Project name: 1E11

Chain sequence(s)	H: QVQLVESGGGLVQAGDSLRLSCAASGRTFSTYAVGWFRQAPGKEREFVAAINWNGDMTHYADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYCAAESRGSTGWGTTHYEYDYWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:57)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:58)

• Minimal score value: -3.1921
• Maximal score value: 1.1494
• Average score: -0.7389
• Total score value: -93.0981

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.6483
2	V	H	-1.4673
3	Q	H	-1.1359
4	L	H	0.0000
5	V	H	1.1494
6	E	H	0.0000
7	S	H	-0.3852
8	G	H	-0.8331
9	G	H	-0.4958
11	G	H	0.1295
12	L	H	1.1458
13	V	H	-0.1470
14	Q	H	-1.4813
15	A	H	-1.8257
16	G	H	-1.7204
17	D	H	-1.9010
18	S	H	-1.3444
19	L	H	-0.7798
20	R	H	-1.2058
21	L	H	0.0000
22	S	H	-0.1410
23	C	H	0.0000
24	A	H	0.0219
25	A	H	-0.5931
26	S	H	-1.1580
27	G	H	-1.7287
28	R	H	-2.3485
29	T	H	-1.2069
30	F	H	0.0000
35	S	H	-0.8439
36	T	H	-0.5894
37	Y	H	-0.1810
38	A	H	-0.0772
39	V	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.6517
45	A	H	-1.6860
46	P	H	-1.3317
47	G	H	-1.8886
48	K	H	-3.1446
49	E	H	-3.1921
50	R	H	-1.9951
51	E	H	-1.4348
52	F	H	-0.6029
53	V	H	0.0000
54	A	H	0.0000
55	A	H	0.0000
56	I	H	0.0000
57	N	H	-0.2872
58	W	H	-0.2088
59	N	H	-1.4912
62	G	H	-1.2876
63	D	H	-1.6444
64	M	H	0.0189
65	T	H	0.0216
66	H	H	-0.2503
67	Y	H	-0.9528
68	A	H	-1.4194
69	D	H	-2.5552
70	S	H	-1.7884
71	V	H	0.0000
72	K	H	-2.6939
74	G	H	-1.7630
75	R	H	-1.4992
76	F	H	0.0000
77	T	H	-0.7283
78	I	H	0.0000
79	S	H	-0.5670
80	R	H	-1.1066
81	D	H	-1.4262
82	S	H	-1.4217
83	A	H	-1.2721
84	K	H	-2.1403
85	N	H	0.0000
86	T	H	0.0000
87	V	H	0.0000
88	Y	H	-0.3410
89	L	H	0.0000
90	Q	H	-0.7651
91	M	H	0.0000
92	N	H	-1.4171
93	S	H	-1.4300
94	L	H	0.0000
95	K	H	-2.3522
96	P	H	-1.8213
97	E	H	-2.2958
98	D	H	0.0000
99	T	H	-0.7934
100	A	H	0.0000
101	V	H	-0.2098
102	Y	H	0.0000
103	Y	H	0.0294
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	E	H	0.0000
108	S	H	-1.5465
109	R	H	-2.0809
110	G	H	-1.1828
111	S	H	-0.9018
111A	T	H	-0.5163
111B	G	H	-0.3778
111C	W	H	0.1926
112C	G	H	-0.1175
112B	T	H	-0.1061
112A	T	H	-0.1076
112	H	H	-0.5560
113	Y	H	0.3001
114	E	H	-1.0677
115	Y	H	0.0000
116	D	H	-1.9985
117	Y	H	-0.9525
118	W	H	-0.3163
119	G	H	-0.1142
120	Q	H	-0.8072
121	G	H	-0.3552
122	T	H	-0.4535
123	Q	H	-0.6256
124	V	H	0.0000
125	T	H	-0.1809
126	V	H	0.0000
127	S	H	-0.8370
128	S	H	-0.8099