Project name: HIL6

Chain sequence(s)	A: LTSSERIDKQIRYILDGISALRKETCNKSNMCENLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:03:40)
[INFO]       Main:     Simulation completed successfully.                                          (00:03:41)

• Minimal score value: -3.9086
• Maximal score value: 0.7228
• Average score: -1.1742
• Total score value: -184.3444

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
19	L	A	0.7228
20	T	A	-0.1471
21	S	A	-0.9444
22	S	A	-1.2733
23	E	A	-1.8535
24	R	A	-1.4360
25	I	A	0.0000
26	D	A	-2.1380
27	K	A	-1.7479
28	Q	A	0.0000
29	I	A	0.0000
30	R	A	-2.0633
31	Y	A	-0.4506
32	I	A	0.0000
33	L	A	-1.5892
34	D	A	-1.9837
35	G	A	-1.0921
36	I	A	0.0000
37	S	A	-1.7117
38	A	A	-1.5207
39	L	A	0.0000
40	R	A	-2.7539
41	K	A	-3.1181
42	E	A	-2.4728
43	T	A	0.0000
44	C	A	-2.7557
45	N	A	-3.1974
46	K	A	-3.1513
47	S	A	-1.7325
48	N	A	-2.4457
49	M	A	-0.9692
50	C	A	-1.6071
51	E	A	-1.8910
61	N	A	-1.5353
62	L	A	-0.8970
63	N	A	-1.9141
64	L	A	0.0000
65	P	A	-1.6199
66	K	A	-2.1685
67	M	A	-1.6004
68	A	A	-1.7340
69	E	A	-2.7090
70	K	A	-2.6521
71	D	A	0.0000
72	G	A	0.0000
73	C	A	0.0000
74	F	A	-1.3742
75	Q	A	-1.6684
76	S	A	-1.3160
77	G	A	-1.6047
78	F	A	-1.5250
79	N	A	-1.9730
80	E	A	-2.1529
81	E	A	-2.2710
82	T	A	-1.3576
83	C	A	0.0000
84	L	A	0.0000
85	V	A	-0.3089
86	K	A	-0.6217
87	I	A	0.0000
88	I	A	0.0000
89	T	A	-0.1961
90	G	A	0.0000
91	L	A	0.0000
92	L	A	-0.8002
93	E	A	-1.7292
94	F	A	0.0000
95	E	A	-1.0350
96	V	A	0.0000
97	Y	A	0.0000
98	L	A	0.0000
99	E	A	-1.8298
100	Y	A	0.0000
101	L	A	0.0000
102	Q	A	-3.0911
103	N	A	-2.7892
104	R	A	-2.1582
105	F	A	0.0000
106	E	A	-3.1046
107	S	A	-1.9580
108	S	A	-2.4829
109	E	A	-3.9086
110	E	A	-3.6244
111	Q	A	-2.4383
112	A	A	0.0000
113	R	A	-3.2643
114	A	A	-1.6868
115	V	A	0.0000
116	Q	A	0.0000
117	M	A	-0.4738
118	S	A	-0.2025
119	T	A	0.0000
120	K	A	-1.0793
121	V	A	-0.3662
122	L	A	0.0000
123	I	A	0.0000
124	Q	A	-1.9068
125	F	A	-1.4102
126	L	A	0.0000
127	Q	A	-2.6973
128	K	A	-3.2940
129	K	A	-2.4345
130	A	A	0.0000
131	K	A	-3.4999
132	N	A	-2.9344
133	L	A	-2.1942
134	D	A	-2.0972
135	A	A	-0.9890
136	I	A	-0.1276
137	T	A	-0.3993
138	T	A	-0.6717
139	P	A	-1.2975
140	D	A	-1.9145
141	P	A	-1.1553
142	T	A	-0.7705
143	T	A	-0.7703
144	N	A	-1.0125
145	A	A	-0.6944
146	S	A	-0.5974
147	L	A	-0.5039
148	L	A	-0.8967
149	T	A	-1.0747
150	K	A	-1.9122
151	L	A	0.0000
152	Q	A	-1.7374
153	A	A	-1.3874
154	Q	A	-1.5648
155	N	A	-1.6497
156	Q	A	-1.2726
157	W	A	0.4303
158	L	A	0.2545
159	Q	A	0.0000
160	D	A	-0.4256
161	M	A	0.6275
162	T	A	0.0000
163	T	A	0.0000
164	H	A	0.0000
165	L	A	0.0056
166	I	A	0.0000
167	L	A	0.0000
168	R	A	-2.0394
169	S	A	0.0000
170	F	A	0.0000
171	K	A	-2.5742
172	E	A	-3.0309
173	F	A	0.0000
174	L	A	0.0000
175	Q	A	-2.1002
176	S	A	-1.7726
177	S	A	0.0000
178	L	A	-2.0900
179	R	A	-2.6573
180	A	A	0.0000
181	L	A	-1.6363
182	R	A	-2.7207
183	Q	A	-2.0431
184	M	A	-1.1585