Project name: 1350

Chain sequence(s)	H: EVQLLESGGGSVQPGGSLRLSCAASGVTYSHYWLAWFRQAPGKEREGVAAIYTNDGTTYYGDSVKGRFTISLDNSKNTLYLQMSSLTAEDTAVYYCALRINDGSWFSPLQPYHYNYRGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:28)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:29)

• Minimal score value: -3.316
• Maximal score value: 1.7677
• Average score: -0.7617
• Total score value: -96.734

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1013
2	V	H	0.0000
3	Q	H	-1.6991
4	L	H	0.0000
5	L	H	0.3290
6	E	H	0.0000
7	S	H	-0.5918
8	G	H	-1.1413
9	G	H	-1.0429
11	G	H	-0.7886
12	S	H	-0.6679
13	V	H	-0.7476
14	Q	H	-1.5500
15	P	H	-1.3718
16	G	H	-1.0801
17	G	H	-0.9153
18	S	H	-0.9783
19	L	H	-1.1202
20	R	H	-1.9931
21	L	H	0.0000
22	S	H	-0.3520
23	C	H	0.0000
24	A	H	-0.2355
25	A	H	-0.6339
26	S	H	-0.7937
27	G	H	-0.9235
28	V	H	-0.4582
29	T	H	-0.0576
30	Y	H	-0.0906
35	S	H	-1.0319
36	H	H	-1.5606
37	Y	H	0.0000
38	W	H	0.0000
39	L	H	0.0000
40	A	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.7016
45	A	H	-1.6622
46	P	H	-1.3108
47	G	H	-1.8092
48	K	H	-3.1777
49	E	H	-3.3160
50	R	H	-2.1553
51	E	H	-2.1357
52	G	H	-1.1415
53	V	H	0.0000
54	A	H	0.0000
55	A	H	0.0000
56	I	H	0.0000
57	Y	H	-0.6351
58	T	H	-1.5090
59	N	H	-2.5178
62	D	H	-2.6213
63	G	H	-1.4635
64	T	H	-0.6741
65	T	H	-0.1183
66	Y	H	0.1338
67	Y	H	-0.7148
68	G	H	-1.3398
69	D	H	-2.3903
70	S	H	-1.8719
71	V	H	0.0000
72	K	H	-2.5520
74	G	H	-1.7210
75	R	H	-1.3034
76	F	H	0.0000
77	T	H	-0.7200
78	I	H	0.0000
79	S	H	-0.1876
80	L	H	-0.5810
81	D	H	-1.5276
82	N	H	-2.2302
83	S	H	-1.8440
84	K	H	-2.5371
85	N	H	-1.9024
86	T	H	-1.0165
87	L	H	0.0000
88	Y	H	-0.2262
89	L	H	0.0000
90	Q	H	-0.9865
91	M	H	0.0000
92	S	H	-0.8794
93	S	H	-0.8557
94	L	H	0.0000
95	T	H	-1.1423
96	A	H	-1.1617
97	E	H	-1.8673
98	D	H	0.0000
99	T	H	-0.7075
100	A	H	0.0000
101	V	H	-0.1801
102	Y	H	0.0000
103	Y	H	-0.5185
104	C	H	0.0000
105	A	H	0.0000
106	L	H	0.0000
107	R	H	0.0000
108	I	H	-0.4558
109	N	H	-1.5814
110	D	H	-2.1912
111	G	H	-1.1808
111A	S	H	-0.0132
111B	W	H	1.4049
111C	F	H	1.7677
112D	S	H	1.1010
112C	P	H	0.0000
112B	L	H	0.3261
112A	Q	H	-0.4853
112	P	H	-0.6090
113	Y	H	0.7106
114	H	H	-0.1928
115	Y	H	0.0000
116	N	H	-1.1661
117	Y	H	-1.1370
118	R	H	-1.7270
119	G	H	-1.0519
120	Q	H	-1.3442
121	G	H	-0.6983
122	T	H	-0.5433
123	Q	H	-0.8026
124	V	H	0.0000
125	T	H	-0.7281
126	V	H	0.0000
127	S	H	-0.9746
128	S	H	-0.7838