| Chain sequence(s) |
A: MLGAVETANPATGVQEGLDSLAATLTQKMEAARAEMAAKLRESADGRFDRMERKLGEMAAHVQAAEQRSAQAIERMGREIAGVADAFNRRVHAAESRNASAIEQVGGEVARIAASVEHKLNRADSAQAQALEKLGGEIARITEKLAERIGSAERRNAAAIDDVGEQVARVTERLNQRHERSA
C: MLGAVETANPATGVQEGLDSLAATLTQKMEAARLEMAAKLRESADGRFDRMERKLGEMAAHVQAAEQRSAQAIERMGREIVGVADAFNRRVHAAESRNASAIEQVGGEVARIAASVEHKLNRADSVQAQALEKLGGEIARITEKLAERIGSAERRNALAIDDVGEQVARVTERLNQRHERSA B: MLGAVETANPATGVQEGLDSLAATLTQKMEAARLEMAAKLRESADGRFDRMERKLGEMAAHVQAAEQRSAQAIERMGREIVGVADAFNRRVHAAESRNASAIEQVGGEVARIAASVEHKLNRADSVQAQALEKLGGEIARITEKLAERIGSAERRNALAIDDVGEQVARVTERLNQRHERSA input PDB |
| Selected Chain(s) | A,B,C |
| Distance of aggregation | 5 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | LA158B,LA34C,LA34B,LA158C,MA1A,LA2A,VA5A,QA127B,VA126B,LA2C,MA1C,VA5C,VA83A,LA21C,LA21A,VA81B,VA83B,VA81C,VA83C,LA21B,AA4B,VA5B,MA1B,LA2B,VA126C,QA127C |
| Energy difference between WT (input) and mutated protein (by FoldX) | 9.59374 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with all chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:00)
[INFO] FoldX: Building mutant model (00:04:19)
[INFO] FoldX: Starting FoldX energy minimalization (00:05:11)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:09:11)
[INFO] Main: Simulation completed successfully. (00:09:15)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | A | A | 0.0690 | mutated: MA1A |
| 2 | A | A | -0.0168 | mutated: LA2A |
| 3 | G | A | -0.4447 | |
| 4 | A | A | -0.0176 | |
| 5 | A | A | -0.2695 | mutated: VA5A |
| 6 | E | A | -1.8221 | |
| 7 | T | A | -0.3958 | |
| 8 | A | A | -0.1897 | |
| 9 | N | A | -1.2894 | |
| 10 | P | A | -0.3731 | |
| 11 | A | A | -0.0123 | |
| 12 | T | A | -0.1505 | |
| 13 | G | A | -0.4456 | |
| 14 | V | A | -0.1136 | |
| 15 | Q | A | -1.4907 | |
| 16 | E | A | -2.0556 | |
| 17 | G | A | -0.4433 | |
| 18 | L | A | 0.0000 | |
| 19 | D | A | -1.8278 | |
| 20 | S | A | -0.5345 | |
| 21 | A | A | -0.0286 | mutated: LA21A |
| 22 | A | A | 0.0239 | |
| 23 | A | A | 0.0489 | |
| 24 | T | A | -0.0550 | |
| 25 | L | A | 0.0000 | |
| 26 | T | A | -0.2317 | |
| 27 | Q | A | -1.3408 | |
| 28 | K | A | -0.9965 | |
| 29 | M | A | 0.0000 | |
| 30 | E | A | -0.9643 | |
| 31 | A | A | -0.1212 | |
| 32 | A | A | -0.0667 | |
| 33 | R | A | -0.5599 | |
| 34 | A | A | -0.3160 | |
| 35 | E | A | -1.4858 | |
| 36 | M | A | 0.0000 | |
| 37 | A | A | 0.0181 | |
| 38 | A | A | -0.2662 | |
| 39 | K | A | -1.6647 | |
| 40 | L | A | -0.2832 | |
| 41 | R | A | -1.0955 | |
| 42 | E | A | -1.9899 | |
| 43 | S | A | -0.4715 | |
| 44 | A | A | -0.1620 | |
| 45 | D | A | -0.8342 | |
| 46 | G | A | -0.4162 | |
| 47 | R | A | -0.3963 | |
| 48 | F | A | 0.0000 | |
| 49 | D | A | -2.1166 | |
| 50 | R | A | -2.1377 | |
| 51 | M | A | -0.5273 | |
| 52 | E | A | -2.1266 | |
| 53 | R | A | -2.3097 | |
| 54 | K | A | -1.1109 | |
| 55 | L | A | 0.0000 | |
| 56 | G | A | -0.6709 | |
| 57 | E | A | -1.7923 | |
| 58 | M | A | 0.0000 | |
| 59 | A | A | 0.0289 | |
| 60 | A | A | -0.1148 | |
| 61 | H | A | -0.9797 | |
| 62 | V | A | 0.0000 | |
| 63 | Q | A | -1.1948 | |
| 64 | A | A | -0.1950 | |
| 65 | A | A | -0.0631 | |
| 66 | E | A | -0.6452 | |
| 67 | Q | A | -1.6056 | |
| 68 | R | A | -2.0632 | |
| 69 | S | A | -0.3549 | |
| 70 | A | A | -0.1322 | |
| 71 | Q | A | -0.8606 | |
| 72 | A | A | -0.1017 | |
| 73 | I | A | -0.0633 | |
| 74 | E | A | -2.0249 | |
| 75 | R | A | -2.1573 | |
| 76 | M | A | 0.0000 | |
| 77 | G | A | -0.4641 | |
| 78 | R | A | -2.1955 | |
| 79 | E | A | -2.1893 | |
| 80 | I | A | 0.0000 | |
| 81 | A | A | -0.0080 | |
| 82 | G | A | -0.5375 | |
| 83 | A | A | -0.0467 | mutated: VA83A |
| 84 | A | A | -0.2253 | |
| 85 | D | A | -1.3331 | |
| 86 | A | A | -0.1991 | |
| 87 | F | A | 0.0000 | |
| 88 | N | A | -0.8901 | |
| 89 | R | A | -2.1556 | |
| 90 | R | A | -1.4999 | |
| 91 | V | A | 0.0000 | |
| 92 | H | A | -0.9795 | |
| 93 | A | A | -0.1196 | |
| 94 | A | A | -0.0409 | |
| 95 | E | A | -0.3494 | |
| 96 | S | A | -0.3504 | |
| 97 | R | A | -0.7054 | |
| 98 | N | A | 0.0000 | |
| 99 | A | A | -0.0092 | |
| 100 | S | A | -0.2054 | |
| 101 | A | A | 0.0144 | |
| 102 | I | A | -0.1002 | |
| 103 | E | A | -1.9954 | |
| 104 | Q | A | -1.4935 | |
| 105 | V | A | -0.1847 | |
| 106 | G | A | -0.1403 | |
| 107 | G | A | -0.3463 | |
| 108 | E | A | -1.2869 | |
| 109 | V | A | 0.0000 | |
| 110 | A | A | -0.2709 | |
| 111 | R | A | -1.7765 | |
| 112 | I | A | -0.0128 | |
| 113 | A | A | 0.0790 | |
| 114 | A | A | 0.0224 | |
| 115 | S | A | -0.0903 | |
| 116 | V | A | 0.0000 | |
| 117 | E | A | -1.1146 | |
| 118 | H | A | -1.3303 | |
| 119 | K | A | -1.1027 | |
| 120 | L | A | -0.2447 | |
| 121 | N | A | -1.5772 | |
| 122 | R | A | -2.0700 | |
| 123 | A | A | -0.6305 | |
| 124 | D | A | -1.7768 | |
| 125 | S | A | -0.4114 | |
| 126 | A | A | -0.0028 | |
| 127 | Q | A | -0.1639 | |
| 128 | A | A | -0.2228 | |
| 129 | Q | A | -1.1914 | |
| 130 | A | A | -0.1620 | |
| 131 | L | A | -0.0992 | |
| 132 | E | A | -2.0864 | |
| 133 | K | A | -2.0285 | |
| 134 | L | A | 0.0000 | |
| 135 | G | A | -0.1446 | |
| 136 | G | A | -0.3167 | |
| 137 | E | A | -1.1433 | |
| 138 | I | A | 0.0000 | |
| 139 | A | A | -0.2947 | |
| 140 | R | A | -1.7891 | |
| 141 | I | A | -0.0619 | |
| 142 | T | A | -0.2905 | |
| 143 | E | A | -2.1276 | |
| 144 | K | A | -2.0277 | |
| 145 | L | A | 0.0000 | |
| 146 | A | A | -0.3207 | |
| 147 | E | A | -2.0532 | |
| 148 | R | A | -1.6397 | |
| 149 | I | A | 0.0000 | |
| 150 | G | A | -0.1481 | |
| 151 | S | A | -0.0846 | |
| 152 | A | A | -0.1448 | |
| 153 | E | A | -1.1101 | |
| 154 | R | A | -2.3149 | |
| 155 | R | A | -2.1754 | |
| 156 | N | A | 0.0000 | |
| 157 | A | A | 0.0169 | |
| 158 | A | A | 0.0366 | |
| 159 | A | A | 0.0556 | |
| 160 | I | A | -0.1185 | |
| 161 | D | A | -2.0860 | |
| 162 | D | A | -2.1115 | |
| 163 | V | A | 0.0000 | |
| 164 | G | A | -0.5495 | |
| 165 | E | A | -1.5684 | |
| 166 | Q | A | -0.7434 | |
| 167 | V | A | 0.0000 | |
| 168 | A | A | -0.3533 | |
| 169 | R | A | -1.4790 | |
| 170 | V | A | 0.0000 | |
| 171 | T | A | -0.3113 | |
| 172 | E | A | -1.8053 | |
| 173 | R | A | -1.4364 | |
| 174 | L | A | 0.0000 | |
| 175 | N | A | -0.9108 | |
| 176 | Q | A | -0.8400 | |
| 177 | R | A | -1.3092 | |
| 178 | H | A | -1.2731 | |
| 179 | E | A | -2.2829 | |
| 180 | R | A | -2.2068 | |
| 181 | S | A | -0.5338 | |
| 182 | A | A | 0.0191 | |
| 1 | A | B | 0.0693 | mutated: MA1B |
| 2 | A | B | -0.0175 | mutated: LA2B |
| 3 | G | B | -0.4443 | |
| 4 | A | B | -0.0196 | mutated: AA4B |
| 5 | A | B | -0.2739 | mutated: VA5B |
| 6 | E | B | -1.8221 | |
| 7 | T | B | -0.4005 | |
| 8 | A | B | -0.1932 | |
| 9 | N | B | -1.2810 | |
| 10 | P | B | -0.3280 | |
| 11 | A | B | -0.0002 | |
| 12 | T | B | -0.2594 | |
| 13 | G | B | -0.4680 | |
| 14 | V | B | 0.0000 | |
| 15 | Q | B | -1.5122 | |
| 16 | E | B | -2.0518 | |
| 17 | G | B | -0.4109 | |
| 18 | L | B | -0.1811 | |
| 19 | D | B | -1.7975 | |
| 20 | S | B | -0.5320 | |
| 21 | A | B | -0.0277 | mutated: LA21B |
| 22 | A | B | -0.1561 | |
| 23 | A | B | 0.0479 | |
| 24 | T | B | -0.0589 | |
| 25 | L | B | 0.0000 | |
| 26 | T | B | -0.2355 | |
| 27 | Q | B | -1.3701 | |
| 28 | K | B | -1.1576 | |
| 29 | M | B | 0.0000 | |
| 30 | E | B | -0.9439 | |
| 31 | A | B | -0.1169 | |
| 32 | A | B | -0.0518 | |
| 33 | R | B | -0.4973 | |
| 34 | A | B | -0.3246 | mutated: LA34B |
| 35 | E | B | -1.5987 | |
| 36 | M | B | 0.0000 | |
| 37 | A | B | 0.0190 | |
| 38 | A | B | -0.2180 | |
| 39 | K | B | -1.4329 | |
| 40 | L | B | 0.0000 | |
| 41 | R | B | -2.0349 | |
| 42 | E | B | -2.1359 | |
| 43 | S | B | -0.3661 | |
| 44 | A | B | -0.0572 | |
| 45 | D | B | -0.3571 | |
| 46 | G | B | -0.3874 | |
| 47 | R | B | -0.7951 | |
| 48 | F | B | 0.0000 | |
| 49 | D | B | -2.0900 | |
| 50 | R | B | -2.1577 | |
| 51 | M | B | 0.0000 | |
| 52 | E | B | -0.7898 | |
| 53 | R | B | -2.0780 | |
| 54 | K | B | -1.1794 | |
| 55 | L | B | 0.0000 | |
| 56 | G | B | -0.6727 | |
| 57 | E | B | -1.8820 | |
| 58 | M | B | 0.0000 | |
| 59 | A | B | 0.0283 | |
| 60 | A | B | -0.0260 | |
| 61 | H | B | -0.4458 | |
| 62 | V | B | -0.1148 | |
| 63 | Q | B | -1.1609 | |
| 64 | A | B | -0.1973 | |
| 65 | A | B | -0.1885 | |
| 66 | E | B | -1.3059 | |
| 67 | Q | B | -1.7221 | |
| 68 | R | B | -2.0620 | |
| 69 | S | B | -0.3568 | |
| 70 | A | B | -0.1482 | |
| 71 | Q | B | -0.9083 | |
| 72 | A | B | -0.1156 | |
| 73 | I | B | -0.0648 | |
| 74 | E | B | -1.8350 | |
| 75 | R | B | -2.1216 | |
| 76 | M | B | 0.0000 | |
| 77 | G | B | -0.5214 | |
| 78 | R | B | -2.2044 | |
| 79 | E | B | -2.1870 | |
| 80 | I | B | 0.0000 | |
| 81 | A | B | -0.0059 | mutated: VA81B |
| 82 | G | B | -0.5299 | |
| 83 | A | B | -0.0448 | mutated: VA83B |
| 84 | A | B | -0.2735 | |
| 85 | D | B | -1.6624 | |
| 86 | A | B | -0.2537 | |
| 87 | F | B | 0.0000 | |
| 88 | N | B | -1.0072 | |
| 89 | R | B | -2.1132 | |
| 90 | R | B | -1.3072 | |
| 91 | V | B | 0.0000 | |
| 92 | H | B | -0.9807 | |
| 93 | A | B | -0.1249 | |
| 94 | A | B | -0.0792 | |
| 95 | E | B | -0.5605 | |
| 96 | S | B | -0.3947 | |
| 97 | R | B | -0.7858 | |
| 98 | N | B | 0.0000 | |
| 99 | A | B | -0.0235 | |
| 100 | S | B | -0.2080 | |
| 101 | A | B | 0.0162 | |
| 102 | I | B | -0.0880 | |
| 103 | E | B | -1.9922 | |
| 104 | Q | B | -1.4911 | |
| 105 | V | B | -0.0525 | |
| 106 | G | B | -0.1470 | |
| 107 | G | B | -0.3169 | |
| 108 | E | B | -1.1592 | |
| 109 | V | B | 0.0000 | |
| 110 | A | B | -0.2686 | |
| 111 | R | B | -1.7804 | |
| 112 | I | B | -0.0375 | |
| 113 | A | B | 0.0722 | |
| 114 | A | B | 0.0195 | |
| 115 | S | B | -0.1038 | |
| 116 | V | B | 0.0000 | |
| 117 | E | B | -1.0944 | |
| 118 | H | B | -1.2594 | |
| 119 | K | B | -0.7574 | |
| 120 | L | B | 0.0000 | |
| 121 | N | B | -1.4846 | |
| 122 | R | B | -1.3999 | |
| 123 | A | B | -0.5211 | |
| 124 | D | B | -1.8255 | |
| 125 | S | B | -0.5223 | |
| 126 | A | B | 0.0228 | mutated: VA126B |
| 127 | A | B | 0.0322 | mutated: QA127B |
| 128 | A | B | -0.1628 | |
| 129 | Q | B | -1.1572 | |
| 130 | A | B | -0.1600 | |
| 131 | L | B | -0.1075 | |
| 132 | E | B | -2.0892 | |
| 133 | K | B | -2.0015 | |
| 134 | L | B | -0.1808 | |
| 135 | G | B | -0.1481 | |
| 136 | G | B | -0.4421 | |
| 137 | E | B | -1.8080 | |
| 138 | I | B | 0.0000 | |
| 139 | A | B | -0.2922 | |
| 140 | R | B | -1.7838 | |
| 141 | I | B | -0.0348 | |
| 142 | T | B | -0.2839 | |
| 143 | E | B | -2.1279 | |
| 144 | K | B | -2.0282 | |
| 145 | L | B | 0.0000 | |
| 146 | A | B | -0.3013 | |
| 147 | E | B | -2.0491 | |
| 148 | R | B | -1.6334 | |
| 149 | I | B | 0.0000 | |
| 150 | G | B | -0.0587 | |
| 151 | S | B | -0.0624 | |
| 152 | A | B | -0.0696 | |
| 153 | E | B | -0.6936 | |
| 154 | R | B | -2.2410 | |
| 155 | R | B | -2.1758 | |
| 156 | N | B | 0.0000 | |
| 157 | A | B | 0.0497 | |
| 158 | A | B | 0.0683 | mutated: LA158B |
| 159 | A | B | 0.0652 | |
| 160 | I | B | -0.1040 | |
| 161 | D | B | -2.0819 | |
| 162 | D | B | -2.1099 | |
| 163 | V | B | 0.0000 | |
| 164 | G | B | -0.5828 | |
| 165 | E | B | -1.6906 | |
| 166 | Q | B | -0.6936 | |
| 167 | V | B | 0.0000 | |
| 168 | A | B | -0.2097 | |
| 169 | R | B | -1.3646 | |
| 170 | V | B | 0.0000 | |
| 171 | T | B | -0.3509 | |
| 172 | E | B | -2.0513 | |
| 173 | R | B | -1.5991 | |
| 174 | L | B | 0.0000 | |
| 175 | N | B | -1.4425 | |
| 176 | Q | B | -1.2555 | |
| 177 | R | B | -0.7387 | |
| 178 | H | B | -1.3867 | |
| 179 | E | B | -2.3251 | |
| 180 | R | B | -2.2067 | |
| 181 | S | B | -0.5395 | |
| 182 | A | B | 0.0193 | |
| 1 | A | C | 0.0691 | mutated: MA1C |
| 2 | A | C | -0.0168 | mutated: LA2C |
| 3 | G | C | -0.4446 | |
| 4 | A | C | -0.0181 | |
| 5 | A | C | -0.2673 | mutated: VA5C |
| 6 | E | C | -1.8223 | |
| 7 | T | C | -0.4001 | |
| 8 | A | C | -0.1909 | |
| 9 | N | C | -1.2846 | |
| 10 | P | C | -0.3478 | |
| 11 | A | C | -0.0041 | |
| 12 | T | C | -0.1504 | |
| 13 | G | C | -0.4792 | |
| 14 | V | C | 0.0000 | |
| 15 | Q | C | -1.3089 | |
| 16 | E | C | -2.0187 | |
| 17 | G | C | -0.4542 | |
| 18 | L | C | 0.0000 | |
| 19 | D | C | -1.8268 | |
| 20 | S | C | -0.5358 | |
| 21 | A | C | -0.0271 | mutated: LA21C |
| 22 | A | C | -0.1559 | |
| 23 | A | C | 0.0481 | |
| 24 | T | C | -0.0593 | |
| 25 | L | C | 0.0000 | |
| 26 | T | C | -0.2383 | |
| 27 | Q | C | -1.3826 | |
| 28 | K | C | -1.2154 | |
| 29 | M | C | 0.0000 | |
| 30 | E | C | -1.1191 | |
| 31 | A | C | -0.1515 | |
| 32 | A | C | -0.0457 | |
| 33 | R | C | -0.4448 | |
| 34 | A | C | -0.2841 | mutated: LA34C |
| 35 | E | C | -1.5225 | |
| 36 | M | C | 0.0000 | |
| 37 | A | C | 0.0121 | |
| 38 | A | C | -0.2678 | |
| 39 | K | C | -1.6631 | |
| 40 | L | C | -0.2915 | |
| 41 | R | C | -1.1968 | |
| 42 | E | C | -1.9941 | |
| 43 | S | C | -0.3904 | |
| 44 | A | C | -0.2252 | |
| 45 | D | C | -1.2598 | |
| 46 | G | C | -0.4657 | |
| 47 | R | C | -0.2329 | |
| 48 | F | C | 0.0000 | |
| 49 | D | C | -1.6580 | |
| 50 | R | C | -2.0808 | |
| 51 | M | C | 0.0000 | |
| 52 | E | C | -2.1486 | |
| 53 | R | C | -2.3289 | |
| 54 | K | C | -1.2260 | |
| 55 | L | C | 0.0000 | |
| 56 | G | C | -0.6929 | |
| 57 | E | C | -1.8856 | |
| 58 | M | C | 0.0000 | |
| 59 | A | C | 0.0261 | |
| 60 | A | C | -0.0448 | |
| 61 | H | C | -0.5838 | |
| 62 | V | C | 0.0000 | |
| 63 | Q | C | -1.1953 | |
| 64 | A | C | -0.1979 | |
| 65 | A | C | -0.1009 | |
| 66 | E | C | -0.8334 | |
| 67 | Q | C | -1.6396 | |
| 68 | R | C | -2.0640 | |
| 69 | S | C | -0.3565 | |
| 70 | A | C | -0.1756 | |
| 71 | Q | C | -1.1871 | |
| 72 | A | C | -0.1525 | |
| 73 | I | C | -0.0668 | |
| 74 | E | C | -2.1067 | |
| 75 | R | C | -2.1723 | |
| 76 | M | C | 0.0000 | |
| 77 | G | C | -0.4909 | |
| 78 | R | C | -2.0490 | |
| 79 | E | C | -2.1608 | |
| 80 | I | C | 0.0000 | |
| 81 | A | C | -0.0074 | mutated: VA81C |
| 82 | G | C | -0.5366 | |
| 83 | A | C | -0.0490 | mutated: VA83C |
| 84 | A | C | -0.2167 | |
| 85 | D | C | -1.3416 | |
| 86 | A | C | -0.1880 | |
| 87 | F | C | 0.0000 | |
| 88 | N | C | -0.9688 | |
| 89 | R | C | -2.0201 | |
| 90 | R | C | -0.8016 | |
| 91 | V | C | 0.0000 | |
| 92 | H | C | -0.9851 | |
| 93 | A | C | -0.1502 | |
| 94 | A | C | -0.0386 | |
| 95 | E | C | -0.3033 | |
| 96 | S | C | -0.5290 | |
| 97 | R | C | -1.8708 | |
| 98 | N | C | 0.0000 | |
| 99 | A | C | -0.0251 | |
| 100 | S | C | -0.2079 | |
| 101 | A | C | 0.0177 | |
| 102 | I | C | -0.0904 | |
| 103 | E | C | -1.9939 | |
| 104 | Q | C | -1.4936 | |
| 105 | V | C | -0.1847 | |
| 106 | G | C | -0.1362 | |
| 107 | G | C | -0.3407 | |
| 108 | E | C | -1.2861 | |
| 109 | V | C | 0.0000 | |
| 110 | A | C | -0.2699 | |
| 111 | R | C | -1.7949 | |
| 112 | I | C | -0.1173 | |
| 113 | A | C | 0.0578 | |
| 114 | A | C | 0.0216 | |
| 115 | S | C | -0.0944 | |
| 116 | V | C | 0.0000 | |
| 117 | E | C | -1.1335 | |
| 118 | H | C | -1.3047 | |
| 119 | K | C | -0.9676 | |
| 120 | L | C | 0.0000 | |
| 121 | N | C | -1.6069 | |
| 122 | R | C | -2.0705 | |
| 123 | A | C | -0.4548 | |
| 124 | D | C | -0.8405 | |
| 125 | S | C | -0.3503 | |
| 126 | A | C | 0.0038 | mutated: VA126C |
| 127 | A | C | 0.0242 | mutated: QA127C |
| 128 | A | C | -0.1657 | |
| 129 | Q | C | -1.1001 | |
| 130 | A | C | -0.1456 | |
| 131 | L | C | -0.0953 | |
| 132 | E | C | -2.0872 | |
| 133 | K | C | -2.0010 | |
| 134 | L | C | -0.1726 | |
| 135 | G | C | -0.1439 | |
| 136 | G | C | -0.4423 | |
| 137 | E | C | -1.8171 | |
| 138 | I | C | 0.0000 | |
| 139 | A | C | -0.3058 | |
| 140 | R | C | -1.7761 | |
| 141 | I | C | 0.0150 | |
| 142 | T | C | -0.2754 | |
| 143 | E | C | -2.1276 | |
| 144 | K | C | -2.0277 | |
| 145 | L | C | 0.0000 | |
| 146 | A | C | -0.3002 | |
| 147 | E | C | -1.9589 | |
| 148 | R | C | -1.1257 | |
| 149 | I | C | 0.0000 | |
| 150 | G | C | 0.0000 | |
| 151 | S | C | -0.1986 | |
| 152 | A | C | -0.0891 | |
| 153 | E | C | -0.6648 | |
| 154 | R | C | -2.0255 | |
| 155 | R | C | -1.0080 | |
| 156 | N | C | 0.0000 | |
| 157 | A | C | 0.0522 | |
| 158 | A | C | 0.0681 | mutated: LA158C |
| 159 | A | C | 0.0602 | |
| 160 | I | C | -0.1096 | |
| 161 | D | C | -2.0841 | |
| 162 | D | C | -2.1120 | |
| 163 | V | C | 0.0000 | |
| 164 | G | C | -0.5870 | |
| 165 | E | C | -1.8127 | |
| 166 | Q | C | -0.8333 | |
| 167 | V | C | 0.0000 | |
| 168 | A | C | -0.2131 | |
| 169 | R | C | -1.5264 | |
| 170 | V | C | 0.0000 | |
| 171 | T | C | -0.3136 | |
| 172 | E | C | -1.9236 | |
| 173 | R | C | -1.8690 | |
| 174 | L | C | 0.0000 | |
| 175 | N | C | -0.7810 | |
| 176 | Q | C | -0.7537 | |
| 177 | R | C | -0.5988 | |
| 178 | H | C | -0.9628 | |
| 179 | E | C | -2.2488 | |
| 180 | R | C | -2.2064 | |
| 181 | S | C | -0.5368 | |
| 182 | A | C | 0.0196 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine