Project name: 82f3268b8e0981c

Chain sequence(s)	D: EIVLTQSPATLSLSPGERATLSCRASQSVYSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPFTFGPGTKVDIK; G: QVQLVESGGGVVQPGRSLRLSCAASGFIFSSYAMHWVRQAPGNGLEWVAFMSYDGSNKKYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDRGIAAGGNYYYYGMDVWGQGTTVTVSS
Selected Chain(s)	D,G
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:53)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:55)

• Minimal score value: -2.963
• Maximal score value: 1.9745
• Average score: -0.594
• Total score value: -139.0008

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	D	-1.4017
2	I	D	0.0000
3	V	D	0.9475
4	L	D	0.2331
5	T	D	-0.4877
6	Q	D	0.0000
7	S	D	-0.7602
8	P	D	-0.4536
9	A	D	-0.5203
10	T	D	-0.9328
11	L	D	-0.5115
12	S	D	-0.5712
13	L	D	-0.6125
14	S	D	-0.9826
15	P	D	-1.3743
16	G	D	-1.8727
17	E	D	-2.5461
18	R	D	-2.6648
19	A	D	0.0000
20	T	D	-0.5656
21	L	D	0.0000
22	S	D	-0.9300
23	C	D	0.0000
24	R	D	-2.2739
25	A	D	0.0000
26	S	D	-0.8726
27	Q	D	-1.1581
28	S	D	-0.6586
29	V	D	0.0000
30	Y	D	0.8996
31	S	D	0.2736
32	Y	D	0.5609
33	L	D	0.0000
34	A	D	0.0000
35	W	D	0.0000
36	Y	D	0.0000
37	Q	D	0.0000
38	Q	D	0.0000
39	K	D	-1.2779
40	P	D	-0.7803
41	G	D	-1.0469
42	Q	D	-1.2336
43	A	D	-0.8810
44	P	D	0.0000
45	R	D	-1.1439
46	L	D	0.0000
47	L	D	0.0000
48	I	D	0.0000
49	Y	D	-0.6438
50	D	D	-0.4862
51	A	D	0.0000
52	S	D	-1.3146
53	N	D	-1.9478
54	R	D	-2.1434
55	A	D	-1.3128
56	T	D	-0.8398
57	G	D	-0.6098
58	I	D	-0.5348
59	P	D	-0.4022
60	A	D	-0.4171
61	R	D	-0.8162
62	F	D	0.0000
63	S	D	-0.7663
64	G	D	-0.8646
65	S	D	-0.8799
66	G	D	-0.9993
67	S	D	-0.7025
68	G	D	-0.5152
69	T	D	-1.4041
70	D	D	-2.0654
71	F	D	0.0000
72	T	D	-0.8260
73	L	D	0.0000
74	T	D	-0.6034
75	I	D	0.0000
76	S	D	-1.4134
77	S	D	-1.7877
78	L	D	0.0000
79	E	D	-1.8982
80	P	D	-1.3458
81	E	D	-1.8816
82	D	D	0.0000
83	F	D	-0.8328
84	A	D	0.0000
85	V	D	0.0000
86	Y	D	0.0000
87	Y	D	0.0000
88	C	D	0.0000
89	Q	D	0.0000
90	Q	D	0.0000
91	R	D	0.0000
92	S	D	0.0000
93	N	D	-0.3131
94	W	D	0.0932
95	P	D	-0.3127
96	P	D	-0.3571
97	F	D	0.0000
98	T	D	0.1164
99	F	D	0.0000
100	G	D	0.0000
101	P	D	-0.5677
102	G	D	-0.7951
103	T	D	0.0000
104	K	D	-1.7625
105	V	D	0.0000
106	D	D	-0.7848
107	I	D	0.0704
108	K	D	-1.2051
1	Q	G	-1.0638
2	V	G	0.1670
3	Q	G	-0.6358
4	L	G	0.0000
5	V	G	0.5892
6	E	G	0.0000
7	S	G	-0.5753
8	G	G	-0.9713
9	G	G	-0.3803
10	G	G	0.4763
11	V	G	1.2918
12	V	G	0.0000
13	Q	G	-1.7852
14	P	G	-1.9307
15	G	G	-2.3247
16	R	G	-2.9630
17	S	G	-2.1925
18	L	G	-1.4486
19	R	G	-1.9818
20	L	G	0.0000
21	S	G	-0.4688
22	C	G	0.0000
23	A	G	-0.2747
24	A	G	0.0000
25	S	G	-0.0432
26	G	G	-0.0659
27	F	G	0.9294
28	I	G	1.9745
29	F	G	0.0000
30	S	G	0.1637
31	S	G	0.1786
32	Y	G	0.1771
33	A	G	0.0000
34	M	G	0.0000
35	H	G	0.0000
36	W	G	0.0000
37	V	G	0.0000
38	R	G	0.0000
39	Q	G	-0.7351
40	A	G	-1.0979
41	P	G	-0.8752
42	G	G	-1.2421
43	N	G	-1.7833
44	G	G	-1.1253
45	L	G	0.0000
46	E	G	-0.9965
47	W	G	0.0000
48	V	G	0.0000
49	A	G	0.0000
50	F	G	0.0000
51	M	G	0.0000
52	S	G	-0.8046
53	Y	G	-0.1680
54	D	G	-1.7537
55	G	G	-1.3977
56	S	G	-1.3340
57	N	G	-1.9066
58	K	G	-2.0377
59	K	G	-1.4083
60	Y	G	-1.2336
61	A	G	-1.4788
62	D	G	-2.4977
63	S	G	-1.7220
64	V	G	0.0000
65	K	G	-2.6114
66	G	G	-1.8151
67	R	G	-1.6686
68	F	G	0.0000
69	T	G	-1.1230
70	I	G	0.0000
71	S	G	-0.7023
72	R	G	-1.0644
73	D	G	-1.7697
74	N	G	-1.6573
75	S	G	-1.6669
76	K	G	-2.3889
77	N	G	-1.4928
78	T	G	-1.0545
79	L	G	0.0000
80	Y	G	-0.5505
81	L	G	0.0000
82	Q	G	-1.4194
83	M	G	0.0000
84	N	G	-2.4452
85	S	G	-2.0362
86	L	G	0.0000
87	R	G	-2.4777
88	A	G	-1.6808
89	E	G	-2.1644
90	D	G	0.0000
91	T	G	-0.6299
92	A	G	0.0000
93	V	G	-0.0251
94	Y	G	0.0000
95	Y	G	0.0000
96	C	G	0.0000
97	A	G	0.0000
98	R	G	-0.7775
99	D	G	0.0000
100	R	G	-1.2766
101	G	G	-0.0340
102	I	G	0.8254
103	A	G	0.3798
104	A	G	0.0327
105	G	G	-0.5059
106	G	G	-0.6018
107	N	G	-0.4833
108	Y	G	0.4131
109	Y	G	0.0000
110	Y	G	0.7170
111	Y	G	0.0699
112	G	G	0.0000
113	M	G	0.0000
114	D	G	-1.2525
115	V	G	-0.3157
116	W	G	-0.3782
117	G	G	0.0000
118	Q	G	-1.1722
119	G	G	-0.4798
120	T	G	-0.3239
121	T	G	-0.0664
122	V	G	0.0000
123	T	G	-0.0042
124	V	G	0.0000
125	S	G	-0.3831
126	S	G	-0.5109