Project name: 87a030b232622e0

Chain sequence(s)	A: AETVESCLAKPHTEVSFTNVWKEGDSRYANYEGCLWSAGGVVVCTGDETQCYGHWVPIGLAIPENEGGGSEGGGSEGGGSEGGGTKPPEYGDTPIPGTTWINPLDGTYPPGTEQNPANPNPSLEESQPLNTFMVQGNRFRNRQGALTVYTGMFTQGTDPVKRYYLYTPLSSRAMYDAYWNGKFRDCAFHSGFNEDPFVCEYQGQSSDLPQPPANA
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:04)
[INFO]       Main:     Simulation completed successfully.                                          (00:04:06)

• Minimal score value: -3.3607
• Maximal score value: 2.3846
• Average score: -0.9493
• Total score value: -204.0951

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-1.6404
2	E	A	-2.3397
3	T	A	-1.7048
4	V	A	0.0000
5	E	A	-2.3051
6	S	A	-1.4606
7	C	A	0.0000
8	L	A	0.0000
9	A	A	-1.2687
10	K	A	-1.1537
11	P	A	-0.9861
12	H	A	-1.4387
13	T	A	-1.3313
14	E	A	-1.7313
15	V	A	-0.2510
16	S	A	0.2422
17	F	A	0.0000
18	T	A	-0.8721
19	N	A	-1.7686
20	V	A	0.0000
21	W	A	0.0000
22	K	A	-2.6186
23	E	A	-2.2091
24	G	A	-1.9892
25	D	A	-2.3913
26	S	A	-1.7280
27	R	A	-1.5862
28	Y	A	0.0000
29	A	A	0.0000
30	N	A	-0.7109
31	Y	A	-0.2203
32	E	A	-1.7030
33	G	A	-1.2633
34	C	A	0.0000
35	L	A	0.0000
36	W	A	0.0000
37	S	A	0.0000
38	A	A	-0.4462
39	G	A	-0.5042
40	G	A	0.1963
41	V	A	2.1651
42	V	A	2.1124
43	V	A	2.3846
44	C	A	0.5226
45	T	A	-0.8305
46	G	A	-1.4975
47	D	A	-2.7669
48	E	A	-2.4881
49	T	A	-2.3456
50	Q	A	-1.4235
51	C	A	0.0000
52	Y	A	1.2595
53	G	A	0.0000
54	H	A	-0.9182
55	W	A	0.0000
56	V	A	0.0000
57	P	A	0.0000
58	I	A	0.0000
59	G	A	0.0000
60	L	A	-0.5204
61	A	A	-0.6182
62	I	A	0.0000
63	P	A	-2.0985
64	E	A	-3.1976
65	N	A	-3.1621
66	E	A	-3.3607
67	G	A	-2.4703
68	G	A	-2.5682
69	G	A	-1.9465
70	S	A	0.0000
71	E	A	-2.6005
72	G	A	-2.0563
73	G	A	-1.8235
74	G	A	-2.1307
75	S	A	-1.6545
76	E	A	-2.7914
77	G	A	-2.4987
78	G	A	-2.6814
79	G	A	-2.6643
80	S	A	-2.2754
81	E	A	-2.4510
82	G	A	-1.7611
83	G	A	-2.1596
84	G	A	-2.4488
85	T	A	-2.3725
86	K	A	-2.8842
87	P	A	-1.7184
88	P	A	-1.6061
89	E	A	-2.3242
90	Y	A	-0.9956
91	G	A	-1.5419
92	D	A	-1.9142
93	T	A	-0.7394
94	P	A	0.0000
95	I	A	0.0000
96	P	A	-0.1162
97	G	A	0.0000
98	T	A	-0.1269
99	T	A	0.0513
100	W	A	0.0000
101	I	A	0.0000
102	N	A	0.0000
103	P	A	-0.1121
104	L	A	-0.2401
105	D	A	-1.8607
106	G	A	-1.4263
107	T	A	-1.4183
108	Y	A	0.0000
109	P	A	0.0000
110	P	A	-1.6765
111	G	A	0.0000
112	T	A	0.0000
113	E	A	-2.7222
114	Q	A	-2.2303
115	N	A	0.0000
116	P	A	-1.2491
117	A	A	-0.9157
118	N	A	-1.1568
119	P	A	-1.2212
120	N	A	-1.6140
121	P	A	-0.6700
122	S	A	-0.4496
123	L	A	0.1336
124	E	A	-1.2537
125	E	A	-2.3429
126	S	A	-1.4497
127	Q	A	-1.2556
128	P	A	-0.2973
129	L	A	0.1635
130	N	A	0.0513
131	T	A	0.0000
132	F	A	0.0000
133	M	A	0.0626
134	V	A	0.0000
135	Q	A	-1.5717
136	G	A	-0.7343
137	N	A	-0.6560
138	R	A	-0.4086
139	F	A	0.0000
140	R	A	0.0000
141	N	A	0.0000
142	R	A	-0.6642
143	Q	A	-0.3779
144	G	A	0.0000
145	A	A	-0.3063
146	L	A	0.0000
147	T	A	0.0000
148	V	A	0.0000
149	Y	A	0.1623
150	T	A	0.0000
151	G	A	0.5378
152	M	A	1.0786
153	F	A	0.7364
154	T	A	-0.5182
155	Q	A	-1.5684
156	G	A	-1.3790
157	T	A	-1.0325
158	D	A	-1.7473
159	P	A	-0.9968
160	V	A	-0.3034
161	K	A	-1.6510
162	R	A	-1.7669
163	Y	A	-0.9544
164	Y	A	0.0798
165	L	A	0.6710
166	Y	A	0.0000
167	T	A	-0.2913
168	P	A	-0.6259
169	L	A	0.0000
170	S	A	-1.4341
171	S	A	-1.7130
172	R	A	-2.4546
173	A	A	-1.4263
174	M	A	0.0000
175	Y	A	0.0000
176	D	A	-1.6059
177	A	A	0.0000
178	Y	A	0.0000
179	W	A	0.0000
180	N	A	-1.8519
181	G	A	-1.5958
182	K	A	-2.3823
183	F	A	-2.2369
184	R	A	-3.0948
185	D	A	-2.1110
186	C	A	-0.7060
187	A	A	-0.0135
188	F	A	0.6537
189	H	A	-0.2671
190	S	A	-0.5006
191	G	A	-0.3984
192	F	A	0.1512
193	N	A	-2.1616
194	E	A	-3.0079
195	D	A	-2.4999
196	P	A	0.0000
197	F	A	-0.0240
198	V	A	0.4691
199	C	A	0.0000
200	E	A	-2.8252
201	Y	A	-2.4963
202	Q	A	-2.4596
203	G	A	-2.0436
204	Q	A	-2.3046
205	S	A	-2.1093
206	S	A	-1.8913
207	D	A	-2.5782
208	L	A	0.0000
209	P	A	-1.4772
210	Q	A	-1.6178
211	P	A	0.0000
212	P	A	-0.7595
213	A	A	-0.7825
214	N	A	-1.2487
215	A	A	-0.6124