Project name: 7f8f2a8c372ce9f

Chain sequence(s)	A: FKGH; C: FKGH; B: FKGH; E: FKGH; D: FKGH; G: FKGH; F: FKGH; I: FKGH; H: FKGH; K: FKGH; J: FKGH; M: FKGH; L: FKGH; O: FKGH; N: FKGH; Q: FKGH; P: FKGH; S: FKGH; R: FKGH; T: FKGH
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,M,L,O,N,Q,P,S,R,T
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:26)
[INFO]       Main:     Simulation completed successfully.                                          (00:04:30)

• Minimal score value: -2.7252
• Maximal score value: 3.17
• Average score: -0.4375
• Total score value: -34.996

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	F	A	2.1290
2	K	A	-0.9763
3	G	A	-0.7836
4	H	A	-1.8043
1	F	B	2.3199
2	K	B	-0.4399
3	G	B	-0.5126
4	H	B	-2.0505
1	F	C	2.5089
2	K	C	-0.2343
3	G	C	-0.6070
4	H	C	-1.7764
1	F	D	2.4498
2	K	D	-0.4838
3	G	D	-1.0033
4	H	D	-1.8949
1	F	E	2.0416
2	K	E	-0.6547
3	G	E	-1.4475
4	H	E	-2.2811
1	F	F	2.3609
2	K	F	-0.1845
3	G	F	-0.9187
4	H	F	-1.4908
1	F	G	2.6953
2	K	G	0.1396
3	G	G	-0.7212
4	H	G	-1.9271
1	F	H	3.1700
2	K	H	0.3489
3	G	H	-0.6122
4	H	H	-1.8199
1	F	I	2.8390
2	K	I	0.1887
3	G	I	-0.7563
4	H	I	-1.9280
1	F	J	2.1481
2	K	J	-0.3855
3	G	J	-1.2125
4	H	J	-2.3313
1	F	K	1.1105
2	K	K	-1.6861
3	G	K	-1.7367
4	H	K	-2.0954
1	F	L	1.4017
2	K	L	-1.2129
3	G	L	-1.4955
4	H	L	-2.0007
1	F	M	1.0824
2	K	M	-1.9666
3	G	M	-2.2789
4	H	M	-2.7252
1	F	N	1.4697
2	K	N	-0.8985
3	G	N	-1.5940
4	H	N	-2.4527
1	F	O	2.4673
2	K	O	0.0565
3	G	O	-0.7553
4	H	O	-1.6397
1	F	P	2.0501
2	K	P	-0.2728
3	G	P	-1.0522
4	H	P	-2.0665
1	F	Q	1.6485
2	K	Q	-1.0337
3	G	Q	-0.8451
4	H	Q	-1.5005
1	F	R	1.7049
2	K	R	-1.1034
3	G	R	-1.3406
4	H	R	-1.7759
1	F	S	1.5085
2	K	S	-1.2591
3	G	S	-1.5957
4	H	S	-1.8348
1	F	T	1.0482
2	K	T	-1.5581
3	G	T	-1.3461
4	H	T	-1.5231