	A	0.0000
86	E	A	-2.7560
87	K	A	-2.7065
88	A	A	0.0000
89	K	A	-3.1090
90	V	A	0.0000
91	P	A	-2.0009
92	Q	A	-3.1288
93	E	A	-3.2384
94	L	A	0.0000
95	I	A	0.0000
96	D	A	-3.4931
97	R	A	-2.7053
98	A	A	0.0000
99	R	A	-2.7574
100	Q	A	-2.4664
101	I	A	0.0000
102	R	A	-2.1304
103	A	A	-1.8822
104	E	A	-2.1714
105	G	A	0.0000
106	E	A	-3.3253
107	R	A	-3.5317
108	L	A	0.0000
109	L	A	-2.6208
110	E	A	-3.3857
111	K	A	-3.0259
112	L	A	0.0000
113	A	A	-1.3340
114	A	A	-0.8808
115	A	A	-1.5006
116	V	A	-1.1629
117	A	A	-0.4533
118	A	A	-0.3128
119	H	A	-1.2294
120	S	A	-0.5630