Project name: 7de224bab705d12

Chain sequence(s)	A: EVQLVESGGGVVQPGGSLRLSCAASGVTLDYYAIGWFRQAPGKGLEGVSCISSDGSTFYEDSDEGRFTISRDNAKNTVYLQMNNLKPEDTAVYYCAAVRLKCVTVTYSSGRYYVYDYWGQGTLVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:04)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:04)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:04)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:04)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:05)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:37)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:38)

• Minimal score value: -2.559
• Maximal score value: 1.8013
• Average score: -0.5114
• Total score value: -65.4647

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.1119
2	V	A	-1.4723
3	Q	A	-1.3008
4	L	A	0.0000
5	V	A	0.8966
6	E	A	0.4081
7	S	A	-0.2930
8	G	A	-0.8411
9	G	A	0.1612
10	G	A	0.7684
11	V	A	1.6734
12	V	A	0.1003
13	Q	A	-1.3983
14	P	A	-1.7574
15	G	A	-1.8281
16	G	A	-1.2521
17	S	A	-1.5524
18	L	A	-1.0374
19	R	A	-2.1465
20	L	A	0.0000
21	S	A	-0.4453
22	C	A	0.0000
23	A	A	-0.2082
24	A	A	0.0000
25	S	A	-0.7719
26	G	A	-1.1752
27	V	A	-0.2948
28	T	A	-0.3757
29	L	A	0.0000
30	D	A	-1.0658
31	Y	A	0.3346
32	Y	A	0.0000
33	A	A	0.0000
34	I	A	0.0000
35	G	A	0.0000
36	W	A	0.0000
37	F	A	0.0000
38	R	A	0.0000
39	Q	A	-0.8620
40	A	A	-1.1712
41	P	A	-1.1144
42	G	A	-1.5095
43	K	A	-2.3637
44	G	A	-1.4934
45	L	A	-0.3921
46	E	A	-1.2527
47	G	A	0.0000
48	V	A	0.0000
49	S	A	0.0000
50	C	A	0.0000
51	I	A	0.0000
52	S	A	0.0000
53	S	A	-1.2614
54	D	A	-1.9980
55	G	A	-1.4182
56	S	A	-0.6549
57	T	A	0.3603
58	F	A	1.3686
59	Y	A	-0.1304
60	E	A	-1.3427
61	D	A	-2.4195
62	S	A	-1.7402
63	D	A	0.0000
64	E	A	-2.5590
65	G	A	-1.9856
66	R	A	-1.7183
67	F	A	0.0000
68	T	A	-0.6851
69	I	A	0.0000
70	S	A	-0.5615
71	R	A	-1.3151
72	D	A	-1.9968
73	N	A	-2.0330
74	A	A	-1.5634
75	K	A	-2.2948
76	N	A	-1.7521
77	T	A	0.0000
78	V	A	0.0000
79	Y	A	-0.7167
80	L	A	0.0000
81	Q	A	-1.2706
82	M	A	0.0000
83	N	A	-1.9773
84	N	A	-2.3344
85	L	A	0.0000
86	K	A	-2.4643
87	P	A	-1.8539
88	E	A	-2.2787
89	D	A	0.0000
90	T	A	-0.3724
91	A	A	0.0000
92	V	A	0.9471
93	Y	A	0.0000
94	Y	A	0.3941
95	C	A	0.0000
96	A	A	0.0000
97	A	A	0.0000
98	V	A	0.0000
99	R	A	-1.3430
100	L	A	-0.1235
101	K	A	-1.4731
102	C	A	-0.0547
103	V	A	0.5311
104	T	A	0.6456
105	V	A	1.0124
106	T	A	0.3103
107	Y	A	0.9169
108	S	A	-0.0169
109	S	A	-0.1515
110	G	A	-0.4003
111	R	A	-0.7563
112	Y	A	1.1556
113	Y	A	1.0265
114	V	A	1.0908
115	Y	A	0.0000
116	D	A	-1.4507
117	Y	A	-0.6990
118	W	A	0.0927
119	G	A	-0.0195
120	Q	A	-0.8168
121	G	A	0.0000
122	T	A	0.6609
123	L	A	1.8013
124	V	A	0.0000
125	T	A	0.4772
126	V	A	0.0000
127	S	A	-0.6407
128	S	A	-0.4672