Project name: G3G3

Chain sequence(s)	H: EVQLLESGGGLVQPGGSLRLSCAASGFTFSSSQLSWFRQAPGKEREFVSAVTLVSRTHYADSVKGRFTISRDDAKNTLYLQMNSLKPEDTAVYYCVARAAWGTDYREQGYWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:29)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:30)

• Minimal score value: -2.7841
• Maximal score value: 1.5106
• Average score: -0.6629
• Total score value: -80.2118

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9340
2	V	H	-0.9049
3	Q	H	-0.8862
4	L	H	0.0000
5	L	H	0.9572
6	E	H	-0.0219
7	S	H	-0.4395
8	G	H	-0.9221
9	G	H	-0.5229
11	G	H	0.2146
12	L	H	1.1215
13	V	H	-0.0197
14	Q	H	-1.3740
15	P	H	-1.6527
16	G	H	-1.4398
17	G	H	-0.9739
18	S	H	-1.0575
19	L	H	-0.5010
20	R	H	-1.2541
21	L	H	0.0000
22	S	H	-0.2023
23	C	H	0.0000
24	A	H	-0.2861
25	A	H	0.0000
26	S	H	-0.7837
27	G	H	-0.9984
28	F	H	-0.3141
29	T	H	-0.2650
30	F	H	0.0000
35	S	H	-0.1542
36	S	H	0.3655
37	S	H	0.0000
38	Q	H	0.1361
39	L	H	0.0000
40	S	H	0.0000
41	W	H	0.0000
42	F	H	0.4085
43	R	H	0.0000
44	Q	H	-1.2949
45	A	H	-1.4047
46	P	H	-1.0574
47	G	H	-1.4778
48	K	H	-2.2849
49	E	H	-2.7841
50	R	H	-1.8139
51	E	H	-1.0584
52	F	H	0.0592
53	V	H	0.0000
54	S	H	0.0000
55	A	H	-0.3904
56	V	H	0.0000
57	T	H	0.1406
58	L	H	1.1650
59	V	H	1.5106
63	S	H	-0.1124
64	R	H	-1.4069
65	T	H	-0.9500
66	H	H	-1.3768
67	Y	H	-1.0438
68	A	H	-1.2953
69	D	H	-2.5270
70	S	H	-1.7505
71	V	H	0.0000
72	K	H	-2.7565
74	G	H	-1.8086
75	R	H	-1.6037
76	F	H	0.0000
77	T	H	-0.7890
78	I	H	0.0000
79	S	H	-0.6508
80	R	H	-1.0709
81	D	H	-1.9761
82	D	H	-2.0009
83	A	H	-1.6373
84	K	H	-2.5920
85	N	H	-2.2063
86	T	H	-1.3040
87	L	H	0.0000
88	Y	H	-0.3122
89	L	H	0.0000
90	Q	H	-0.7801
91	M	H	0.0000
92	N	H	-1.2995
93	S	H	-1.3570
94	L	H	0.0000
95	K	H	-2.5445
96	P	H	-1.9625
97	E	H	-2.3574
98	D	H	0.0000
99	T	H	-0.8473
100	A	H	0.0000
101	V	H	-0.1762
102	Y	H	0.0000
103	Y	H	0.2100
104	C	H	0.0000
105	V	H	0.0000
106	A	H	0.0000
107	R	H	0.0000
108	A	H	-0.4868
109	A	H	-0.5557
110	W	H	-0.2269
111	G	H	-0.6878
111A	T	H	-0.8382
112A	D	H	-1.8443
112	Y	H	-0.6576
113	R	H	-2.0797
114	E	H	-1.5719
115	Q	H	-1.4056
116	G	H	-0.4215
117	Y	H	0.4685
118	W	H	0.8347
119	G	H	0.1388
120	Q	H	-0.9229
121	G	H	-0.4134
122	T	H	-0.5853
123	Q	H	-0.6994
124	V	H	0.0000
125	T	H	-0.2151
126	V	H	0.0000
127	S	H	-0.7306
128	S	H	-0.6299