| Chain sequence(s) |
A: APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTCLPLKRMWHQALLRSGDKVR
C: APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTCLPLKRMWHQALLRSGDKVR B: MDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY D: MDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY input PDB |
| Selected Chain(s) | A,C,B,D |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | CR279C |
| Energy difference between WT (input) and mutated protein (by FoldX) | 0.11781 kcal/mol |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with all chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:01)
[INFO] FoldX: Building mutant model (00:04:38)
[INFO] FoldX: Starting FoldX energy minimalization (00:04:57)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:08:59)
[INFO] Main: Simulation completed successfully. (00:09:08)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | A | A | -1.2154 | |
| 2 | P | A | -1.4918 | |
| 3 | D | A | -2.6323 | |
| 4 | Q | A | -2.4264 | |
| 5 | D | A | 0.0000 | |
| 6 | E | A | -2.4590 | |
| 7 | I | A | 0.0000 | |
| 8 | Q | A | -2.9506 | |
| 9 | R | A | -2.9489 | |
| 10 | L | A | 0.0000 | |
| 11 | P | A | -0.4469 | |
| 12 | G | A | -0.3290 | |
| 13 | L | A | -1.0148 | |
| 14 | A | A | -1.2011 | |
| 15 | K | A | -2.5800 | |
| 16 | Q | A | -2.7801 | |
| 17 | P | A | -1.8362 | |
| 18 | S | A | -1.3817 | |
| 19 | F | A | 0.0000 | |
| 20 | R | A | -2.3860 | |
| 21 | Q | A | 0.0000 | |
| 22 | Y | A | 0.0000 | |
| 23 | S | A | 0.0000 | |
| 24 | G | A | 0.0000 | |
| 25 | Y | A | -0.2227 | |
| 26 | L | A | 0.0000 | |
| 27 | K | A | -1.4991 | |
| 28 | G | A | 0.0000 | |
| 29 | S | A | -1.0688 | |
| 30 | G | A | -1.2889 | |
| 31 | S | A | -1.6169 | |
| 32 | K | A | -1.4180 | |
| 33 | H | A | -0.9237 | |
| 34 | L | A | 0.0000 | |
| 35 | H | A | 0.0000 | |
| 36 | Y | A | 0.0000 | |
| 37 | W | A | 0.0000 | |
| 38 | F | A | 0.0000 | |
| 39 | V | A | 0.0000 | |
| 40 | E | A | -1.4919 | |
| 41 | S | A | 0.0000 | |
| 42 | Q | A | -1.6486 | |
| 43 | K | A | -2.9583 | |
| 44 | D | A | -3.5501 | |
| 45 | P | A | -2.9469 | |
| 46 | E | A | -3.7742 | |
| 47 | N | A | -3.2030 | |
| 48 | S | A | 0.0000 | |
| 49 | P | A | -1.5139 | |
| 50 | V | A | 0.0000 | |
| 51 | V | A | 0.0000 | |
| 52 | L | A | 0.0000 | |
| 53 | W | A | 0.0000 | |
| 54 | L | A | 0.0000 | |
| 55 | N | A | 0.0000 | |
| 56 | G | A | 0.0000 | |
| 57 | G | A | 0.0000 | |
| 58 | P | A | 0.0000 | |
| 59 | G | A | 0.0000 | |
| 60 | C | A | 0.0000 | |
| 61 | S | A | 0.0000 | |
| 62 | S | A | 0.0000 | |
| 63 | L | A | 0.0000 | |
| 64 | D | A | 0.0000 | |
| 65 | G | A | 0.0000 | |
| 66 | L | A | 0.0000 | |
| 67 | L | A | 0.0000 | |
| 68 | T | A | 0.1107 | |
| 69 | E | A | 0.0000 | |
| 70 | H | A | 0.0000 | |
| 71 | G | A | 0.0000 | |
| 72 | P | A | 0.0000 | |
| 73 | F | A | 0.0000 | |
| 74 | L | A | -0.0489 | |
| 75 | V | A | -0.0770 | |
| 76 | Q | A | -0.7260 | |
| 77 | P | A | -1.0220 | |
| 78 | D | A | -1.4100 | |
| 79 | G | A | 0.0000 | |
| 80 | V | A | 1.0150 | |
| 81 | T | A | 0.0226 | |
| 82 | L | A | 0.0000 | |
| 83 | E | A | -1.3967 | |
| 84 | Y | A | -0.5156 | |
| 85 | N | A | 0.0000 | |
| 86 | P | A | -0.0291 | |
| 87 | Y | A | 0.5131 | |
| 88 | S | A | 0.0000 | |
| 89 | W | A | 0.0000 | |
| 90 | N | A | 0.0000 | |
| 91 | L | A | -0.1670 | |
| 92 | I | A | -0.4180 | |
| 93 | A | A | 0.0000 | |
| 94 | N | A | 0.0000 | |
| 95 | V | A | 0.0000 | |
| 96 | L | A | 0.0000 | |
| 97 | Y | A | 0.0000 | |
| 98 | L | A | 0.0000 | |
| 99 | E | A | 0.0000 | |
| 100 | S | A | 0.0000 | |
| 101 | P | A | 0.0000 | |
| 102 | A | A | 0.0000 | |
| 103 | G | A | 0.0000 | |
| 104 | V | A | 0.0000 | |
| 105 | G | A | -0.4640 | |
| 106 | F | A | 0.0000 | |
| 107 | S | A | 0.0000 | |
| 108 | Y | A | -0.6175 | |
| 109 | S | A | 0.0000 | |
| 110 | D | A | -2.9869 | |
| 111 | D | A | -2.8768 | |
| 112 | K | A | -2.1003 | |
| 113 | F | A | 0.3662 | |
| 114 | Y | A | 0.5413 | |
| 115 | A | A | 0.1514 | |
| 116 | T | A | 0.0000 | |
| 117 | N | A | -1.2142 | |
| 118 | D | A | 0.0000 | |
| 119 | T | A | -0.8119 | |
| 120 | E | A | -1.5169 | |
| 121 | V | A | 0.0000 | |
| 122 | A | A | 0.0000 | |
| 123 | Q | A | -0.9809 | |
| 124 | S | A | 0.0000 | |
| 125 | N | A | 0.0000 | |
| 126 | F | A | -0.5693 | |
| 127 | E | A | -1.1016 | |
| 128 | A | A | 0.0000 | |
| 129 | L | A | 0.0000 | |
| 130 | Q | A | -1.5931 | |
| 131 | D | A | 0.0000 | |
| 132 | F | A | 0.0000 | |
| 133 | F | A | 0.0000 | |
| 134 | R | A | -2.3003 | |
| 135 | L | A | -1.2981 | |
| 136 | F | A | 0.0000 | |
| 137 | P | A | -2.0041 | |
| 138 | E | A | -2.9311 | |
| 139 | Y | A | 0.0000 | |
| 140 | K | A | -2.6783 | |
| 141 | N | A | -2.8565 | |
| 142 | N | A | -2.5513 | |
| 143 | K | A | -1.9083 | |
| 144 | L | A | 0.0000 | |
| 145 | F | A | 0.0000 | |
| 146 | L | A | 0.0000 | |
| 147 | T | A | 0.0000 | |
| 148 | G | A | 0.0000 | |
| 149 | E | A | 0.0000 | |
| 150 | S | A | 0.0000 | |
| 151 | Y | A | 0.0000 | |
| 152 | A | A | 0.0000 | |
| 153 | G | A | 0.0000 | |
| 154 | I | A | 0.0000 | |
| 155 | Y | A | 0.0000 | |
| 156 | I | A | 0.0000 | |
| 157 | P | A | 0.0000 | |
| 158 | T | A | 0.0000 | |
| 159 | L | A | 0.0000 | |
| 160 | A | A | 0.0000 | |
| 161 | V | A | -0.0150 | |
| 162 | L | A | -0.0014 | |
| 163 | V | A | 0.0000 | |
| 164 | M | A | -0.7380 | |
| 165 | Q | A | -1.1280 | |
| 166 | D | A | -0.9363 | |
| 167 | P | A | -0.8213 | |
| 168 | S | A | -1.1040 | |
| 169 | M | A | 0.0000 | |
| 170 | N | A | -1.5388 | |
| 171 | L | A | 0.0000 | |
| 172 | Q | A | -1.2725 | |
| 173 | G | A | 0.0000 | |
| 174 | L | A | 0.0000 | |
| 175 | A | A | 0.0000 | |
| 176 | V | A | 0.0000 | |
| 177 | G | A | 0.0000 | |
| 178 | N | A | 0.0000 | |
| 179 | G | A | 0.0000 | |
| 180 | L | A | 0.0000 | |
| 181 | S | A | 0.0000 | |
| 182 | S | A | 0.0000 | |
| 183 | Y | A | 0.0000 | |
| 184 | E | A | -1.2101 | |
| 185 | Q | A | -0.4954 | |
| 186 | N | A | 0.0000 | |
| 187 | D | A | 0.0000 | |
| 188 | N | A | 0.0000 | |
| 189 | S | A | 0.0000 | |
| 190 | L | A | 0.0000 | |
| 191 | V | A | 0.0000 | |
| 192 | Y | A | 0.1902 | |
| 193 | F | A | 0.0000 | |
| 194 | A | A | 0.0000 | |
| 195 | Y | A | 0.0000 | |
| 196 | Y | A | 0.0000 | |
| 197 | H | A | 0.0000 | |
| 198 | G | A | 0.0000 | |
| 199 | L | A | 0.0000 | |
| 200 | L | A | 0.0000 | |
| 201 | G | A | -0.9013 | |
| 202 | N | A | -1.0429 | |
| 203 | R | A | -2.1027 | |
| 204 | L | A | -0.9547 | |
| 205 | W | A | -0.6392 | |
| 206 | S | A | -0.9246 | |
| 207 | S | A | -1.0149 | |
| 208 | L | A | 0.0000 | |
| 209 | Q | A | -1.3212 | |
| 210 | T | A | -0.7266 | |
| 211 | H | A | -1.0566 | |
| 212 | C | A | 0.0000 | |
| 213 | C | A | -1.3947 | |
| 214 | S | A | -1.7650 | |
| 215 | Q | A | -2.9024 | |
| 216 | N | A | -3.2597 | |
| 217 | K | A | -2.7877 | |
| 218 | C | A | -1.5380 | |
| 219 | N | A | -1.3604 | |
| 220 | F | A | 0.0000 | |
| 221 | Y | A | -0.8357 | |
| 222 | D | A | -1.5938 | |
| 223 | N | A | -1.6741 | |
| 224 | K | A | -2.2192 | |
| 225 | D | A | -1.5692 | |
| 226 | L | A | -0.1220 | |
| 227 | E | A | -1.5051 | |
| 228 | C | A | 0.0000 | |
| 229 | V | A | -0.7389 | |
| 230 | T | A | -0.7544 | |
| 231 | N | A | -0.6000 | |
| 232 | L | A | 0.0000 | |
| 233 | Q | A | -0.8545 | |
| 234 | E | A | -0.7481 | |
| 235 | V | A | 0.0000 | |
| 236 | A | A | 0.0000 | |
| 237 | R | A | -0.4183 | |
| 238 | I | A | 0.0000 | |
| 239 | V | A | 0.0000 | |
| 240 | G | A | 0.0000 | |
| 241 | N | A | 0.0000 | |
| 242 | S | A | 0.0000 | |
| 243 | G | A | 0.0000 | |
| 244 | L | A | 0.0000 | |
| 245 | N | A | 0.0000 | |
| 246 | I | A | 0.0000 | |
| 247 | Y | A | 0.0000 | |
| 248 | N | A | -0.1528 | |
| 249 | L | A | 0.0000 | |
| 250 | Y | A | 0.0857 | |
| 251 | A | A | -0.1273 | |
| 252 | P | A | -0.3291 | |
| 253 | C | A | 0.0000 | |
| 254 | A | A | -0.5968 | |
| 255 | G | A | -0.9087 | |
| 256 | G | A | 0.0000 | |
| 257 | V | A | -0.4404 | |
| 258 | P | A | -0.5347 | |
| 259 | S | A | -0.7535 | |
| 260 | H | A | -0.9436 | |
| 261 | F | A | -0.0326 | |
| 262 | R | A | -1.2968 | |
| 263 | Y | A | -0.3125 | |
| 264 | E | A | -1.4294 | |
| 265 | K | A | -2.5695 | |
| 266 | D | A | -2.5683 | |
| 267 | T | A | -1.5273 | |
| 268 | V | A | -1.0989 | |
| 269 | V | A | -0.7059 | |
| 270 | V | A | 0.0000 | |
| 271 | Q | A | -0.8499 | |
| 272 | D | A | 0.0000 | |
| 273 | L | A | 0.0000 | |
| 274 | G | A | -0.3185 | |
| 275 | N | A | 0.0000 | |
| 276 | I | A | 0.0000 | |
| 277 | F | A | 0.0000 | |
| 278 | T | A | -0.1074 | |
| 279 | C | A | -0.2470 | |
| 280 | L | A | 0.0000 | |
| 281 | P | A | -0.6875 | |
| 282 | L | A | 0.0000 | |
| 283 | K | A | -1.5754 | |
| 284 | R | A | -1.8541 | |
| 285 | M | A | -1.0228 | |
| 286 | W | A | -0.7765 | |
| 287 | H | A | -1.4274 | |
| 288 | Q | A | -1.0969 | |
| 289 | A | A | -0.2783 | |
| 290 | L | A | 1.0340 | |
| 291 | L | A | 0.8215 | |
| 292 | R | A | -1.2732 | |
| 293 | S | A | -1.2394 | |
| 294 | G | A | -1.6775 | |
| 295 | D | A | -2.8220 | |
| 296 | K | A | -2.4397 | |
| 297 | V | A | -0.5467 | |
| 298 | R | A | -1.7646 | |
| 1 | M | B | -0.5340 | |
| 2 | D | B | -1.0276 | |
| 3 | P | B | 0.0000 | |
| 4 | P | B | -0.5085 | |
| 5 | C | B | -0.4374 | |
| 6 | T | B | -0.7901 | |
| 7 | N | B | -1.4498 | |
| 8 | T | B | 0.0000 | |
| 9 | T | B | -1.0352 | |
| 10 | A | B | -0.4771 | |
| 11 | A | B | 0.0000 | |
| 12 | S | B | 0.0000 | |
| 13 | T | B | -0.3392 | |
| 14 | Y | B | 0.0000 | |
| 15 | L | B | 0.0000 | |
| 16 | N | B | -0.7233 | |
| 17 | N | B | -0.3135 | |
| 18 | P | B | -0.5236 | |
| 19 | Y | B | 0.2255 | |
| 20 | V | B | 0.0000 | |
| 21 | R | B | 0.0000 | |
| 22 | K | B | -2.0103 | |
| 23 | A | B | -1.4678 | |
| 24 | L | B | 0.0000 | |
| 25 | N | B | -1.5016 | |
| 26 | I | B | 0.0000 | |
| 27 | P | B | -1.7059 | |
| 28 | E | B | -2.9173 | |
| 29 | Q | B | -2.1987 | |
| 30 | L | B | -1.3194 | |
| 31 | P | B | -1.3964 | |
| 32 | Q | B | -1.8604 | |
| 33 | W | B | 0.0000 | |
| 34 | D | B | -0.9184 | |
| 35 | M | B | 0.0000 | |
| 36 | C | B | 0.0000 | |
| 37 | N | B | 0.5575 | |
| 38 | F | B | 1.2975 | |
| 39 | L | B | 2.0503 | |
| 40 | V | B | 0.0000 | |
| 41 | N | B | 0.7229 | |
| 42 | L | B | 1.2193 | |
| 43 | Q | B | -0.2094 | |
| 44 | Y | B | 0.0000 | |
| 45 | R | B | -1.9728 | |
| 46 | R | B | -1.2780 | |
| 47 | L | B | -0.0998 | |
| 48 | Y | B | -0.5441 | |
| 49 | R | B | -1.7526 | |
| 50 | S | B | -1.0807 | |
| 51 | M | B | 0.0000 | |
| 52 | N | B | -0.7741 | |
| 53 | S | B | -0.4284 | |
| 54 | Q | B | 0.0000 | |
| 55 | Y | B | 0.0000 | |
| 56 | L | B | -0.2101 | |
| 57 | K | B | -0.9523 | |
| 58 | L | B | 0.0000 | |
| 59 | L | B | 0.0000 | |
| 60 | S | B | -1.0595 | |
| 61 | S | B | -1.4188 | |
| 62 | Q | B | -2.3658 | |
| 63 | K | B | -2.5376 | |
| 64 | Y | B | 0.0000 | |
| 65 | Q | B | -1.3558 | |
| 66 | I | B | 0.0000 | |
| 67 | L | B | 0.0000 | |
| 68 | L | B | 0.0000 | |
| 69 | Y | B | 0.0000 | |
| 70 | N | B | 0.0000 | |
| 71 | G | B | 0.0000 | |
| 72 | D | B | 0.0000 | |
| 73 | V | B | 0.0000 | |
| 74 | D | B | 0.0000 | |
| 75 | M | B | 0.0000 | |
| 76 | A | B | 0.0000 | |
| 77 | C | B | 0.0000 | |
| 78 | N | B | 0.0000 | |
| 79 | F | B | 0.0000 | |
| 80 | M | B | 0.0000 | |
| 81 | G | B | 0.0000 | |
| 82 | D | B | 0.0000 | |
| 83 | E | B | 0.0000 | |
| 84 | W | B | 0.0432 | |
| 85 | F | B | 0.0000 | |
| 86 | V | B | 0.0000 | |
| 87 | D | B | -0.9442 | |
| 88 | S | B | -0.7052 | |
| 89 | L | B | 0.0000 | |
| 90 | N | B | -1.7483 | |
| 91 | Q | B | -1.8675 | |
| 92 | K | B | -2.4089 | |
| 93 | M | B | -1.7709 | |
| 94 | E | B | -2.2147 | |
| 95 | V | B | -1.2011 | |
| 96 | Q | B | -1.7444 | |
| 97 | R | B | -1.3214 | |
| 98 | R | B | -0.7205 | |
| 99 | P | B | -0.2942 | |
| 100 | W | B | 0.0000 | |
| 101 | L | B | -0.1932 | |
| 102 | V | B | 0.0000 | |
| 103 | K | B | -2.2230 | |
| 104 | Y | B | -1.3446 | |
| 105 | G | B | -1.8013 | |
| 106 | D | B | -2.4339 | |
| 107 | S | B | -1.6955 | |
| 108 | G | B | -1.8452 | |
| 109 | E | B | -2.0166 | |
| 110 | Q | B | 0.0000 | |
| 111 | I | B | 0.0000 | |
| 112 | A | B | 0.0000 | |
| 113 | G | B | 0.0000 | |
| 114 | F | B | 0.0000 | |
| 115 | V | B | 0.0000 | |
| 116 | K | B | 0.0000 | |
| 117 | E | B | -1.1393 | |
| 118 | F | B | 0.0000 | |
| 119 | S | B | 0.0000 | |
| 120 | H | B | -1.6306 | |
| 121 | I | B | 0.0000 | |
| 122 | A | B | 0.0000 | |
| 123 | F | B | 0.0000 | |
| 124 | L | B | 0.0000 | |
| 125 | T | B | 0.0000 | |
| 126 | I | B | 0.0000 | |
| 127 | K | B | -0.2859 | |
| 128 | G | B | -0.2410 | |
| 129 | A | B | 0.0000 | |
| 130 | G | B | 0.0000 | |
| 131 | H | B | 0.0000 | |
| 132 | M | B | -0.0779 | |
| 133 | V | B | 0.0000 | |
| 134 | P | B | 0.0000 | |
| 135 | T | B | -0.4016 | |
| 136 | D | B | -0.8765 | |
| 137 | K | B | -0.6789 | |
| 138 | P | B | -0.1660 | |
| 139 | L | B | 0.0771 | |
| 140 | A | B | 0.0000 | |
| 141 | A | B | 0.0000 | |
| 142 | F | B | 0.4074 | |
| 143 | T | B | 0.0177 | |
| 144 | M | B | 0.0000 | |
| 145 | F | B | 0.0000 | |
| 146 | S | B | -0.7087 | |
| 147 | R | B | -1.6543 | |
| 148 | F | B | 0.0000 | |
| 149 | L | B | -1.4380 | |
| 150 | N | B | -2.4795 | |
| 151 | K | B | -2.9889 | |
| 152 | Q | B | -2.5526 | |
| 153 | P | B | -1.3282 | |
| 154 | Y | B | -0.6015 | |
| 1 | A | C | -1.2418 | |
| 2 | P | C | -1.5887 | |
| 3 | D | C | -2.7795 | |
| 4 | Q | C | -2.5548 | |
| 5 | D | C | 0.0000 | |
| 6 | E | C | -2.7571 | |
| 7 | I | C | 0.0000 | |
| 8 | Q | C | -2.9743 | |
| 9 | R | C | -3.0294 | |
| 10 | L | C | 0.0000 | |
| 11 | P | C | -0.5196 | |
| 12 | G | C | -0.4017 | |
| 13 | L | C | 0.0000 | |
| 14 | A | C | -1.2829 | |
| 15 | K | C | -2.6382 | |
| 16 | Q | C | -2.7579 | |
| 17 | P | C | -1.7155 | |
| 18 | S | C | -1.2064 | |
| 19 | F | C | 0.0000 | |
| 20 | R | C | -1.7074 | |
| 21 | Q | C | 0.0000 | |
| 22 | Y | C | 0.0000 | |
| 23 | S | C | 0.0000 | |
| 24 | G | C | 0.0000 | |
| 25 | Y | C | -0.2505 | |
| 26 | L | C | 0.0000 | |
| 27 | K | C | -1.6688 | |
| 28 | G | C | 0.0000 | |
| 29 | S | C | -1.0864 | |
| 30 | G | C | -1.3075 | |
| 31 | S | C | -1.6457 | |
| 32 | K | C | -1.4621 | |
| 33 | H | C | -0.9798 | |
| 34 | L | C | 0.0000 | |
| 35 | H | C | 0.0000 | |
| 36 | Y | C | 0.0000 | |
| 37 | W | C | 0.0000 | |
| 38 | F | C | 0.0000 | |
| 39 | V | C | 0.0000 | |
| 40 | E | C | 0.0000 | |
| 41 | S | C | 0.0000 | |
| 42 | Q | C | -1.4708 | |
| 43 | K | C | -2.9103 | |
| 44 | D | C | -3.5103 | |
| 45 | P | C | -2.7723 | |
| 46 | E | C | -3.6655 | |
| 47 | N | C | -3.1718 | |
| 48 | S | C | 0.0000 | |
| 49 | P | C | -1.4600 | |
| 50 | V | C | 0.0000 | |
| 51 | V | C | 0.0000 | |
| 52 | L | C | 0.0000 | |
| 53 | W | C | 0.0000 | |
| 54 | L | C | 0.0000 | |
| 55 | N | C | 0.0000 | |
| 56 | G | C | 0.0000 | |
| 57 | G | C | 0.0000 | |
| 58 | P | C | 0.0000 | |
| 59 | G | C | 0.0000 | |
| 60 | C | C | 0.0000 | |
| 61 | S | C | 0.0000 | |
| 62 | S | C | 0.0000 | |
| 63 | L | C | 0.0000 | |
| 64 | D | C | -0.1287 | |
| 65 | G | C | 0.0000 | |
| 66 | L | C | 0.0000 | |
| 67 | L | C | 0.0000 | |
| 68 | T | C | 0.0335 | |
| 69 | E | C | 0.0000 | |
| 70 | H | C | 0.0000 | |
| 71 | G | C | 0.0000 | |
| 72 | P | C | 0.0000 | |
| 73 | F | C | 0.0000 | |
| 74 | L | C | -0.1108 | |
| 75 | V | C | -0.1584 | |
| 76 | Q | C | -0.8044 | |
| 77 | P | C | -1.0686 | |
| 78 | D | C | -1.4409 | |
| 79 | G | C | 0.0000 | |
| 80 | V | C | 0.9799 | |
| 81 | T | C | -0.0395 | |
| 82 | L | C | 0.0000 | |
| 83 | E | C | -1.4443 | |
| 84 | Y | C | -0.5279 | |
| 85 | N | C | 0.0000 | |
| 86 | P | C | -0.0179 | |
| 87 | Y | C | 0.5246 | |
| 88 | S | C | 0.0000 | |
| 89 | W | C | 0.0000 | |
| 90 | N | C | 0.0000 | |
| 91 | L | C | -0.1063 | |
| 92 | I | C | -0.3640 | |
| 93 | A | C | 0.0000 | |
| 94 | N | C | 0.0000 | |
| 95 | V | C | 0.0000 | |
| 96 | L | C | 0.0000 | |
| 97 | Y | C | 0.0000 | |
| 98 | L | C | 0.0000 | |
| 99 | E | C | 0.0000 | |
| 100 | S | C | 0.0000 | |
| 101 | P | C | 0.0000 | |
| 102 | A | C | 0.0000 | |
| 103 | G | C | 0.0000 | |
| 104 | V | C | 0.0000 | |
| 105 | G | C | -0.6513 | |
| 106 | F | C | 0.0000 | |
| 107 | S | C | 0.0000 | |
| 108 | Y | C | -0.6627 | |
| 109 | S | C | 0.0000 | |
| 110 | D | C | -2.9887 | |
| 111 | D | C | -2.8864 | |
| 112 | K | C | -2.1215 | |
| 113 | F | C | 0.3391 | |
| 114 | Y | C | 0.5243 | |
| 115 | A | C | 0.2748 | |
| 116 | T | C | 0.0000 | |
| 117 | N | C | -1.1465 | |
| 118 | D | C | 0.0000 | |
| 119 | T | C | -0.7771 | |
| 120 | E | C | -1.4902 | |
| 121 | V | C | 0.0000 | |
| 122 | A | C | 0.0000 | |
| 123 | Q | C | -0.9524 | |
| 124 | S | C | 0.0000 | |
| 125 | N | C | 0.0000 | |
| 126 | F | C | -0.5801 | |
| 127 | E | C | -1.1165 | |
| 128 | A | C | 0.0000 | |
| 129 | L | C | 0.0000 | |
| 130 | Q | C | -1.6354 | |
| 131 | D | C | 0.0000 | |
| 132 | F | C | 0.0000 | |
| 133 | F | C | 0.0000 | |
| 134 | R | C | -2.2841 | |
| 135 | L | C | -1.2702 | |
| 136 | F | C | 0.0000 | |
| 137 | P | C | -1.9049 | |
| 138 | E | C | -2.6477 | |
| 139 | Y | C | 0.0000 | |
| 140 | K | C | -2.6366 | |
| 141 | N | C | -2.7843 | |
| 142 | N | C | 0.0000 | |
| 143 | K | C | -1.9060 | |
| 144 | L | C | 0.0000 | |
| 145 | F | C | 0.0000 | |
| 146 | L | C | 0.0000 | |
| 147 | T | C | 0.0000 | |
| 148 | G | C | 0.0000 | |
| 149 | E | C | 0.0000 | |
| 150 | S | C | 0.0000 | |
| 151 | Y | C | 0.0000 | |
| 152 | A | C | 0.0000 | |
| 153 | G | C | 0.0000 | |
| 154 | I | C | 0.0000 | |
| 155 | Y | C | 0.0000 | |
| 156 | I | C | 0.0000 | |
| 157 | P | C | 0.0000 | |
| 158 | T | C | 0.0000 | |
| 159 | L | C | 0.0000 | |
| 160 | A | C | 0.0000 | |
| 161 | V | C | -0.0936 | |
| 162 | L | C | -0.0245 | |
| 163 | V | C | 0.0000 | |
| 164 | M | C | -0.7507 | |
| 165 | Q | C | -1.1422 | |
| 166 | D | C | -0.9561 | |
| 167 | P | C | -0.8254 | |
| 168 | S | C | -1.1232 | |
| 169 | M | C | 0.0000 | |
| 170 | N | C | -1.5292 | |
| 171 | L | C | 0.0000 | |
| 172 | Q | C | -1.2788 | |
| 173 | G | C | 0.0000 | |
| 174 | L | C | 0.0000 | |
| 175 | A | C | 0.0000 | |
| 176 | V | C | 0.0000 | |
| 177 | G | C | 0.0000 | |
| 178 | N | C | 0.0000 | |
| 179 | G | C | 0.0000 | |
| 180 | L | C | 0.0000 | |
| 181 | S | C | 0.0000 | |
| 182 | S | C | 0.0000 | |
| 183 | Y | C | 0.0000 | |
| 184 | E | C | -1.5112 | |
| 185 | Q | C | -0.5723 | |
| 186 | N | C | 0.0000 | |
| 187 | D | C | 0.0000 | |
| 188 | N | C | 0.0000 | |
| 189 | S | C | 0.0000 | |
| 190 | L | C | 0.0000 | |
| 191 | V | C | 0.0000 | |
| 192 | Y | C | 0.1882 | |
| 193 | F | C | 0.0000 | |
| 194 | A | C | 0.0000 | |
| 195 | Y | C | 0.0000 | |
| 196 | Y | C | 0.0000 | |
| 197 | H | C | 0.0000 | |
| 198 | G | C | 0.0000 | |
| 199 | L | C | 0.0000 | |
| 200 | L | C | 0.0000 | |
| 201 | G | C | -0.9206 | |
| 202 | N | C | -1.0627 | |
| 203 | R | C | -2.1613 | |
| 204 | L | C | -1.0655 | |
| 205 | W | C | 0.0000 | |
| 206 | S | C | -1.0828 | |
| 207 | S | C | -1.1607 | |
| 208 | L | C | 0.0000 | |
| 209 | Q | C | -1.6901 | |
| 210 | T | C | -0.9033 | |
| 211 | H | C | -1.1325 | |
| 212 | C | C | 0.0000 | |
| 213 | C | C | -1.5021 | |
| 214 | S | C | -1.8215 | |
| 215 | Q | C | -2.9519 | |
| 216 | N | C | -3.2623 | |
| 217 | K | C | -2.8148 | |
| 218 | C | C | -1.5922 | |
| 219 | N | C | -1.3151 | |
| 220 | F | C | 0.0000 | |
| 221 | Y | C | 0.0000 | |
| 222 | D | C | -1.9348 | |
| 223 | N | C | -1.8158 | |
| 224 | K | C | -2.3492 | |
| 225 | D | C | -1.4953 | |
| 226 | L | C | -0.1031 | |
| 227 | E | C | -1.4994 | |
| 228 | C | C | 0.0000 | |
| 229 | V | C | -0.9100 | |
| 230 | T | C | -0.7485 | |
| 231 | N | C | -0.6905 | |
| 232 | L | C | 0.0000 | |
| 233 | Q | C | -0.8788 | |
| 234 | E | C | -0.7418 | |
| 235 | V | C | 0.0000 | |
| 236 | A | C | 0.0000 | |
| 237 | R | C | -0.5460 | |
| 238 | I | C | 0.0000 | |
| 239 | V | C | 0.0000 | |
| 240 | G | C | -0.2407 | |
| 241 | N | C | 0.0000 | |
| 242 | S | C | -0.0972 | |
| 243 | G | C | 0.0000 | |
| 244 | L | C | 0.0000 | |
| 245 | N | C | -0.0498 | |
| 246 | I | C | 0.0000 | |
| 247 | Y | C | 0.1686 | |
| 248 | N | C | 0.0000 | |
| 249 | L | C | 0.0000 | |
| 250 | Y | C | 0.1342 | |
| 251 | A | C | -0.0784 | |
| 252 | P | C | -0.3314 | |
| 253 | C | C | 0.0000 | |
| 254 | A | C | -0.6110 | |
| 255 | G | C | -0.9226 | |
| 256 | G | C | 0.0000 | |
| 257 | V | C | -0.5252 | |
| 258 | P | C | -0.7973 | |
| 259 | S | C | -0.9571 | |
| 260 | H | C | -1.2437 | |
| 261 | F | C | -0.7971 | |
| 262 | R | C | -2.0480 | |
| 263 | Y | C | -1.1811 | |
| 264 | E | C | -2.9783 | |
| 265 | K | C | -3.2868 | |
| 266 | D | C | -2.9647 | |
| 267 | T | C | -1.9452 | |
| 268 | V | C | -1.3910 | |
| 269 | V | C | 0.0000 | |
| 270 | V | C | 0.0000 | |
| 271 | Q | C | -0.6413 | |
| 272 | D | C | 0.0000 | |
| 273 | L | C | 0.0000 | |
| 274 | G | C | -0.0875 | |
| 275 | N | C | 0.0000 | |
| 276 | I | C | 0.0000 | |
| 277 | F | C | 0.0000 | |
| 278 | T | C | -1.1383 | |
| 279 | R | C | -2.3628 | mutated: CR279C |
| 280 | L | C | 0.0000 | |
| 281 | P | C | -1.1361 | |
| 282 | L | C | 0.0000 | |
| 283 | K | C | -1.4684 | |
| 284 | R | C | -0.7744 | |
| 285 | M | C | -0.5099 | |
| 286 | W | C | -0.5603 | |
| 287 | H | C | -1.2888 | |
| 288 | Q | C | -1.1438 | |
| 289 | A | C | -0.3087 | |
| 290 | L | C | 0.8510 | |
| 291 | L | C | 0.8205 | |
| 292 | R | C | -1.2667 | |
| 293 | S | C | -1.3583 | |
| 294 | G | C | -1.6540 | |
| 295 | D | C | -2.6509 | |
| 296 | K | C | -2.4418 | |
| 297 | V | C | -0.5387 | |
| 298 | R | C | -1.7609 | |
| 1 | M | D | -0.8086 | |
| 2 | D | D | -1.3380 | |
| 3 | P | D | -0.7457 | |
| 4 | P | D | -0.6203 | |
| 5 | C | D | -0.5019 | |
| 6 | T | D | -0.8605 | |
| 7 | N | D | -1.5110 | |
| 8 | T | D | -1.0167 | |
| 9 | T | D | -1.1641 | |
| 10 | A | D | -0.5125 | |
| 11 | A | D | 0.0000 | |
| 12 | S | D | 0.0000 | |
| 13 | T | D | -0.4374 | |
| 14 | Y | D | 0.0000 | |
| 15 | L | D | 0.0000 | |
| 16 | N | D | -0.9262 | |
| 17 | N | D | -0.4127 | |
| 18 | P | D | -0.6225 | |
| 19 | Y | D | 0.1482 | |
| 20 | V | D | 0.0000 | |
| 21 | R | D | -1.4043 | |
| 22 | K | D | -2.1041 | |
| 23 | A | D | -1.5859 | |
| 24 | L | D | 0.0000 | |
| 25 | N | D | -1.6013 | |
| 26 | I | D | 0.0000 | |
| 27 | P | D | -1.7450 | |
| 28 | E | D | -2.9577 | |
| 29 | Q | D | -2.2108 | |
| 30 | L | D | -1.3740 | |
| 31 | P | D | -1.4958 | |
| 32 | Q | D | -2.0519 | |
| 33 | W | D | 0.0000 | |
| 34 | D | D | -1.5654 | |
| 35 | M | D | 0.0000 | |
| 36 | C | D | 0.0000 | |
| 37 | N | D | 0.2104 | |
| 38 | F | D | 0.9799 | |
| 39 | L | D | 1.7671 | |
| 40 | V | D | 0.0000 | |
| 41 | N | D | 0.7303 | |
| 42 | L | D | 1.4845 | |
| 43 | Q | D | 0.2490 | |
| 44 | Y | D | 0.0000 | |
| 45 | R | D | -1.8187 | |
| 46 | R | D | -1.2033 | |
| 47 | L | D | 0.0855 | |
| 48 | Y | D | -0.5327 | |
| 49 | R | D | -1.7617 | |
| 50 | S | D | -1.1113 | |
| 51 | M | D | 0.0000 | |
| 52 | N | D | -0.8423 | |
| 53 | S | D | -0.5204 | |
| 54 | Q | D | -0.4985 | |
| 55 | Y | D | 0.0000 | |
| 56 | L | D | -0.2730 | |
| 57 | K | D | -1.0323 | |
| 58 | L | D | 0.0000 | |
| 59 | L | D | 0.0000 | |
| 60 | S | D | -1.0721 | |
| 61 | S | D | -1.4267 | |
| 62 | Q | D | -2.3808 | |
| 63 | K | D | -2.5417 | |
| 64 | Y | D | 0.0000 | |
| 65 | Q | D | -1.3917 | |
| 66 | I | D | 0.0000 | |
| 67 | L | D | 0.0000 | |
| 68 | L | D | 0.0000 | |
| 69 | Y | D | 0.0000 | |
| 70 | N | D | 0.0000 | |
| 71 | G | D | 0.0000 | |
| 72 | D | D | 0.0000 | |
| 73 | V | D | 0.0000 | |
| 74 | D | D | 0.0000 | |
| 75 | M | D | 0.0000 | |
| 76 | A | D | 0.0000 | |
| 77 | C | D | 0.0000 | |
| 78 | N | D | 0.0000 | |
| 79 | F | D | 0.0000 | |
| 80 | M | D | 0.0000 | |
| 81 | G | D | 0.0000 | |
| 82 | D | D | 0.0000 | |
| 83 | E | D | 0.0000 | |
| 84 | W | D | 0.0210 | |
| 85 | F | D | 0.0000 | |
| 86 | V | D | 0.0000 | |
| 87 | D | D | -0.9759 | |
| 88 | S | D | -0.7261 | |
| 89 | L | D | 0.0000 | |
| 90 | N | D | -1.7545 | |
| 91 | Q | D | -1.8748 | |
| 92 | K | D | -2.4098 | |
| 93 | M | D | -1.7602 | |
| 94 | E | D | -2.2141 | |
| 95 | V | D | -1.2010 | |
| 96 | Q | D | -1.7439 | |
| 97 | R | D | -1.3253 | |
| 98 | R | D | -0.7251 | |
| 99 | P | D | -0.2927 | |
| 100 | W | D | 0.0000 | |
| 101 | L | D | -0.1875 | |
| 102 | V | D | 0.0000 | |
| 103 | K | D | -2.2085 | |
| 104 | Y | D | -1.3403 | |
| 105 | G | D | -1.7982 | |
| 106 | D | D | -2.4282 | |
| 107 | S | D | -1.6944 | |
| 108 | G | D | -1.8166 | |
| 109 | E | D | -1.9582 | |
| 110 | Q | D | 0.0000 | |
| 111 | I | D | 0.0000 | |
| 112 | A | D | 0.0000 | |
| 113 | G | D | 0.0000 | |
| 114 | F | D | 0.0000 | |
| 115 | V | D | 0.0000 | |
| 116 | K | D | 0.0000 | |
| 117 | E | D | -1.1471 | |
| 118 | F | D | 0.0000 | |
| 119 | S | D | -1.3900 | |
| 120 | H | D | -1.6614 | |
| 121 | I | D | 0.0000 | |
| 122 | A | D | 0.0000 | |
| 123 | F | D | 0.0000 | |
| 124 | L | D | 0.0000 | |
| 125 | T | D | 0.0000 | |
| 126 | I | D | 0.0000 | |
| 127 | K | D | -0.2752 | |
| 128 | G | D | -0.2094 | |
| 129 | A | D | 0.0000 | |
| 130 | G | D | 0.0000 | |
| 131 | H | D | 0.0000 | |
| 132 | M | D | -0.0636 | |
| 133 | V | D | 0.0000 | |
| 134 | P | D | 0.0000 | |
| 135 | T | D | -0.3716 | |
| 136 | D | D | -0.7976 | |
| 137 | K | D | -0.6453 | |
| 138 | P | D | -0.1440 | |
| 139 | L | D | 0.0954 | |
| 140 | A | D | 0.0000 | |
| 141 | A | D | 0.0000 | |
| 142 | F | D | 0.4196 | |
| 143 | T | D | 0.0233 | |
| 144 | M | D | 0.0000 | |
| 145 | F | D | 0.0000 | |
| 146 | S | D | -0.6804 | |
| 147 | R | D | -1.6097 | |
| 148 | F | D | 0.0000 | |
| 149 | L | D | 0.0000 | |
| 150 | N | D | -2.2761 | |
| 151 | K | D | -2.9039 | |
| 152 | Q | D | -2.4888 | |
| 153 | P | D | -1.2948 | |
| 154 | Y | D | -0.6077 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine