| Chain sequence(s) |
A: VQTPHKVEVNEKIEESIEYVQNLLMTSGDGRISVSPYDTAVIALIKDLKGRDAPQFPSCLEWIAHHQLADGSWGDEFFCIYDRILNTLACVVALKSWNLQSDIIEKGVTYIKENVHKLKGANVEHRTAGFELVVPTFMQMATDLGIQGLPYDHPLIKEIADTKQQRLKEIPKDLVYQMPTNLLYSLEGLGDLEWERLLKLQSGNGSFLTSPSSTAAVLMHTKDEKCLKYIENALKNCDGGAPHTYPVDIFSRLWAIDRLQRLGISRFFQHEIKYFLDHIESVWEETGVFSGRYTKFSDIDDTSMGVRLLKMHGYDVDPNVLKHFKQQDGKFACYIGQSVESASPMYNLYRAAQLRFPGEEVLEEATKFAFNFLQEMLVKDRLQERWVISDHLFDEIKLGLKMPWYATLPRVEAAYYLDHYAGSGDVWIGKSFYRMPEISNDTYKELAILDFNRCQTQHQLEWIQMQEWYDRCSLSEFGISKRELLRSYFLAAATIFEPERTQERLLWAKTRILSKMITSFVNISGTTLSLDYNFNGLDEIISANEDQGLAGTLLATFHQLLDGFDIYTLHQLKHVWSQWFMKVQQGEGSGGEDAVLLANTLNICAGLNEDVLSNNEYTALSTLTNKICNRLAQIQDNKILQVVDGSIKDKELEQDMQALVKLVLQENGGAVDRNIRHTFLSVSKTFYYDAYHDDETTDLHIFKVLFRPVV
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 5 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | MA219A,LN99A,NA98A,LA189A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 7.9336 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:03)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:03)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:03)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:03)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:04)
[INFO] FoldX: Building mutant model (00:07:14)
[INFO] FoldX: Starting FoldX energy minimalization (00:08:00)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:14:37)
[INFO] Main: Simulation completed successfully. (00:14:47)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | V | A | 1.6126 | |
| 2 | Q | A | -0.5627 | |
| 3 | T | A | -0.2279 | |
| 4 | P | A | -0.3260 | |
| 5 | H | A | -1.3458 | |
| 6 | K | A | -1.7071 | |
| 7 | V | A | 0.5540 | |
| 8 | E | A | -0.2156 | |
| 9 | V | A | 0.0988 | |
| 10 | N | A | -0.6995 | |
| 11 | E | A | -2.0979 | |
| 12 | K | A | -1.6401 | |
| 13 | I | A | 0.0000 | |
| 14 | E | A | -2.1422 | |
| 15 | E | A | -2.2650 | |
| 16 | S | A | -0.3084 | |
| 17 | I | A | -0.0887 | |
| 18 | E | A | -1.6434 | |
| 19 | Y | A | 0.4136 | |
| 20 | V | A | 0.0000 | |
| 21 | Q | A | -0.6938 | |
| 22 | N | A | -1.3101 | |
| 23 | L | A | -0.0699 | |
| 24 | L | A | 0.0000 | |
| 25 | M | A | 0.4546 | |
| 26 | T | A | 0.0129 | |
| 27 | S | A | 0.0000 | |
| 28 | G | A | -0.5213 | |
| 29 | D | A | -1.0018 | |
| 30 | G | A | 0.0000 | |
| 31 | R | A | -0.5373 | |
| 32 | I | A | 0.0717 | |
| 33 | S | A | 0.0164 | |
| 34 | V | A | 0.3391 | |
| 35 | S | A | 0.0000 | |
| 36 | P | A | 0.0000 | |
| 37 | Y | A | 0.0000 | |
| 38 | D | A | 0.0000 | |
| 39 | T | A | 0.0000 | |
| 40 | A | A | 0.0000 | |
| 41 | V | A | 0.0000 | |
| 42 | I | A | 0.0000 | |
| 43 | A | A | 0.0000 | |
| 44 | L | A | 0.3159 | |
| 45 | I | A | 0.0000 | |
| 46 | K | A | -1.7038 | |
| 47 | D | A | 0.0000 | |
| 48 | L | A | 0.3537 | |
| 49 | K | A | -1.6644 | |
| 50 | G | A | -1.1137 | |
| 51 | R | A | -2.2505 | |
| 52 | D | A | -2.1167 | |
| 53 | A | A | -0.3183 | |
| 54 | P | A | -0.2981 | |
| 55 | Q | A | -0.2768 | |
| 56 | F | A | 0.0000 | |
| 57 | P | A | -0.1984 | |
| 58 | S | A | -0.3202 | |
| 59 | C | A | 0.0000 | |
| 60 | L | A | -0.1743 | |
| 61 | E | A | -1.7669 | |
| 62 | W | A | -0.1883 | |
| 63 | I | A | 0.0000 | |
| 64 | A | A | -0.1674 | |
| 65 | H | A | -1.1180 | |
| 66 | H | A | -0.9198 | |
| 67 | Q | A | -0.2265 | |
| 68 | L | A | 0.3336 | |
| 69 | A | A | -0.1478 | |
| 70 | D | A | -1.4805 | |
| 71 | G | A | 0.0000 | |
| 72 | S | A | 0.0000 | |
| 73 | W | A | 0.0000 | |
| 74 | G | A | -0.1433 | |
| 75 | D | A | -0.5450 | |
| 76 | E | A | -1.7120 | |
| 77 | F | A | 0.7848 | |
| 78 | F | A | 1.9391 | |
| 79 | C | A | 0.0000 | |
| 80 | I | A | 0.0000 | |
| 81 | Y | A | 0.0000 | |
| 82 | D | A | 0.0000 | |
| 83 | R | A | 0.0000 | |
| 84 | I | A | 0.0000 | |
| 85 | L | A | 0.0000 | |
| 86 | N | A | 0.0000 | |
| 87 | T | A | 0.0000 | |
| 88 | L | A | 0.0000 | |
| 89 | A | A | 0.0000 | |
| 90 | C | A | 0.0000 | |
| 91 | V | A | 0.0000 | |
| 92 | V | A | 0.0000 | |
| 93 | A | A | 0.0000 | |
| 94 | L | A | 0.0000 | |
| 95 | K | A | -0.4973 | |
| 96 | S | A | -0.1306 | |
| 97 | W | A | 0.1596 | |
| 98 | A | A | -0.1377 | mutated: NA98A |
| 99 | N | A | -1.0234 | mutated: LN99A |
| 100 | Q | A | -1.0260 | |
| 101 | S | A | -0.6887 | |
| 102 | D | A | -1.7851 | |
| 103 | I | A | -0.0856 | |
| 104 | I | A | 0.0000 | |
| 105 | E | A | -2.0954 | |
| 106 | K | A | -1.8467 | |
| 107 | G | A | 0.0000 | |
| 108 | V | A | 0.0000 | |
| 109 | T | A | -0.0709 | |
| 110 | Y | A | 0.0000 | |
| 111 | I | A | 0.0000 | |
| 112 | K | A | -1.5847 | |
| 113 | E | A | -2.0464 | |
| 114 | N | A | 0.0000 | |
| 115 | V | A | 0.0000 | |
| 116 | H | A | -1.2668 | |
| 117 | K | A | -1.7036 | |
| 118 | L | A | 0.0000 | |
| 119 | K | A | -1.7839 | |
| 120 | G | A | -0.7705 | |
| 121 | A | A | -0.2279 | |
| 122 | N | A | -0.5112 | |
| 123 | V | A | 1.5316 | |
| 124 | E | A | -0.2148 | |
| 125 | H | A | -0.4668 | |
| 126 | R | A | -0.8597 | |
| 127 | T | A | 0.0000 | |
| 128 | A | A | -0.0199 | |
| 129 | G | A | -0.1945 | |
| 130 | F | A | 0.0000 | |
| 131 | E | A | -0.2804 | |
| 132 | L | A | 0.1306 | |
| 133 | V | A | 0.0000 | |
| 134 | V | A | 0.0000 | |
| 135 | P | A | -0.0331 | |
| 136 | T | A | -0.0196 | |
| 137 | F | A | 0.0000 | |
| 138 | M | A | 0.0000 | |
| 139 | Q | A | -1.1485 | |
| 140 | M | A | -0.1256 | |
| 141 | A | A | 0.0000 | |
| 142 | T | A | -0.4194 | |
| 143 | D | A | -1.7031 | |
| 144 | L | A | -0.0107 | |
| 145 | G | A | -0.2824 | |
| 146 | I | A | 0.0000 | |
| 147 | Q | A | -1.2692 | |
| 148 | G | A | -0.6071 | |
| 149 | L | A | 0.0000 | |
| 150 | P | A | 0.0000 | |
| 151 | Y | A | 0.0183 | |
| 152 | D | A | -1.7434 | |
| 153 | H | A | -0.4738 | |
| 154 | P | A | -0.2735 | |
| 155 | L | A | 0.0000 | |
| 156 | I | A | 0.0000 | |
| 157 | K | A | -2.0261 | |
| 158 | E | A | -2.0898 | |
| 159 | I | A | -0.1279 | |
| 160 | A | A | -0.4543 | |
| 161 | D | A | -1.9032 | |
| 162 | T | A | -0.3548 | |
| 163 | K | A | -0.3932 | |
| 164 | Q | A | -1.4642 | |
| 165 | Q | A | -1.4749 | |
| 166 | R | A | -1.6250 | |
| 167 | L | A | -0.3125 | |
| 168 | K | A | -1.9738 | |
| 169 | E | A | -2.0107 | |
| 170 | I | A | 0.1034 | |
| 171 | P | A | -0.4782 | |
| 172 | K | A | -2.0230 | |
| 173 | D | A | -1.7533 | |
| 174 | L | A | 0.1329 | |
| 175 | V | A | 0.0000 | |
| 176 | Y | A | 0.0000 | |
| 177 | Q | A | -1.1444 | |
| 178 | M | A | 0.0690 | |
| 179 | P | A | 0.0109 | |
| 180 | T | A | 0.0000 | |
| 181 | N | A | -0.8435 | |
| 182 | L | A | 0.0157 | |
| 183 | L | A | 0.0000 | |
| 184 | Y | A | 0.1807 | |
| 185 | S | A | 0.0000 | |
| 186 | L | A | 0.0000 | |
| 187 | E | A | -0.2593 | |
| 188 | G | A | 0.0000 | |
| 189 | A | A | -0.0382 | mutated: LA189A |
| 190 | G | A | -0.6444 | |
| 191 | D | A | -1.8041 | |
| 192 | L | A | -0.2778 | |
| 193 | E | A | -0.9866 | |
| 194 | W | A | -0.3945 | |
| 195 | E | A | -1.9026 | |
| 196 | R | A | -0.9093 | |
| 197 | L | A | 0.0000 | |
| 198 | L | A | -0.0135 | |
| 199 | K | A | -1.6101 | |
| 200 | L | A | -0.1246 | |
| 201 | Q | A | -0.1002 | |
| 202 | S | A | 0.0000 | |
| 203 | G | A | -0.5192 | |
| 204 | N | A | -0.3739 | |
| 205 | G | A | 0.0000 | |
| 206 | S | A | 0.0000 | |
| 207 | F | A | 0.0000 | |
| 208 | L | A | 0.0000 | |
| 209 | T | A | 0.0000 | |
| 210 | S | A | 0.0000 | |
| 211 | P | A | 0.0000 | |
| 212 | S | A | 0.0000 | |
| 213 | S | A | 0.0000 | |
| 214 | T | A | 0.0000 | |
| 215 | A | A | 0.0000 | |
| 216 | A | A | 0.0060 | |
| 217 | V | A | 0.0000 | |
| 218 | L | A | 0.0000 | |
| 219 | A | A | -0.1327 | mutated: MA219A |
| 220 | H | A | -0.9856 | |
| 221 | T | A | -0.5056 | |
| 222 | K | A | -1.7503 | |
| 223 | D | A | -0.8927 | |
| 224 | E | A | -2.1721 | |
| 225 | K | A | -2.1697 | |
| 226 | C | A | 0.0000 | |
| 227 | L | A | -0.0978 | |
| 228 | K | A | -1.8064 | |
| 229 | Y | A | 0.0000 | |
| 230 | I | A | 0.0000 | |
| 231 | E | A | -1.5500 | |
| 232 | N | A | -1.2992 | |
| 233 | A | A | 0.0000 | |
| 234 | L | A | -0.1019 | |
| 235 | K | A | -1.8515 | |
| 236 | N | A | -1.3208 | |
| 237 | C | A | -0.4029 | |
| 238 | D | A | -1.7708 | |
| 239 | G | A | 0.0000 | |
| 240 | G | A | 0.0000 | |
| 241 | A | A | 0.0000 | |
| 242 | P | A | 0.0000 | |
| 243 | H | A | 0.0000 | |
| 244 | T | A | -0.0074 | |
| 245 | Y | A | 0.0000 | |
| 246 | P | A | 0.0000 | |
| 247 | V | A | 0.0000 | |
| 248 | D | A | 0.0000 | |
| 249 | I | A | 0.0000 | |
| 250 | F | A | 0.2114 | |
| 251 | S | A | 0.0000 | |
| 252 | R | A | 0.0000 | |
| 253 | L | A | 0.0000 | |
| 254 | W | A | 0.0000 | |
| 255 | A | A | 0.0000 | |
| 256 | I | A | 0.0000 | |
| 257 | D | A | 0.0000 | |
| 258 | R | A | 0.0000 | |
| 259 | L | A | 0.0000 | |
| 260 | Q | A | -0.2105 | |
| 261 | R | A | 0.0000 | |
| 262 | L | A | 0.0000 | |
| 263 | G | A | -0.0471 | |
| 264 | I | A | 0.0000 | |
| 265 | S | A | -0.1187 | |
| 266 | R | A | -0.2793 | |
| 267 | F | A | 0.3717 | |
| 268 | F | A | 0.0000 | |
| 269 | Q | A | -1.3764 | |
| 270 | H | A | -1.2056 | |
| 271 | E | A | 0.0000 | |
| 272 | I | A | 0.0000 | |
| 273 | K | A | -1.6185 | |
| 274 | Y | A | 0.1536 | |
| 275 | F | A | 0.0000 | |
| 276 | L | A | 0.0000 | |
| 277 | D | A | -0.6383 | |
| 278 | H | A | -0.3079 | |
| 279 | I | A | 0.0000 | |
| 280 | E | A | -1.1712 | |
| 281 | S | A | -0.3755 | |
| 282 | V | A | 0.2339 | |
| 283 | W | A | 0.0302 | |
| 284 | E | A | -1.5543 | |
| 285 | E | A | -2.0511 | |
| 286 | T | A | -0.3447 | |
| 287 | G | A | 0.0000 | |
| 288 | V | A | 0.0000 | |
| 289 | F | A | 0.2168 | |
| 290 | S | A | 0.0431 | |
| 291 | G | A | 0.0000 | |
| 292 | R | A | -0.7822 | |
| 293 | Y | A | 0.7699 | |
| 294 | T | A | -0.1448 | |
| 295 | K | A | -1.7014 | |
| 296 | F | A | 0.0000 | |
| 297 | S | A | 0.0000 | |
| 298 | D | A | 0.0000 | |
| 299 | I | A | 0.0000 | |
| 300 | D | A | -0.1955 | |
| 301 | D | A | 0.0000 | |
| 302 | T | A | 0.0000 | |
| 303 | S | A | 0.0000 | |
| 304 | M | A | 0.0000 | |
| 305 | G | A | 0.0000 | |
| 306 | V | A | 0.0000 | |
| 307 | R | A | 0.0000 | |
| 308 | L | A | 0.0000 | |
| 309 | L | A | 0.0000 | |
| 310 | K | A | 0.0000 | |
| 311 | M | A | 0.2317 | |
| 312 | H | A | -0.1501 | |
| 313 | G | A | -0.0448 | |
| 314 | Y | A | -0.1244 | |
| 315 | D | A | -1.7191 | |
| 316 | V | A | -0.4442 | |
| 317 | D | A | -1.5971 | |
| 318 | P | A | 0.0000 | |
| 319 | N | A | -0.7760 | |
| 320 | V | A | 0.0000 | |
| 321 | L | A | 0.0000 | |
| 322 | K | A | -1.7026 | |
| 323 | H | A | -0.4905 | |
| 324 | F | A | 0.0000 | |
| 325 | K | A | -0.8742 | |
| 326 | Q | A | -0.9242 | |
| 327 | Q | A | -1.6306 | |
| 328 | D | A | -2.0410 | |
| 329 | G | A | -0.7365 | |
| 330 | K | A | -1.2469 | |
| 331 | F | A | 0.0000 | |
| 332 | A | A | 0.0000 | |
| 333 | C | A | 0.0000 | |
| 334 | Y | A | 0.3077 | |
| 335 | I | A | 0.4535 | |
| 336 | G | A | -0.3990 | |
| 337 | Q | A | -0.2435 | |
| 338 | S | A | -0.1597 | |
| 339 | V | A | 0.2726 | |
| 340 | E | A | -0.4520 | |
| 341 | S | A | 0.0000 | |
| 342 | A | A | 0.0000 | |
| 343 | S | A | 0.0000 | |
| 344 | P | A | 0.0000 | |
| 345 | M | A | 0.0000 | |
| 346 | Y | A | 0.0000 | |
| 347 | N | A | 0.0000 | |
| 348 | L | A | 0.0000 | |
| 349 | Y | A | 0.0000 | |
| 350 | R | A | -0.1853 | |
| 351 | A | A | 0.0000 | |
| 352 | A | A | 0.0000 | |
| 353 | Q | A | 0.0000 | |
| 354 | L | A | 0.0000 | |
| 355 | R | A | 0.0000 | |
| 356 | F | A | 0.0000 | |
| 357 | P | A | -0.2014 | |
| 358 | G | A | -0.5341 | |
| 359 | E | A | -0.6687 | |
| 360 | E | A | -1.8659 | |
| 361 | V | A | 0.0000 | |
| 362 | L | A | 0.0000 | |
| 363 | E | A | -0.8305 | |
| 364 | E | A | -0.8275 | |
| 365 | A | A | 0.0000 | |
| 366 | T | A | 0.0000 | |
| 367 | K | A | -1.2963 | |
| 368 | F | A | 0.0318 | |
| 369 | A | A | 0.0000 | |
| 370 | F | A | 0.0629 | |
| 371 | N | A | -0.8149 | |
| 372 | F | A | 0.0747 | |
| 373 | L | A | 0.0000 | |
| 374 | Q | A | -0.9070 | |
| 375 | E | A | -1.3344 | |
| 376 | M | A | -0.2186 | |
| 377 | L | A | 0.3637 | |
| 378 | V | A | 1.5807 | |
| 379 | K | A | -1.2557 | |
| 380 | D | A | -2.3226 | |
| 381 | R | A | -2.1477 | |
| 382 | L | A | 0.0000 | |
| 383 | Q | A | -0.4619 | |
| 384 | E | A | 0.0000 | |
| 385 | R | A | -0.5981 | |
| 386 | W | A | 0.1362 | |
| 387 | V | A | 0.0000 | |
| 388 | I | A | 0.2458 | |
| 389 | S | A | -0.3210 | |
| 390 | D | A | -1.8868 | |
| 391 | H | A | -0.7897 | |
| 392 | L | A | 0.2202 | |
| 393 | F | A | 0.6890 | |
| 394 | D | A | -1.2873 | |
| 395 | E | A | -0.4015 | |
| 396 | I | A | 0.0000 | |
| 397 | K | A | -0.8499 | |
| 398 | L | A | 0.1612 | |
| 399 | G | A | 0.0000 | |
| 400 | L | A | 0.0000 | |
| 401 | K | A | -1.6795 | |
| 402 | M | A | -0.2044 | |
| 403 | P | A | 0.0160 | |
| 404 | W | A | 0.1725 | |
| 405 | Y | A | 0.0000 | |
| 406 | A | A | 0.0000 | |
| 407 | T | A | 0.0000 | |
| 408 | L | A | 0.0000 | |
| 409 | P | A | -0.1343 | |
| 410 | R | A | 0.0000 | |
| 411 | V | A | 0.0000 | |
| 412 | E | A | -0.6094 | |
| 413 | A | A | 0.0000 | |
| 414 | A | A | 0.0000 | |
| 415 | Y | A | 0.1934 | |
| 416 | Y | A | 0.0000 | |
| 417 | L | A | 0.0000 | |
| 418 | D | A | -1.6123 | |
| 419 | H | A | 0.0000 | |
| 420 | Y | A | 0.0000 | |
| 421 | A | A | 0.0126 | |
| 422 | G | A | 0.0000 | |
| 423 | S | A | -0.2212 | |
| 424 | G | A | -0.4911 | |
| 425 | D | A | 0.0000 | |
| 426 | V | A | 0.0000 | |
| 427 | W | A | 0.0000 | |
| 428 | I | A | 0.0000 | |
| 429 | G | A | 0.0000 | |
| 430 | K | A | 0.0000 | |
| 431 | S | A | 0.0000 | |
| 432 | F | A | 0.0000 | |
| 433 | Y | A | 0.0507 | |
| 434 | R | A | -0.4458 | |
| 435 | M | A | 0.0000 | |
| 436 | P | A | -0.0823 | |
| 437 | E | A | 0.0000 | |
| 438 | I | A | 0.0000 | |
| 439 | S | A | 0.0000 | |
| 440 | N | A | 0.0000 | |
| 441 | D | A | -1.8068 | |
| 442 | T | A | -0.3323 | |
| 443 | Y | A | 0.0000 | |
| 444 | K | A | -0.8335 | |
| 445 | E | A | -1.8789 | |
| 446 | L | A | 0.0000 | |
| 447 | A | A | 0.0000 | |
| 448 | I | A | 0.2653 | |
| 449 | L | A | 0.2220 | |
| 450 | D | A | 0.0000 | |
| 451 | F | A | 0.0000 | |
| 452 | N | A | -0.5394 | |
| 453 | R | A | -1.0077 | |
| 454 | C | A | 0.0000 | |
| 455 | Q | A | 0.0000 | |
| 456 | T | A | -0.1255 | |
| 457 | Q | A | -0.3126 | |
| 458 | H | A | 0.0000 | |
| 459 | Q | A | -0.2049 | |
| 460 | L | A | 1.4586 | |
| 461 | E | A | 0.0000 | |
| 462 | W | A | 0.4023 | |
| 463 | I | A | 1.6798 | |
| 464 | Q | A | -0.5482 | |
| 465 | M | A | 0.0000 | |
| 466 | Q | A | -0.6377 | |
| 467 | E | A | -1.9476 | |
| 468 | W | A | 0.0000 | |
| 469 | Y | A | 0.0000 | |
| 470 | D | A | -2.1171 | |
| 471 | R | A | -2.1621 | |
| 472 | C | A | 0.0000 | |
| 473 | S | A | -0.0451 | |
| 474 | L | A | 0.0000 | |
| 475 | S | A | -0.5389 | |
| 476 | E | A | -1.8580 | |
| 477 | F | A | 0.0000 | |
| 478 | G | A | -0.4663 | |
| 479 | I | A | 0.0000 | |
| 480 | S | A | -0.3269 | |
| 481 | K | A | -1.3431 | |
| 482 | R | A | -2.0860 | |
| 483 | E | A | -0.6907 | |
| 484 | L | A | 0.0000 | |
| 485 | L | A | 0.1398 | |
| 486 | R | A | -0.2355 | |
| 487 | S | A | 0.0000 | |
| 488 | Y | A | 0.0000 | |
| 489 | F | A | 0.0000 | |
| 490 | L | A | 0.0000 | |
| 491 | A | A | 0.0000 | |
| 492 | A | A | 0.0000 | |
| 493 | A | A | 0.0000 | |
| 494 | T | A | -0.0069 | |
| 495 | I | A | 0.0000 | |
| 496 | F | A | 0.1590 | |
| 497 | E | A | -0.1769 | |
| 498 | P | A | -0.3958 | |
| 499 | E | A | -1.9342 | |
| 500 | R | A | -0.9432 | |
| 501 | T | A | -0.2551 | |
| 502 | Q | A | -0.7038 | |
| 503 | E | A | 0.0000 | |
| 504 | R | A | 0.0000 | |
| 505 | L | A | 0.1656 | |
| 506 | L | A | 0.0000 | |
| 507 | W | A | 0.0000 | |
| 508 | A | A | 0.0000 | |
| 509 | K | A | -0.2061 | |
| 510 | T | A | 0.0000 | |
| 511 | R | A | -0.2669 | |
| 512 | I | A | 0.0000 | |
| 513 | L | A | 0.0000 | |
| 514 | S | A | 0.0000 | |
| 515 | K | A | -0.7310 | |
| 516 | M | A | 0.0000 | |
| 517 | I | A | 0.0000 | |
| 518 | T | A | -0.0286 | |
| 519 | S | A | -0.0703 | |
| 520 | F | A | 0.0000 | |
| 521 | V | A | 0.7334 | |
| 522 | N | A | -0.9384 | |
| 523 | I | A | 0.6257 | |
| 524 | S | A | -0.1358 | |
| 525 | G | A | -0.5096 | |
| 526 | T | A | -0.1234 | |
| 527 | T | A | -0.0301 | |
| 528 | L | A | 0.1956 | |
| 529 | S | A | 0.1107 | |
| 530 | L | A | 1.1865 | |
| 531 | D | A | -1.4608 | |
| 532 | Y | A | -0.2791 | |
| 533 | N | A | -1.1667 | |
| 534 | F | A | -0.1498 | |
| 535 | N | A | -1.2453 | |
| 536 | G | A | -0.2091 | |
| 537 | L | A | 0.6249 | |
| 538 | D | A | -1.9450 | |
| 539 | E | A | -2.0571 | |
| 540 | I | A | 0.2177 | |
| 541 | I | A | 0.4431 | |
| 542 | S | A | -0.1310 | |
| 543 | A | A | 0.0689 | |
| 544 | N | A | 0.0000 | |
| 545 | E | A | -2.1403 | |
| 546 | D | A | -2.1534 | |
| 547 | Q | A | -0.6195 | |
| 548 | G | A | -0.4516 | |
| 549 | L | A | 0.2001 | |
| 550 | A | A | 0.0000 | |
| 551 | G | A | -0.0855 | |
| 552 | T | A | -0.0349 | |
| 553 | L | A | 0.0000 | |
| 554 | L | A | 0.0000 | |
| 555 | A | A | 0.0189 | |
| 556 | T | A | 0.0000 | |
| 557 | F | A | 0.0000 | |
| 558 | H | A | -0.4877 | |
| 559 | Q | A | -0.5411 | |
| 560 | L | A | 0.0000 | |
| 561 | L | A | 0.0000 | |
| 562 | D | A | -1.8728 | |
| 563 | G | A | -0.7513 | |
| 564 | F | A | -0.2180 | |
| 565 | D | A | -1.4693 | |
| 566 | I | A | 1.5070 | |
| 567 | Y | A | 1.5985 | |
| 568 | T | A | 0.2674 | |
| 569 | L | A | 0.0694 | |
| 570 | H | A | -1.0303 | |
| 571 | Q | A | -0.6532 | |
| 572 | L | A | 0.0000 | |
| 573 | K | A | -1.2820 | |
| 574 | H | A | -1.1305 | |
| 575 | V | A | 0.0000 | |
| 576 | W | A | 0.0000 | |
| 577 | S | A | -0.2074 | |
| 578 | Q | A | -0.5964 | |
| 579 | W | A | 0.0000 | |
| 580 | F | A | 0.6316 | |
| 581 | M | A | 1.0744 | |
| 582 | K | A | -0.2160 | |
| 583 | V | A | -0.0220 | |
| 584 | Q | A | -1.3660 | |
| 585 | Q | A | -1.5334 | |
| 586 | G | A | -1.0074 | |
| 587 | E | A | -1.9172 | |
| 588 | G | A | -0.3967 | |
| 589 | S | A | -0.2030 | |
| 590 | G | A | -0.1499 | |
| 591 | G | A | 0.0000 | |
| 592 | E | A | 0.0000 | |
| 593 | D | A | -0.2116 | |
| 594 | A | A | 0.0000 | |
| 595 | V | A | 0.0000 | |
| 596 | L | A | 0.0000 | |
| 597 | L | A | 0.0000 | |
| 598 | A | A | 0.0000 | |
| 599 | N | A | 0.0000 | |
| 600 | T | A | 0.0000 | |
| 601 | L | A | 0.0000 | |
| 602 | N | A | 0.0000 | |
| 603 | I | A | 0.0000 | |
| 604 | C | A | 0.1380 | |
| 605 | A | A | -0.0255 | |
| 606 | G | A | -0.4015 | |
| 607 | L | A | 0.1185 | |
| 608 | N | A | -0.9194 | |
| 609 | E | A | -1.9900 | |
| 610 | D | A | -0.3039 | |
| 611 | V | A | 1.8033 | |
| 612 | L | A | 1.0835 | |
| 613 | S | A | -0.1248 | |
| 614 | N | A | -0.5895 | |
| 615 | N | A | -1.3696 | |
| 616 | E | A | -0.4429 | |
| 617 | Y | A | 0.0000 | |
| 618 | T | A | -0.0542 | |
| 619 | A | A | -0.0177 | |
| 620 | L | A | 0.0000 | |
| 621 | S | A | -0.0546 | |
| 622 | T | A | -0.0409 | |
| 623 | L | A | 0.1879 | |
| 624 | T | A | 0.0000 | |
| 625 | N | A | -0.4552 | |
| 626 | K | A | -1.4383 | |
| 627 | I | A | 0.0000 | |
| 628 | C | A | 0.0000 | |
| 629 | N | A | -0.5311 | |
| 630 | R | A | -0.8501 | |
| 631 | L | A | 0.0000 | |
| 632 | A | A | -0.1306 | |
| 633 | Q | A | -0.5384 | |
| 634 | I | A | 0.0000 | |
| 635 | Q | A | -0.9197 | |
| 636 | D | A | -2.0950 | |
| 637 | N | A | -1.9014 | |
| 638 | K | A | -1.6231 | |
| 639 | I | A | 1.6793 | |
| 640 | L | A | 0.4624 | |
| 641 | Q | A | -0.9377 | |
| 642 | V | A | 0.4949 | |
| 643 | V | A | 0.6294 | |
| 644 | D | A | -1.2352 | |
| 645 | G | A | -0.2802 | |
| 646 | S | A | -0.0563 | |
| 647 | I | A | 0.0000 | |
| 648 | K | A | -1.7488 | |
| 649 | D | A | -0.8882 | |
| 650 | K | A | -2.0812 | |
| 651 | E | A | -2.1302 | |
| 652 | L | A | 0.0000 | |
| 653 | E | A | 0.0000 | |
| 654 | Q | A | -0.8685 | |
| 655 | D | A | -0.3283 | |
| 656 | M | A | 0.0000 | |
| 657 | Q | A | 0.0000 | |
| 658 | A | A | 0.0148 | |
| 659 | L | A | 0.0000 | |
| 660 | V | A | 0.0000 | |
| 661 | K | A | -0.6528 | |
| 662 | L | A | 0.1408 | |
| 663 | V | A | 0.0000 | |
| 664 | L | A | 0.0000 | |
| 665 | Q | A | -0.2622 | |
| 666 | E | A | -0.9565 | |
| 667 | N | A | -1.4830 | |
| 668 | G | A | -0.7112 | |
| 669 | G | A | -0.2318 | |
| 670 | A | A | 0.0429 | |
| 671 | V | A | 0.0000 | |
| 672 | D | A | -0.6524 | |
| 673 | R | A | -0.7443 | |
| 674 | N | A | -1.3835 | |
| 675 | I | A | 0.0000 | |
| 676 | R | A | 0.0000 | |
| 677 | H | A | -0.4933 | |
| 678 | T | A | -0.0749 | |
| 679 | F | A | 0.0000 | |
| 680 | L | A | 0.0000 | |
| 681 | S | A | -0.0309 | |
| 682 | V | A | 0.0000 | |
| 683 | S | A | 0.0000 | |
| 684 | K | A | -0.1682 | |
| 685 | T | A | 0.0000 | |
| 686 | F | A | 0.0000 | |
| 687 | Y | A | 0.0000 | |
| 688 | Y | A | 0.0000 | |
| 689 | D | A | -0.2647 | |
| 690 | A | A | -0.0510 | |
| 691 | Y | A | 0.2810 | |
| 692 | H | A | 0.0000 | |
| 693 | D | A | -1.9727 | |
| 694 | D | A | -1.6598 | |
| 695 | E | A | -2.0046 | |
| 696 | T | A | -0.3514 | |
| 697 | T | A | 0.0000 | |
| 698 | D | A | -0.1040 | |
| 699 | L | A | 1.0894 | |
| 700 | H | A | 0.0000 | |
| 701 | I | A | 0.0000 | |
| 702 | F | A | 1.3474 | |
| 703 | K | A | -0.2125 | |
| 704 | V | A | 0.0000 | |
| 705 | L | A | 0.0000 | |
| 706 | F | A | 0.2194 | |
| 707 | R | A | -1.8423 | |
| 708 | P | A | -0.5477 | |
| 709 | V | A | 0.4875 | |
| 710 | V | A | 1.8113 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine