Project name: 8706aaf5b1af219

Chain sequence(s)	B: ESKVIQTHTVQVSAGGPLSSITFVWNGDHTLTVPLTLPAGSTVRLVAETE
Selected Chain(s)	B
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with B chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:18)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:19)

• Minimal score value: -2.9706
• Maximal score value: 1.6928
• Average score: -0.5571
• Total score value: -27.8573

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.8550
2	S	B	-2.5703
3	K	B	-2.2539
4	V	B	-0.2658
5	I	B	0.7979
6	Q	B	-0.5940
7	T	B	-0.8749
8	H	B	-1.6480
9	T	B	-1.2438
10	V	B	-0.9246
11	Q	B	-1.4497
12	V	B	-0.6759
13	S	B	-0.7216
14	A	B	-0.6242
15	G	B	-0.6625
16	G	B	-0.5891
17	P	B	-0.4428
18	L	B	-0.1508
19	S	B	-0.0380
20	S	B	0.2655
21	I	B	0.9144
22	T	B	1.2617
23	F	B	1.6928
24	V	B	1.5560
25	W	B	0.3638
26	N	B	-1.3936
27	G	B	-1.4087
28	D	B	-2.3292
29	H	B	-1.1355
30	T	B	0.4303
31	L	B	1.5846
32	T	B	1.1301
33	V	B	0.9558
34	P	B	0.3810
35	L	B	0.5500
36	T	B	0.1051
37	L	B	0.0000
38	P	B	-0.5500
39	A	B	-0.7208
40	G	B	-0.8682
41	S	B	-0.5466
42	T	B	-0.8616
43	V	B	-0.9106
44	R	B	-1.8705
45	L	B	-0.9899
46	V	B	-0.3923
47	A	B	-0.5799
48	E	B	-1.7138
49	T	B	-2.0196
50	E	B	-2.9706