Project name: 8c2c487bb185328

Chain sequence(s)	C: EVQLVESGGGLVQPGGSLRLSCAASQSVNAMGWFRQAPGKGRELVAYIVGSYTYNRGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAASTNAVVALLGRFNEEAFDYWGQGTQVTVSS
Selected Chain(s)	C
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with C chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:45)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:46)

• Minimal score value: -2.8275
• Maximal score value: 2.175
• Average score: -0.6923
• Total score value: -82.3827

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	C	-2.2222
2	V	C	0.0000
3	Q	C	-1.4949
4	L	C	0.0000
5	V	C	1.0705
6	E	C	0.0000
7	S	C	-0.4726
8	G	C	-1.0517
9	G	C	-0.7973
10	G	C	0.0517
11	L	C	0.8858
12	V	C	0.0000
13	Q	C	-1.4057
14	P	C	-1.6110
15	G	C	-1.3770
16	G	C	-0.9720
17	S	C	-1.4265
18	L	C	-1.1921
19	R	C	-2.2950
20	L	C	0.0000
21	S	C	-0.4508
22	C	C	0.0000
23	A	C	-0.3386
24	A	C	0.0000
25	S	C	-1.3292
26	Q	C	-1.6732
27	S	C	-1.4885
28	V	C	0.0000
29	N	C	-1.6161
30	A	C	0.0000
31	M	C	0.0000
32	G	C	0.0000
33	W	C	0.0000
34	F	C	0.0000
35	R	C	-1.1948
36	Q	C	-1.8000
37	A	C	-1.7329
38	P	C	-1.2162
39	G	C	-1.7102
40	K	C	-2.7646
41	G	C	-2.4075
42	R	C	-2.5873
43	E	C	-2.1051
44	L	C	-1.1411
45	V	C	0.0000
46	A	C	0.0000
47	Y	C	0.0000
48	I	C	0.0000
49	V	C	0.0000
50	G	C	-0.6791
51	S	C	-0.0587
52	Y	C	0.7720
53	T	C	0.2237
54	Y	C	-0.4822
55	N	C	-1.5334
56	R	C	-2.2628
57	G	C	-1.8224
58	R	C	-1.8084
59	F	C	0.0000
60	T	C	-1.3344
61	I	C	0.0000
62	S	C	-0.7121
63	R	C	-1.4587
64	D	C	-2.0046
65	N	C	-2.7186
66	A	C	-1.8854
67	K	C	-2.8275
68	R	C	-2.6833
69	M	C	-1.3567
70	V	C	0.0000
71	Y	C	-0.7246
72	L	C	0.0000
73	Q	C	-1.7053
74	M	C	0.0000
75	N	C	-1.6385
76	S	C	-1.2559
77	L	C	0.0000
78	R	C	-2.2643
79	A	C	-1.7114
80	E	C	-2.2177
81	D	C	0.0000
82	T	C	-0.8438
83	A	C	0.0000
84	V	C	-0.3580
85	Y	C	0.0000
86	Y	C	-0.1874
87	C	C	0.0000
88	A	C	0.0000
89	A	C	0.0000
90	S	C	0.0000
91	T	C	-1.0422
92	N	C	-0.6649
93	A	C	0.5321
94	V	C	2.1750
95	V	C	1.7596
96	A	C	0.0000
97	L	C	2.1745
98	L	C	1.9141
99	G	C	0.0000
100	R	C	-0.3662
101	F	C	1.0521
102	N	C	-0.5168
103	E	C	-1.9824
104	E	C	-2.2051
105	A	C	0.0000
106	F	C	0.0000
107	D	C	-2.2868
108	Y	C	-1.2095
109	W	C	-0.1670
110	G	C	-0.1354
111	Q	C	-0.8091
112	G	C	0.0000
113	T	C	-0.6370
114	Q	C	-0.9211
115	V	C	0.0000
116	T	C	-0.3110
117	V	C	0.0000
118	S	C	-0.8001
119	S	C	-0.5299